DK3533447T3 - Flydende bendamustinsammensætninger til anvendelse i fremgangsmåde til behandling af bendamustin-responsive tilstande hos patienter som kræver reducerede volumener til indgivelse - Google Patents

Flydende bendamustinsammensætninger til anvendelse i fremgangsmåde til behandling af bendamustin-responsive tilstande hos patienter som kræver reducerede volumener til indgivelse Download PDF

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Publication number
DK3533447T3
DK3533447T3 DK19151152.6T DK19151152T DK3533447T3 DK 3533447 T3 DK3533447 T3 DK 3533447T3 DK 19151152 T DK19151152 T DK 19151152T DK 3533447 T3 DK3533447 T3 DK 3533447T3
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Denmark
Prior art keywords
bendamustine
administration
treatment
methods
patients requiring
Prior art date
Application number
DK19151152.6T
Other languages
English (en)
Inventor
Srikanth Sundaram
Scott L Tarriff
Original Assignee
Eagle Pharmaceuticals Inc
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49212373&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK3533447(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Eagle Pharmaceuticals Inc filed Critical Eagle Pharmaceuticals Inc
Application granted granted Critical
Publication of DK3533447T3 publication Critical patent/DK3533447T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41641,3-Diazoles
    • A61K31/41841,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C07D235/12Radicals substituted by oxygen atoms

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
DK19151152.6T 2012-03-20 2013-03-15 Flydende bendamustinsammensætninger til anvendelse i fremgangsmåde til behandling af bendamustin-responsive tilstande hos patienter som kræver reducerede volumener til indgivelse DK3533447T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201261613173P 2012-03-20 2012-03-20
US201261669889P 2012-07-10 2012-07-10
US201261678715P 2012-08-02 2012-08-02
EP13765020.6A EP2827863B1 (en) 2012-03-20 2013-03-15 Liquid composition for use in a method of treating bendamustine-responsive conditions in patients requiring reduced volumes for administration

Publications (1)

Publication Number Publication Date
DK3533447T3 true DK3533447T3 (da) 2023-04-24

Family

ID=49212373

Family Applications (2)

Application Number Title Priority Date Filing Date
DK19151152.6T DK3533447T3 (da) 2012-03-20 2013-03-15 Flydende bendamustinsammensætninger til anvendelse i fremgangsmåde til behandling af bendamustin-responsive tilstande hos patienter som kræver reducerede volumener til indgivelse
DK13765020.6T DK2827863T3 (da) 2012-03-20 2013-03-15 Flydende sammensætning til anvendelse i en fremgangsmåde til behandling af bendamustin-responsive tilstande hos patienter der kræver reducerede volumener til indgivelse

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK13765020.6T DK2827863T3 (da) 2012-03-20 2013-03-15 Flydende sammensætning til anvendelse i en fremgangsmåde til behandling af bendamustin-responsive tilstande hos patienter der kræver reducerede volumener til indgivelse

Country Status (17)

Country Link
US (3) US9000021B2 (da)
EP (3) EP2827863B1 (da)
JP (6) JP6224064B2 (da)
CN (2) CN104271135B (da)
CA (1) CA2867343C (da)
DK (2) DK3533447T3 (da)
ES (2) ES2943668T3 (da)
FI (1) FI3533447T3 (da)
HK (1) HK1243346A1 (da)
HR (2) HRP20230276T1 (da)
HU (2) HUE044233T2 (da)
LT (1) LT2827863T (da)
PL (2) PL2827863T3 (da)
PT (2) PT2827863T (da)
RS (2) RS58744B1 (da)
SI (2) SI2827863T1 (da)
WO (1) WO2013142359A1 (da)

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* Cited by examiner, † Cited by third party
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PL3158991T3 (pl) 2010-01-28 2021-09-27 Eagle Pharmaceuticals, Inc. Preparaty bendamustyny
CN104271135B (zh) 2012-03-20 2017-05-17 赛多斯有限责任公司 在要求减少施用容量的患者中治疗苯达莫司汀响应性状况的方法
SI2827862T1 (sl) * 2012-03-20 2024-03-29 Eagle Pharmaceuticals, Inc. Formulacije bendamustina
US20230241218A1 (en) * 2012-07-10 2023-08-03 Eagle Pharmaceuticals, Inc. Formulations of bendamustine
US11826466B2 (en) 2016-08-31 2023-11-28 Navinta, Llc Bendamustine solution formulations
US10905677B2 (en) 2016-08-31 2021-02-02 Navinta, Llc Bendamustine solution formulations
US11730815B2 (en) * 2018-11-26 2023-08-22 Good Health, Llc Stable liquid pharmaceutical compositions comprising bendamustine
JP7235288B2 (ja) * 2019-01-07 2023-03-08 コーアイセイ株式会社 ベンダムスチンの液体製剤
CN110123747A (zh) * 2019-04-26 2019-08-16 嘉兴市爵拓科技有限公司 苯达莫司汀的制剂
JPWO2021014957A1 (da) * 2019-07-22 2021-01-28
WO2021161876A1 (ja) * 2020-02-10 2021-08-19 富士フイルム株式会社 ベンダムスチン液剤
US20240148696A1 (en) 2022-10-25 2024-05-09 Softkemo Pharma Inc. Lyophilized bendamustine-cyclodextrin composition

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Also Published As

Publication number Publication date
DK2827863T3 (da) 2019-04-23
HUE044233T2 (hu) 2019-10-28
ES2943668T3 (es) 2023-06-15
EP3533447A1 (en) 2019-09-04
PL3533447T3 (pl) 2023-07-17
JP2024037915A (ja) 2024-03-19
CA2867343A1 (en) 2013-09-26
JP2022028813A (ja) 2022-02-16
CA2867343C (en) 2020-08-11
US9579384B2 (en) 2017-02-28
SI2827863T1 (sl) 2019-06-28
RS58744B1 (sr) 2019-06-28
CN107157988A (zh) 2017-09-15
US20150080444A1 (en) 2015-03-19
US20150343061A1 (en) 2015-12-03
JP6224064B2 (ja) 2017-11-01
EP2827863B1 (en) 2019-01-16
FI3533447T3 (fi) 2023-05-04
HRP20230276T1 (hr) 2023-04-28
WO2013142359A1 (en) 2013-09-26
EP2827863A1 (en) 2015-01-28
JP6381761B2 (ja) 2018-08-29
CN104271135A (zh) 2015-01-07
US20130253026A1 (en) 2013-09-26
ES2718902T3 (es) 2019-07-05
JP2015510940A (ja) 2015-04-13
PL2827863T3 (pl) 2019-07-31
EP2827863A4 (en) 2015-11-18
US9000021B2 (en) 2015-04-07
PT2827863T (pt) 2019-05-13
JP2020143143A (ja) 2020-09-10
PT3533447T (pt) 2023-05-17
JP2018197248A (ja) 2018-12-13
HK1243346A1 (zh) 2018-07-13
CN104271135B (zh) 2017-05-17
RS64137B1 (sr) 2023-05-31
SI3533447T1 (sl) 2023-06-30
EP3533447B1 (en) 2023-03-15
HUE062230T2 (hu) 2023-10-28
JP2018048153A (ja) 2018-03-29
EP4218756A1 (en) 2023-08-02
JP6738376B2 (ja) 2020-08-12
HRP20190693T1 (hr) 2019-10-04
LT2827863T (lt) 2019-06-10

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