EA202090616A1 - Способы и системы для получения метаболита с использованием обогащенных водородом с1-содержащих субстратов - Google Patents
Способы и системы для получения метаболита с использованием обогащенных водородом с1-содержащих субстратовInfo
- Publication number
- EA202090616A1 EA202090616A1 EA202090616A EA202090616A EA202090616A1 EA 202090616 A1 EA202090616 A1 EA 202090616A1 EA 202090616 A EA202090616 A EA 202090616A EA 202090616 A EA202090616 A EA 202090616A EA 202090616 A1 EA202090616 A1 EA 202090616A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- hydrogen
- gaseous substrate
- inoculation
- containing gaseous
- bioreactor
- Prior art date
Links
- 239000000758 substrate Substances 0.000 title abstract 6
- 229910052739 hydrogen Inorganic materials 0.000 title abstract 4
- 239000001257 hydrogen Substances 0.000 title abstract 4
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical class [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 title abstract 3
- 238000011081 inoculation Methods 0.000 abstract 7
- 238000000855 fermentation Methods 0.000 abstract 3
- 230000004151 fermentation Effects 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 239000002054 inoculum Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P5/00—Preparation of hydrocarbons or halogenated hydrocarbons
- C12P5/02—Preparation of hydrocarbons or halogenated hydrocarbons acyclic
- C12P5/026—Unsaturated compounds, i.e. alkenes, alkynes or allenes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/26—Processes using, or culture media containing, hydrocarbons
- C12N1/28—Processes using, or culture media containing, hydrocarbons aliphatic
- C12N1/30—Processes using, or culture media containing, hydrocarbons aliphatic having five or less carbon atoms
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/065—Ethanol, i.e. non-beverage with microorganisms other than yeasts
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/08—Ethanol, i.e. non-beverage produced as by-product or from waste or cellulosic material substrate
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
- C12P7/14—Multiple stages of fermentation; Multiple types of microorganisms or re-use of microorganisms
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/16—Butanols
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
- C12P7/26—Ketones
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/54—Acetic acid
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
- C12P7/6436—Fatty acid esters
- C12P7/649—Biodiesel, i.e. fatty acid alkyl esters
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/02—Acetobacter
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/145—Clostridium
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Polymers & Plastics (AREA)
- Medicinal Chemistry (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Molecular Biology (AREA)
- Animal Husbandry (AREA)
- Physiology (AREA)
- Food Science & Technology (AREA)
- Sustainable Development (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Carbon And Carbon Compounds (AREA)
Abstract
Изобретение относится к способу получения одного или нескольких продуктов ферментации посредством многостадийного процесса ферментации, включающего в себя инокуляционный реактор и по меньшей мере один биореактор. В инокуляционный реактор инокуляции подают С1-содержащий газообразный субстрат, содержащий уменьшенное количество водорода. Водород восстанавливают для увеличения содержания CO в С1-содержащем газообразном субстрате, подаваемом в инокуляционный реактор. Инокуляционный реактор ферментирует обогащенный CO С1-содержащий газообразный субстрат и производит инокулят, который подают по меньшей мере в один биореактор. Биореактор принимает С1-содержащий газообразный субстрат, который может содержать или не содержать уменьшенные количества водорода, для получения одного или нескольких продуктов ферментации. Благодаря подаче обогащенного CO С1-содержащего газообразного субстрата в инокуляционный реактор как инокуляционный реактор, так и последующий биореактор(ы) могут иметь повышенную стабильность и селективность по продукту.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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US201762556099P | 2017-09-08 | 2017-09-08 | |
PCT/US2018/049723 WO2019051069A1 (en) | 2017-09-08 | 2018-09-06 | METHODS AND SYSTEMS FOR PRODUCING METABOLITES USING SUBSTRATES CONTAINING C1 COMPOUNDS RICH IN HYDROGEN |
Publications (1)
Publication Number | Publication Date |
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EA202090616A1 true EA202090616A1 (ru) | 2020-06-10 |
Family
ID=65630644
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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EA202090616A EA202090616A1 (ru) | 2017-09-08 | 2018-09-06 | Способы и системы для получения метаболита с использованием обогащенных водородом с1-содержащих субстратов |
Country Status (16)
Country | Link |
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US (2) | US10808263B2 (ru) |
EP (1) | EP3679149B1 (ru) |
JP (2) | JP7326252B2 (ru) |
KR (1) | KR20200041381A (ru) |
CN (2) | CN117551705A (ru) |
AU (1) | AU2018329846B2 (ru) |
BR (1) | BR112020004591A2 (ru) |
CA (2) | CA3125247C (ru) |
EA (1) | EA202090616A1 (ru) |
ES (1) | ES2926336T3 (ru) |
MY (1) | MY193827A (ru) |
PT (1) | PT3679149T (ru) |
SG (1) | SG11202001716XA (ru) |
TW (2) | TWI787340B (ru) |
WO (1) | WO2019051069A1 (ru) |
ZA (1) | ZA202001312B (ru) |
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CA2965368C (en) * | 2014-10-22 | 2018-08-14 | Lanzatech New Zealand Limited | Multi-stage bioreactor processes |
JP7348305B2 (ja) * | 2019-07-11 | 2023-09-20 | ランザテク,インコーポレイテッド | ガス利用を最適化するための方法 |
WO2022092338A1 (ko) * | 2020-10-27 | 2022-05-05 | 충남대학교산학협력단 | 유기물질 기반 나노유체에 의한 미생물의 씨원가스를 활용한 대사산물 생산성 향상방법 |
CN117280040A (zh) * | 2021-04-09 | 2023-12-22 | 朗泽科技有限公司 | 控制气体发酵平台以提高二氧化碳转化为产物的方法 |
CN117098850A (zh) * | 2021-04-09 | 2023-11-21 | 朗泽科技有限公司 | 用于提供原料的方法和设备 |
JP2024514490A (ja) * | 2021-04-09 | 2024-04-02 | ランザテク,インコーポレイテッド | 炭素変換率を改善するための方法 |
IT202100020819A1 (it) | 2021-08-02 | 2023-02-02 | Nextchem S P A | Processo ed apparato per la produzione di bioetanolo senza emissioni di co2 mediante conversione di syngas ottenuto dalla conversione termica ad alta temperatura di rifiuti |
AU2022354049A1 (en) * | 2021-10-03 | 2024-04-11 | Lanzatech, Inc. | Gas fermentation conversion of carbon dioxide into products |
US20230357800A1 (en) * | 2022-05-06 | 2023-11-09 | Lanzatech, Inc. | Integration of renewable chemical production into oil, gas, petroleum, and chemical processing and infrastructure |
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CN102866193B (zh) | 2012-09-04 | 2015-04-01 | 吴传勇 | 基于介电泳来操控液体中的粒子的器件及方法 |
EP3017053B1 (en) | 2013-07-04 | 2021-04-07 | Lanzatech New Zealand Limited | Multiple reactor system for continuous gas fermentation |
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CA3151146C (en) | 2015-10-13 | 2024-03-19 | Lanzatech Nz, Inc. | Genetically engineered bacterium comprising energy-generating fermentation pathway |
EP3384005B1 (en) * | 2015-12-03 | 2022-02-02 | LanzaTech NZ, Inc. | Arginine as sole nitrogen source for c1-fixing microorganism |
EP4234708A3 (en) | 2016-02-01 | 2024-03-20 | LanzaTech NZ, Inc. | Integrated fermentation and electrolysis process |
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2018
- 2018-09-06 CN CN202311511904.6A patent/CN117551705A/zh active Pending
- 2018-09-06 AU AU2018329846A patent/AU2018329846B2/en active Active
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US20190078121A1 (en) | 2019-03-14 |
TW201920645A (zh) | 2019-06-01 |
TWI787340B (zh) | 2022-12-21 |
JP7326252B2 (ja) | 2023-08-15 |
US20200399664A1 (en) | 2020-12-24 |
ZA202001312B (en) | 2021-08-25 |
CA3074292C (en) | 2021-08-24 |
CN111051517B (zh) | 2023-10-27 |
TW202311521A (zh) | 2023-03-16 |
CN111051517A (zh) | 2020-04-21 |
PT3679149T (pt) | 2022-09-05 |
EP3679149A1 (en) | 2020-07-15 |
BR112020004591A2 (pt) | 2020-09-08 |
US11466295B2 (en) | 2022-10-11 |
CA3125247C (en) | 2023-08-01 |
SG11202001716XA (en) | 2020-03-30 |
CN117551705A (zh) | 2024-02-13 |
JP2020532990A (ja) | 2020-11-19 |
ES2926336T3 (es) | 2022-10-25 |
MY193827A (en) | 2022-10-27 |
CA3074292A1 (en) | 2019-03-14 |
US10808263B2 (en) | 2020-10-20 |
AU2018329846B2 (en) | 2024-01-11 |
AU2018329846A1 (en) | 2020-03-19 |
EP3679149B1 (en) | 2022-06-29 |
EP3679149A4 (en) | 2021-06-02 |
WO2019051069A1 (en) | 2019-03-14 |
CA3125247A1 (en) | 2019-03-14 |
JP2023145652A (ja) | 2023-10-11 |
KR20200041381A (ko) | 2020-04-21 |
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