DZ748A1 - Les diesters asymétriques de 1,4-dihydro-2,6-diméthyle-pyridine 3,5-d'acide dicarboxylique. - Google Patents

Les diesters asymétriques de 1,4-dihydro-2,6-diméthyle-pyridine 3,5-d'acide dicarboxylique.

Info

Publication number
DZ748A1
DZ748A1 DZ850035A DZ850035A DZ748A1 DZ 748 A1 DZ748 A1 DZ 748A1 DZ 850035 A DZ850035 A DZ 850035A DZ 850035 A DZ850035 A DZ 850035A DZ 748 A1 DZ748 A1 DZ 748A1
Authority
DZ
Algeria
Prior art keywords
dihydro
pyridine
dimethyl
dicarboxylic acid
asymmetric diesters
Prior art date
Application number
DZ850035A
Other languages
English (en)
French (fr)
Inventor
Dente Nahdi
Amedeo Leonardi
Gabriele Graziani
Giorgio Bianchi
Original Assignee
Recordati Chem Pharm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10556581&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DZ748(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Recordati Chem Pharm filed Critical Recordati Chem Pharm
Application granted granted Critical
Publication of DZ748A1 publication Critical patent/DZ748A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
DZ850035A 1984-02-14 1985-02-13 Les diesters asymétriques de 1,4-dihydro-2,6-diméthyle-pyridine 3,5-d'acide dicarboxylique. DZ748A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848403866A GB8403866D0 (en) 1984-02-14 1984-02-14 Diphenylalkylaminoalkyl esters

Publications (1)

Publication Number Publication Date
DZ748A1 true DZ748A1 (fr) 2004-09-13

Family

ID=10556581

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ850035A DZ748A1 (fr) 1984-02-14 1985-02-13 Les diesters asymétriques de 1,4-dihydro-2,6-diméthyle-pyridine 3,5-d'acide dicarboxylique.

Country Status (29)

Country Link
US (3) US4705797A (de)
EP (1) EP0153016B1 (de)
JP (1) JPS60199874A (de)
KR (1) KR910005231B1 (de)
AR (1) AR240804A1 (de)
AT (1) ATE52772T1 (de)
AU (1) AU570534B2 (de)
BR (1) BR1101167A (de)
CA (1) CA1277666C (de)
DE (2) DE10199007I2 (de)
DK (1) DK160985C (de)
DZ (1) DZ748A1 (de)
EG (1) EG17772A (de)
ES (1) ES8602664A1 (de)
FI (1) FI83954C (de)
GB (1) GB8403866D0 (de)
GR (1) GR850363B (de)
HU (1) HU194171B (de)
IE (1) IE57715B1 (de)
IL (1) IL74238A (de)
LU (1) LU90069I2 (de)
MX (1) MX156874A (de)
NL (1) NL970025I2 (de)
NO (2) NO166123C (de)
NZ (1) NZ210866A (de)
PH (1) PH20725A (de)
PT (1) PT79963B (de)
SG (1) SG48590G (de)
ZA (1) ZA85656B (de)

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ITMI20011727A1 (it) 2001-08-06 2003-02-06 Recordati Ind Chimica E Farma Solvati della lercanidipina cloridrato e nuove forme cristalline della lercanidipina cloridrato ottenute da essi
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MX2007000979A (es) * 2004-07-26 2007-07-11 Cotherix Inc Tratamiento de la hipertension pulmonar por iloprost inhalado con una formulacion microparticulada.
TW200613275A (en) * 2004-08-24 2006-05-01 Recordati Ireland Ltd Lercanidipine salts
US20060134212A1 (en) * 2004-09-02 2006-06-22 Forest Laboratories, Inc. Lercanidipine immediate release compositions
US20060165788A1 (en) * 2004-09-09 2006-07-27 Wattanaporn Abramowitz Lercanidipine pH dependent pulsatile release compositions
US20060165789A1 (en) * 2004-09-09 2006-07-27 Forest Laboratories, Inc. Lercanidipine modified release compositions
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TW200616681A (en) * 2004-10-05 2006-06-01 Recordati Ireland Ltd Lercanidipine capsules
KR100651212B1 (ko) 2004-10-27 2006-12-01 제일약품주식회사 무정형 레르카니디핀의 제조방법
IL165525A0 (en) * 2004-12-02 2006-01-15 Motivan Ltd Intermediates and a process for the manufacturing for antihypertensive dihydropyridine derivative suitable for pharmaceutical compositions
AR053023A1 (es) * 2005-02-25 2007-04-18 Recordati Ireland Ltd Base libre de lercanidipina, metodos para su preparacion y composiciones farmaceuticas que las contienen
AR052918A1 (es) * 2005-02-25 2007-04-11 Recordati Ireland Ltd Clorhidrato de lercanidipina amorfo
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WO2007031865A2 (en) 2005-09-16 2007-03-22 Glenmark Pharmaceuticals Limited Polymorphic form of lercanidipine hydrochloride and process for the preparation thereof
WO2007054969A2 (en) * 2005-09-21 2007-05-18 Torrent Pharmaceuticals Limited Process for the preparation of lercanidipine and amorphous form of lercanidipine hydrochloride
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EP2351569B1 (de) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Kombinationstherapie mit Fasudil zur Behandlung von pulmonaler Hypertonie
EP2111863B1 (de) 2005-10-26 2012-03-28 Asahi Kasei Pharma Corporation Fasudil in Kombination mit Bosentan zur Behandlung von pulmonaler arterieller Hypertonie
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US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
WO2007120135A1 (en) * 2006-04-17 2007-10-25 Forest Laboratories, Inc. Lercanidipine immediate release composition
ATE415389T1 (de) * 2006-05-24 2008-12-15 Cf Pharma Ltd Verfahren zur herstellung von lercanipidin
DK2046745T3 (da) * 2006-08-04 2014-01-20 Recordati Ireland Ltd Fremgangsmåde til fremstilling af amorft lercanidipin-hydrochlorid
US20080175872A1 (en) * 2006-09-28 2008-07-24 Osmotica Corp. Controlled Release Dosage Form Containing Lercanidipine and a Performance-enhancing Acid
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US8883844B2 (en) 2010-09-24 2014-11-11 Nitrogenix Inc. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
EP2444394A1 (de) 2010-10-21 2012-04-25 Alembic Pharmaceuticals Limited Verfahren zur Herstellung amorpher Formen von Lercanidipin HCl
SI2654729T1 (sl) 2010-12-24 2016-08-31 Krka, D.D., Novo Mesto Homogene farmacevtske oralne dozirne oblike, ki obsegajo lerkanidipin in enalapril ali njune farmacevtsko sprejemljive soli skupaj z organsko kislino
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JPS5762257A (en) * 1980-10-03 1982-04-15 Yoshitomi Pharmaceut Ind Ltd 1,4-dihydropyridine-3,5-dicarboxylic acid ester or its salt
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
EP0080220B1 (de) * 1981-11-17 1986-02-19 FISONS plc Dihydropyridine, Verfahren zu ihrer Herstellung, ihre Zusammensetzungen und ihre Verwendung als Arzneimittel
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AU561213B2 (en) * 1983-06-02 1987-04-30 Teijin Limited 1, 4-dihydropyridine derivative
NO854021L (no) * 1984-10-26 1986-04-28 Bayer Ag 1,4-dihydropyridin-hydroksyaminer og fremgangsmaate til fremstilling derav.
GB8503424D0 (en) * 1985-02-11 1985-03-13 Ici Plc Heterocyclic derivatives

Also Published As

Publication number Publication date
NO850521L (no) 1985-08-15
AR240804A1 (es) 1991-02-28
HU194171B (en) 1988-01-28
IL74238A0 (en) 1985-05-31
IE57715B1 (en) 1993-03-10
ATE52772T1 (de) 1990-06-15
FI850535A0 (fi) 1985-02-08
MX156874A (es) 1988-10-08
FI83954B (fi) 1991-06-14
NL970025I2 (nl) 1998-01-05
JPH0517908B2 (de) 1993-03-10
GB8403866D0 (en) 1984-03-21
EP0153016A2 (de) 1985-08-28
NL970025I1 (nl) 1997-09-01
DE10199007I2 (de) 2003-01-09
EP0153016B1 (de) 1990-05-16
PT79963A (en) 1985-03-01
HUT37399A (en) 1985-12-28
SG48590G (en) 1990-08-17
EG17772A (en) 1991-08-30
ES540385A0 (es) 1985-11-16
NO166123B (no) 1991-02-25
IE850280L (en) 1985-08-14
AU570534B2 (en) 1988-03-17
CA1277666C (en) 1990-12-11
PT79963B (en) 1986-11-10
NZ210866A (en) 1988-07-28
JPS60199874A (ja) 1985-10-09
FI83954C (fi) 1991-09-25
PH20725A (en) 1987-03-30
EP0153016A3 (en) 1985-10-02
FI850535L (fi) 1985-08-15
GR850363B (de) 1986-02-06
DK63085A (da) 1985-08-15
ES8602664A1 (es) 1985-11-16
US4968832A (en) 1990-11-06
US4705797A (en) 1987-11-10
US4772621A (en) 1988-09-20
NO2000011I1 (no) 2000-10-17
IL74238A (en) 1988-07-31
LU90069I2 (fr) 1997-07-23
KR910005231B1 (ko) 1991-07-24
NO166123C (no) 1991-06-05
AR240804A2 (es) 1991-02-28
DK160985B (da) 1991-05-13
DK63085D0 (da) 1985-02-12
DK160985C (da) 1991-11-04
ZA85656B (en) 1985-08-28
BR1101167A (pt) 2004-08-17
DE3577703D1 (de) 1990-06-21
KR850005826A (ko) 1985-09-26
AU3868985A (en) 1985-09-12
DE10199007I1 (de) 2001-04-12

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