CL2011000916A1 - Uso de una combinacion de un inhibidor de proteasoma epoxicetona peptidica o una sal farmaceutica aceptable del mismo, y uno o mas de otros agentes terapeuticos para tratar el cancer. - Google Patents

Uso de una combinacion de un inhibidor de proteasoma epoxicetona peptidica o una sal farmaceutica aceptable del mismo, y uno o mas de otros agentes terapeuticos para tratar el cancer.

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Publication number
CL2011000916A1
CL2011000916A1 CL2011000916A CL2011000916A CL2011000916A1 CL 2011000916 A1 CL2011000916 A1 CL 2011000916A1 CL 2011000916 A CL2011000916 A CL 2011000916A CL 2011000916 A CL2011000916 A CL 2011000916A CL 2011000916 A1 CL2011000916 A1 CL 2011000916A1
Authority
CL
Chile
Prior art keywords
combination
proteasome inhibitor
therapeutic agents
treat cancer
pharmaceutical salt
Prior art date
Application number
CL2011000916A
Other languages
English (en)
Inventor
Christopher J Kirk
Susan D Demo
Mark K Bennett
Original Assignee
Onyx Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42119657&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CL2011000916(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Onyx Therapeutics Inc filed Critical Onyx Therapeutics Inc
Publication of CL2011000916A1 publication Critical patent/CL2011000916A1/es

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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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Abstract

Método de tratamiento con una combinación farmacéutica que comprende un inhibidor de proteasoma peptídico y otro agente terapéutico para el tratamiento del cáncer.
CL2011000916A 2008-10-21 2011-04-21 Uso de una combinacion de un inhibidor de proteasoma epoxicetona peptidica o una sal farmaceutica aceptable del mismo, y uno o mas de otros agentes terapeuticos para tratar el cancer. CL2011000916A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US19694508P 2008-10-21 2008-10-21

Publications (1)

Publication Number Publication Date
CL2011000916A1 true CL2011000916A1 (es) 2011-09-16

Family

ID=42119657

Family Applications (1)

Application Number Title Priority Date Filing Date
CL2011000916A CL2011000916A1 (es) 2008-10-21 2011-04-21 Uso de una combinacion de un inhibidor de proteasoma epoxicetona peptidica o una sal farmaceutica aceptable del mismo, y uno o mas de otros agentes terapeuticos para tratar el cancer.

Country Status (27)

Country Link
US (5) US20110236428A1 (es)
EP (3) EP2796134B1 (es)
JP (4) JP5675629B2 (es)
KR (1) KR20110073584A (es)
CN (1) CN102256616A (es)
AP (1) AP2011005690A0 (es)
AU (4) AU2009308516B2 (es)
BR (1) BRPI0919668A2 (es)
CA (1) CA2741312C (es)
CL (1) CL2011000916A1 (es)
CO (1) CO6361942A2 (es)
CR (1) CR20110221A (es)
DO (1) DOP2011000108A (es)
EA (2) EA035100B1 (es)
EC (1) ECSP11011027A (es)
ES (1) ES2617560T3 (es)
HK (1) HK1202436A1 (es)
IL (1) IL212506A0 (es)
MA (1) MA32806B1 (es)
ME (1) ME01133B (es)
MX (2) MX2011004225A (es)
NI (1) NI201100077A (es)
PE (1) PE20120059A1 (es)
TN (1) TN2011000200A1 (es)
UA (1) UA104600C2 (es)
WO (1) WO2010048298A1 (es)
ZA (1) ZA201103493B (es)

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CN105237621A (zh) 2005-11-09 2016-01-13 欧尼斯治疗公司 用于酶抑制的化合物
EP2041158B1 (en) 2006-06-19 2013-04-17 Onyx Therapeutics, Inc. Peptide epoxyketones for proteasome inhibition
CL2008002966A1 (es) 2007-10-04 2010-06-25 Onyx Therapeutics Inc Compuesto tetrapeptido ceto-epoxido cristalino; sal citrato cristalina del compuesto; metodos de preparacion; compuesto intermediario cristalino; metodo de preparacion; y uso para tratar cancer, enfermedad autoinmune, afeccion relacionada con trasplante, enfermedad neurodegenerativa, afeccion asociada con fibrosis, entre otros.
EA035100B1 (ru) 2008-10-21 2020-04-28 Оникс Терапьютикс, Инк. Комбинированная терапия с применением пептид эпоксикетонов
TWI504598B (zh) 2009-03-20 2015-10-21 Onyx Therapeutics Inc 結晶性三肽環氧酮蛋白酶抑制劑
WO2011060179A1 (en) * 2009-11-13 2011-05-19 Onyx Therapeutics, Inc Use of peptide epoxyketones for metastasis suppression
US9359398B2 (en) 2010-03-01 2016-06-07 Onyx Therapeutics, Inc. Compounds for immunoproteasome inhibition
BR112012025264A2 (pt) 2010-04-07 2019-09-24 Onyx Therapeutics Inc inibidor de imunoproteassoma de e´poxicetona peptídica cristalina.
EP2662094B1 (en) 2012-05-08 2024-04-17 Onyx Therapeutics, Inc. Cylodextrin Complexation Methods for Formulating Peptide Proteasome Inhibitors
UY34897A (es) 2012-07-09 2014-01-31 Onyx Therapeutics Inc Profarmacos de inhibidores peptidicos de expoxi cetona proteasa
WO2014011971A2 (en) * 2012-07-13 2014-01-16 Concert Pharmaceuticals, Inc. Deuterated carfilzomib
CA2879139C (en) 2012-07-18 2021-05-11 Onyx Therapeutics, Inc. Liposomal compositions of epoxyketone-based proteasome inhibitors
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