EA200601510A1 - Производные фенилэтаноламина в качестве бета-2-агонистов - Google Patents

Производные фенилэтаноламина в качестве бета-2-агонистов

Info

Publication number
EA200601510A1
EA200601510A1 EA200601510A EA200601510A EA200601510A1 EA 200601510 A1 EA200601510 A1 EA 200601510A1 EA 200601510 A EA200601510 A EA 200601510A EA 200601510 A EA200601510 A EA 200601510A EA 200601510 A1 EA200601510 A1 EA 200601510A1
Authority
EA
Eurasian Patent Office
Prior art keywords
derivatives
phenylethanolamine
agonists
beta
compounds
Prior art date
Application number
EA200601510A
Other languages
English (en)
Inventor
Алан Дэниел Браун
Марк Эдуард Баннидж
Пол Алан Глоссоп
Ким Джеймс
Шарлотта Элис Луиза Лейн
Рассел Эндрю Льютуэйт
Грейам Ланн
Дейвид Энтони Прайс
Original Assignee
Пфайзер Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from EP04290725A external-priority patent/EP1577291A1/en
Priority claimed from GB0425064A external-priority patent/GB0425064D0/en
Application filed by Пфайзер Инк. filed Critical Пфайзер Инк.
Publication of EA200601510A1 publication Critical patent/EA200601510A1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Изобретение относится к соединениям формулы (1) и к способам получения таких производных, промежуточным соединениям, используемым в получении таких производных, композициям, содержащим такие производные, и к применению таких производных. Соединения по настоящему изобретению полезны при многих заболеваниях, расстройствах и состояниях, в частности воспалительных, аллергических и респираторных заболеваниях, расстройствах и состояниях.
EA200601510A 2004-03-17 2005-03-10 Производные фенилэтаноламина в качестве бета-2-агонистов EA200601510A1 (ru)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP04290725A EP1577291A1 (en) 2004-03-17 2004-03-17 Phenylethanolamine derivatives as beta-2 agonists
US59179004P 2004-07-27 2004-07-27
GB0425064A GB0425064D0 (en) 2004-11-12 2004-11-12 Compounds useful for the treatment of diseases
PCT/IB2005/000640 WO2005090287A2 (en) 2004-03-17 2005-03-10 Phenylethanolamine derivatives as beta-2 agonists

Publications (1)

Publication Number Publication Date
EA200601510A1 true EA200601510A1 (ru) 2007-04-27

Family

ID=56290672

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200601510A EA200601510A1 (ru) 2004-03-17 2005-03-10 Производные фенилэтаноламина в качестве бета-2-агонистов

Country Status (7)

Country Link
EP (1) EP1727789A2 (ru)
JP (1) JP4054366B2 (ru)
AU (1) AU2005223488A1 (ru)
BR (1) BRPI0508927A (ru)
CA (1) CA2559203A1 (ru)
EA (1) EA200601510A1 (ru)
WO (1) WO2005090287A2 (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0425054D0 (en) * 2004-03-23 2004-12-15 Pfizer Ltd Formamide derivatives for the treatment of diseases
UA87854C2 (en) 2004-06-07 2009-08-25 Мерк Энд Ко., Инк. N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
GB0601951D0 (en) 2006-01-31 2006-03-15 Novartis Ag Organic compounds
ES2320961B1 (es) * 2007-11-28 2010-03-17 Laboratorios Almirall, S.A. Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2.
PL2231642T3 (pl) 2008-01-11 2014-04-30 Novartis Ag Pirymidyny jako inhibitory kinazy
JP5801997B2 (ja) 2009-07-07 2015-10-28 ファイザー・リミテッドＰｆｉｚｅｒ Ｌｉｍｉｔｅｄ 薬品の組合せを吸入するための投薬ユニット、投薬ユニットのパック、および吸入器
US8637516B2 (en) 2010-09-09 2014-01-28 Irm Llc Compounds and compositions as TRK inhibitors
WO2012034095A1 (en) 2010-09-09 2012-03-15 Irm Llc Compounds and compositions as trk inhibitors
CA2828219A1 (en) 2011-02-25 2012-08-30 Irm Llc Pyrazolo [1,5-a] pyridines as trk inhibitors
CN116033893A (zh) 2020-06-26 2023-04-28 迈兰制药英国有限公司 包含5-[3-(3-羟基苯氧基)氮杂环丁烷-1-基]-5-甲基-2,2-二苯基己酰胺的制剂

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1529972A (en) * 1975-07-29 1978-10-25 Allen & Hanburys Ltd Basic alcohols
DE2965655D1 (en) * 1978-06-28 1983-07-21 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
LU85856A1 (fr) * 1984-04-17 1986-06-11 Glaxo Group Ltd Composes de phenethanolamine
GB8528633D0 (en) * 1985-11-21 1985-12-24 Beecham Group Plc Compounds
OA11558A (en) * 1999-12-08 2004-06-03 Advanced Medicine Inc Beta 2-adrenergic receptor agonists.
US6653323B2 (en) * 2001-11-13 2003-11-25 Theravance, Inc. Aryl aniline β2 adrenergic receptor agonists
EP1497261B1 (en) * 2002-04-25 2007-12-19 Glaxo Group Limited Phenethanolamine derivatives
EP1477167A1 (en) * 2003-05-15 2004-11-17 Pfizer Limited [(2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl] phenyl derivatives as beta2 agonists

Also Published As

Publication number Publication date
CA2559203A1 (en) 2005-09-29
EP1727789A2 (en) 2006-12-06
JP2007529501A (ja) 2007-10-25
WO2005090287A3 (en) 2006-02-16
AU2005223488A1 (en) 2005-09-29
WO2005090287A2 (en) 2005-09-29
JP4054366B2 (ja) 2008-02-27
BRPI0508927A (pt) 2007-08-14

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