EA201201677A1 - Производные гетероарилимидазолона в качестве ингибиторов jak - Google Patents

Производные гетероарилимидазолона в качестве ингибиторов jak

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Publication number
EA201201677A1
EA201201677A1 EA201201677A EA201201677A EA201201677A1 EA 201201677 A1 EA201201677 A1 EA 201201677A1 EA 201201677 A EA201201677 A EA 201201677A EA 201201677 A EA201201677 A EA 201201677A EA 201201677 A1 EA201201677 A1 EA 201201677A1
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EA
Eurasian Patent Office
Prior art keywords
derivatives
heteroarilimidazolone
jak inhibitors
jak
heteroarylimidazolone
Prior art date
Application number
EA201201677A
Other languages
English (en)
Inventor
Пол Роберт Иствуд
Хакоб Гонсалес Родригес
Элена Гомес Кастильо
Хорди Бач Танья
Original Assignee
Альмираль, С.А.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43028230&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201201677(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Альмираль, С.А. filed Critical Альмираль, С.А.
Publication of EA201201677A1 publication Critical patent/EA201201677A1/ru

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    • C07—ORGANIC CHEMISTRY
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    • C07D473/00—Heterocyclic compounds containing purine ring systems
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
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    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Abstract

В заявке описаны новые производные гетероарилимидазолона, обладающие химической структурой, описывающейся формулой (I)а также способ их получения, содержащие их фармацевтические композиции и их применение для лечения в качестве ингибиторов киназ Janus (JAK).
EA201201677A 2010-06-15 2011-06-14 Производные гетероарилимидазолона в качестве ингибиторов jak EA201201677A1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10382174A EP2397482A1 (en) 2010-06-15 2010-06-15 Heteroaryl imidazolone derivatives as jak inhibitors
US36505910P 2010-07-16 2010-07-16
PCT/EP2011/002917 WO2011157397A1 (en) 2010-06-15 2011-06-14 Heteroaryl imidazolone derivatives as jak inhibitors

Publications (1)

Publication Number Publication Date
EA201201677A1 true EA201201677A1 (ru) 2013-05-30

Family

ID=43028230

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201201677A EA201201677A1 (ru) 2010-06-15 2011-06-14 Производные гетероарилимидазолона в качестве ингибиторов jak

Country Status (21)

Country Link
US (1) US20130089512A1 (ru)
EP (2) EP2397482A1 (ru)
JP (1) JP2013528630A (ru)
KR (1) KR20130113331A (ru)
CN (1) CN102933583A (ru)
AR (1) AR081932A1 (ru)
AU (1) AU2011267385A1 (ru)
BR (1) BR112012032234A2 (ru)
CA (1) CA2802588A1 (ru)
CL (1) CL2012003564A1 (ru)
CO (1) CO6640257A2 (ru)
CR (1) CR20120634A (ru)
EA (1) EA201201677A1 (ru)
GT (1) GT201200321A (ru)
MX (1) MX2012014017A (ru)
PE (1) PE20130234A1 (ru)
SG (1) SG186163A1 (ru)
TW (1) TW201201811A (ru)
UY (1) UY33454A (ru)
WO (1) WO2011157397A1 (ru)
ZA (1) ZA201207636B (ru)

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KR102409595B1 (ko) 2020-06-29 2022-06-17 한국과학기술연구원 단백질 카이네이즈 csf-1r 억제제로서의 신규 퓨리논 유도체
JP7023026B1 (ja) 2021-05-18 2022-02-21 株式会社アイビー化粧品 Ｊａｋ阻害剤
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AR081932A1 (es) 2012-10-31
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CN102933583A (zh) 2013-02-13
UY33454A (es) 2012-01-31
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BR112012032234A2 (pt) 2016-11-29
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