ECSP088621A - Derivados de triazoloanilinopirimidina para uso como agentes antivirales - Google Patents

Derivados de triazoloanilinopirimidina para uso como agentes antivirales

Info

Publication number
ECSP088621A
ECSP088621A EC2008008621A ECSP088621A ECSP088621A EC SP088621 A ECSP088621 A EC SP088621A EC 2008008621 A EC2008008621 A EC 2008008621A EC SP088621 A ECSP088621 A EC SP088621A EC SP088621 A ECSP088621 A EC SP088621A
Authority
EC
Ecuador
Prior art keywords
triazoloanylinopirimidine
derivatives
antiviral agents
formula
prevention
Prior art date
Application number
EC2008008621A
Other languages
English (en)
Inventor
Neil Mathews
Alexander James Floyd Thomas
Christopher John Pilkington
Keith Charles Spencer
Nathalie Tiberghien
Lyn Jennens
Surinder Chana
Ian John Fraser
Original Assignee
Arrow Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0600510A external-priority patent/GB0600510D0/en
Priority claimed from GB0612116A external-priority patent/GB0612116D0/en
Application filed by Arrow Therapeutics Ltd filed Critical Arrow Therapeutics Ltd
Publication of ECSP088621A publication Critical patent/ECSP088621A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Abstract

Un derivado de quinazolina de fórmula (I), o una sal farmacéuticamente aceptable del mismo: formula (I) para uso en el tratamiento de prevención de una infección por flaviviridae.
EC2008008621A 2006-01-11 2008-07-11 Derivados de triazoloanilinopirimidina para uso como agentes antivirales ECSP088621A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0600510A GB0600510D0 (en) 2006-01-11 2006-01-11 Chemical compounds
GB0612116A GB0612116D0 (en) 2006-06-19 2006-06-19 Chemical Compounds

Publications (1)

Publication Number Publication Date
ECSP088621A true ECSP088621A (es) 2008-08-29

Family

ID=37888130

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2008008621A ECSP088621A (es) 2006-01-11 2008-07-11 Derivados de triazoloanilinopirimidina para uso como agentes antivirales

Country Status (15)

Country Link
US (1) US20100158863A1 (es)
EP (1) EP1981876B1 (es)
JP (1) JP2009523163A (es)
KR (1) KR20080083139A (es)
AT (1) ATE508125T1 (es)
AU (1) AU2007204227B2 (es)
BR (1) BRPI0706412A2 (es)
CA (1) CA2635916A1 (es)
DE (1) DE602007014324D1 (es)
EC (1) ECSP088621A (es)
IL (1) IL191928A0 (es)
NZ (1) NZ569703A (es)
RU (1) RU2008132806A (es)
TW (1) TW200902515A (es)
WO (1) WO2007080401A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7759495B2 (en) 2006-08-11 2010-07-20 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US7745636B2 (en) 2006-08-11 2010-06-29 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US7659270B2 (en) 2006-08-11 2010-02-09 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US8303944B2 (en) 2006-08-11 2012-11-06 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
US8329159B2 (en) 2006-08-11 2012-12-11 Bristol-Myers Squibb Company Hepatitis C virus inhibitors
JP2011511841A (ja) * 2008-02-12 2011-04-14 ブリストル−マイヤーズ スクイブ カンパニー Ｃ型肝炎ウイルス阻害剤
CN102552271B (zh) 2010-12-09 2014-08-06 中国科学院上海药物研究所 一类喹唑啉类化合物在制备抗黄病毒科病毒的药物中的用途

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0912559B1 (en) * 1996-07-13 2002-11-06 Glaxo Group Limited Fused heterocyclic compounds as protein tyrosine kinase inhibitors
WO2000004900A1 (en) * 1998-07-20 2000-02-03 Bristol-Myers Squibb Company Substituted benzimidazole antiviral agents
US20030176454A1 (en) * 2000-05-15 2003-09-18 Akira Yamada N-coating heterocyclic compounds
CL2004000234A1 (es) * 2003-02-12 2005-04-15 Biogen Idec Inc Compuestos derivados 3-(piridin-2-il)-4-heteroaril-pirazol sustituidos, antagonistas de aik5 y/o aik4; composicion farmaceutica y uso del compuesto en el tratamiento de desordenes fibroticos como esclerodermia, lupus nefritico, cicatrizacion de herid
EP1748991A1 (en) * 2004-04-28 2007-02-07 Arrow Therapeutics Limited Morpholinylanilinoquinazo- line derivatives for use as antiviral agents
GB0501964D0 (en) * 2005-01-31 2005-03-09 Arrow Therapeutics Ltd Chemical compounds
US8143288B2 (en) * 2005-06-06 2012-03-27 Bristol-Myers Squibb Company Inhibitors of HCV replication
GB0520475D0 (en) * 2005-10-07 2005-11-16 Arrow Therapeutics Ltd Chemical compounds

Also Published As

Publication number Publication date
DE602007014324D1 (de) 2011-06-16
EP1981876A1 (en) 2008-10-22
CA2635916A1 (en) 2007-07-19
EP1981876B1 (en) 2011-05-04
WO2007080401A1 (en) 2007-07-19
KR20080083139A (ko) 2008-09-16
JP2009523163A (ja) 2009-06-18
BRPI0706412A2 (pt) 2011-03-29
RU2008132806A (ru) 2010-02-20
AU2007204227A1 (en) 2007-07-19
AU2007204227B2 (en) 2011-03-03
TW200902515A (en) 2009-01-16
IL191928A0 (en) 2008-12-29
ATE508125T1 (de) 2011-05-15
US20100158863A1 (en) 2010-06-24
WO2007080401A8 (en) 2008-07-24
NZ569703A (en) 2011-07-29

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