ECSP982404A - ARILSULFONIL HYDROXAMIC ACID DERIVATIVES - Google Patents
ARILSULFONIL HYDROXAMIC ACID DERIVATIVESInfo
- Publication number
- ECSP982404A ECSP982404A ECSP982404A ECSP982404A EC SP982404 A ECSP982404 A EC SP982404A EC SP982404 A ECSP982404 A EC SP982404A EC SP982404 A ECSP982404 A EC SP982404A
- Authority
- EC
- Ecuador
- Prior art keywords
- treatment
- cancer
- arilsulfonil
- acid derivatives
- hydroxamic acid
- Prior art date
Links
Abstract
El invento se refiere a un compuesto de fórmula en la que R1, R2, R3, R4, R5, R6, R7, R8, R9 y Q son como se han definido anteriormente, útil en el tratamiento de un trastorno seleccionado entre el grupo formado por artritis, cáncer, ulceración del tejido, degeneración muscular, restenosis, enfermedad periodontal, epidermólisis vesicular, escleritis y otras enfermedades caracterizadas por la actividad de metaloproteinasas de la matriz, SIDA, septicemia, choque séptico y otras enfermedades que implican la producción de TNF. Además, los compuestos de la presente invención se pueden usar en tratamiento de combinación con fármacos antiinflamatorios no esteroideos (AINE) y analgésicos convencionales, y en combinación con fármacos citotóxicos como adriamicina, aunomicina, cisplatino, etopósido, taxol, taxótero y otros alcaloides, como vincristina en el tratamiento de cáncer.The invention relates to a compound of the formula in which R1, R2, R3, R4, R5, R6, R7, R8, R9 and Q are as defined above, useful in the treatment of a disorder selected from the group formed for arthritis, cancer, tissue ulceration, muscle degeneration, restenosis, periodontal disease, vesicular epidermolysis, scleritis and other diseases characterized by the activity of matrix metalloproteinases, AIDS, sepsis, septic shock and other diseases that involve the production of TNF. Furthermore, the compounds of the present invention can be used in combination treatment with non-steroidal anti-inflammatory drugs (NSAIDs) and conventional pain relievers, and in combination with cytotoxic drugs such as adriamycin, Aunomycin, cisplatin, etoposide, taxol, taxater and other alkaloids, such as Vincristine in the treatment of cancer.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982404 ECSP982404A (en) | 1998-02-10 | 1998-02-10 | ARILSULFONIL HYDROXAMIC ACID DERIVATIVES |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982404 ECSP982404A (en) | 1998-02-10 | 1998-02-10 | ARILSULFONIL HYDROXAMIC ACID DERIVATIVES |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP982404A true ECSP982404A (en) | 1998-12-29 |
Family
ID=42043327
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP982404 ECSP982404A (en) | 1998-02-10 | 1998-02-10 | ARILSULFONIL HYDROXAMIC ACID DERIVATIVES |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP982404A (en) |
-
1998
- 1998-02-10 EC ECSP982404 patent/ECSP982404A/en unknown
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