EA201300609A1 - Композиция для лечения и профилактики заболеваний слизистой оболочки - Google Patents
Композиция для лечения и профилактики заболеваний слизистой оболочкиInfo
- Publication number
- EA201300609A1 EA201300609A1 EA201300609A EA201300609A EA201300609A1 EA 201300609 A1 EA201300609 A1 EA 201300609A1 EA 201300609 A EA201300609 A EA 201300609A EA 201300609 A EA201300609 A EA 201300609A EA 201300609 A1 EA201300609 A1 EA 201300609A1
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- diseases
- treatment
- composition
- prevention
- disorders
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 5
- 201000010099 disease Diseases 0.000 title abstract 4
- 230000002265 prevention Effects 0.000 title abstract 2
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 2
- 208000035475 disorder Diseases 0.000 abstract 2
- 229920002674 hyaluronan Polymers 0.000 abstract 2
- 229960003160 hyaluronic acid Drugs 0.000 abstract 2
- 210000004400 mucous membrane Anatomy 0.000 abstract 2
- 210000001519 tissue Anatomy 0.000 abstract 2
- 206010010741 Conjunctivitis Diseases 0.000 abstract 1
- 208000004232 Enteritis Diseases 0.000 abstract 1
- 208000007882 Gastritis Diseases 0.000 abstract 1
- 208000022559 Inflammatory bowel disease Diseases 0.000 abstract 1
- 206010030216 Oesophagitis Diseases 0.000 abstract 1
- 208000007117 Oral Ulcer Diseases 0.000 abstract 1
- 208000005141 Otitis Diseases 0.000 abstract 1
- 208000008469 Peptic Ulcer Diseases 0.000 abstract 1
- 206010039085 Rhinitis allergic Diseases 0.000 abstract 1
- 206010046914 Vaginal infection Diseases 0.000 abstract 1
- 201000008100 Vaginitis Diseases 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 201000010105 allergic rhinitis Diseases 0.000 abstract 1
- 208000002399 aphthous stomatitis Diseases 0.000 abstract 1
- 206010006451 bronchitis Diseases 0.000 abstract 1
- 201000003146 cystitis Diseases 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 208000019258 ear infection Diseases 0.000 abstract 1
- 208000006881 esophagitis Diseases 0.000 abstract 1
- 208000007565 gingivitis Diseases 0.000 abstract 1
- 208000002551 irritable bowel syndrome Diseases 0.000 abstract 1
- 208000011906 peptic ulcer disease Diseases 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 208000000143 urethritis Diseases 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
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- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/10—Laxatives
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- A61P1/12—Antidiarrhoeals
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
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- A—HUMAN NECESSITIES
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- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Pulmonology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Gynecology & Obstetrics (AREA)
- Otolaryngology (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Предложена композиция разновидностей гиалуроновой кислоты для использования при лечении или профилактике расстройств или заболеваний слизистой оболочки. Композиция содержит смесь разных видов гиалуроновой кислоты, различающихся средним значением молекулярной массы, а также различными реологическими свойствами, изолирующими свойствами, способностью образовывать каркас ткани, а также характеристиками разложения. Получающаяся композиция демонстрирует оптимальный баланс между адгезионными свойствами, способностью образовывать каркас ткани и продолжительностью лечения при лечении или профилактике таких расстройств и заболеваний слизистой оболочки, как конъюнктивит, отит, аллергический ринит, гингивит, язва ротовой полости, бронхит, гастроэзофагиальнорефлюксная болезнь, эзофагит, гастрит, энтерит, пептическая язва, воспалительное заболевание кишечника, синдром раздраженного кишечника, уретрит, цистит и вагинит.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP11173628.6A EP2545925B1 (en) | 2011-07-12 | 2011-07-12 | Compositions comprising hyaluronic acid for treating and preventing mucosa related diseases |
| PCT/US2012/045259 WO2013009519A2 (en) | 2011-07-12 | 2012-07-02 | Materials for treating and preventing mucosa related disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| EA201300609A1 true EA201300609A1 (ru) | 2014-06-30 |
| EA029940B1 EA029940B1 (ru) | 2018-06-29 |
Family
ID=45406907
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EA201300609A EA029940B1 (ru) | 2011-07-12 | 2012-07-02 | Применение композиции для лечения и профилактики заболевания слизистой оболочки дыхательных путей |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US20140010847A1 (ru) |
| EP (1) | EP2545925B1 (ru) |
| JP (1) | JP2014523435A (ru) |
| KR (1) | KR20130099193A (ru) |
| CN (1) | CN103702671A (ru) |
| AU (1) | AU2012283037A1 (ru) |
| BR (1) | BR112013020809A2 (ru) |
| CA (1) | CA2823786C (ru) |
| EA (1) | EA029940B1 (ru) |
| ES (1) | ES2665254T3 (ru) |
| WO (1) | WO2013009519A2 (ru) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101412776B1 (ko) * | 2013-03-11 | 2014-07-01 | 가톨릭대학교 산학협력단 | 각결막염 치료용 점안제 조성물 및 이의 제조 방법 |
| US9572832B2 (en) * | 2013-08-29 | 2017-02-21 | Holy Stone Healthcare Co., Ltd. | Compound of glycosaminoglycan and its fabrication method as well as application |
| KR102237601B1 (ko) | 2013-10-31 | 2021-04-08 | 삼성전자주식회사 | 자석 매립형 모터 및 자석 매립형 모터를 가지는 압축기 |
| EP2985019B1 (en) | 2014-08-16 | 2021-10-20 | Church & Dwight Co., Inc. | Nasal composition having anti-viral properties |
| EP2985027B1 (en) | 2014-08-16 | 2021-03-31 | Church & Dwight Co., Inc. | Nasal composition comprising mixture of hyaluronic acids and saline solution |
| CN104606224A (zh) * | 2015-01-13 | 2015-05-13 | 河北柯瑞生物医药有限公司 | 一种清洗液及其制备方法 |
| WO2016120684A1 (en) * | 2015-01-27 | 2016-08-04 | Apharm S.R.L. | Combination of hyaluronic acid and macrogol and pharmaceutical compositions containing it |
| KR101911377B1 (ko) * | 2016-12-01 | 2018-10-25 | 주식회사 진켐 | 항염 조성물 |
| IT201700057635A1 (it) * | 2017-05-26 | 2018-11-26 | Drugs Minerals And Generics Italia S R L In Forma Abbreviata D M G Italia S R L | Composizione per uso nel trattamento dei sintomi extra-esofagei del reflusso gastrico |
| GB201713362D0 (en) * | 2017-08-21 | 2017-10-04 | Givaudan Sa | Improvements in or relating to organic compounds |
| US10857020B2 (en) | 2017-09-14 | 2020-12-08 | Olympus Corporation | Gastrointestinal track constricting method |
| US10555801B2 (en) | 2018-03-05 | 2020-02-11 | Olympus Corporation | Gastrointestinal-tract constricting method |
| US10561489B2 (en) | 2018-03-05 | 2020-02-18 | Olympus Corporation | Gastrointestinal-tract constricting method |
| US10918454B2 (en) * | 2018-04-02 | 2021-02-16 | Olympus Corporation | Gastrointestinal tract constricting method |
| JP2021521280A (ja) * | 2018-04-12 | 2021-08-26 | マトルクス セラピューティクス コーポレーション | 弾性線維分解を治療するための組成物及び方法 |
| KR102188593B1 (ko) * | 2019-04-03 | 2020-12-09 | 서울대학교산학협력단 | 두 가지의 상이한 분자량의 히알루론산을 포함하는 인공타액 |
| IT201900024958A1 (it) * | 2019-12-20 | 2021-06-20 | Neilos S R L | Composizione per la protezione della mucosa gastro-intestinale e per la prevenzione e il trattamento di patologie ad essa associate |
| KR102501175B1 (ko) * | 2020-02-03 | 2023-02-16 | 엠앤에이치바이오 주식회사 | 난청 치료용 제어 방출형 제제 및 이의 제조방법 |
| IT202000003092A1 (it) * | 2020-02-17 | 2021-08-17 | Neilos S R L | Composizione per la protezione della mucosa gastro-intestinale e per la prevenzione e il trattamento di patologie ad essa associate |
| IT202100002531A1 (it) * | 2021-02-04 | 2022-08-04 | Biofficina Srls | Bevanda funzionale antiossidante ed antinfiammatoria |
| WO2022170405A1 (pt) * | 2021-02-12 | 2022-08-18 | Master Indústria E Comércio De Produtos Odontológicos E Farmacêuticos Ltda Me | Composição farmacêutica de hialuronato de sódio aquosa em forma de spray nasal |
| CN116059241A (zh) * | 2021-11-04 | 2023-05-05 | 华熙生物科技股份有限公司 | 提高机体免疫力、促进胃肠道健康的含透明质酸或其盐的组合物及其应用 |
| CN116114882A (zh) * | 2022-09-19 | 2023-05-16 | 张司晨 | 一种促进消化道黏膜修复的组合物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1229075B (it) | 1985-04-05 | 1991-07-17 | Fidia Farmaceutici | Medicamenti per uso topico, ottenuti tramite l'impiego dell'acido ialuronico |
| CA1291123C (en) | 1986-03-14 | 1991-10-22 | Abraham Nimrod | Heavy metal salts of hyaluronic acid useful as antimicrobial agents |
| US5492936A (en) | 1990-11-30 | 1996-02-20 | Allergan, Inc. | Bimodal molecular weight hyaluronate formulations and methods for using same |
| IN181358B (ru) | 1995-02-14 | 1998-05-30 | Bioniche Inc | |
| IT1281876B1 (it) * | 1995-05-10 | 1998-03-03 | Fidia Advanced Biopolymers Srl | Acido ialuronico e suoi derivati esterei per la preparazione di matrici per il rilascio controllato di farmaci. |
| CA2154103C (en) * | 1995-07-18 | 1998-02-24 | Samuel Simon Asculai | Treatment of mucous membrane disease, trauma or condition and for the relief of pain |
| DE60034667T2 (de) * | 1999-02-01 | 2008-03-13 | Dermal Research Laboratories, Inc. | Pharmazeutische zusammensetzung aus komplexen kohlenhydraten und deren anwendung |
| JP2003089647A (ja) * | 1999-03-10 | 2003-03-28 | Takada Seiyaku Kk | 関節性疾患治療剤 |
| EP1292314A2 (en) * | 2000-05-23 | 2003-03-19 | The Trustees of Columbia University in the City of New York | Method for treating respiratory disorders associated with pulmonary elastic fiber injury comprising the use of glycosaminoglycans |
| ATE417617T1 (de) | 2001-03-15 | 2009-01-15 | Seikagaku Kogyo Co Ltd | Mittel zur steurung der expression von il-12 |
| US20030171332A1 (en) | 2001-05-23 | 2003-09-11 | Abraham William M. | Treatment of respiratory conditions associated with bronchoconstriction with aerosolized hyaluronic acid |
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| DE10240635A1 (de) | 2002-09-03 | 2004-03-11 | Arvinmeritor Gmbh | Führungsmechanik für einen Deckel eines Schiebehebedachs |
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| CN1314361C (zh) * | 2003-04-02 | 2007-05-09 | 李安虎 | 一种关节保健饮品或食品及其制备方法 |
| DK1677806T3 (da) | 2003-10-09 | 2009-02-23 | Robert John Petrella | Sammensætninger til behandling af akut og overbelastningsforårsaget forstuvning og forstrækning ved anvendelse af hyaluronsyre |
| DE10356248A1 (de) | 2003-11-13 | 2005-06-23 | Maria Clementine Martin Klosterfrau Vertriebsgesellschaft Mbh | Pharmazeutische Zusammensetzung zur Behandlung von Rhinitiden |
| US7879818B2 (en) | 2005-12-23 | 2011-02-01 | Janos Borbely | Hyaluronic acid-based cross-linked nanoparticles |
| WO2007131546A1 (en) * | 2006-05-11 | 2007-11-22 | Sandra Gobbo | Hyaluronic acid binary mixtures and therapeutic use thereof |
| KR100927579B1 (ko) | 2006-12-13 | 2009-11-23 | 주식회사 엘지생명과학 | 히아루론산 및/또는 그것의 염을 함유하는 아토피성피부염의 개선 및 치료를 위한 조성물 |
| US9597277B2 (en) * | 2006-12-22 | 2017-03-21 | Croma-Pharma Gesellschaft M.B.H. | Use of polymers |
| KR20080074583A (ko) * | 2007-02-09 | 2008-08-13 | 주식회사 핸슨바이오텍 | 히알루론산으로 이루어지는 알러지 질환 예방 및 치료용약제, 식품 및 화장품 |
| IT1396468B1 (it) | 2008-11-11 | 2012-12-14 | Farma Derma Srl | Uso topico di acido ialuronico ad azione filmogena in preparati per il trattamento e profilassi di patologie delle vie respiratorie. |
| TWI516269B (zh) * | 2009-08-14 | 2016-01-11 | 禾伸堂生技股份有限公司 | 使用於炎症性腸疾病（ｉｂｄ）治療和預防之透明質酸混合物 |
| TWI383796B (zh) * | 2009-08-14 | 2013-02-01 | Holy Stone Healthcare Co Ltd | Use of hyaluronic acid mixture for the treatment and prevention of peptic ulcer and duodenal ulcer |
| US20110166098A1 (en) * | 2010-01-04 | 2011-07-07 | Wu Tsung-Chung | Mixture of hyaluronic acid for treating and preventing inflammatory bowel disease |
| US8575130B2 (en) * | 2010-01-04 | 2013-11-05 | Holy Stone Healthcare Co., Ltd. | Mixture of hyaluronic acid for treating and preventing inflammatory bowel disease |
| US20110166099A1 (en) * | 2010-01-04 | 2011-07-07 | Wu Tsung-Chung | Mixture of hyaluronic acid for treating and preventing peptic ulcer and duodenal ulcer |
| HUE037474T2 (hu) * | 2011-07-07 | 2018-08-28 | Holy Stone Healthcare Co Ltd | Készítmény gyulladással kapcsolatban rendellenesség kezelésében és megelõzésében történõ alkalmazásra |
-
2011
- 2011-07-12 ES ES11173628.6T patent/ES2665254T3/es active Active
- 2011-07-12 EP EP11173628.6A patent/EP2545925B1/en active Active
-
2012
- 2012-07-02 JP JP2014520210A patent/JP2014523435A/ja active Pending
- 2012-07-02 AU AU2012283037A patent/AU2012283037A1/en not_active Abandoned
- 2012-07-02 US US13/996,952 patent/US20140010847A1/en not_active Abandoned
- 2012-07-02 CN CN201280004393.2A patent/CN103702671A/zh active Pending
- 2012-07-02 BR BR112013020809A patent/BR112013020809A2/pt not_active Application Discontinuation
- 2012-07-02 CA CA2823786A patent/CA2823786C/en active Active
- 2012-07-02 EA EA201300609A patent/EA029940B1/ru unknown
- 2012-07-02 WO PCT/US2012/045259 patent/WO2013009519A2/en active Application Filing
- 2012-07-02 KR KR1020137018070A patent/KR20130099193A/ko not_active Application Discontinuation
-
2016
- 2016-08-26 US US15/248,146 patent/US10709731B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| AU2012283037A1 (en) | 2013-07-11 |
| ES2665254T3 (es) | 2018-04-25 |
| NZ613779A (en) | 2015-07-31 |
| EP2545925B1 (en) | 2018-02-14 |
| JP2014523435A (ja) | 2014-09-11 |
| CA2823786C (en) | 2017-01-17 |
| EP2545925A1 (en) | 2013-01-16 |
| US10709731B2 (en) | 2020-07-14 |
| BR112013020809A2 (pt) | 2018-07-10 |
| US20140010847A1 (en) | 2014-01-09 |
| EA029940B1 (ru) | 2018-06-29 |
| CN103702671A (zh) | 2014-04-02 |
| US20160361347A1 (en) | 2016-12-15 |
| WO2013009519A3 (en) | 2013-03-07 |
| KR20130099193A (ko) | 2013-09-05 |
| WO2013009519A2 (en) | 2013-01-17 |
| CA2823786A1 (en) | 2013-01-17 |
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