DK3412664T3 - Heterocyklisk sulfonamidderivat og medicin indeholdende samme - Google Patents

Heterocyklisk sulfonamidderivat og medicin indeholdende samme Download PDF

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Publication number
DK3412664T3
DK3412664T3 DK17747613.2T DK17747613T DK3412664T3 DK 3412664 T3 DK3412664 T3 DK 3412664T3 DK 17747613 T DK17747613 T DK 17747613T DK 3412664 T3 DK3412664 T3 DK 3412664T3
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DK
Denmark
Prior art keywords
sulfonide
heterocyclic
derivative
same
medicine containing
Prior art date
Application number
DK17747613.2T
Other languages
English (en)
Inventor
Kaori Kobayashi
Tamotsu Suzuki
Tatsuya Okuzumi
Original Assignee
Ea Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ea Pharma Co Ltd filed Critical Ea Pharma Co Ltd
Application granted granted Critical
Publication of DK3412664T3 publication Critical patent/DK3412664T3/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D491/00Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04Ortho-condensed systems
    • C07D491/044Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
DK17747613.2T 2016-02-05 2017-02-03 Heterocyklisk sulfonamidderivat og medicin indeholdende samme DK3412664T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016021358 2016-02-05
PCT/JP2017/004134 WO2017135462A1 (ja) 2016-02-05 2017-02-03 複素環スルホンアミド誘導体及びそれを含有する医薬

Publications (1)

Publication Number Publication Date
DK3412664T3 true DK3412664T3 (da) 2022-06-07

Family

ID=59499709

Family Applications (1)

Application Number Title Priority Date Filing Date
DK17747613.2T DK3412664T3 (da) 2016-02-05 2017-02-03 Heterocyklisk sulfonamidderivat og medicin indeholdende samme

Country Status (15)

Country Link
US (1) US10584116B2 (da)
EP (1) EP3412664B1 (da)
JP (1) JP6906449B2 (da)
KR (1) KR20180104150A (da)
CN (1) CN108602807B (da)
AU (1) AU2017213993B2 (da)
BR (1) BR112018015851A2 (da)
CA (1) CA3012812A1 (da)
DK (1) DK3412664T3 (da)
EA (1) EA037264B1 (da)
ES (1) ES2911416T3 (da)
MA (1) MA43978A (da)
MX (1) MX2018009458A (da)
PL (1) PL3412664T3 (da)
WO (1) WO2017135462A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3487853B1 (en) * 2016-07-20 2022-06-08 F. Hoffmann-La Roche AG Bicyclic proline compounds
FR3114235A1 (fr) 2020-09-18 2022-03-25 Université Grenoble Alpes Inhibition du canal trpa1 astrocytaire comme nouvelle cible therapeutique neuroprotectrice dans les phases prodromales de la maladie d’alzheimer
IT202100015098A1 (it) 2021-06-09 2022-12-09 Flonext S R L Composto antagonista del canale trpa1 per uso in patologie degenerative della retina
WO2023033097A1 (ja) * 2021-09-02 2023-03-09 Eaファーマ株式会社 複素環スルホンアミド誘導体の製造方法、およびその合成中間体

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8017612B2 (en) * 2006-04-18 2011-09-13 Japan Tobacco Inc. Piperazine compound and use thereof as a HCV polymerase inhibitor
US8614201B2 (en) 2009-06-05 2013-12-24 Janssen Pharmaceutica Nv Heterocyclic amides as modulators of TRPA1
EP2520566A1 (en) * 2011-05-06 2012-11-07 Orion Corporation New Pharmaceutical Compounds
EP2805718B1 (en) 2012-01-17 2018-04-04 EA Pharma Co., Ltd. Heterocyclic amide derivative and pharmaceutical product containing same
WO2014049047A1 (en) 2012-09-27 2014-04-03 F. Hoffmann-La Roche Ag Substituted sulfonamide compounds
CN104854086B (zh) * 2012-12-18 2017-06-27 Ea制药株式会社 杂环酰胺衍生物和含有其的药物
EP2774919A1 (en) 2013-03-06 2014-09-10 Pharmeste S.R.L. In Liquidazione Novel sulfonamide TRPA1 receptor antagonists
BR112016002012A2 (pt) * 2013-10-11 2017-08-01 Hoffmann La Roche compostos de sulfonamida heterocíclica substituída úteis como moduladores de trpa1
MX2016009794A (es) * 2014-01-28 2017-01-13 Ea Pharma Co Ltd Derivado de sulfonamida heterociclico y medicina que comprende el mismo.
SG11201706451TA (en) * 2015-02-15 2017-09-28 Hoffmann La Roche 1-(het)arylsulfonyl-(pyrrolidine or piperidine)-2-carboxamide derivatives and their use as trpa1 antagonists
CN107849029A (zh) 2015-07-29 2018-03-27 Ea制药株式会社 环丙烷衍生物及含有其的药物

Also Published As

Publication number Publication date
AU2017213993B2 (en) 2021-03-25
KR20180104150A (ko) 2018-09-19
US20190023699A1 (en) 2019-01-24
EA037264B1 (ru) 2021-03-01
EP3412664A1 (en) 2018-12-12
JPWO2017135462A1 (ja) 2018-12-13
EA201891782A1 (ru) 2019-06-28
AU2017213993A1 (en) 2018-09-13
PL3412664T3 (pl) 2022-06-06
ES2911416T3 (es) 2022-05-19
EP3412664A4 (en) 2019-10-16
JP6906449B2 (ja) 2021-07-21
MA43978A (fr) 2018-12-12
CN108602807A (zh) 2018-09-28
WO2017135462A1 (ja) 2017-08-10
MX2018009458A (es) 2018-09-21
EP3412664B1 (en) 2022-03-30
US10584116B2 (en) 2020-03-10
CN108602807B (zh) 2022-05-13
CA3012812A1 (en) 2017-08-10
BR112018015851A2 (pt) 2018-12-26

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