DK3040336T3 - Forbindelser til brug i behandling af TYK2 Kinase-medierede tilstande - Google Patents
Forbindelser til brug i behandling af TYK2 Kinase-medierede tilstande Download PDFInfo
- Publication number
- DK3040336T3 DK3040336T3 DK16150956.7T DK16150956T DK3040336T3 DK 3040336 T3 DK3040336 T3 DK 3040336T3 DK 16150956 T DK16150956 T DK 16150956T DK 3040336 T3 DK3040336 T3 DK 3040336T3
- Authority
- DK
- Denmark
- Prior art keywords
- compounds
- treatment
- mediated conditions
- tyk2 kinase
- tyk2
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261605952P | 2012-03-02 | 2012-03-02 | |
| EP13157419.6A EP2634185B1 (en) | 2012-03-02 | 2013-03-01 | TYK2 kinase inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK3040336T3 true DK3040336T3 (da) | 2020-06-22 |
Family
ID=47754367
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK16150956.7T DK3040336T3 (da) | 2012-03-02 | 2013-03-01 | Forbindelser til brug i behandling af TYK2 Kinase-medierede tilstande |
| DK13157419.6T DK2634185T3 (da) | 2012-03-02 | 2013-03-01 | TYK2-kinasehæmmere |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK13157419.6T DK2634185T3 (da) | 2012-03-02 | 2013-03-01 | TYK2-kinasehæmmere |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US20130231340A1 (da) |
| EP (2) | EP2634185B1 (da) |
| DK (2) | DK3040336T3 (da) |
| ES (1) | ES2566205T3 (da) |
| PL (1) | PL2634185T3 (da) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB201202027D0 (en) | 2012-02-06 | 2012-03-21 | Sareum Ltd | Pharmaceutical compounds |
| DK3040336T3 (da) | 2012-03-02 | 2020-06-22 | Sareum Ltd | Forbindelser til brug i behandling af TYK2 Kinase-medierede tilstande |
| MX369974B (es) * | 2013-09-03 | 2019-11-27 | Sareum Ltd | Compuestos farmaceuticos. |
| GB201617871D0 (en) | 2016-10-21 | 2016-12-07 | Sareum Limited | Pharmaceutical compounds |
| EP3551034A1 (en) | 2016-12-07 | 2019-10-16 | Progenity, Inc. | Gastrointestinal tract detection methods, devices and systems |
| US11033490B2 (en) | 2016-12-14 | 2021-06-15 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a JAK inhibitor and devices |
| EP4338802A2 (en) | 2017-03-08 | 2024-03-20 | Takeda Pharmaceutical Company Limited | Tyk2 inhibitors, uses, and methods for production thereof |
| US11372003B2 (en) * | 2018-04-13 | 2022-06-28 | Incyte Corporation | Biomarkers for graft-versus-host disease |
| EP3810094A1 (en) | 2018-06-20 | 2021-04-28 | Progenity, Inc. | Treatment of a disease of the gastrointestinal tract with a jak or other kinase inhibitor |
| GB201816369D0 (en) * | 2018-10-08 | 2018-11-28 | Sareum Ltd | Pharmaceutical compounds |
| US20230107927A1 (en) | 2020-02-28 | 2023-04-06 | First Wave Bio, Inc. | Methods of treating iatrogenic autoimmune colitis |
| GB202005114D0 (en) | 2020-04-07 | 2020-05-20 | Sareum Ltd | Crystalline Forms of a Pharmaceutical Compound |
| EP3944859A1 (en) | 2020-07-30 | 2022-02-02 | Assistance Publique Hôpitaux de Paris | Method for treating immune toxicities induced by immune checkpoint inhibitors |
| CA3236262A1 (en) | 2021-10-25 | 2023-05-04 | Isaac Marx | Tyk2 degraders and uses thereof |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE794096A (fr) | 1972-08-07 | 1973-05-16 | Lepetit Spa | Oxazoles 2,4,5-trisubstitues et leur preparation |
| GB1497536A (en) | 1973-12-17 | 1978-01-12 | Lilly Industries Ltd | 2-acylaminooxazoles methods for their preparation and their use |
| JPS56159794A (en) | 1980-05-12 | 1981-12-09 | Tokyo Optical | Length or angle measuring device |
| JPH0753716B2 (ja) | 1986-07-02 | 1995-06-07 | 吉富製薬株式会社 | イミダゾ−ルカルボキサミド誘導体 |
| DE19653355A1 (de) | 1996-12-20 | 1998-06-25 | Dresden Arzneimittel | Neue, antikonvulsiv wirkende Aminoimidazole und Verfahren zu ihrer Herstellung |
| GB0003154D0 (en) | 2000-02-12 | 2000-04-05 | Astrazeneca Uk Ltd | Novel compounds |
| DE60133897D1 (de) | 2000-06-28 | 2008-06-19 | Astrazeneca Ab | Substituierte chinazolin-derivate und deren verwendung als aurora-2-kinase inhibitoren |
| DK1392291T3 (da) | 2000-10-30 | 2007-10-08 | Janssen Pharmaceutica Nv | Tripeptidylpeptidaseinhibitorer |
| US7361665B2 (en) | 2002-07-09 | 2008-04-22 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-Jun N-terminal kinases (JNK) and other protein kinases |
| PL1684750T3 (pl) | 2003-10-23 | 2010-10-29 | Ab Science | 2-Aminoarylooksazole jako inhibitory kinazy tyrozynowej |
| GB0504753D0 (en) | 2005-03-08 | 2005-04-13 | Astrazeneca Ab | Chemical compounds |
| EP1932833B1 (en) | 2005-10-07 | 2012-08-01 | Kissei Pharmaceutical Co., Ltd. | Nitrogenated heterocyclic compound and pharmaceutical composition comprising the same |
| DK200600313A (da) | 2006-03-03 | 2006-03-13 | Novo Nordisk As | Treating type 2 diabetes or metabolic syndrome with an interleukin 1beta inhibitor or an interleukin 1beta synthesis or release inhibitor |
| US8080669B2 (en) | 2006-05-12 | 2011-12-20 | Ab Science | Process for the synthesis of 2-aminoxazole compounds |
| US20090093452A1 (en) | 2006-08-24 | 2009-04-09 | Pfizer Inc. | Pyrrole, Thiophene, Furan, Imidazole, Oxazole, and Thiazole Derivatives |
| GB0709031D0 (en) | 2007-05-10 | 2007-06-20 | Sareum Ltd | Pharmaceutical compounds |
| JP5478488B2 (ja) | 2007-06-20 | 2014-04-23 | メルク・シャープ・アンド・ドーム・コーポレーション | Ｊａｎｕｓキナーゼの阻害剤 |
| CA2719847A1 (en) | 2008-04-21 | 2010-01-28 | Merck Sharp & Dohme Corp. | Inhibitors of janus kinases |
| EP2299816B1 (en) | 2008-06-18 | 2013-11-13 | Merck Sharp & Dohme Corp. | Inhibitors of janus kinases |
| EP2310384B1 (en) | 2008-07-09 | 2014-04-09 | Merck Sharp & Dohme Corp. | Inhibitors of janus kinases |
| EP2166006A1 (en) | 2008-09-18 | 2010-03-24 | Dompe' S.P.A. | 2-aryl-propionic acids and derivatives and pharmaceutical compositions containing them |
| GB0820819D0 (en) | 2008-11-13 | 2008-12-24 | Sareum Ltd | Pharmaceutical compounds |
| CN102869359A (zh) | 2010-03-17 | 2013-01-09 | 弗·哈夫曼-拉罗切有限公司 | 咪唑并吡啶和嘌呤化合物、组合物和使用方法 |
| WO2012000970A1 (en) | 2010-07-01 | 2012-01-05 | Cellzome Limited | Triazolopyridines as tyk2 inhibitors |
| WO2012021611A1 (en) * | 2010-08-11 | 2012-02-16 | Millennium Pharmaceuticals, Inc. | Heteroaryls and uses thereof |
| MX2014004473A (es) | 2011-10-12 | 2015-04-14 | Array Biopharma Inc | Imidazo [1,2-c] pirimidinas 5,7-substituidas. |
| DK3040336T3 (da) * | 2012-03-02 | 2020-06-22 | Sareum Ltd | Forbindelser til brug i behandling af TYK2 Kinase-medierede tilstande |
| GB201617871D0 (en) * | 2016-10-21 | 2016-12-07 | Sareum Limited | Pharmaceutical compounds |
-
2013
- 2013-03-01 DK DK16150956.7T patent/DK3040336T3/da active
- 2013-03-01 PL PL13157419T patent/PL2634185T3/pl unknown
- 2013-03-01 DK DK13157419.6T patent/DK2634185T3/da active
- 2013-03-01 EP EP13157419.6A patent/EP2634185B1/en active Active
- 2013-03-01 US US13/781,902 patent/US20130231340A1/en not_active Abandoned
- 2013-03-01 EP EP16150956.7A patent/EP3040336B1/en active Active
- 2013-03-01 ES ES13157419.6T patent/ES2566205T3/es active Active
-
2019
- 2019-03-13 US US16/351,620 patent/US10882829B2/en active Active
-
2020
- 2020-12-01 US US17/108,266 patent/US11673870B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2634185A1 (en) | 2013-09-04 |
| US11673870B2 (en) | 2023-06-13 |
| US20190210983A1 (en) | 2019-07-11 |
| EP3040336B1 (en) | 2020-04-08 |
| DK2634185T3 (da) | 2016-03-21 |
| US10882829B2 (en) | 2021-01-05 |
| EP2634185B1 (en) | 2016-01-13 |
| PL2634185T3 (pl) | 2016-06-30 |
| US20210087154A1 (en) | 2021-03-25 |
| EP3040336A1 (en) | 2016-07-06 |
| US20130231340A1 (en) | 2013-09-05 |
| ES2566205T3 (es) | 2016-04-11 |
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