DOP2011000108A - Terapia de combinacion con epoxicetonas peptidicas - Google Patents
Terapia de combinacion con epoxicetonas peptidicasInfo
- Publication number
- DOP2011000108A DOP2011000108A DO2011000108A DO2011000108A DOP2011000108A DO P2011000108 A DOP2011000108 A DO P2011000108A DO 2011000108 A DO2011000108 A DO 2011000108A DO 2011000108 A DO2011000108 A DO 2011000108A DO P2011000108 A DOP2011000108 A DO P2011000108A
- Authority
- DO
- Dominican Republic
- Prior art keywords
- combination therapy
- epoxycetones
- peptidic
- peptide
- administered
- Prior art date
Links
- 238000002648 combination therapy Methods 0.000 title abstract 2
- 239000003814 drug Substances 0.000 abstract 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N epoxyketone group Chemical group O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 229940124597 therapeutic agent Drugs 0.000 abstract 2
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
Classifications
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
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Abstract
La invención proporciona terapia de combinación, donde uno o más de otros agentes terapéuticos se administran con epoxicetonas peptídicas o una sai farmacéuticamente aceptable de las mismas. Otro aspecto de la invención se refiere al tratamiento del cáncer con una epoxicetona peptídica administrada junto con otro agente terapéutico.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US19694508P | 2008-10-21 | 2008-10-21 |
Publications (1)
Publication Number | Publication Date |
---|---|
DOP2011000108A true DOP2011000108A (es) | 2011-07-15 |
Family
ID=42119657
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DO2011000108A DOP2011000108A (es) | 2008-10-21 | 2011-04-20 | Terapia de combinacion con epoxicetonas peptidicas |
Country Status (27)
Country | Link |
---|---|
US (5) | US20110236428A1 (es) |
EP (3) | EP3090737A1 (es) |
JP (4) | JP5675629B2 (es) |
KR (1) | KR20110073584A (es) |
CN (1) | CN102256616A (es) |
AP (1) | AP2011005690A0 (es) |
AU (4) | AU2009308516B2 (es) |
BR (1) | BRPI0919668A2 (es) |
CA (1) | CA2741312C (es) |
CL (1) | CL2011000916A1 (es) |
CO (1) | CO6361942A2 (es) |
CR (1) | CR20110221A (es) |
DO (1) | DOP2011000108A (es) |
EA (2) | EA035100B1 (es) |
EC (1) | ECSP11011027A (es) |
ES (1) | ES2617560T3 (es) |
HK (1) | HK1202436A1 (es) |
IL (1) | IL212506A0 (es) |
MA (1) | MA32806B1 (es) |
ME (1) | ME01133B (es) |
MX (2) | MX2011004225A (es) |
NI (1) | NI201100077A (es) |
PE (1) | PE20120059A1 (es) |
TN (1) | TN2011000200A1 (es) |
UA (1) | UA104600C2 (es) |
WO (1) | WO2010048298A1 (es) |
ZA (1) | ZA201103493B (es) |
Families Citing this family (33)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103554222A (zh) | 2004-04-15 | 2014-02-05 | 欧尼斯治疗公司 | 用于抑制蛋白酶体酶的化合物 |
US8198270B2 (en) | 2004-04-15 | 2012-06-12 | Onyx Therapeutics, Inc. | Compounds for proteasome enzyme inhibition |
NZ595196A (en) | 2005-11-09 | 2013-03-28 | Proteolix Inc | Peptide-based compounds for enzyme inhibition |
PL2041158T3 (pl) | 2006-06-19 | 2013-08-30 | Onyx Therapeutics Inc | Peptydowe epoksyketony do hamowania proteasomu |
PL2207791T5 (pl) | 2007-10-04 | 2020-07-27 | Onyx Therapeutics, Inc. | Krystaliczne peptydo- epoksy ketonowe inhibitory proteazy i synteza keto-epoksydów Aminokwasowych |
AP2011005690A0 (en) | 2008-10-21 | 2011-06-30 | Onyx Therapeutics Inc | Combination therapy with peptide epoxyketones. |
TWI504598B (zh) | 2009-03-20 | 2015-10-21 | Onyx Therapeutics Inc | 結晶性三肽環氧酮蛋白酶抑制劑 |
JP5919196B2 (ja) | 2009-11-13 | 2016-05-18 | オニキス セラピューティクス, インク.Onyx Therapeutics, Inc. | 転移抑制のためのペプチドエポキシケトンの使用 |
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