DK3606909T3 - Natriumsalt af n-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1h-pyrazol-3-sulfonamid - Google Patents
Natriumsalt af n-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1h-pyrazol-3-sulfonamid Download PDFInfo
- Publication number
- DK3606909T3 DK3606909T3 DK19721230.1T DK19721230T DK3606909T3 DK 3606909 T3 DK3606909 T3 DK 3606909T3 DK 19721230 T DK19721230 T DK 19721230T DK 3606909 T3 DK3606909 T3 DK 3606909T3
- Authority
- DK
- Denmark
- Prior art keywords
- indacen
- hexahydro
- sulfonamide
- pyrazole
- carbamoyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Rheumatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB1806578.9A GB201806578D0 (en) | 2018-04-23 | 2018-04-23 | Novel compound |
PCT/EP2019/060311 WO2019206871A1 (en) | 2018-04-23 | 2019-04-23 | A sodium salt of n-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-1 -isopropyl-1 h-pyrazole-3-sulfonamide |
Publications (1)
Publication Number | Publication Date |
---|---|
DK3606909T3 true DK3606909T3 (da) | 2020-08-24 |
Family
ID=62236309
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK19721230.1T DK3606909T3 (da) | 2018-04-23 | 2019-04-23 | Natriumsalt af n-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-1-isopropyl-1h-pyrazol-3-sulfonamid |
Country Status (27)
Country | Link |
---|---|
US (2) | US10973803B2 (da) |
EP (2) | EP3606909B1 (da) |
JP (1) | JP7382958B2 (da) |
KR (1) | KR20210005589A (da) |
CN (1) | CN112020495B (da) |
AR (1) | AR114827A1 (da) |
AU (1) | AU2019257973A1 (da) |
BR (1) | BR112020021650A2 (da) |
CA (1) | CA3097832A1 (da) |
CY (1) | CY1123260T1 (da) |
DK (1) | DK3606909T3 (da) |
ES (1) | ES2811228T3 (da) |
GB (1) | GB201806578D0 (da) |
HR (1) | HRP20201263T1 (da) |
HU (1) | HUE050369T2 (da) |
LT (1) | LT3606909T (da) |
MA (2) | MA51082A (da) |
MD (1) | MD3606909T2 (da) |
ME (1) | ME03822B (da) |
MX (1) | MX2020011196A (da) |
PL (1) | PL3606909T3 (da) |
PT (1) | PT3606909T (da) |
RS (1) | RS60646B1 (da) |
SI (1) | SI3606909T1 (da) |
TW (1) | TW201943704A (da) |
UY (1) | UY38186A (da) |
WO (1) | WO2019206871A1 (da) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2018210525B2 (en) | 2017-01-23 | 2022-06-02 | Genentech, Inc. | Chemical compounds as inhibitors of interleukin-1 activity |
WO2018215818A1 (en) | 2017-05-24 | 2018-11-29 | The University Of Queensland | Novel compounds and uses |
EP3649112A1 (en) | 2017-07-07 | 2020-05-13 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as nlrp3 inhibitors |
US11926600B2 (en) | 2017-08-15 | 2024-03-12 | Inflazome Limited | Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors |
KR20200041337A (ko) | 2017-08-15 | 2020-04-21 | 인플라좀 리미티드 | 신규한 설폰아마이드 카복스아마이드 화합물 |
US11518739B2 (en) | 2017-08-15 | 2022-12-06 | Inflazome Limited | Sulfonamide carboxamide compounds |
BR112020003014A2 (pt) | 2017-08-15 | 2020-07-28 | Inflazome Limited | sulfonilureias e sulfoniltioureias como inibidores de vnlrp3 |
WO2019034692A1 (en) | 2017-08-15 | 2019-02-21 | Inflazome Limited | SULFONYLURATES AND SULFONYLTHIOURES AS INHIBITORS OF NLRP3 |
KR20200087759A (ko) | 2017-11-09 | 2020-07-21 | 인플라좀 리미티드 | 신규한 설폰아마이드 카복스아마이드 화합물 |
WO2019166628A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
WO2019166619A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
WO2019166629A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
US11834433B2 (en) | 2018-03-02 | 2023-12-05 | Inflazome Limited | Compounds |
WO2019166632A1 (en) | 2018-03-02 | 2019-09-06 | Inflazome Limited | Novel compounds |
GB201806578D0 (en) | 2018-04-23 | 2018-06-06 | Inflazome Ltd | Novel compound |
MA53170A (fr) | 2018-07-20 | 2021-05-26 | F Hoffmann La Roche Sa | Composés de sulfonylurée en tant qu'inhibiteurs de l'activité de l'interleukine 1 |
GB201817038D0 (en) | 2018-10-19 | 2018-12-05 | Inflazome Ltd | Novel processes |
GB201916237D0 (en) * | 2019-11-07 | 2019-12-25 | Inflazome Ltd | Novel treatment |
WO2021089776A1 (en) * | 2019-11-07 | 2021-05-14 | Inflazome Limited | Treatment and prevention of a traumatic brain disorder |
WO2021089769A1 (en) | 2019-11-07 | 2021-05-14 | Inflazome Limited | Treatment and prevention of neuroinflammation or an inflammatory brain disorder |
WO2021089781A1 (en) * | 2019-11-07 | 2021-05-14 | Inflazome Limited | Treatment or prevention of psychiatric brain disorders using the nlrp3 inhibitor n-((1,2,3,5,6,7-hexahydro-s-indacen-4-yl)carbamoyl)-1 -isopropyl-1 h-pyrazole-3-sulfonamide |
US20220401414A1 (en) * | 2019-11-07 | 2022-12-22 | Inflazome Limited | Treatment and prevention of a neurodegenerative disorder |
JP2023501334A (ja) * | 2019-11-07 | 2023-01-18 | インフレイゾーム リミテッド | 自己炎症性疾患の処置 |
WO2022023907A1 (en) | 2020-07-31 | 2022-02-03 | Novartis Ag | Methods of selecting and treating patients at elevated risk of major adverse cardiac events |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4802908A (en) * | 1987-01-22 | 1989-02-07 | E. I. Du Pont De Nemours And Company | Herbicidal 2-(1H)-pyrazinones |
BR0014003A (pt) * | 1999-09-14 | 2002-05-21 | Pfizer Prod Inc | Tratamento de combinação com compostos de diaril sufonil uréia e il-1ra |
JPWO2013031931A1 (ja) * | 2011-09-02 | 2015-03-23 | 協和発酵キリン株式会社 | ケモカイン受容体活性調節剤 |
IL253661B2 (en) * | 2015-02-16 | 2024-01-01 | Univ Queensland | Sulfonylureas bearing a pentagonal ring, pharmaceutical preparations and their uses |
FR3046933B1 (fr) | 2016-01-25 | 2018-03-02 | Galderma Research & Development | Inhibiteurs nlrp3 pour le traitement des pathologies cutanees inflammatoires |
WO2017140778A1 (en) | 2016-02-16 | 2017-08-24 | The University Of Queensland | Sulfonylureas and related compounds and use of same |
MA44729A (fr) | 2016-04-18 | 2021-05-12 | Novartis Ag | Composés et compositions pour traiter des états associés à une activité de nlrp |
AU2017253937B2 (en) | 2016-04-18 | 2021-08-05 | Novartis Ag | Compounds and compositions for treating conditions associated with NLRP activity |
EP3272739A1 (en) | 2016-07-20 | 2018-01-24 | NodThera Limited | Sulfonyl urea derivatives and their use in the control of interleukin-1 activity |
GB201806578D0 (en) | 2018-04-23 | 2018-06-06 | Inflazome Ltd | Novel compound |
GB201817038D0 (en) | 2018-10-19 | 2018-12-05 | Inflazome Ltd | Novel processes |
-
2018
- 2018-04-23 GB GBGB1806578.9A patent/GB201806578D0/en not_active Ceased
-
2019
- 2019-04-23 HU HUE19721230A patent/HUE050369T2/hu unknown
- 2019-04-23 CA CA3097832A patent/CA3097832A1/en active Pending
- 2019-04-23 BR BR112020021650-0A patent/BR112020021650A2/pt not_active Application Discontinuation
- 2019-04-23 RS RS20200936A patent/RS60646B1/sr unknown
- 2019-04-23 AR ARP190101056A patent/AR114827A1/es unknown
- 2019-04-23 MA MA051082A patent/MA51082A/fr unknown
- 2019-04-23 DK DK19721230.1T patent/DK3606909T3/da active
- 2019-04-23 PT PT197212301T patent/PT3606909T/pt unknown
- 2019-04-23 MD MDE20200181T patent/MD3606909T2/ro unknown
- 2019-04-23 EP EP19721230.1A patent/EP3606909B1/en active Active
- 2019-04-23 PL PL19721230T patent/PL3606909T3/pl unknown
- 2019-04-23 JP JP2020557902A patent/JP7382958B2/ja active Active
- 2019-04-23 WO PCT/EP2019/060311 patent/WO2019206871A1/en unknown
- 2019-04-23 ME MEP-2020-173A patent/ME03822B/me unknown
- 2019-04-23 TW TW108114167A patent/TW201943704A/zh unknown
- 2019-04-23 LT LTEP19721230.1T patent/LT3606909T/lt unknown
- 2019-04-23 CN CN201980026640.0A patent/CN112020495B/zh active Active
- 2019-04-23 MX MX2020011196A patent/MX2020011196A/es unknown
- 2019-04-23 UY UY0001038186A patent/UY38186A/es not_active Application Discontinuation
- 2019-04-23 AU AU2019257973A patent/AU2019257973A1/en not_active Abandoned
- 2019-04-23 SI SI201930005T patent/SI3606909T1/sl unknown
- 2019-04-23 ES ES19721230T patent/ES2811228T3/es active Active
- 2019-04-23 MA MA48051A patent/MA48051B1/fr unknown
- 2019-04-23 EP EP20176198.8A patent/EP3722281A1/en not_active Withdrawn
- 2019-04-23 KR KR1020207030023A patent/KR20210005589A/ko not_active Application Discontinuation
-
2020
- 2020-04-16 US US16/850,978 patent/US10973803B2/en active Active
- 2020-08-11 HR HRP20201263TT patent/HRP20201263T1/hr unknown
- 2020-08-12 CY CY20201100756T patent/CY1123260T1/el unknown
-
2021
- 2021-03-09 US US17/196,956 patent/US20210315862A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
MD3606909T2 (ro) | 2020-08-31 |
WO2019206871A1 (en) | 2019-10-31 |
LT3606909T (lt) | 2020-10-12 |
CN112020495B (zh) | 2024-05-17 |
AU2019257973A1 (en) | 2020-11-19 |
MA48051B1 (fr) | 2020-08-31 |
JP7382958B2 (ja) | 2023-11-17 |
JP2021522195A (ja) | 2021-08-30 |
UY38186A (es) | 2019-11-29 |
CA3097832A1 (en) | 2019-10-31 |
PL3606909T3 (pl) | 2020-11-16 |
EP3606909A1 (en) | 2020-02-12 |
US20210315862A1 (en) | 2021-10-14 |
BR112020021650A2 (pt) | 2021-01-26 |
CY1123260T1 (el) | 2021-12-31 |
MX2020011196A (es) | 2020-11-13 |
US10973803B2 (en) | 2021-04-13 |
RS60646B1 (sr) | 2020-09-30 |
HUE050369T2 (hu) | 2020-11-30 |
EP3722281A1 (en) | 2020-10-14 |
ME03822B (me) | 2021-04-20 |
HRP20201263T1 (hr) | 2021-02-05 |
KR20210005589A (ko) | 2021-01-14 |
US20200237723A1 (en) | 2020-07-30 |
GB201806578D0 (en) | 2018-06-06 |
MA51082A (fr) | 2021-05-19 |
CN112020495A (zh) | 2020-12-01 |
ES2811228T3 (es) | 2021-03-11 |
PT3606909T (pt) | 2020-07-09 |
TW201943704A (zh) | 2019-11-16 |
SI3606909T1 (sl) | 2020-09-30 |
EP3606909B1 (en) | 2020-05-27 |
AR114827A1 (es) | 2020-10-21 |
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