EA201370071A1 - Способы и композиции для лечения рака легких - Google Patents

Способы и композиции для лечения рака легких

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Publication number
EA201370071A1
EA201370071A1 EA201370071A EA201370071A EA201370071A1 EA 201370071 A1 EA201370071 A1 EA 201370071A1 EA 201370071 A EA201370071 A EA 201370071A EA 201370071 A EA201370071 A EA 201370071A EA 201370071 A1 EA201370071 A1 EA 201370071A1
Authority
EA
Eurasian Patent Office
Prior art keywords
compositions
lung cancer
methods
treatment
provides methods
Prior art date
Application number
EA201370071A
Other languages
English (en)
Inventor
Шэн-Юн Лю
Сань-Бао Хван
Ву-че Вэнь
Original Assignee
Голден Биотекнолоджи Корпорейшн
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Голден Биотекнолоджи Корпорейшн filed Critical Голден Биотекнолоджи Корпорейшн
Publication of EA201370071A1 publication Critical patent/EA201370071A1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/22—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/02—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains containing only carbon and hydrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/08—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/06—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms
    • C07C403/10—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by singly-bound oxygen atoms by etherified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone
    • C07C403/20—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone having side-chains substituted by carboxyl groups or halides, anhydrides, or (thio)esters thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/385—Saturated compounds containing a keto group being part of a ring
    • C07C49/517—Saturated compounds containing a keto group being part of a ring containing ether groups, groups, groups, or groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/16—Systems containing only non-condensed rings with a six-membered ring the ring being unsaturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Изобретение предусматривает способы и композиции для лечения рака легких с помощью соединений циклогексенона.
EA201370071A 2010-09-20 2011-04-15 Способы и композиции для лечения рака легких EA201370071A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
TW99131844 2010-09-20
TW99145853 2010-12-24
US13/070,308 US8309611B2 (en) 2010-09-20 2011-03-23 Methods and compositions for treating lung cancer
PCT/US2011/032785 WO2012039793A1 (en) 2010-09-20 2011-04-15 Methods and compositions for treating lung cancer

Publications (1)

Publication Number Publication Date
EA201370071A1 true EA201370071A1 (ru) 2013-10-30

Family

ID=45818282

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201370071A EA201370071A1 (ru) 2010-09-20 2011-04-15 Способы и композиции для лечения рака легких

Country Status (18)

Country Link
US (1) US8309611B2 (ru)
EP (1) EP2655309A4 (ru)
JP (1) JP2014504256A (ru)
KR (2) KR20130061746A (ru)
CN (1) CN103221373A (ru)
AR (1) AR083026A1 (ru)
AU (1) AU2011306068B2 (ru)
BR (1) BR112013006567A2 (ru)
CA (1) CA2809762C (ru)
CO (1) CO6700836A2 (ru)
EA (1) EA201370071A1 (ru)
IL (1) IL225262A0 (ru)
MA (1) MA34598B1 (ru)
MX (1) MX2011007763A (ru)
MY (1) MY157341A (ru)
SG (1) SG188610A1 (ru)
TW (1) TWI483718B (ru)
WO (1) WO2012039793A1 (ru)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
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US8309611B2 (en) 2010-09-20 2012-11-13 Golden Biotechnology Corporation Methods and compositions for treating lung cancer
CN103570531A (zh) * 2012-07-25 2014-02-12 丽丰实业股份有限公司 樟芝菌丝体的化合物及其用途
CN104968339B (zh) 2012-11-21 2019-06-11 国鼎生物科技股份有限公司 用于治疗神经变性疾病的方法和组合物
TWI597061B (zh) * 2013-02-20 2017-09-01 國鼎生物科技股份有限公司 治療白血病之方法及組成物
US20140274979A1 (en) * 2013-03-13 2014-09-18 Golden Biotechnology Corporation Method for the treatment of fatty liver disease
TWI583376B (zh) * 2013-03-20 2017-05-21 Hui-Ling Zeng Compounds isolated from Antelroxicus and their use
JP5908002B2 (ja) * 2013-03-20 2016-04-26 卉菱 曽 ベニクスノキタケに含まれる化合物及びその用途
US9480723B2 (en) * 2013-05-02 2016-11-01 Kingland Property Corporation, Ltd. Method of preparing an extract of Antrodia cinnamomea having an elevated antcin C and zhankuic C content
CN104211627A (zh) * 2013-05-29 2014-12-17 曾卉菱 牛樟芝化合物、萃取物及其用途
CN104706682B (zh) * 2013-12-12 2018-01-30 富裔实业股份有限公司 一种中草药萃取物及其用于制备肺癌药物的用途
CN105237365B (zh) * 2014-07-09 2017-09-08 台湾利得生物科技股份有限公司 樟芝固态培养菌丝体的萃取物及其应用
WO2016011130A1 (en) * 2014-07-17 2016-01-21 National Taiwan University Compositions and methods for the preparation of 4-oxy-2-cyclohexenone and 6-oxy-2-cyclohexenone compounds
JP6593856B2 (ja) * 2014-09-03 2019-10-23 台灣利得生物科技股▲ふん▼有限公司 抗肺癌細胞転移用組成物およびその製造方法
PL3240772T3 (pl) * 2014-12-30 2021-06-28 ONENESS BIOTECH CO., Ltd Związki z antrodia camphorata, sposoby ich otrzymywania i ich zastosowanie
KR102359784B1 (ko) * 2016-05-13 2022-02-09 골든 바이오테크놀러지 코포레이션 진행 단계 비소세포 폐암을 치료하기 위한 방법 및 조성물

Family Cites Families (15)

* Cited by examiner, † Cited by third party
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JP4861560B2 (ja) * 2001-02-19 2012-01-25 株式会社明治 糖尿病合併症治療剤
US20070116787A1 (en) * 2005-11-21 2007-05-24 Chih-Jung Yao Cancer treatment
TW200829234A (en) * 2007-01-08 2008-07-16 Golden Biotechnology Corp Antrodia camphorata isophorone extract
CN101225066B (zh) 2007-01-18 2010-09-22 国鼎生物科技股份有限公司 牛樟芝的环己烯酮萃取物
TW200918498A (en) 2007-10-19 2009-05-01 Golden Biotechnology Corp Novel compound isolated from Antrodia camphorate extracts
CN101417934B (zh) * 2007-10-24 2012-04-18 国鼎生物科技股份有限公司 分离自牛樟芝萃取物的化合物
TW201102075A (en) * 2009-07-09 2011-01-16 Golden Biotechnology Corp Cyclohexenone compound of Antrodia cinnomomea that suppresses growth of tumor cell of pancreatic cancer
TW201109023A (en) * 2009-09-09 2011-03-16 Golden Biotechnology Corp Cyclohexenone compound of Antrodia cinnomomea that suppresses growth of tumor cell of colorectal cancer
TWI383790B (zh) * 2009-09-09 2013-02-01 Golden Biotechnology Corp Used to inhibit the growth of oral cancer cells of the cattle Antrodylcyclohexenone compounds
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TWI383791B (zh) * 2009-09-09 2013-02-01 Golden Biotechnology Corp Used to inhibit the growth of gastric cancer tumor cells of the male antler ketone compounds
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TWI394566B (zh) * 2009-09-09 2013-05-01 Golden Biotechnology Corp Used to inhibit the growth of ovarian cancer tumor cells of the cattle camphor cyclohexene ketone compounds
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Also Published As

Publication number Publication date
WO2012039793A1 (en) 2012-03-29
AU2011306068B2 (en) 2014-08-07
US8309611B2 (en) 2012-11-13
MA34598B1 (fr) 2013-10-02
US20120071426A1 (en) 2012-03-22
IL225262A0 (en) 2013-06-27
EP2655309A1 (en) 2013-10-30
JP2014504256A (ja) 2014-02-20
TWI483718B (zh) 2015-05-11
MX2011007763A (es) 2012-07-04
EP2655309A4 (en) 2014-09-03
TW201212906A (en) 2012-04-01
KR20130061746A (ko) 2013-06-11
SG188610A1 (en) 2013-04-30
KR20150014534A (ko) 2015-02-06
BR112013006567A2 (pt) 2017-10-24
CO6700836A2 (es) 2013-06-28
CA2809762C (en) 2016-02-02
AU2011306068A1 (en) 2013-05-02
MY157341A (en) 2016-05-31
AR083026A1 (es) 2013-01-23
CA2809762A1 (en) 2012-03-29
CN103221373A (zh) 2013-07-24

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