ECSP982358A - CYCLE DERIVATIVES OF SULFONA - Google Patents
CYCLE DERIVATIVES OF SULFONAInfo
- Publication number
- ECSP982358A ECSP982358A ECSP982358A ECSP982358A EC SP982358 A ECSP982358 A EC SP982358A EC SP982358 A ECSP982358 A EC SP982358A EC SP982358 A ECSP982358 A EC SP982358A
- Authority
- EC
- Ecuador
- Prior art keywords
- cancer
- treatment
- sulfona
- diseases
- taxometer
- Prior art date
Links
Abstract
Un compuesto de fórmula en la que n, X,Y y Ar son como se definen en la presente, útil en el tratamiento de un trastorno seleccionado entre el grupo formado por artritis, cáncer, ulceración de tejidos, degeneración macular, reestenosis, enfermedad periodontal, epidermólisis ampollosa, escleritis y otras enfermedades caracterizadas por actividad de metaloproteinasas matriciales, SIDA, sepsis, choque séptico y otras enfermedades que implican la producción de TNF. Además, los compuestos de la presente invención se pueden usar en terapia de combinación con fármacos antiinflamatorios no esteroides (AINE) y analgésicos convencionales y junto con fármacos citotóxicos como adriamicina, daunomicina, cisplatino, etopósito, taxol, taxómetro y otros alcaloides, como vincristina en el tratamiento de cáncer.A compound of formula where n, X, Y and Ar are as defined herein, useful in the treatment of a disorder selected from the group consisting of arthritis, cancer, tissue ulceration, macular degeneration, restenosis, periodontal disease , epidermolysis bullosa, scleritis and other diseases characterized by activity of matrix metalloproteinases, AIDS, sepsis, septic shock and other diseases that involve the production of TNF. Furthermore, the compounds of the present invention can be used in combination therapy with non-steroidal anti-inflammatory drugs (NSAIDs) and conventional pain relievers and together with cytotoxic drugs such as adriamycin, daunomycin, cisplatin, etoposit, taxol, taxometer and other alkaloids, such as vincristine in cancer treatment.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982358 ECSP982358A (en) | 1998-01-06 | 1998-01-06 | CYCLE DERIVATIVES OF SULFONA |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ECSP982358 ECSP982358A (en) | 1998-01-06 | 1998-01-06 | CYCLE DERIVATIVES OF SULFONA |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP982358A true ECSP982358A (en) | 1998-12-22 |
Family
ID=42043281
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ECSP982358 ECSP982358A (en) | 1998-01-06 | 1998-01-06 | CYCLE DERIVATIVES OF SULFONA |
Country Status (1)
| Country | Link |
|---|---|
| EC (1) | ECSP982358A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11753416B2 (en) | 2017-06-09 | 2023-09-12 | Novartis Ag | Compounds and compositions for inducing chondrogenesis |
-
1998
- 1998-01-06 EC ECSP982358 patent/ECSP982358A/en unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US11753416B2 (en) | 2017-06-09 | 2023-09-12 | Novartis Ag | Compounds and compositions for inducing chondrogenesis |
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