EE05260B1 - Metformiini ja glburiidi kombinatsiooni v„ikese annuse kasutamine 2. tpi suhkrut?ve esimese rea raviks - Google Patents

Metformiini ja glburiidi kombinatsiooni v„ikese annuse kasutamine 2. tpi suhkrut?ve esimese rea raviks

Info

Publication number
EE05260B1
EE05260B1 EEP200200242A EEP200200242A EE05260B1 EE 05260 B1 EE05260 B1 EE 05260B1 EE P200200242 A EEP200200242 A EE P200200242A EE P200200242 A EEP200200242 A EE P200200242A EE 05260 B1 EE05260 B1 EE 05260B1
Authority
EE
Estonia
Prior art keywords
gluride
sugar
treatment
combination
low dose
Prior art date
Application number
EEP200200242A
Other languages
English (en)
Estonian (et)
Inventor
Anne Piper Beth
Original Assignee
Bristol-Myers Squibb Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/432,465 external-priority patent/US6586438B2/en
Application filed by Bristol-Myers Squibb Company filed Critical Bristol-Myers Squibb Company
Publication of EE200200242A publication Critical patent/EE200200242A/xx
Publication of EE05260B1 publication Critical patent/EE05260B1/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Communicable Diseases (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
EEP200200242A 1999-11-03 2000-10-13 Metformiini ja glburiidi kombinatsiooni v„ikese annuse kasutamine 2. tpi suhkrut?ve esimese rea raviks EE05260B1 (et)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/432,465 US6586438B2 (en) 1999-11-03 1999-11-03 Antidiabetic formulation and method
US09/460,920 US7598262B2 (en) 1999-11-03 1999-12-14 Method for treating diabetes
PCT/US2000/028311 WO2001032157A2 (en) 1999-11-03 2000-10-13 Pharmaceutical composition comprising a combination of metformin and glibenclamide

Publications (2)

Publication Number Publication Date
EE200200242A EE200200242A (et) 2003-12-15
EE05260B1 true EE05260B1 (et) 2010-02-15

Family

ID=27029501

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200200242A EE05260B1 (et) 1999-11-03 2000-10-13 Metformiini ja glburiidi kombinatsiooni v„ikese annuse kasutamine 2. tpi suhkrut?ve esimese rea raviks

Country Status (23)

Country Link
EP (1) EP1229918B1 (zh)
JP (1) JP5183844B2 (zh)
KR (1) KR20070089259A (zh)
CN (1) CN1450902A (zh)
AR (1) AR026356A1 (zh)
AT (1) ATE390140T1 (zh)
AU (1) AU780106B2 (zh)
BR (1) BR0015294A (zh)
CA (1) CA2389928C (zh)
EE (1) EE05260B1 (zh)
HU (1) HU229352B1 (zh)
IL (1) IL149139A0 (zh)
LT (1) LT5058B (zh)
LV (1) LV12910B (zh)
MX (1) MXPA02004282A (zh)
NO (1) NO330026B1 (zh)
NZ (1) NZ518278A (zh)
PL (1) PL199278B1 (zh)
RU (1) RU2275915C2 (zh)
SK (1) SK287810B6 (zh)
TW (1) TWI280125B (zh)
UY (1) UY26424A1 (zh)
WO (1) WO2001032157A2 (zh)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2816840B1 (fr) 2000-11-17 2004-04-09 Flamel Tech Sa Medicament a base de microcapsules d'anti-hyperclycemiant a liberation prolongee et son procede de preparation
FR2825023B1 (fr) * 2001-05-23 2005-04-15 Flamel Tech Sa Forme pharmaceutique orale antidiabetique "une prise par jour"comprenant une biguanide et au moins un autre principe actif
WO2003011273A1 (en) * 2001-07-31 2003-02-13 The Governement Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Metformin in the treatment of hyperglycemic conditions
EP1492511B3 (fr) 2002-04-09 2012-05-02 Flamel Technologies Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee de principe(s) actif(s)
EP1515701B1 (en) 2002-06-17 2014-09-17 Inventia Healthcare Private Limited Process for the manufacture of multilayer tablet compositions comprising thiazolidinedione and biguanide
WO2005046687A1 (en) * 2003-10-30 2005-05-26 Tioga Pharmaceuticals, Inc. Use of selective opiate receptor modulators in the treatment of neuropathy
TWI350751B (en) * 2003-12-19 2011-10-21 Omega Bio Pharma Ip3 Ltd Pharmaceutical compositions for treating diabetes
RU2387445C2 (ru) * 2004-05-03 2010-04-27 ОМЕГА БИО-ФАРМА (Ай.Пи. 3) ЛИМИТЕД Материалы и способы модуляции метаболизма
MY159203A (en) 2007-07-19 2016-12-30 Takeda Pharmaceuticals Co Solid preparation comprising alogliptin and metformin hydrochloride
KR101552187B1 (ko) 2007-09-10 2015-09-10 얀센 파마슈티카 엔.브이. Ｓｇｌｔ 억제제로서 유용한 화합물의 제조 방법
CA2740685C (en) 2008-10-17 2018-09-11 Sanofi-Aventis Deutschland Gmbh Combination of an insulin and a glp-1 agonist
US9056850B2 (en) 2008-10-17 2015-06-16 Janssen Pharmaceutica N.V. Process for the preparation of compounds useful as inhibitors of SGLT
US20110009347A1 (en) 2009-07-08 2011-01-13 Yin Liang Combination therapy for the treatment of diabetes
AU2010317995B2 (en) 2009-11-13 2014-04-17 Sanofi-Aventis Deutschland Gmbh Pharmaceutical composition comprising a GLP-1 agonist, an insulin, and methionine
JP5973918B2 (ja) 2009-11-13 2016-08-23 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング Ｇｌｐ−１アゴニスト及びメチオニンを含む薬学的組成物
JP6227406B2 (ja) 2010-05-11 2017-11-08 ヤンセン ファーマシューティカ エヌ．ベー． ＳＧＬＴの阻害剤としての１−（β−Ｄ−グルコピラノシル）−２−チエニル−メチルベンゼン誘導体を含有する医薬製剤
JP6199186B2 (ja) 2010-08-30 2017-09-20 サノフィ−アベンティス・ドイチュラント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング ２型糖尿病の治療用の医薬の製造のためのａｖｅ００１０の使用
BR112013019744A2 (pt) * 2011-02-02 2016-11-22 Sanofi Aventis Deutschland prevenção de hipoglicemia em pacientes com diabetes mellitus tipo 2
US20120277147A1 (en) * 2011-03-29 2012-11-01 Sanofi-Aventis Deutschland Gmbh Prevention of hypoglycaemia in diabetes mellitus type 2 patients
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
TWI559929B (en) 2011-09-01 2016-12-01 Sanofi Aventis Deutschland Pharmaceutical composition for use in the treatment of a neurodegenerative disease
HRP20230470T1 (hr) 2014-12-12 2023-07-21 Sanofi-Aventis Deutschland Gmbh Formulacija fiksnog omjera inzulin glargin/liksisenatid
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第２型糖尿病病患之治療
US20170071970A1 (en) 2015-09-15 2017-03-16 Janssen Pharmaceutica Nv Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
CN110804017A (zh) * 2019-10-31 2020-02-18 天津大学 磺酰脲化合物与二甲双胍成盐、制备方法和应用
CN113143940A (zh) * 2020-12-30 2021-07-23 成都恒瑞制药有限公司 一种抗糖尿病药物组合物的制备方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3174901A (en) 1963-01-31 1965-03-23 Jan Marcel Didier Aron Samuel Process for the oral treatment of diabetes
DE3833439A1 (de) * 1988-10-01 1991-09-12 Hoechst Ag Verfahren zur mikronisierung von glibenclamid
DK36392D0 (da) 1992-03-19 1992-03-19 Novo Nordisk As Anvendelse af kemisk forbindelse
TWI238064B (en) 1995-06-20 2005-08-21 Takeda Chemical Industries Ltd A pharmaceutical composition for prophylaxis and treatment of diabetes
IT1276130B1 (it) * 1995-11-14 1997-10-27 Gentili Ist Spa Associazione glibenclamide-metformina, composizioni farmaceutiche che la contengono e loro uso nel trattamento del diabete mellito di tipo
CZ298469B6 (cs) 1997-06-18 2007-10-10 Smithkline Beecham Plc Farmaceutický prostredek obsahující 5-[4-/2-(N-methyl-N-(2-pyridyl)amino)ethoxy/benzyl]thiazolidin-2,4-dion a metformin, a lécivo pro lécení diabetesmellitus
CA2312990C (en) * 1997-12-08 2008-04-29 Bristol-Myers Squibb Company Novel salts of metformin and method
ATE250418T1 (de) * 1998-07-15 2003-10-15 Merck Sante Sas Tabletten enthaltend eine kombination von glibenclamid und metformin
EP2620443A1 (en) 2012-01-25 2013-07-31 Galecto Biotech AB Novel galactoside inhibitors of galectins

Also Published As

Publication number Publication date
BR0015294A (pt) 2003-07-15
PL199278B1 (pl) 2008-09-30
JP5183844B2 (ja) 2013-04-17
SK287810B6 (sk) 2011-10-04
LT5058B (lt) 2003-09-25
LT2002063A (en) 2003-06-25
ATE390140T1 (de) 2008-04-15
NZ518278A (en) 2004-10-29
TWI280125B (en) 2007-05-01
AU780106B2 (en) 2005-03-03
NO330026B1 (no) 2011-02-07
HUP0300218A2 (hu) 2003-06-28
CA2389928A1 (en) 2001-05-10
RU2275915C2 (ru) 2006-05-10
EE200200242A (et) 2003-12-15
NO20022087D0 (no) 2002-05-02
WO2001032157A3 (en) 2002-01-24
PL364885A1 (en) 2004-12-27
HUP0300218A3 (en) 2006-02-28
HU229352B1 (en) 2013-11-28
RU2002114820A (ru) 2004-03-10
IL149139A0 (en) 2002-11-10
LV12910B (en) 2003-05-20
NO20022087L (no) 2002-06-24
CN1450902A (zh) 2003-10-22
KR20070089259A (ko) 2007-08-30
SK5002002A3 (en) 2004-05-04
MXPA02004282A (es) 2003-02-17
EP1229918A2 (en) 2002-08-14
AR026356A1 (es) 2003-02-05
WO2001032157A2 (en) 2001-05-10
AU1082601A (en) 2001-05-14
EP1229918B1 (en) 2008-03-26
UY26424A1 (es) 2001-05-31
JP2003519621A (ja) 2003-06-24
CA2389928C (en) 2010-03-23

Similar Documents

Publication Publication Date Title
EE05260B1 (et) Metformiini ja glburiidi kombinatsiooni v„ikese annuse kasutamine 2. tpi suhkrut?ve esimese rea raviks
NO20053106D0 (no) Oral, analgesisk doseringsform med forlenget frigivelse.
DE69514087D1 (de) Pharmazeutisch aktive substituierte aromatische verbindungen
FI910851A (fi) 3-arylkarbonyl-1h-indoler anvaendbara som terapeutiska aemnen.
NO974070L (no) Orale, farmasöytiske doseringsformer omfattende en protonpumpeinhibitor og et prokinetisk middel
ATE312602T1 (de) Orale pharmazeutische dosierungsform mit verlängerter wirkstofffreisetzung
FI923273A0 (fi) Med dubbelminne foersett multiprocessorsystem.
BR0005300B1 (pt) absorvente higiÊnico composto.
ZA993345B (en) Nefazodone dosage form.
NO20005179D0 (no) Medikament behandling
IT1311921B1 (it) Composti farmaceutici.
NO970123D0 (no) Ny kjemisk forbindelse, dens fremstilling og anvendelse som legemiddel
IT1304389B1 (it) Tenditore del tipo a nottolino di arresto senza gioco.
FR2680419B1 (fr) Endoscopes.
IT1307018B1 (it) Agenti antibatterici.
MA26677A1 (fr) Medicaments antiparkinsoniens.
IT1313594B1 (it) Bisplatino complessi attivi per via orale.
FI921164A0 (fi) Med jonstraol steriliserbar odlings- medium, som aer laemplig foer miljoeprovtagningsmedel.
ES1044951Y (es) Tabique perfeccionado.
RU99123655A (ru) Средство для лечения герпеса
ES1029483Y (es) Sembrador perfeccionado.
ES1027737Y (es) Canutillo perfeccionado.
ITBO970107A0 (it) Monobretella.
DZ3205A1 (fr) La pilule stérilisante.
RU97112302A (ru) Репаративное средство для лечения язвенной болезни

Legal Events

Date Code Title Description
KB4A Valid patent at the end of a year

Effective date: 20101231