DK3628049T3 - Tgf-beta-receptortype-ii-fusionsproteiner og anvendelser deraf - Google Patents

Tgf-beta-receptortype-ii-fusionsproteiner og anvendelser deraf Download PDF

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Publication number
DK3628049T3
DK3628049T3 DK18794202.4T DK18794202T DK3628049T3 DK 3628049 T3 DK3628049 T3 DK 3628049T3 DK 18794202 T DK18794202 T DK 18794202T DK 3628049 T3 DK3628049 T3 DK 3628049T3
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Denmark
Prior art keywords
tgf
fusion proteins
receptor type
beta receptor
beta
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DK18794202.4T
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English (en)
Inventor
Ravindra Kumar
Dianne S Sako
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Acceleron Pharma Inc
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
DK18794202.4T 2017-05-04 2018-05-03 Tgf-beta-receptortype-ii-fusionsproteiner og anvendelser deraf DK3628049T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201762501229P 2017-05-04 2017-05-04
US201762510422P 2017-05-24 2017-05-24
US201762578674P 2017-10-30 2017-10-30
PCT/US2018/030816 WO2018204594A1 (en) 2017-05-04 2018-05-03 Tgf-beta receptor type ii fusion proteins and uses thereof

Publications (1)

Publication Number Publication Date
DK3628049T3 true DK3628049T3 (da) 2023-08-14

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US (2) US11021527B2 (da)
EP (2) EP4241848A3 (da)
JP (2) JP7267664B2 (da)
KR (2) KR102635723B1 (da)
CN (1) CN110785431B (da)
AU (2) AU2018261131A1 (da)
BR (1) BR112019023071A2 (da)
CA (1) CA3061472A1 (da)
CY (1) CY1126121T1 (da)
DK (1) DK3628049T3 (da)
ES (1) ES2948647T3 (da)
FI (1) FI3628049T3 (da)
HR (1) HRP20230706T1 (da)
HU (1) HUE063840T2 (da)
LT (1) LT3628049T (da)
MD (1) MD3628049T2 (da)
PL (1) PL3628049T3 (da)
PT (1) PT3628049T (da)
RS (1) RS64315B1 (da)
SI (1) SI3628049T1 (da)
WO (1) WO2018204594A1 (da)

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CA3149810A1 (en) * 2019-08-15 2021-02-18 Nantbio, Inc. Tgf-beta trap
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CN114728072A (zh) 2019-10-23 2022-07-08 库尔生物制药有限公司 TGF-β多肽
WO2021092079A1 (en) * 2019-11-05 2021-05-14 Acceleron Pharma Inc. Treatments for systemic sclerosis
BR112022021785A2 (pt) * 2020-04-28 2022-12-06 Sinocelltech Ltd Molécula truncada de domínio extracelular tgfbr2, proteína de fusão de molécula truncada de domínio extracelular tgfbr2 e anticorpo anti-egfr e uso antitumoral de proteína de fusão
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Publication number Publication date
JP7267664B2 (ja) 2023-05-02
EP4241848A2 (en) 2023-09-13
FI3628049T3 (fi) 2023-07-26
RS64315B1 (sr) 2023-08-31
US20180327477A1 (en) 2018-11-15
PT3628049T (pt) 2023-07-03
CA3061472A1 (en) 2018-11-08
ES2948647T3 (es) 2023-09-15
AU2018261131A1 (en) 2019-11-07
SI3628049T1 (sl) 2023-10-30
HRP20230706T1 (hr) 2023-10-13
CN110785431A (zh) 2020-02-11
EP3628049A4 (en) 2021-01-13
MD3628049T2 (ro) 2023-10-31
JP2023055827A (ja) 2023-04-18
EP3628049A1 (en) 2020-04-01
HUE063840T2 (hu) 2024-02-28
EP4241848A3 (en) 2023-11-01
KR20240023201A (ko) 2024-02-20
AU2023200218A1 (en) 2023-02-16
WO2018204594A1 (en) 2018-11-08
PL3628049T3 (pl) 2023-09-25
CN110785431B (zh) 2024-05-07
KR102635723B1 (ko) 2024-02-08
JP2020518246A (ja) 2020-06-25
US11021527B2 (en) 2021-06-01
CY1126121T1 (el) 2023-11-15
LT3628049T (lt) 2023-08-25
US20210324040A1 (en) 2021-10-21
BR112019023071A2 (pt) 2020-06-09
EP3628049B1 (en) 2023-05-10
KR20200003873A (ko) 2020-01-10

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