DOP2011000108A - Terapia de combinacion con epoxicetonas peptidicas - Google Patents

Terapia de combinacion con epoxicetonas peptidicas

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Publication number
DOP2011000108A
DOP2011000108A DO2011000108A DO2011000108A DOP2011000108A DO P2011000108 A DOP2011000108 A DO P2011000108A DO 2011000108 A DO2011000108 A DO 2011000108A DO 2011000108 A DO2011000108 A DO 2011000108A DO P2011000108 A DOP2011000108 A DO P2011000108A
Authority
DO
Dominican Republic
Prior art keywords
combination therapy
epoxycetones
peptidic
peptide
administered
Prior art date
Application number
DO2011000108A
Other languages
English (en)
Inventor
Christopher J Kirk
Susan D Demo
Mark K Bennett
Original Assignee
Onyx Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42119657&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DOP2011000108(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Onyx Therapeutics Inc filed Critical Onyx Therapeutics Inc
Publication of DOP2011000108A publication Critical patent/DOP2011000108A/es

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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Abstract

La invención proporciona terapia de combinación, donde uno o más de otros agentes terapéuticos se administran con epoxicetonas peptídicas o una sai farmacéuticamente aceptable de las mismas. Otro aspecto de la invención se refiere al tratamiento del cáncer con una epoxicetona peptídica administrada junto con otro agente terapéutico.
DO2011000108A 2008-10-21 2011-04-20 Terapia de combinacion con epoxicetonas peptidicas DOP2011000108A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19694508P 2008-10-21 2008-10-21

Publications (1)

Publication Number Publication Date
DOP2011000108A true DOP2011000108A (es) 2011-07-15

Family

ID=42119657

Family Applications (1)

Application Number Title Priority Date Filing Date
DO2011000108A DOP2011000108A (es) 2008-10-21 2011-04-20 Terapia de combinacion con epoxicetonas peptidicas

Country Status (27)

Country Link
US (5) US20110236428A1 (es)
EP (3) EP3090737A1 (es)
JP (4) JP5675629B2 (es)
KR (1) KR20110073584A (es)
CN (1) CN102256616A (es)
AP (1) AP2011005690A0 (es)
AU (4) AU2009308516B2 (es)
BR (1) BRPI0919668A2 (es)
CA (1) CA2741312C (es)
CL (1) CL2011000916A1 (es)
CO (1) CO6361942A2 (es)
CR (1) CR20110221A (es)
DO (1) DOP2011000108A (es)
EA (2) EA035100B1 (es)
EC (1) ECSP11011027A (es)
ES (1) ES2617560T3 (es)
HK (1) HK1202436A1 (es)
IL (1) IL212506A0 (es)
MA (1) MA32806B1 (es)
ME (1) ME01133B (es)
MX (2) MX2011004225A (es)
NI (1) NI201100077A (es)
PE (1) PE20120059A1 (es)
TN (1) TN2011000200A1 (es)
UA (1) UA104600C2 (es)
WO (1) WO2010048298A1 (es)
ZA (1) ZA201103493B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103554222A (zh) 2004-04-15 2014-02-05 欧尼斯治疗公司 用于抑制蛋白酶体酶的化合物
US8198270B2 (en) 2004-04-15 2012-06-12 Onyx Therapeutics, Inc. Compounds for proteasome enzyme inhibition
NZ595196A (en) 2005-11-09 2013-03-28 Proteolix Inc Peptide-based compounds for enzyme inhibition
PL2041158T3 (pl) 2006-06-19 2013-08-30 Onyx Therapeutics Inc Peptydowe epoksyketony do hamowania proteasomu
PL2207791T5 (pl) 2007-10-04 2020-07-27 Onyx Therapeutics, Inc. Krystaliczne peptydo- epoksy ketonowe inhibitory proteazy i synteza keto-epoksydów Aminokwasowych
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