EA200100702A1 - Сочетания ингибиторов транспорта желчных кислот в подвздошной кишке и агентов, секвестрирующих желчные кислоты, для сердечно-сосудистых показаний - Google Patents

Сочетания ингибиторов транспорта желчных кислот в подвздошной кишке и агентов, секвестрирующих желчные кислоты, для сердечно-сосудистых показаний

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Publication number
EA200100702A1
EA200100702A1 EA200100702A EA200100702A EA200100702A1 EA 200100702 A1 EA200100702 A1 EA 200100702A1 EA 200100702 A EA200100702 A EA 200100702A EA 200100702 A EA200100702 A EA 200100702A EA 200100702 A1 EA200100702 A1 EA 200100702A1
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EA
Eurasian Patent Office
Prior art keywords
acids
combinations
transport
securative
pidatus
Prior art date
Application number
EA200100702A
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English (en)
Other versions
EA004877B1 (ru
Inventor
Брэдли Т. КЕЛЛЕР
Кевин К. Гленн
Джозеф Р. Шух
Original Assignee
Джи.Ди.Сирл Ллс
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26811681&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200100702(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Джи.Ди.Сирл Ллс filed Critical Джи.Ди.Сирл Ллс
Publication of EA200100702A1 publication Critical patent/EA200100702A1/ru
Publication of EA004877B1 publication Critical patent/EA004877B1/ru

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

Настоящее изобретение предоставляет сочетания сердечно-сосудистых терапевтических соединений, предназначенных для профилактики или лечения сердечно-сосудистого заболевания, включая гиперхолестеринемию, атеросклероз или гиперлипидемию. Раскрытые сочетания включают ингибитор транспорта желчных кислот в подвздошной кишке вместе с соединением, удаляющим желчные кислоты.Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200100702A 1998-12-23 1999-12-17 Сочетания ингибиторов транспорта желчных кислот в подвздошной кишке и агентов, секвестрирующих желчные кислоты, для сердечно-сосудистых показаний EA004877B1 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11395598P 1998-12-23 1998-12-23
US14304399P 1999-07-07 1999-07-07
PCT/US1999/027949 WO2000038728A1 (en) 1998-12-23 1999-12-17 Combinations of ileal bile acid transport inhibitors and bile acid sequestring agents for cardiovascular indications

Publications (2)

Publication Number Publication Date
EA200100702A1 true EA200100702A1 (ru) 2001-12-24
EA004877B1 EA004877B1 (ru) 2004-08-26

Family

ID=26811681

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200100702A EA004877B1 (ru) 1998-12-23 1999-12-17 Сочетания ингибиторов транспорта желчных кислот в подвздошной кишке и агентов, секвестрирующих желчные кислоты, для сердечно-сосудистых показаний

Country Status (24)

Country Link
US (2) US6562860B1 (ru)
EP (1) EP1140190B1 (ru)
JP (1) JP2002533414A (ru)
KR (1) KR20010102965A (ru)
CN (1) CN1338945A (ru)
AR (1) AR022022A1 (ru)
AT (1) ATE228012T1 (ru)
AU (1) AU776953B2 (ru)
BR (1) BR9916484A (ru)
CA (1) CA2356156A1 (ru)
CZ (1) CZ20012345A3 (ru)
DE (1) DE69904079T2 (ru)
DK (1) DK1140190T3 (ru)
EA (1) EA004877B1 (ru)
ES (1) ES2189529T3 (ru)
HK (1) HK1044292A1 (ru)
HU (1) HUP0104745A3 (ru)
IL (1) IL143943A0 (ru)
MX (1) MXPA01006470A (ru)
NO (1) NO20013159L (ru)
NZ (1) NZ512535A (ru)
PL (1) PL348609A1 (ru)
PT (1) PT1140190E (ru)
WO (1) WO2000038728A1 (ru)

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US6562860B1 (en) 2003-05-13
PT1140190E (pt) 2003-02-28
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EA004877B1 (ru) 2004-08-26
AR022022A1 (es) 2002-09-04
JP2002533414A (ja) 2002-10-08
MXPA01006470A (es) 2003-06-06
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DK1140190T3 (da) 2002-12-23
US20040029845A1 (en) 2004-02-12
NO20013159L (no) 2001-08-22
ATE228012T1 (de) 2002-12-15
DE69904079T2 (de) 2003-07-17
AU2348000A (en) 2000-07-31
CZ20012345A3 (cs) 2001-12-12
AU776953B2 (en) 2004-09-30
IL143943A0 (en) 2002-04-21
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HUP0104745A2 (hu) 2002-04-29
DE69904079D1 (de) 2003-01-02
KR20010102965A (ko) 2001-11-17
CN1338945A (zh) 2002-03-06
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