DK399789A - ANOTHER TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES, THEIR PREPARATION AND USE - Google Patents

ANOTHER TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES, THEIR PREPARATION AND USE Download PDF

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Publication number
DK399789A
DK399789A DK399789A DK399789A DK399789A DK 399789 A DK399789 A DK 399789A DK 399789 A DK399789 A DK 399789A DK 399789 A DK399789 A DK 399789A DK 399789 A DK399789 A DK 399789A
Authority
DK
Denmark
Prior art keywords
tetrahydropyridine
preparation
another
acetic acid
acid derivatives
Prior art date
Application number
DK399789A
Other languages
Danish (da)
Other versions
DK399789D0 (en
Inventor
Walter Loesel
Otto Roos
Gerd Schnorrenberg
Dietrich Arndts
Georg Speck
Ilse Streller
Werner Traunecker
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of DK399789D0 publication Critical patent/DK399789D0/en
Publication of DK399789A publication Critical patent/DK399789A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK399789A 1988-08-16 1989-08-15 ANOTHER TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES, THEIR PREPARATION AND USE DK399789A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3827727A DE3827727A1 (en) 1988-08-16 1988-08-16 ANALYZED TETRAHYDROPYRIDINE IGNESE DERIVATIVES, METHOD FOR THE PRODUCTION AND USE OF SUCH CONNECTIONS FOR CARDIRO PROTECTION

Publications (2)

Publication Number Publication Date
DK399789D0 DK399789D0 (en) 1989-08-15
DK399789A true DK399789A (en) 1990-02-17

Family

ID=6360928

Family Applications (1)

Application Number Title Priority Date Filing Date
DK399789A DK399789A (en) 1988-08-16 1989-08-15 ANOTHER TETRAHYDROPYRIDINE ACETIC ACID DERIVATIVES, THEIR PREPARATION AND USE

Country Status (16)

Country Link
EP (1) EP0358957A1 (en)
JP (1) JPH02160767A (en)
KR (1) KR900003129A (en)
AU (1) AU637767B2 (en)
DD (3) DD285595A5 (en)
DE (1) DE3827727A1 (en)
DK (1) DK399789A (en)
FI (1) FI893832A (en)
HU (1) HU208434B (en)
IL (1) IL91301A0 (en)
NO (1) NO893270L (en)
PH (1) PH27356A (en)
PL (1) PL161521B1 (en)
PT (1) PT91451A (en)
YU (1) YU160189A (en)
ZA (1) ZA896205B (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5162336A (en) * 1990-06-21 1992-11-10 Rhone-Poulenc Rorer Pharmaceuticals Inc. Tetrahydro-pyrido-indoles as cholecystokinin and gastrin antagonists
DE9017900U1 (en) * 1990-12-22 1993-01-28 Boehringer Ingelheim Kg, 6507 Ingelheim, De
DE4104257A1 (en) * 1991-02-13 1992-08-20 Boehringer Ingelheim Kg USE OF ANALYZED TETRAHYDROPYRIDINE IGNESE DERIVATIVES FOR THE TREATMENT OF NEUROLOGICAL ILLNESSES
US5643919A (en) * 1992-06-22 1997-07-01 Boehringer Ingelheim Kg Anellated dihydropyridines and the use thereof for the production of pharmaceutical preparation
KR100291706B1 (en) * 1992-06-22 2001-10-24 베링거 인겔하임 카게 Closed dihydropyridine, preparation method thereof and pharmaceutical composition comprising the same
EP0620222A3 (en) * 1993-04-14 1995-04-12 Lilly Co Eli Tetrahydro-beta-carbolines.
JPH09506880A (en) * 1993-12-21 1997-07-08 ベーリンガー インゲルハイム コマンディトゲゼルシャフト Annelated dihydropyridine and its use for preparing pharmaceutical formulations
DE4343683A1 (en) * 1993-12-21 1995-06-22 Boehringer Ingelheim Kg Anellated dihydropyridines and their use for the preparation of pharmaceutical preparations
DE4343641A1 (en) * 1993-12-21 1995-06-29 Boehringer Ingelheim Kg New fused di:hydro-pyridine derivs.
EP1159273A1 (en) 1999-03-02 2001-12-05 Boehringer Ingelheim Pharmaceuticals Inc. Compounds useful as reversible inhibitors of cathepsin s
US6420364B1 (en) 1999-09-13 2002-07-16 Boehringer Ingelheim Pharmaceuticals, Inc. Compound useful as reversible inhibitors of cysteine proteases
WO2003051869A1 (en) * 2001-12-19 2003-06-26 H. Lundbeck A/S 3,4-dihydro-1h-isoquinoloin-2-yl-derivatives
GB2422828A (en) * 2005-02-03 2006-08-09 Hunter Fleming Ltd Tricyclic cytoprotective compounds comprising an indole residue
NZ731621A (en) 2009-12-04 2019-01-25 Sunovion Pharmaceuticals Inc Multicyclic compounds and methods of use thereof
KR20190065246A (en) 2016-07-29 2019-06-11 선오비온 파마슈티컬스 인코포레이티드 Compounds and compositions and uses thereof
IL264446B1 (en) 2016-07-29 2024-05-01 Pgi Drug Discovery Llc Compounds and compositions and uses thereof
IL268694B2 (en) 2017-02-16 2023-10-01 Sunovion Pharmaceuticals Inc Treatment of schizophrenia
EP3661929B1 (en) 2017-08-02 2021-07-14 Sunovion Pharmaceuticals Inc. Isochroman compounds and uses thereof
WO2019161238A1 (en) 2018-02-16 2019-08-22 Sunovion Pharmaceuticals Inc. Salts, crystal forms, and production methods thereof
AU2020236225A1 (en) 2019-03-14 2021-09-16 Sunovion Pharmaceuticals Inc. Salts of a isochromanyl compound and crystalline forms, processes for preparing, therapeutic uses, and pharmaceutical compositions thereof
US11738002B2 (en) 2020-04-14 2023-08-29 Sunovion Pharmaceuticals Inc. Methods of treating neurological and psychiatric disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3021331A (en) * 1959-07-20 1962-02-13 Pfizer & Co C Azabenzopyridocolines
DE2361390A1 (en) * 1973-12-10 1975-06-19 Merck Patent Gmbh ISOCHINOLINE DERIVATIVES AND THE PROCESS FOR THEIR PRODUCTION
HU174697B (en) * 1976-12-30 1980-03-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new 6,7-dimethoxy-1,2,3,4-tetrahydro-1-isoquinolin-acetamide derivatives
FR2447921A1 (en) * 1979-02-05 1980-08-29 Synthelabo IMIDAZO AND PYRIMIDO-PYRIDO-INDOLES AND THEIR APPLICATION IN THERAPEUTICS
FR2455044A1 (en) * 1979-04-26 1980-11-21 Synthelabo PYRIDO-INDOLES AND THEIR APPLICATION IN THERAPEUTICS
DE3013906A1 (en) * 1980-04-11 1981-10-15 C.H. Boehringer Sohn, 6507 Ingelheim SUBSTITUTED (ALPHA) -AMINOCARBONYL-L-BENZYL-3,4-DIHYDRO-ISOCHINOLINE, METHOD FOR THE PRODUCTION AND USE THEREOF
DE3229215A1 (en) * 1982-08-05 1984-02-09 Basf Ag, 6700 Ludwigshafen 1- (HALOGENALKYL) -1,2,3,4-TETRAHYDRO-SS-CARBOLINE, THEIR PRODUCTION AND USE
DE3309596A1 (en) * 1982-08-05 1984-04-05 Basf Ag, 6700 Ludwigshafen 2-SUBSTITUTED 1- (3'-AMINOALKYL) -1,2,3,4-TETRAHYDRO-SS-CARBOLINE, THEIR PRODUCTION AND USE AS MEDICINAL PRODUCT
DE3621413A1 (en) * 1986-06-26 1988-01-07 Boehringer Ingelheim Kg USE OF CARBOCYCLIC AND HETEROCYCLICALLY FURNISHED DIHYDROPYRIDINE AS A CARDIOPROTECTIVE AGENT AND NEW HETEROCYCLIC AND CARBOCYCLICALLY FURNISHED DIHYDROPYRIDINE, METHOD FOR THE PRODUCTION THEREOF AND ITS ADDITIONAL PRODUCTS
IL86131A0 (en) * 1987-04-24 1988-11-15 Boehringer Ingelheim Kg Benzo-and thieno-3,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
AU3992589A (en) 1990-02-22
IL91301A0 (en) 1990-03-19
JPH02160767A (en) 1990-06-20
DD297640A5 (en) 1992-01-16
KR900003129A (en) 1990-03-23
EP0358957A1 (en) 1990-03-21
PT91451A (en) 1990-03-08
ZA896205B (en) 1991-04-24
DK399789D0 (en) 1989-08-15
HUT51277A (en) 1990-04-28
PL161521B1 (en) 1993-07-30
FI893832A (en) 1990-02-17
DD285595A5 (en) 1990-12-19
AU637767B2 (en) 1993-06-10
PH27356A (en) 1993-06-22
NO893270D0 (en) 1989-08-15
DD295379A5 (en) 1991-10-31
FI893832A0 (en) 1989-08-15
YU160189A (en) 1992-09-07
DE3827727A1 (en) 1990-02-22
HU208434B (en) 1993-10-28
NO893270L (en) 1990-02-19

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AHB Application shelved due to non-payment