DZ3236A1 - Procédé pour la purification de proteines actives pharmacologiquement par chromatographie d'échange de cations - Google Patents

Procédé pour la purification de proteines actives pharmacologiquement par chromatographie d'échange de cations

Info

Publication number
DZ3236A1
DZ3236A1 DZ020153A DZ020153A DZ3236A1 DZ 3236 A1 DZ3236 A1 DZ 3236A1 DZ 020153 A DZ020153 A DZ 020153A DZ 020153 A DZ020153 A DZ 020153A DZ 3236 A1 DZ3236 A1 DZ 3236A1
Authority
DZ
Algeria
Prior art keywords
purification
cation exchange
exchange chromatography
pharmacologically active
active proteins
Prior art date
Application number
DZ020153A
Other languages
English (en)
Inventor
Giuseppe Claudio Viscomi
Lucia Scapol
Original Assignee
Alfa Waddermann S P A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alfa Waddermann S P A filed Critical Alfa Waddermann S P A
Application granted granted Critical
Publication of DZ3236A1 publication Critical patent/DZ3236A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/76—Albumins
    • C07K14/765—Serum albumin, e.g. HSA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/811—Interferon
DZ020153A 2001-07-06 2002-06-26 Procédé pour la purification de proteines actives pharmacologiquement par chromatographie d'échange de cations DZ3236A1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2001BO000426A ITBO20010426A1 (it) 2001-07-06 2001-07-06 Processo per la purificazione di proteine farmacologicamente attive mediante cromatografia in scambio cationico

Publications (1)

Publication Number Publication Date
DZ3236A1 true DZ3236A1 (fr) 2005-04-20

Family

ID=11439471

Family Applications (1)

Application Number Title Priority Date Filing Date
DZ020153A DZ3236A1 (fr) 2001-07-06 2002-06-26 Procédé pour la purification de proteines actives pharmacologiquement par chromatographie d'échange de cations

Country Status (27)

Country Link
US (1) US6866782B2 (fr)
EP (1) EP1273592B1 (fr)
JP (1) JP3940037B2 (fr)
KR (1) KR100771252B1 (fr)
CN (1) CN100484954C (fr)
AR (1) AR034663A1 (fr)
AT (1) ATE307824T1 (fr)
BG (1) BG65748B1 (fr)
BR (1) BR0202431A (fr)
CA (1) CA2388716C (fr)
CU (1) CU23149A3 (fr)
DE (1) DE60206847T2 (fr)
DK (1) DK1273592T3 (fr)
DZ (1) DZ3236A1 (fr)
EG (1) EG23150A (fr)
ES (1) ES2250544T3 (fr)
HR (1) HRP20020480B1 (fr)
HU (1) HUP0202124A2 (fr)
IT (1) ITBO20010426A1 (fr)
ME (1) MEP3408A (fr)
MX (1) MXPA02006303A (fr)
PL (1) PL209954B1 (fr)
RS (1) RS51512B (fr)
RU (1) RU2274471C2 (fr)
SI (1) SI1273592T1 (fr)
SK (1) SK287827B6 (fr)
UY (1) UY27354A1 (fr)

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WO2004103519A2 (fr) * 2003-05-16 2004-12-02 Cryobiophysica, Inc. Chromatofocalisation a gradient externe
JP3920913B2 (ja) * 2004-03-30 2007-05-30 寛 柳澤 タンパク質の分離方法
US7449116B2 (en) * 2004-10-01 2008-11-11 Agilent Technologies, Inc. Methods and systems for protein separation
US7943046B2 (en) * 2004-10-01 2011-05-17 Agilent Technologies, Inc Methods and systems for on-column protein delipidation
HU230758B1 (hu) * 2006-04-12 2018-03-28 Crealta Pharmaceuticals LLC 100% Fehérjék tisztítása kationos felületaktív anyaggal
US20100261275A1 (en) * 2007-12-10 2010-10-14 Yves Durocher Production of Recombinant Interferon Proteins
DE102009032179A1 (de) 2009-07-07 2011-01-13 Biogenerix Ag Verfahren zur Reinigung von Interferon beta
CN101768601B (zh) * 2010-02-01 2013-08-07 山东泉港药业有限公司 一种重组人血白蛋白—干扰素α2b的生产方法
JP6292718B2 (ja) * 2011-07-01 2018-03-14 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 凝集ポリペプチドから単量体ポリペプチドを分離するための方法
US8921113B2 (en) 2012-12-21 2014-12-30 Dionex Corporation Buffer kit and method of generating a linear pH gradient
SG11201506775VA (en) 2013-03-08 2015-09-29 Genzyme Corp Continuous purification of therapeutic proteins
CN104236983A (zh) * 2013-06-14 2014-12-24 中国科学院大连化学物理研究所 溶液样品中含长烷基链的离子液体的去除方法
TWI709570B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析法及製法
TWI709569B (zh) 2014-01-17 2020-11-11 美商健臻公司 無菌層析樹脂及其用於製造方法的用途
EP3221450A1 (fr) * 2014-11-18 2017-09-27 Unichem Laboratories Limited Procédé amélioré pour la préparation de l'interféron alpha 2b de qualité conforme à la pharmacopée
CN106496302B (zh) * 2015-09-08 2021-12-10 三生国健药业（上海）股份有限公司 一种用离子交换层析纯化蛋白质的方法
GB201517450D0 (en) * 2015-10-02 2015-11-18 Ipsen Biopharm Ltd Method
US20190024038A1 (en) * 2015-12-09 2019-01-24 Basf Se Method of purifying a protein from fermentation solids under desorbing conditions
GB2568936B (en) 2017-12-01 2019-12-25 Ford Global Tech Llc Liquid cooled injector
WO2020046602A1 (fr) 2018-08-31 2020-03-05 Genzyme Corporation Résine de chromatographie stérile et son utilisation dans des procédés de fabrication
US11022585B2 (en) 2019-06-09 2021-06-01 Dionex Corporation Methods and systems for optimizing buffer conditions with liquid chromatography
CN111138523A (zh) * 2019-12-10 2020-05-12 天津生机集团股份有限公司 一种从重组鸡干扰素α复性液中纯化制备重组鸡干扰素α的方法
CN113968900B (zh) * 2020-07-23 2023-07-25 中元汇吉生物技术股份有限公司 一种纯化C1q蛋白的方法
CN115918902A (zh) * 2022-12-19 2023-04-07 新疆农业科学院农业质量标准与检测技术研究所 一种通过微水波扩散重力法预处理葡萄脱水并获取高酚葡萄提取物的方法

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US4228154A (en) * 1979-02-26 1980-10-14 Armour Pharmaceutical Company Purification of plasma albumin by ion exchange chromatography
US4534906A (en) * 1982-11-01 1985-08-13 Genentech, Inc. Removal of impurities from human leukocyte interferon preparations
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US5037644A (en) * 1986-10-27 1991-08-06 Cetus Corporation Pharmaceutical compositions of recombinant interleukin-2 and formulation processes
US4732683A (en) * 1986-12-02 1988-03-22 Biospectrum, Inc. Purification method for alpha interferon
US4765903A (en) * 1987-10-06 1988-08-23 Interferon Sciences, Inc. Purification of monomeric interferon
US5250662A (en) * 1989-10-05 1993-10-05 Alpha Therapeutic Corporation Albumin purification
US5849874A (en) * 1991-07-12 1998-12-15 Gist-Brocades, N.V. Process for the purification of serum albumin
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US5440018A (en) * 1992-05-20 1995-08-08 The Green Cross Corporation Recombinant human serum albumin, process for producing the same and pharmaceutical preparation containing the same
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GB9902000D0 (en) 1999-01-30 1999-03-17 Delta Biotechnology Ltd Process

Also Published As

Publication number Publication date
US20030010715A1 (en) 2003-01-16
DE60206847T2 (de) 2006-07-06
DK1273592T3 (da) 2006-01-02
MXPA02006303A (es) 2003-02-10
PL209954B1 (pl) 2011-11-30
KR20030005005A (ko) 2003-01-15
CA2388716A1 (fr) 2003-01-06
AR034663A1 (es) 2004-03-03
PL354769A1 (en) 2003-01-13
CU23149A3 (es) 2006-06-29
HU0202124D0 (fr) 2002-09-28
ITBO20010426A0 (it) 2001-07-06
BR0202431A (pt) 2003-09-09
CA2388716C (fr) 2008-01-08
JP3940037B2 (ja) 2007-07-04
CN100484954C (zh) 2009-05-06
EP1273592B1 (fr) 2005-10-26
US6866782B2 (en) 2005-03-15
RU2002117383A (ru) 2004-01-27
BG65748B1 (bg) 2009-09-30
ITBO20010426A1 (it) 2003-01-06
EG23150A (en) 2004-05-31
YU50502A (sh) 2005-09-19
SI1273592T1 (sl) 2006-02-28
EP1273592A3 (fr) 2003-03-19
HRP20020480A2 (en) 2003-02-28
EP1273592A2 (fr) 2003-01-08
UY27354A1 (es) 2003-04-30
HUP0202124A2 (hu) 2003-10-28
ATE307824T1 (de) 2005-11-15
SK8592002A3 (en) 2003-01-09
MEP3408A (en) 2010-10-10
JP2003096092A (ja) 2003-04-03
RU2274471C2 (ru) 2006-04-20
KR100771252B1 (ko) 2007-10-30
RS51512B (sr) 2011-06-30
ES2250544T3 (es) 2006-04-16
BG106768A (en) 2003-05-30
SK287827B6 (sk) 2011-11-04
CN1396176A (zh) 2003-02-12
DE60206847D1 (de) 2005-12-01
HRP20020480B1 (en) 2006-11-30

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