EA200001028A1 - Производные 2"-деоксигигромицина - Google Patents

Производные 2"-деоксигигромицина

Info

Publication number
EA200001028A1
EA200001028A1 EA200001028A EA200001028A EA200001028A1 EA 200001028 A1 EA200001028 A1 EA 200001028A1 EA 200001028 A EA200001028 A EA 200001028A EA 200001028 A EA200001028 A EA 200001028A EA 200001028 A1 EA200001028 A1 EA 200001028A1
Authority
EA
Eurasian Patent Office
Prior art keywords
formula
compounds
infectious diseases
relates
protozoal
Prior art date
Application number
EA200001028A
Other languages
English (en)
Other versions
EA004374B1 (ru
Inventor
Роберт Джеральд II Линд
Original Assignee
Пфайзер Продактс Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пфайзер Продактс Инк. filed Critical Пфайзер Продактс Инк.
Publication of EA200001028A1 publication Critical patent/EA200001028A1/ru
Publication of EA004374B1 publication Critical patent/EA004374B1/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26—Acyclic or carbocyclic radicals, substituted by hetero rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

Это изобретение относится к соединениям формулы (1)и их фармацевтически приемлемым солям, пролекарствам и сольватам, где Rи Rтакие, как определено здесь. Соединения формулы (1) являются антибактериальными и антипротозойными агентами, которые можно использовать для лечения различных бактериальных и протозойных инфекционных заболеваний и нарушений, связанных с такими инфекционным заболеваниям. Это изобретение относится также к фармацевтическим композициям, содержащим соединения формулы (1), и способам лечения бактериальных и протозойных инфекционных заболеваний введением соединений формулы (1).Международная заявка была опубликована вместе с отчетом о международном поиске.
EA200001028A 1998-05-04 1999-04-08 Производные 2"-деоксигигромицина EA004374B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8405898P 1998-05-04 1998-05-04
PCT/IB1999/000611 WO1999057127A1 (en) 1998-05-04 1999-04-08 2'-deoxy hygromycin derivatives

Publications (2)

Publication Number Publication Date
EA200001028A1 true EA200001028A1 (ru) 2001-04-23
EA004374B1 EA004374B1 (ru) 2004-04-29

Family

ID=22182624

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200001028A EA004374B1 (ru) 1998-05-04 1999-04-08 Производные 2"-деоксигигромицина

Country Status (38)

Country Link
US (1) US6342497B1 (ru)
EP (1) EP1077984B1 (ru)
JP (1) JP2002513798A (ru)
KR (1) KR100396099B1 (ru)
CN (1) CN1299367A (ru)
AP (1) AP1069A (ru)
AR (1) AR015776A1 (ru)
AT (1) ATE243218T1 (ru)
AU (1) AU762302B2 (ru)
BG (1) BG104995A (ru)
BR (1) BR9910232A (ru)
CA (1) CA2331261C (ru)
DE (1) DE69908936T2 (ru)
DK (1) DK1077984T3 (ru)
DZ (1) DZ2779A1 (ru)
EA (1) EA004374B1 (ru)
ES (1) ES2199559T3 (ru)
GT (1) GT199900058A (ru)
HN (1) HN1999000064A (ru)
HR (1) HRP20000748A2 (ru)
HU (1) HUP0102412A3 (ru)
ID (1) ID26368A (ru)
IL (1) IL139020A0 (ru)
IS (1) IS5680A (ru)
MA (1) MA26626A1 (ru)
NO (1) NO20005551L (ru)
NZ (1) NZ507450A (ru)
OA (1) OA11507A (ru)
PA (1) PA8471901A1 (ru)
PE (1) PE20000440A1 (ru)
PL (1) PL344085A1 (ru)
PT (1) PT1077984E (ru)
SK (1) SK16442000A3 (ru)
TN (1) TNSN99084A1 (ru)
TR (1) TR200003249T2 (ru)
WO (1) WO1999057127A1 (ru)
YU (1) YU64300A (ru)
ZA (1) ZA993063B (ru)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK7302001A3 (en) * 1998-12-02 2001-12-03 Pfizer Prod Inc Hygromycin a derivatives as antibacterial agents
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
PL359179A1 (en) 2000-06-02 2004-08-23 Pfizer Products Inc. Hygromycin a derivatives for the treatment of bacterial and protozoal infections
CN102168034B (zh) * 2010-11-29 2012-12-05 中国科学院南海海洋研究所 一种海洋链霉菌以及利用该菌制备替达霉素a和b的方法
US20210275559A1 (en) * 2018-08-20 2021-09-09 Kim Lewis Hygromycin a compounds and methods of treating spirochete diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2832356B2 (ja) * 1988-03-31 1998-12-09 武田薬品工業株式会社 ハイグロマイシン類の合成中間体および製造法

Also Published As

Publication number Publication date
ID26368A (id) 2000-12-14
BR9910232A (pt) 2001-01-09
AP1069A (en) 2002-05-14
HUP0102412A3 (en) 2003-07-28
DZ2779A1 (fr) 2005-04-23
AP9901525A0 (en) 1999-06-30
ATE243218T1 (de) 2003-07-15
NO20005551D0 (no) 2000-11-03
PT1077984E (pt) 2003-09-30
AU2850899A (en) 1999-11-23
ZA993063B (en) 2000-11-03
DE69908936D1 (en) 2003-07-24
HRP20000748A2 (en) 2001-06-30
JP2002513798A (ja) 2002-05-14
EA004374B1 (ru) 2004-04-29
YU64300A (sh) 2003-07-07
MA26626A1 (fr) 2004-12-20
AR015776A1 (es) 2001-05-16
IS5680A (is) 2000-10-24
WO1999057127A1 (en) 1999-11-11
EP1077984A1 (en) 2001-02-28
DK1077984T3 (da) 2003-09-15
IL139020A0 (en) 2001-11-25
NO20005551L (no) 2001-01-02
AU762302B2 (en) 2003-06-19
TR200003249T2 (tr) 2001-03-21
HUP0102412A2 (hu) 2001-11-28
PA8471901A1 (es) 2000-09-29
ES2199559T3 (es) 2004-02-16
HN1999000064A (es) 2000-01-12
TNSN99084A1 (fr) 2005-11-10
KR20010043267A (ko) 2001-05-25
PL344085A1 (en) 2001-09-24
CN1299367A (zh) 2001-06-13
SK16442000A3 (sk) 2001-07-10
NZ507450A (en) 2003-08-29
PE20000440A1 (es) 2000-05-26
EP1077984B1 (en) 2003-06-18
KR100396099B1 (ko) 2003-08-27
OA11507A (en) 2004-05-13
DE69908936T2 (de) 2004-05-19
CA2331261C (en) 2004-07-27
GT199900058A (es) 2000-10-07
US6342497B1 (en) 2002-01-29
BG104995A (bg) 2001-07-31
CA2331261A1 (en) 1999-11-11

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Legal Events

Date Code Title Description
MM4A Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s)

Designated state(s): AM AZ BY KZ KG MD TJ TM RU