EA201200999A1 - Способы лечения рака молочной железы - Google Patents

Способы лечения рака молочной железы

Info

Publication number
EA201200999A1
EA201200999A1 EA201200999A EA201200999A EA201200999A1 EA 201200999 A1 EA201200999 A1 EA 201200999A1 EA 201200999 A EA201200999 A EA 201200999A EA 201200999 A EA201200999 A EA 201200999A EA 201200999 A1 EA201200999 A1 EA 201200999A1
Authority
EA
Eurasian Patent Office
Prior art keywords
breast cancer
methods
treatment breast
treatment
progastrin
Prior art date
Application number
EA201200999A
Other languages
English (en)
Other versions
EA025329B1 (ru
Inventor
Жан-Франсуа Флош
Лейла Уу
Франсуа Келлер
Доминик Жубер
Фредерик Олланд
Original Assignee
Биориалите
Инститю Насьональ Де-Ла-Санте Эт Де-Ла-Решерш Медикаль (Инсерм)
Сантр Насьональ Де-Ла Решерш Сьентифик (Снрс)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Биориалите, Инститю Насьональ Де-Ла-Санте Эт Де-Ла-Решерш Медикаль (Инсерм), Сантр Насьональ Де-Ла Решерш Сьентифик (Снрс) filed Critical Биориалите
Publication of EA201200999A1 publication Critical patent/EA201200999A1/ru
Publication of EA025329B1 publication Critical patent/EA025329B1/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/303—Liver or Pancreas
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57438—Specifically defined cancers of liver, pancreas or kidney
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/575—Hormones
    • G01N2333/595—Gastrins; Cholecystokinins [CCK]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Abstract

Настоящее описание относится к способам лечения и профилактики рака молочной железы или рецидива рака молочной железы с помощью композиций, содержащих антитела к прогастрину.
EA201200999A 2010-01-08 2011-01-07 Способы профилактики или предотвращения рецидивов или лечения рака молочной железы EA025329B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29361210P 2010-01-08 2010-01-08
PCT/EP2011/000048 WO2011083090A2 (en) 2010-01-08 2011-01-07 Methods for treating breast cancer

Publications (2)

Publication Number Publication Date
EA201200999A1 true EA201200999A1 (ru) 2013-02-28
EA025329B1 EA025329B1 (ru) 2016-12-30

Family

ID=43607948

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201200999A EA025329B1 (ru) 2010-01-08 2011-01-07 Способы профилактики или предотвращения рецидивов или лечения рака молочной железы
EA201200998A EA023722B1 (ru) 2010-01-08 2011-01-07 ПРИМЕНЕНИЕ АНТИТЕЛА К ЧЕЛОВЕЧЕСКОМУ ПРОГАСТРИНУ (hPG) ДЛЯ ЛЕЧЕНИЯ РАКА ПОДЖЕЛУДОЧНОЙ ЖЕЛЕЗЫ

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201200998A EA023722B1 (ru) 2010-01-08 2011-01-07 ПРИМЕНЕНИЕ АНТИТЕЛА К ЧЕЛОВЕЧЕСКОМУ ПРОГАСТРИНУ (hPG) ДЛЯ ЛЕЧЕНИЯ РАКА ПОДЖЕЛУДОЧНОЙ ЖЕЛЕЗЫ

Country Status (15)

Country Link
US (2) US8900588B2 (ru)
EP (2) EP2542583B8 (ru)
JP (2) JP5572718B2 (ru)
KR (2) KR101468397B1 (ru)
CN (2) CN102933603B (ru)
AU (2) AU2011204653B2 (ru)
BR (2) BR112012016820A2 (ru)
CA (2) CA2786479C (ru)
EA (2) EA025329B1 (ru)
ES (2) ES2657245T3 (ru)
NZ (2) NZ601591A (ru)
PL (2) PL2542583T3 (ru)
SG (2) SG182331A1 (ru)
WO (2) WO2011083091A2 (ru)
ZA (2) ZA201205003B (ru)

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WO2008076454A1 (en) 2006-12-19 2008-06-26 The Board Of Regents Of The University Of Texas System Immunogenic compositions comprising progastrin and uses thereof
CA2806157C (en) * 2010-07-26 2016-11-22 Les Laboratoires Servier Methods and compositions for liver cancer therapy
CA2996205A1 (en) 2015-09-20 2017-03-23 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Monoclonal antibodies specific for fibroblast growth factor receptor 4 (fgfr4) and methods of their use
ES2861587T3 (es) * 2015-12-31 2021-10-06 Progastrine Et Cancers S A R L Composiciones y métodos para detectar y tratar el cáncer de esófago
JP6909795B2 (ja) * 2015-12-31 2021-07-28 プロガストリン、エ、カンセル、エス、アー エル、エルＰｒｏｇａｓｔｒｉｎｅ Ｅｔ Ｃａｎｃｅｒｓ Ｓ．Ａ Ｒ．Ｌ． 胃癌の検出および治療のための組成物および方法
EP3397965A1 (en) * 2015-12-31 2018-11-07 Syncerus S.à R.l. Compositions and methods for assessing the risk of cancer occurrence
EP3954999A1 (en) * 2015-12-31 2022-02-16 Progastrine et Cancers S.à r.l. Compositions and methods for detecting and treating ovarian cancer
JP6831135B2 (ja) * 2017-01-06 2021-02-17 レモネックス インコーポレイテッドＬｅｍｏｎｅｘ Ｉｎｃ． 転移性卵巣癌、子宮内膜癌もしくは乳癌の予防または治療用組成物
JP7071994B2 (ja) 2017-03-30 2022-05-19 プロガストリン、エ、カンセル、エス、アー エル、エル 前立腺がんを治療するための組成物および方法
CN110678753B (zh) * 2017-03-30 2023-10-24 普莱戈斯瑞恩癌症有限责任公司 用于治疗肺癌的组合物和方法
US11267881B2 (en) 2017-09-14 2022-03-08 Charles ROSSER Compositions and methods for treatment of diseases involving CXCL1 function
PT3720879T (pt) * 2017-12-05 2022-07-13 Progastrine Et Cancers S A R L Terapia de combinação entre anticorpo anti-progastrina e imunoterapia para tratar o cancro
AU2018381046A1 (en) 2017-12-08 2020-07-16 Ecs-Biotracker Sàrl Radiolabeled progastrin in cancer diagnosis
WO2019145537A1 (en) 2018-01-26 2019-08-01 Ecs-Progastrin Sa Combination of progastrin detection with other cancer biomarkers in cancer diagnosis
WO2019166499A1 (en) 2018-02-27 2019-09-06 Ecs-Progastrin Sa Progastrin as a biomarker for immunotherapy
CN115925952A (zh) * 2018-03-13 2023-04-07 东莞凡恩世生物医药有限公司 抗叶酸受体1抗体及其用途
CN108864255B (zh) * 2018-06-21 2022-01-04 天津医科大学肿瘤医院 一种乳腺癌干细胞特异性结合多肽及其在制备治疗乳腺癌药物中的应用
WO2020160022A1 (en) * 2019-01-28 2020-08-06 Rosser Charles J Compositions and methods for treatment of diseases involving cxcl1 function

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Also Published As

Publication number Publication date
EA025329B1 (ru) 2016-12-30
EA201200998A1 (ru) 2013-02-28
US20110177062A1 (en) 2011-07-21
CA2786479C (en) 2016-03-15
KR20120135401A (ko) 2012-12-13
NZ601591A (en) 2015-01-30
JP6134141B2 (ja) 2017-05-24
WO2011083091A2 (en) 2011-07-14
AU2011204653A1 (en) 2012-07-26
US20110171213A1 (en) 2011-07-14
EP2542584A2 (en) 2013-01-09
CN102892784B (zh) 2016-06-22
JP2013516439A (ja) 2013-05-13
US8900588B2 (en) 2014-12-02
ZA201205003B (en) 2013-09-25
SG182334A1 (en) 2012-08-30
KR101468397B1 (ko) 2014-12-04
CN102933603A (zh) 2013-02-13
CA2786435C (en) 2017-01-17
KR101438362B1 (ko) 2014-09-05
US9487582B2 (en) 2016-11-08
EP2542583A2 (en) 2013-01-09
CN102892784A (zh) 2013-01-23
AU2011204653B2 (en) 2014-04-10
ZA201205004B (en) 2013-09-25
SG182331A1 (en) 2012-08-30
PL2542584T3 (pl) 2018-04-30
JP2013516438A (ja) 2013-05-13
BR112012016742A2 (pt) 2018-05-15
KR20130028050A (ko) 2013-03-18
ES2657245T3 (es) 2018-03-02
EA023722B1 (ru) 2016-07-29
NZ601588A (en) 2014-07-25
AU2011204654A1 (en) 2012-07-26
BR112012016820A2 (pt) 2023-11-28
EP2542584B1 (en) 2017-10-25
CA2786479A1 (en) 2011-07-14
WO2011083091A3 (en) 2011-09-09
JP5572718B2 (ja) 2014-08-13
WO2011083090A3 (en) 2011-10-06
EP2542584B8 (en) 2017-12-13
WO2011083090A2 (en) 2011-07-14
EP2542583B8 (en) 2017-12-13
EP2542583B1 (en) 2017-10-25
WO2011083091A8 (en) 2012-08-09
CA2786435A1 (en) 2011-07-14
CN102933603B (zh) 2016-01-20
PL2542583T3 (pl) 2018-04-30
ES2657246T3 (es) 2018-03-02
AU2011204654B2 (en) 2014-04-10

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MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM