EA201070818A1 - ПРОИЗВОДНЫЕ N-ГЕТЕРОЦИКЛИЧЕСКИХ-6-ГЕТЕРОЦИКЛИЧЕСКИХ-ИМИДАЗО[1,2a]ПИРИДИН-2-КАРБОКСАМИДОВ, ИХ ПОЛУЧЕНИЕ И ИХ ПРИМЕНЕНИЕ В ТЕРАПИИ - Google Patents

ПРОИЗВОДНЫЕ N-ГЕТЕРОЦИКЛИЧЕСКИХ-6-ГЕТЕРОЦИКЛИЧЕСКИХ-ИМИДАЗО[1,2a]ПИРИДИН-2-КАРБОКСАМИДОВ, ИХ ПОЛУЧЕНИЕ И ИХ ПРИМЕНЕНИЕ В ТЕРАПИИ

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Publication number
EA201070818A1
EA201070818A1 EA201070818A EA201070818A EA201070818A1 EA 201070818 A1 EA201070818 A1 EA 201070818A1 EA 201070818 A EA201070818 A EA 201070818A EA 201070818 A EA201070818 A EA 201070818A EA 201070818 A1 EA201070818 A1 EA 201070818A1
Authority
EA
Eurasian Patent Office
Prior art keywords
heterocyclic
therapy
group
carboxamides
imidazo
Prior art date
Application number
EA201070818A
Other languages
English (en)
Inventor
Жан-Франсуа Пэронель
Original Assignee
Санофи-Авентис
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Санофи-Авентис filed Critical Санофи-Авентис
Publication of EA201070818A1 publication Critical patent/EA201070818A1/ru

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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
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    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
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    • A—HUMAN NECESSITIES
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    • A61P25/00—Drugs for disorders of the nervous system
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
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    • A61P9/00—Drugs for disorders of the cardiovascular system
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/22—Tin compounds
    • C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
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  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
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  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Immunology (AREA)
  • Psychiatry (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

Соединения формулы (I)где Х означает гетероциклическую группу, в случае необходимости замещенную; Rозначает атом водорода, атом галогена, (C-С)алкосигруппу, (C-С)алкилгруппу, аминогруппу или NRaRb; Rозначает гетероциклическую или гетероароматическую группу, в случае необходимости замещенную; Rозначает атом водорода; (C-C)алкилгруппу, (C-C)алкосигруппу или атом галогена; Rозначает атом водорода, (C-С)алкилгруппу, (C-С)алкоксигруппу или атом фтора, в виде основания или соли присоединения с кислотой. Применение в терапии.
EA201070818A 2008-01-02 2008-12-31 ПРОИЗВОДНЫЕ N-ГЕТЕРОЦИКЛИЧЕСКИХ-6-ГЕТЕРОЦИКЛИЧЕСКИХ-ИМИДАЗО[1,2a]ПИРИДИН-2-КАРБОКСАМИДОВ, ИХ ПОЛУЧЕНИЕ И ИХ ПРИМЕНЕНИЕ В ТЕРАПИИ EA201070818A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0800006A FR2925904B1 (fr) 2008-01-02 2008-01-02 DERIVES DE N-HETEROCYCLIQUE-6-HETEROCYCLIQUE-IMIDAZO°1,2-a! PYRIDINE-2-CARBOXAMIDES, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
PCT/FR2008/001838 WO2009106751A2 (fr) 2008-01-02 2008-12-31 Dérivés de n-heterocyclique-6-heterocyclique-imidazo[1,2- a]pyridiνe-2-carb0xamides, leur préparation et leur application en thérapeutique

Publications (1)

Publication Number Publication Date
EA201070818A1 true EA201070818A1 (ru) 2011-02-28

Family

ID=39768560

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201070818A EA201070818A1 (ru) 2008-01-02 2008-12-31 ПРОИЗВОДНЫЕ N-ГЕТЕРОЦИКЛИЧЕСКИХ-6-ГЕТЕРОЦИКЛИЧЕСКИХ-ИМИДАЗО[1,2a]ПИРИДИН-2-КАРБОКСАМИДОВ, ИХ ПОЛУЧЕНИЕ И ИХ ПРИМЕНЕНИЕ В ТЕРАПИИ

Country Status (23)

Country Link
US (1) US20100317686A1 (ru)
EP (1) EP2225243B1 (ru)
JP (1) JP2011508762A (ru)
KR (1) KR20100103660A (ru)
CN (1) CN101959885A (ru)
AR (1) AR070075A1 (ru)
AT (1) ATE533767T1 (ru)
AU (1) AU2008351929A1 (ru)
BR (1) BRPI0821823A2 (ru)
CA (1) CA2710794A1 (ru)
CL (1) CL2008003929A1 (ru)
CO (1) CO6331311A2 (ru)
EA (1) EA201070818A1 (ru)
FR (1) FR2925904B1 (ru)
IL (1) IL206672A0 (ru)
MA (1) MA32058B1 (ru)
MX (1) MX2010007352A (ru)
PA (1) PA8810201A1 (ru)
PE (1) PE20091531A1 (ru)
TW (1) TW200936133A (ru)
UY (1) UY31590A1 (ru)
WO (1) WO2009106751A2 (ru)
ZA (1) ZA201004646B (ru)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2925907B1 (fr) * 2008-01-02 2010-10-15 Sanofi Aventis DERIVES DE 2-HETEROAROYL-IMIDAZO°1,2-a!PYRIDINE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
WO2012147890A1 (ja) * 2011-04-27 2012-11-01 持田製薬株式会社 新規アゾール誘導体

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004103991A1 (fr) * 2003-05-20 2004-12-02 'chemical Diversity Research Institute', Ltd. Piperidines 2-substituees, bibliotheque focalisee et composition pharmaceutique
US7544803B2 (en) * 2004-01-23 2009-06-09 Amgen Inc. Vanilloid receptor ligands and their use in treatments
JPWO2006088246A1 (ja) * 2005-02-18 2008-07-10 武田薬品工業株式会社 Ｇｐｒ３４受容体機能調節剤
BRPI0608581A2 (pt) * 2005-03-14 2010-01-19 Transtech Pharma Inc derivados de benzazol, composiÇÕes e mÉtodos de uso como inibidores de b-secretase
TW200800997A (en) * 2006-03-22 2008-01-01 Astrazeneca Ab Chemical compounds

Also Published As

Publication number Publication date
US20100317686A1 (en) 2010-12-16
CO6331311A2 (es) 2011-10-20
MX2010007352A (es) 2010-08-18
WO2009106751A3 (fr) 2010-02-25
ZA201004646B (en) 2011-09-28
IL206672A0 (en) 2010-12-30
KR20100103660A (ko) 2010-09-27
EP2225243A2 (fr) 2010-09-08
ATE533767T1 (de) 2011-12-15
EP2225243B1 (fr) 2011-11-16
JP2011508762A (ja) 2011-03-17
UY31590A1 (es) 2009-08-03
MA32058B1 (fr) 2011-02-01
FR2925904A1 (fr) 2009-07-03
AU2008351929A1 (en) 2009-09-03
BRPI0821823A2 (pt) 2015-06-16
CA2710794A1 (fr) 2009-09-03
FR2925904B1 (fr) 2010-01-01
PE20091531A1 (es) 2009-10-29
AR070075A1 (es) 2010-03-10
CL2008003929A1 (es) 2010-01-22
WO2009106751A2 (fr) 2009-09-03
CN101959885A (zh) 2011-01-26
TW200936133A (en) 2009-09-01
PA8810201A1 (es) 2009-08-26

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