DK3642331T3 - Fremgangsmåde til udvidelse af T-celler og anvendelser deraf - Google Patents
Fremgangsmåde til udvidelse af T-celler og anvendelser deraf Download PDFInfo
- Publication number
- DK3642331T3 DK3642331T3 DK18735229.9T DK18735229T DK3642331T3 DK 3642331 T3 DK3642331 T3 DK 3642331T3 DK 18735229 T DK18735229 T DK 18735229T DK 3642331 T3 DK3642331 T3 DK 3642331T3
- Authority
- DK
- Denmark
- Prior art keywords
- expanding
- cells
- Prior art date
Links
- 210000001744 T-lymphocyte Anatomy 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/461—Cellular immunotherapy characterised by the cell type used
- A61K39/4611—T-cells, e.g. tumor infiltrating lymphocytes [TIL], lymphokine-activated killer cells [LAK] or regulatory T cells [Treg]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/46—Cellular immunotherapy
- A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
- A61K39/4643—Vertebrate antigens
- A61K39/4644—Cancer antigens
- A61K39/464401—Neoantigens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K4/00—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof
- C07K4/12—Peptides having up to 20 amino acids in an undefined or only partially defined sequence; Derivatives thereof from animals; from humans
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/998—Proteins not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/11—Coculture with; Conditioned medium produced by blood or immune system cells
- C12N2502/1121—Dendritic cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2531/00—Microcarriers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Virology (AREA)
- Developmental Biology & Embryology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Fuel Cell (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1710023.1A GB201710023D0 (en) | 2017-06-22 | 2017-06-22 | T-cell expansion method and uses |
GBGB1716978.0A GB201716978D0 (en) | 2017-10-16 | 2017-10-16 | T-cell expansion method and uses |
PCT/EP2018/066690 WO2018234516A2 (en) | 2017-06-22 | 2018-06-21 | METHOD AND APPARATUS FOR EXPANSION OF T CELLULOCYTES |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3642331T3 true DK3642331T3 (da) | 2023-07-31 |
Family
ID=62784126
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK18735229.9T DK3642331T3 (da) | 2017-06-22 | 2018-06-21 | Fremgangsmåde til udvidelse af T-celler og anvendelser deraf |
Country Status (11)
Country | Link |
---|---|
US (1) | US20200140813A1 (da) |
EP (2) | EP4248980A3 (da) |
JP (1) | JP7218309B2 (da) |
KR (1) | KR20200020904A (da) |
CN (1) | CN110785487A (da) |
AU (1) | AU2018287169A1 (da) |
CA (1) | CA3068103A1 (da) |
DK (1) | DK3642331T3 (da) |
ES (1) | ES2950653T3 (da) |
FI (1) | FI3642331T3 (da) |
WO (1) | WO2018234516A2 (da) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111638329B (zh) * | 2020-06-09 | 2021-06-01 | 南方医科大学 | 一种用于检测布鲁氏菌病elispot检测试剂盒及其应用 |
EP4032973B1 (en) | 2021-01-21 | 2023-07-19 | Guizhou Sinorda Biotechnology CO., Ltd. | Modified t cells for adoptive immunotherapy |
AU2021395504A1 (en) | 2020-12-08 | 2023-06-29 | Guizhou Sinorda Biotechnology Co. Ltd. | Modified t cells for adoptive immunotherapy |
US20230092508A1 (en) * | 2021-09-20 | 2023-03-23 | Droplet Biosciences, Inc. | Methods for disease assessment using drain fluid |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200502391A (en) * | 2003-05-08 | 2005-01-16 | Xcyte Therapies Inc | Generation and isolation of antigen-specific t cells |
US20080171059A1 (en) * | 2006-08-07 | 2008-07-17 | Shanshan Wu Howland | Methods and compositions for increased priming of t-cells through cross-presentation of exogenous antigens |
US9107858B2 (en) * | 2007-12-05 | 2015-08-18 | Wisconsin Alumni Research Foundation | Dendritic cell targeting compositions and uses thereof |
CA2779601A1 (en) * | 2009-11-02 | 2011-05-05 | Orbis Health Solutions Llc | Vaccine compositions and methods of use |
WO2012159643A1 (en) * | 2011-05-24 | 2012-11-29 | Biontech Ag | Individualized vaccines for cancer |
AU2013351542B2 (en) * | 2012-11-28 | 2018-08-09 | BioNTech SE | Individualized vaccines for cancer |
EP2983702A2 (en) * | 2013-04-07 | 2016-02-17 | The Broad Institute, Inc. | Compositions and methods for personalized neoplasia vaccines |
AU2015314776A1 (en) * | 2014-09-14 | 2017-04-06 | Washington University | Personalized cancer vaccines and methods therefor |
JP6599450B2 (ja) * | 2014-10-02 | 2019-10-30 | アメリカ合衆国 | がん特異的突然変異に対し抗原特異性を有するt細胞を単離する方法 |
WO2016077215A2 (en) * | 2014-11-10 | 2016-05-19 | Yale University | Modular nanodevices for smart adaptable vaccines |
MY190974A (en) * | 2015-05-20 | 2022-05-25 | Massachusetts Gen Hospital | Shared neoantigens |
US11446390B2 (en) * | 2015-11-18 | 2022-09-20 | The University Of North Carolina At Chapel Hill | Antigen capturing nanoparticles for use in cancer immunotherapy |
ES2902477T3 (es) | 2015-12-04 | 2022-03-28 | Univ Texas | Péptidos SLC45A2 para inmunoterapia |
EP3182125A1 (en) * | 2015-12-16 | 2017-06-21 | Ab Tcer | T-cell reactivity platform |
-
2018
- 2018-06-21 CA CA3068103A patent/CA3068103A1/en active Pending
- 2018-06-21 WO PCT/EP2018/066690 patent/WO2018234516A2/en unknown
- 2018-06-21 EP EP23174945.8A patent/EP4248980A3/en active Pending
- 2018-06-21 JP JP2019570965A patent/JP7218309B2/ja active Active
- 2018-06-21 KR KR1020207002323A patent/KR20200020904A/ko not_active Application Discontinuation
- 2018-06-21 US US16/624,097 patent/US20200140813A1/en active Pending
- 2018-06-21 EP EP18735229.9A patent/EP3642331B1/en active Active
- 2018-06-21 DK DK18735229.9T patent/DK3642331T3/da active
- 2018-06-21 FI FIEP18735229.9T patent/FI3642331T3/fi active
- 2018-06-21 AU AU2018287169A patent/AU2018287169A1/en active Pending
- 2018-06-21 CN CN201880041920.4A patent/CN110785487A/zh active Pending
- 2018-06-21 ES ES18735229T patent/ES2950653T3/es active Active
Also Published As
Publication number | Publication date |
---|---|
US20200140813A1 (en) | 2020-05-07 |
CA3068103A1 (en) | 2018-12-27 |
EP4248980A3 (en) | 2023-12-06 |
JP2020524514A (ja) | 2020-08-20 |
EP3642331B1 (en) | 2023-05-24 |
FI3642331T3 (fi) | 2023-07-24 |
WO2018234516A3 (en) | 2019-02-14 |
WO2018234516A2 (en) | 2018-12-27 |
AU2018287169A1 (en) | 2020-01-16 |
EP4248980A2 (en) | 2023-09-27 |
EP3642331A2 (en) | 2020-04-29 |
KR20200020904A (ko) | 2020-02-26 |
JP7218309B2 (ja) | 2023-02-06 |
CN110785487A (zh) | 2020-02-11 |
ES2950653T3 (es) | 2023-10-11 |
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