EA200701779A1 - Производные (1,5-дифенил-1н-пиразол-3-ил)оксадиазола, их получение и их применение в терапии - Google Patents

Производные (1,5-дифенил-1н-пиразол-3-ил)оксадиазола, их получение и их применение в терапии

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Publication number
EA200701779A1
EA200701779A1 EA200701779A EA200701779A EA200701779A1 EA 200701779 A1 EA200701779 A1 EA 200701779A1 EA 200701779 A EA200701779 A EA 200701779A EA 200701779 A EA200701779 A EA 200701779A EA 200701779 A1 EA200701779 A1 EA 200701779A1
Authority
EA
Eurasian Patent Office
Prior art keywords
pyrazol
oxadiazole
diphenyl
therapy
derivatives
Prior art date
Application number
EA200701779A
Other languages
English (en)
Inventor
Франсис Барт
Кристиан Конжи
Патрик Гель
Мюриэлль Ринальди-Кармона
Дидье Ван Брек
Original Assignee
Санофи-Авентис
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35079215&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200701779(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Санофи-Авентис filed Critical Санофи-Авентис
Publication of EA200701779A1 publication Critical patent/EA200701779A1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Abstract

Объектом настоящего изобретения являются соединения, отвечающие формуле (I), в которой Rпредставляет собой гетероциклический радикал, выбранный из радикалов соединений формулы (II); Rпредставляет собой (C-C)алкил или цианогруппу; Rпредставляет собой незамещенный или замещенный фенил; Rпредставляет собой незамещенный или замещенный фенил; а также их гидраты или их сольваты.
EA200701779A 2005-02-21 2006-02-17 Производные (1,5-дифенил-1н-пиразол-3-ил)оксадиазола, их получение и их применение в терапии EA200701779A1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0501860A FR2882365B1 (fr) 2005-02-21 2005-02-21 Derives de 2-(1,5-diphenyl-1h-pyrazol-3-yl)-1,3,4-oxadiazole leur preparation et leur application en therapeutique
PCT/FR2006/000368 WO2006087480A1 (fr) 2005-02-21 2006-02-17 DERIVES DE (l,5-DIPHENYL-lH-PYRAZOL-3-YL)OXADIAZOLE, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE

Publications (1)

Publication Number Publication Date
EA200701779A1 true EA200701779A1 (ru) 2008-02-28

Family

ID=35079215

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200701779A EA200701779A1 (ru) 2005-02-21 2006-02-17 Производные (1,5-дифенил-1н-пиразол-3-ил)оксадиазола, их получение и их применение в терапии

Country Status (25)

Country Link
US (1) US7632852B2 (ru)
EP (1) EP1853595A1 (ru)
JP (1) JP4812778B2 (ru)
KR (1) KR20070107053A (ru)
CN (1) CN101119990A (ru)
AR (1) AR055560A1 (ru)
AU (1) AU2006215443A1 (ru)
BR (1) BRPI0606845A2 (ru)
CA (1) CA2597359A1 (ru)
DO (1) DOP2006000045A (ru)
EA (1) EA200701779A1 (ru)
FR (1) FR2882365B1 (ru)
GT (1) GT200600082A (ru)
IL (1) IL185163A0 (ru)
MA (1) MA29261B1 (ru)
MX (1) MX2007009994A (ru)
NO (1) NO20074763L (ru)
NZ (1) NZ560790A (ru)
PA (1) PA8663901A1 (ru)
PE (1) PE20061038A1 (ru)
SV (1) SV2007002422A (ru)
TW (1) TW200640916A (ru)
UY (1) UY29388A1 (ru)
WO (1) WO2006087480A1 (ru)
ZA (1) ZA200706953B (ru)

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EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
WO2009078498A1 (en) * 2007-12-17 2009-06-25 Green Cross Corporation Biarylpyrazole 4-carboxamides as cannabinoid cb1 receptor ligands
US8470841B2 (en) 2008-07-09 2013-06-25 Sanofi Heterocyclic compounds, processes for their preparation, medicaments comprising these compounds, and the use thereof
KR101318689B1 (ko) 2008-09-25 2013-10-16 주식회사 녹십자 칸나비노이드 ｃｂ1 수용체 길항제로서 황 함유 피라졸-헤테로사이클 유도체
WO2010068601A1 (en) 2008-12-08 2010-06-17 Sanofi-Aventis A crystalline heteroaromatic fluoroglycoside hydrate, processes for making, methods of use and pharmaceutical compositions thereof
ES2443016T3 (es) 2009-08-26 2014-02-17 Sanofi Nuevos hidratos cristalinos de fluoroglicósidos heteroaromáticos, productos farmacéuticos que comprenden estos compuestos, y su empleo
US8933024B2 (en) 2010-06-18 2015-01-13 Sanofi Azolopyridin-3-one derivatives as inhibitors of lipases and phospholipases
WO2012120054A1 (de) 2011-03-08 2012-09-13 Sanofi Di- und trisubstituierte oxathiazinderivate, verfahren zu deren herstellung, ihre verwendung als medikament sowie sie enthaltendes arzneimittel und deren verwendung
US8710050B2 (en) 2011-03-08 2014-04-29 Sanofi Di and tri- substituted oxathiazine derivatives, method for the production, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
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EP2766349B1 (de) 2011-03-08 2016-06-01 Sanofi Mit carbozyklen oder heterozyklen substituierte oxathiazinderivate, verfahren zu deren herstellung, diese verbindungen enthaltende arzneimittel und deren verwendung
US8828995B2 (en) 2011-03-08 2014-09-09 Sanofi Branched oxathiazine derivatives, method for the production thereof, use thereof as medicine and drug containing said derivatives and use thereof
CN109651350B (zh) * 2019-01-11 2022-05-24 贵州大学 一类杂环取代的1,3,4-噁(噻)二唑类化合物及其制备方法和用途
CN109942567B (zh) * 2019-04-30 2023-04-07 贵州大学 一种1,3,4-噁(噻)二唑基的咪唑类化合物及其制备方法和用途

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SV2007002422A (es) 2007-01-17
BRPI0606845A2 (pt) 2009-07-21
PA8663901A1 (es) 2006-12-07
JP2008530188A (ja) 2008-08-07
ZA200706953B (en) 2009-03-25
IL185163A0 (en) 2007-12-03
US20080039510A1 (en) 2008-02-14
NO20074763L (no) 2007-11-16
PE20061038A1 (es) 2006-11-24
KR20070107053A (ko) 2007-11-06
DOP2006000045A (es) 2006-11-15
FR2882365B1 (fr) 2007-09-07
AU2006215443A1 (en) 2006-08-24
US7632852B2 (en) 2009-12-15
WO2006087480A1 (fr) 2006-08-24
UY29388A1 (es) 2006-10-02
NZ560790A (en) 2009-08-28
AR055560A1 (es) 2007-08-22
GT200600082A (es) 2006-10-19
EP1853595A1 (fr) 2007-11-14
FR2882365A1 (fr) 2006-08-25
CA2597359A1 (fr) 2006-08-24
MX2007009994A (es) 2007-10-10
CN101119990A (zh) 2008-02-06
MA29261B1 (fr) 2008-02-01
TW200640916A (en) 2006-12-01
JP4812778B2 (ja) 2011-11-09

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