EA201100947A1 - Растворимые полипептиды, предназначенные для применения при лечении аутоиммунных и воспалительных нарушений - Google Patents

Растворимые полипептиды, предназначенные для применения при лечении аутоиммунных и воспалительных нарушений

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Publication number
EA201100947A1
EA201100947A1 EA201100947A EA201100947A EA201100947A1 EA 201100947 A1 EA201100947 A1 EA 201100947A1 EA 201100947 A EA201100947 A EA 201100947A EA 201100947 A EA201100947 A EA 201100947A EA 201100947 A1 EA201100947 A1 EA 201100947A1
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Prior art keywords
autoimmune
treatment
inflammatory disorders
application
soluble polypeptides
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EA201100947A
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English (en)
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Марианне Раймон
Мари Сарфати
Карл Вельценбах
Максимилиан Войзечлэгер
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Новартис Аг
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Publication of EA201100947A1 publication Critical patent/EA201100947A1/ru

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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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Abstract

В заявке описаны растворимые связывающие CD47 полипептиды, предназначенные для применения в качестве лекарственного средства, прежде всего для предупреждения или лечения аутоиммунных и воспалительных нарушений, например, аллергической астмы и воспалительного заболевания кишечника. Более конкретно, в заявке описан растворимый связывающий CD47 полипептид, предназначенный для применения в качестве лекарственного средства, который содержит внеклеточный домен SIRPα (CD172a) или его функциональные производные, обладающие способностью связываться с человеческим CD47.
EA201100947A 2008-12-19 2009-12-17 Растворимые полипептиды, предназначенные для применения при лечении аутоиммунных и воспалительных нарушений EA201100947A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP08172369 2008-12-19
US20355808P 2008-12-22 2008-12-22
EP08172751 2008-12-23
PCT/EP2009/067411 WO2010070047A1 (en) 2008-12-19 2009-12-17 Soluble polypeptides for use in treating autoimmune and inflammatory disorders

Publications (1)

Publication Number Publication Date
EA201100947A1 true EA201100947A1 (ru) 2012-02-28

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EA201100947A EA201100947A1 (ru) 2008-12-19 2009-12-17 Растворимые полипептиды, предназначенные для применения при лечении аутоиммунных и воспалительных нарушений

Country Status (11)

Country Link
US (1) US20110237498A1 (ru)
EP (1) EP2379584A1 (ru)
JP (1) JP2012512640A (ru)
KR (1) KR20110112299A (ru)
CN (1) CN102257001A (ru)
AU (1) AU2009327058A1 (ru)
BR (1) BRPI0923442A2 (ru)
CA (1) CA2747678A1 (ru)
EA (1) EA201100947A1 (ru)
MX (1) MX2011006621A (ru)
WO (1) WO2010070047A1 (ru)

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JP2012512640A (ja) 2012-06-07
CA2747678A1 (en) 2010-06-24
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