EA201891956A1 - Способ ферментации с получением лактата магния - Google Patents

Способ ферментации с получением лактата магния

Info

Publication number
EA201891956A1
EA201891956A1 EA201891956A EA201891956A EA201891956A1 EA 201891956 A1 EA201891956 A1 EA 201891956A1 EA 201891956 A EA201891956 A EA 201891956A EA 201891956 A EA201891956 A EA 201891956A EA 201891956 A1 EA201891956 A1 EA 201891956A1
Authority
EA
Eurasian Patent Office
Prior art keywords
fermentation
magnesium lactate
fermentation broth
solid
carbon source
Prior art date
Application number
EA201891956A
Other languages
English (en)
Inventor
Алиаксей Калбасенка
Ерун Бокхове
Original Assignee
ПУРАК Биокем БВ
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ПУРАК Биокем БВ filed Critical ПУРАК Биокем БВ
Publication of EA201891956A1 publication Critical patent/EA201891956A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/56—Lactic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/02—Preparation of carboxylic acids or their salts, halides or anhydrides from salts of carboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M1/00—Apparatus for enzymology or microbiology
    • C12M1/36—Apparatus for enzymology or microbiology including condition or time responsive control, e.g. automatically controlled fermentors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Настоящее изобретение относится к способу ферментации для производства лактата магния из источника углерода, включающему стадии обеспечения ферментационной среды, содержащей ферментируемый источник углерода, в реакторе для ферментации, ферментации ферментационной среды с помощью микроорганизма, продуцирующего молочную кислоту, в присутствии щелочной соли магния с получением ферментационного бульона, содержащего лактат магния, и извлечения твердого лактата магния из ферментационного бульона, содержащего лактат магния, при этом в течение по меньшей мере 40% рабочего времени процесса ферментации концентрация твердого лактата магния в ферментационном бульоне поддерживается в диапазоне 5-40 об.%, в пересчете на кристаллы твердого лактата магния относительно общей массы ферментационного бульона. Способ по изобретению обеспечивает стабильную работу при высокой производительности, а также эффективное разделение продукта.
EA201891956A 2016-04-12 2017-04-10 Способ ферментации с получением лактата магния EA201891956A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16164820 2016-04-12
PCT/EP2017/058547 WO2017178426A1 (en) 2016-04-12 2017-04-10 Magnesium lactate fermentation process

Publications (1)

Publication Number Publication Date
EA201891956A1 true EA201891956A1 (ru) 2019-04-30

Family

ID=55754126

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201891956A EA201891956A1 (ru) 2016-04-12 2017-04-10 Способ ферментации с получением лактата магния

Country Status (13)

Country Link
US (2) US10920250B2 (ru)
EP (1) EP3443109A1 (ru)
JP (1) JP6797208B2 (ru)
KR (2) KR102309997B1 (ru)
CN (1) CN109072260B (ru)
AU (1) AU2017249385B2 (ru)
BR (1) BR112018070996A2 (ru)
CA (1) CA3019265C (ru)
EA (1) EA201891956A1 (ru)
MY (1) MY192367A (ru)
UA (1) UA125821C2 (ru)
WO (1) WO2017178426A1 (ru)
ZA (1) ZA201806681B (ru)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR112018070996A2 (pt) * 2016-04-12 2019-01-29 Purac Biochem Bv processo de fermentação de lactato de magnésio
WO2020110108A1 (en) 2018-11-26 2020-06-04 3Plw Ltd. Purification of magnesium lactate from fermentation broths having high amounts of impurities
AU2020237077A1 (en) * 2019-03-11 2021-08-26 Ralco Nutrition, Inc. Macronutrient compounds
MX2022010137A (es) * 2020-02-19 2022-11-10 Triplew Ltd Metodos y sistemas para la produccion de acido lactico y el reciclaje del acido polilactico.
CN116829529A (zh) * 2021-01-21 2023-09-29 三W有限公司 高纯度l-乳酸镁的结晶
WO2023126937A1 (en) * 2021-12-29 2023-07-06 B. G. Negev Technologies And Applications Ltd., At Ben-Gurion University Selective separation of ammonium and lactate from cell culture media
JP7341574B1 (ja) 2023-03-23 2023-09-11 加藤化学株式会社 乳酸マグネシウムの製造方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB173479A (en) * 1920-12-27 1922-11-09 Joseph Schatzkes Improved process of purifying lactic acid
ES275159A1 (es) 1962-02-22 1962-05-01 Ayuso Utiel Luis Un proceso industrial de fermentaciën continua de acido lactico
JPS60217897A (ja) * 1984-04-13 1985-10-31 Taki Chem Co Ltd 乳酸の分離精製方法
US6229046B1 (en) * 1997-10-14 2001-05-08 Cargill, Incorported Lactic acid processing methods arrangements and products
CN1316031C (zh) * 2002-05-14 2007-05-16 普拉克生化公司 由淀粉的同时糖化和发酵生产乳酸或其盐的方法
BRPI0512167B1 (pt) * 2004-06-17 2015-11-10 Purac Biochem Bv processo para a preparação de ácido lático ou lactato a partir de um meio que compreende lactato de magnésio
US8431372B2 (en) 2009-06-19 2013-04-30 Mbi International Fermentation method using a magnesium compound containing oxygen
EP2311968A1 (en) * 2009-10-14 2011-04-20 PURAC Biochem BV Fermentation process at reduced pressure
CA2787716C (en) * 2010-02-08 2018-01-02 Purac Biochem Bv Process for manufacturing lactic acid
JP2011172492A (ja) * 2010-02-23 2011-09-08 Toray Ind Inc 乳酸塩の製造方法
EP2604696A1 (en) 2011-12-16 2013-06-19 PURAC Biochem BV Process for the fermentative production of lactic acid from a plant extract in the presence of a caustic magnesium salt
WO2013160352A1 (en) 2012-04-25 2013-10-31 Purac Biochem Bv Fermentation process
CN106536743A (zh) 2014-07-28 2017-03-22 普拉克生化公司 用于制备乳酸的方法
WO2016016234A1 (en) 2014-07-28 2016-02-04 Purac Biochem Bv Method of pre-treatment of lignocellulosic materials
DE102014215089A1 (de) * 2014-07-31 2016-02-04 Ksb Aktiengesellschaft Strömungsführendes Bauteil
CN105018538B (zh) 2015-07-07 2018-10-23 北京化工大学 一种基于结晶法发酵分离耦合生产乳酸镁的方法
BR112018070996A2 (pt) * 2016-04-12 2019-01-29 Purac Biochem Bv processo de fermentação de lactato de magnésio

Also Published As

Publication number Publication date
US20190024125A1 (en) 2019-01-24
KR102309997B1 (ko) 2021-10-12
CA3019265A1 (en) 2017-10-19
MY192367A (en) 2022-08-17
AU2017249385A1 (en) 2018-10-25
ZA201806681B (en) 2019-07-31
UA125821C2 (uk) 2022-06-15
AU2017249385B2 (en) 2020-01-23
US10920250B2 (en) 2021-02-16
US11661614B2 (en) 2023-05-30
EP3443109A1 (en) 2019-02-20
CN109072260A (zh) 2018-12-21
KR20180132864A (ko) 2018-12-12
BR112018070996A2 (pt) 2019-01-29
JP6797208B2 (ja) 2020-12-09
US20210130856A1 (en) 2021-05-06
KR20200136490A (ko) 2020-12-07
CN109072260B (zh) 2022-06-14
WO2017178426A1 (en) 2017-10-19
CA3019265C (en) 2022-03-08
JP2019513379A (ja) 2019-05-30

Similar Documents

Publication Publication Date Title
EA201891956A1 (ru) Способ ферментации с получением лактата магния
MY156760A (en) Process for manufacturing succinic acid
WO2013102084A3 (en) Fermentative production of alcohols
MY170936A (en) Process for producing 2,3-butanediol
CO2018011096A2 (es) Procedimiento para la producción de ácido láctico
BR112016021406A2 (pt) Processo de produção de ácido orgânico por fermentação e micro-organismo modificado
Wang et al. High-level production of calcium malate from glucose by Penicillium sclerotiorum K302
MY173237A (en) Process for the fermentative production of lactic acid from a plant extract in the presence of a caustic magnesium salt
Gausmann et al. Electrochemical pH-T-swing separation of itaconic acid for zero salt waste downstream processing
RU2013109055A (ru) Новый продуцирующий янтарную кислоту мутантный микроорганизм, который одновременно использует сахарозу и глицерин, и способ получения янтарной кислоты с его применением
JP6524114B2 (ja) アウレオバシジウム プルランス（ａｕｒｅｏｂａｓｉｄｉｕｍ ｐｕｌｌｕｌａｎｓ）の株からラクトンを生成する方法
Patel et al. Production of acetic acid from molasses by fermentation process
RU2017101543A (ru) Новый способ извлечения молочной кислоты
WO2017003387A3 (en) Process for producing lactic acid or its salts from fermentation using thermotolerance bacillus bacteria
CN109709334B (zh) 一种分析油料粕中矿物质在芽孢杆菌发酵生产伊枯草菌素a中作用的方法
MY194236A (en) Yeast strain having improved capability for fermenting xylose in the presence of acetic acid
CN102925368B (zh) 一种可催化不对称还原反应的球孢白僵菌及其应用
MX2016015894A (es) Procedimiento de fermentacion a base de glicerol.
EA201992758A1 (ru) Способы ферментации метана с высокой производительностью
PL412983A1 (pl) Sposób wytwarzania naturalnego 2-fenyloetanolu
KR101745079B1 (ko) 아세테이트 첨가를 통한 2,3-부탄다이올 생산 방법
MY200560A (en) Process for producing an organic compound
RU2677311C1 (ru) Способ получения биомассы микроорганизмов
Derunets et al. Optimization of nutrient medium composition for lactic acid microbiological synthesis by bacteria Lactobacillus paracasei
TH138878A (th) การเพิ่มผลผลิตเมธิโอนีน