EA201100156A1 - ПОЛУЧЕНИЕ ДИКАРБОНОВЫХ КИСЛОТ ПРИ НИЗКИХ pH - Google Patents

ПОЛУЧЕНИЕ ДИКАРБОНОВЫХ КИСЛОТ ПРИ НИЗКИХ pH

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Publication number
EA201100156A1
EA201100156A1 EA201100156A EA201100156A EA201100156A1 EA 201100156 A1 EA201100156 A1 EA 201100156A1 EA 201100156 A EA201100156 A EA 201100156A EA 201100156 A EA201100156 A EA 201100156A EA 201100156 A1 EA201100156 A1 EA 201100156A1
Authority
EA
Eurasian Patent Office
Prior art keywords
obtaining
low
acid
dicarbonic acids
product
Prior art date
Application number
EA201100156A
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English (en)
Other versions
EA018463B1 (ru
Inventor
Михель Леонардус Аугуст Янсен
Рене Вервал
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ДСМ АйПи АССЕТС Б.В.
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Application filed by ДСМ АйПи АССЕТС Б.В. filed Critical ДСМ АйПи АССЕТС Б.В.
Publication of EA201100156A1 publication Critical patent/EA201100156A1/ru
Publication of EA018463B1 publication Critical patent/EA018463B1/ru

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C12P7/46—Dicarboxylic acids having four or less carbon atoms, e.g. fumaric acid, maleic acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44—Polycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/01—Oxidoreductases acting on the CH-CH group of donors (1.3) with NAD+ or NADP+ as acceptor (1.3.1)
    • C12Y103/01006—Fumarate reductase (NADH) (1.3.1.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y103/00—Oxidoreductases acting on the CH-CH group of donors (1.3)
    • C12Y103/05—Oxidoreductases acting on the CH-CH group of donors (1.3) with a quinone or related compound as acceptor (1.3.5)
    • C12Y103/05004—Fumarate reductase (menaquinone) (1.3.5.4)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01032—Phosphoenolpyruvate carboxykinase (GTP) (4.1.1.32)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01038—Phosphoenolpyruvate carboxykinase (diphosphate) (4.1.1.38)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y401/00—Carbon-carbon lyases (4.1)
    • C12Y401/01—Carboxy-lyases (4.1.1)
    • C12Y401/01049—Phosphoenolpyruvate carboxykinase (ATP) (4.1.1.49)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y402/00—Carbon-oxygen lyases (4.2)
    • C12Y402/01—Hydro-lyases (4.2.1)
    • C12Y402/01002—Fumarate hydratase (4.2.1.2)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Настоящее изобретение относится к способу получения дикарбоновых кислот. Способ включает в себя ферментацию дрожжей в присутствии углеводсодержащих субстратов и малых количеств кислорода при значении рН, при которых по меньшей мере 50% дикарбоновой кислоты находится в кислотной форме. Способ настоящего изобретения обеспечивает высокие выходы дикарбоновой кислоты-продукта и является более экономичным по сравнению с существующими способами, в которых образуется соль, которую далее необходимо превращать в кислоту. Способ обеспечивает также более простую и более удобную обработку продукта.
EA201100156A 2008-07-08 2009-05-20 ПОЛУЧЕНИЕ ДИКАРБОНОВЫХ КИСЛОТ ПРИ НИЗКИХ pH EA018463B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08159891 2008-07-08
PCT/EP2009/056181 WO2010003728A1 (en) 2008-07-08 2009-05-20 Dicarboxylic acid production by fermentation at low ph

Publications (2)

Publication Number Publication Date
EA201100156A1 true EA201100156A1 (ru) 2011-08-30
EA018463B1 EA018463B1 (ru) 2013-08-30

Family

ID=40329358

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201100156A EA018463B1 (ru) 2008-07-08 2009-05-20 ПОЛУЧЕНИЕ ДИКАРБОНОВЫХ КИСЛОТ ПРИ НИЗКИХ pH

Country Status (10)

Country Link
US (2) US9012187B2 (ru)
EP (2) EP3176265A1 (ru)
CN (3) CN102089436A (ru)
BR (1) BRPI0915534B1 (ru)
CA (1) CA2730595C (ru)
EA (1) EA018463B1 (ru)
ES (1) ES2623932T3 (ru)
PL (1) PL2297297T3 (ru)
UA (1) UA103033C2 (ru)
WO (1) WO2010003728A1 (ru)

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JP5857954B2 (ja) 2010-03-09 2016-02-10 三菱化学株式会社 コハク酸の製造方法
US8624059B2 (en) 2010-03-26 2014-01-07 Bioamber S.A.S. Processes for producing monoammonium succinate from fermentation broths containing diammonium succinate, monoammonium succinate and/or succinic acid, and conversion of monoammonium succinate to succinic acid
US8399687B2 (en) 2010-04-01 2013-03-19 Bioamber International S.A.R.L. Processes for the production of hydrogenated products
US8410291B2 (en) 2010-04-01 2013-04-02 BioAmber International S.á.r.l. Processes for the production of hydrogenated products
US20110269993A1 (en) 2010-04-30 2011-11-03 Bioamber S.A.S. Processes for producing adipic acid from fermentation broths containing diammonium adipate
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WO2012038390A1 (en) * 2010-09-24 2012-03-29 Dsm Ip Assets B.V. Dicarboxylic acid production process
EP2668281A4 (en) 2011-01-25 2015-08-26 Cargill Inc COMPOSITIONS AND METHODS OF SUCCINATE MANUFACTURE
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US8728798B2 (en) 2011-05-03 2014-05-20 Verdezyne, Inc. Biological methods for preparing adipic acid
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WO2012170060A1 (en) 2011-06-10 2012-12-13 Bioamber S.A.S. Processes for producing hexanediol (hdo), hexamethylenediamine (hmd), and derivatives thereof
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Also Published As

Publication number Publication date
CN107267561A (zh) 2017-10-20
EP2297297A1 (en) 2011-03-23
BRPI0915534A2 (pt) 2020-08-18
US20150232891A1 (en) 2015-08-20
EA018463B1 (ru) 2013-08-30
EP3176265A1 (en) 2017-06-07
CA2730595C (en) 2014-12-16
US20110229945A1 (en) 2011-09-22
CN107267562A (zh) 2017-10-20
PL2297297T3 (pl) 2017-08-31
US9340805B2 (en) 2016-05-17
ES2623932T3 (es) 2017-07-12
WO2010003728A4 (en) 2010-04-08
EP2297297B1 (en) 2017-02-08
CA2730595A1 (en) 2010-01-14
UA103033C2 (ru) 2013-09-10
WO2010003728A1 (en) 2010-01-14
CN102089436A (zh) 2011-06-08
US9012187B2 (en) 2015-04-21
BRPI0915534B1 (pt) 2021-04-20

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