ECSP972233A - DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO - Google Patents
DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICOInfo
- Publication number
- ECSP972233A ECSP972233A ECSP972233A ECSP972233A EC SP972233 A ECSP972233 A EC SP972233A EC SP972233 A ECSP972233 A EC SP972233A EC SP972233 A ECSP972233 A EC SP972233A
- Authority
- EC
- Ecuador
- Prior art keywords
- diseases
- involve
- production
- cancer
- hidroxamico
- Prior art date
Links
Abstract
Un compuesto de la fórmula (gráfico), en la que n, X, R1, R1 y Q son como se han definido anteriormente útil en el tratamiento de un trastorno seleccionado entre el grupo formado por artritis, cáncer, ulceración de tejidos, degeneración macular, reestemosis, enfermedad periodontal, epidermólisis ampollosa, esclenitis y otras enfermedades caracterizadas por actividad de metaloproteinasa matriciales, SIDA, sepsis, choque séptico y otras enfermedades que implican la producción de factor de necrosis tumoral enfermedades que implican la producción de factor de neurosis tumoral (TNF). Además, los compuestos de la presente invención se pueden usar en terapia de combinación con fármacos antiinflamatorios no esteroides (AINE) y analgésicos convencionales y junto con fármacos citotóxicos como adriamicina, daunomicina, cisplatino, etopóxido, taxol, taxóteroy otros alcaloides como vineristina, en el tratamiento de cáncer.A compound of the formula (graph), wherein n, X, R1, R1 and Q are as defined above useful in the treatment of a disorder selected from the group consisting of arthritis, cancer, tissue ulceration, macular degeneration , rheosmosis, periodontal disease, epidermolysis bullosa, sclenitis and other diseases characterized by matrix metalloproteinase activity, AIDS, sepsis, septic shock and other diseases that involve the production of tumor necrosis factor, diseases that involve the production of tumor neurosis factor (TNF ). Furthermore, the compounds of the present invention can be used in combination therapy with non-steroidal anti-inflammatory drugs (NSAIDs) and conventional pain relievers, and together with cytotoxic drugs such as adriamycin, daunomycin, cisplatin, etopoxide, taxol, taxatero, and other alkaloids such as vineristine, in the cancer treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972233 ECSP972233A (en) | 1997-08-22 | 1997-08-22 | DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP972233 ECSP972233A (en) | 1997-08-22 | 1997-08-22 | DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP972233A true ECSP972233A (en) | 1998-09-22 |
Family
ID=42043064
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP972233 ECSP972233A (en) | 1997-08-22 | 1997-08-22 | DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP972233A (en) |
-
1997
- 1997-08-22 EC ECSP972233 patent/ECSP972233A/en unknown
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| AR009292A1 (en) | DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO, PROCESSES FOR ITS PREPARATION AND PHARMACEUTICAL COMPOSITIONS THAT CONTAIN IT | |
| AR011056A1 (en) | SULPHONE-DERIVED COMPOUND AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | |
| CO4890852A1 (en) | MATRICIAL METALOPROTEASE INHIBITORS BASED ON PHOSPHYTES | |
| PA8446101A1 (en) | ARILSULFONIL HYDROXAMIC ACID DERIVATIVES | |
| BR9807815A (en) | Arylsulfonylamino-hydroxamic acid derivatives | |
| AR019241A1 (en) | DERIVATIVES OF HYDROXAMIC HYDROXAMIC ACID, COMPOSITIONS THAT CONTAIN THEM AND PROCEDURE OF TREATMENT OF ARTHRITIS, CANCER AND OTHER DISEASES. | |
| ES2178724T3 (en) | ARILSULFONAMIDE ALPHA-SUBSTITUTED HYDROXAMIC ACIDS AS INHIBITORS OF ALFA TUMOR NECROSIS FACTOR AND MATRIX METALOPROTEINASES. | |
| CO4700432A1 (en) | DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXALICO | |
| UY25992A1 (en) | PROCEDURE FOR PREPARING TACE INHIBITORS (TUMOR NECROSIS ALPHA FACTOR CONVERSING ENZYME) | |
| PA8456801A1 (en) | DERIVATIVES OF ARILOXIARILSULFONILAMINO HIDROXAMICOS ACIDS | |
| ES2153031T3 (en) | ARILSULFONIL HYDROXAMIC ACID DERIVATIVES AS INHIBITORS OF MMP AND TNF. | |
| GT200300177A (en) | COMBINATION THERAPY FOR HYPERPROLIFERATIVE DISEASES | |
| ECSP972233A (en) | DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO | |
| ECSP982358A (en) | CYCLE DERIVATIVES OF SULFONA | |
| ECSP982404A (en) | ARILSULFONIL HYDROXAMIC ACID DERIVATIVES | |
| ECSP982394A (en) | ARILSULFONYLAMINOHYDROXAMIC ACID DERIVATIVES | |
| ECSP972193A (en) | PHOSPHINATE BASED MATRIO METALOPROTEASE INHIBITORS | |
| ECSP993100A (en) | HYDROXY ACID DERIVATIVES - HYDROXAMIC PIPECOLATE | |
| ECSP993099A (en) | TACE INHIBITORS | |
| CO4700438A1 (en) | DERIVATIVES OF ARYLSULPHONYL HYDROXAMIC ACIDS WHICH ARE INHIBITORS OF MATRIX METALOPROTEINASES OR THE PRODUCTION OF TUMOR NECROSIS FACTOR | |
| ECSP961719A (en) | DERIVATIVES OF ACID ARIL SULFONIL HIDROXAMICO | |
| ECSP961684A (en) | DERIVATIVES OF ACID ARILSULFONILAMINO HIDROXAMICO | |
| GT199800003A (en) | CYCLE DERIVATIVES OF SULFONA |