US6040166A
(en)
|
1985-03-28 |
2000-03-21 |
Roche Molecular Systems, Inc. |
Kits for amplifying and detecting nucleic acid sequences, including a probe
|
US4822731A
(en)
|
1986-01-09 |
1989-04-18 |
Cetus Corporation |
Process for labeling single-stranded nucleic acids and hybridizaiton probes
|
US5047519A
(en)
|
1986-07-02 |
1991-09-10 |
E. I. Du Pont De Nemours And Company |
Alkynylamino-nucleotides
|
EP0260032B1
(de)
|
1986-09-08 |
1994-01-26 |
Ajinomoto Co., Inc. |
Verbindungen zur Spaltung von RNS an eine spezifische Position, Oligomere, verwendet bei der Herstellung dieser Verbindungen und Ausgangsprodukte für die Synthese dieser Oligomere
|
US5449602A
(en)
|
1988-01-13 |
1995-09-12 |
Amoco Corporation |
Template-directed photoligation
|
US5025388A
(en)
|
1988-08-26 |
1991-06-18 |
Cramer Richard D Iii |
Comparative molecular field analysis (CoMFA)
|
US5849482A
(en)
*
|
1988-09-28 |
1998-12-15 |
Epoch Pharmaceuticals, Inc. |
Crosslinking oligonucleotides
|
AU649217B2
(en)
|
1988-11-18 |
1994-05-19 |
Regents Of The University Of California, The |
Method for site-specifically incorporating unnatural amino acids into proteins
|
US5324829A
(en)
|
1988-12-16 |
1994-06-28 |
Ortho Diagnostic Systems, Inc. |
High specific activity nucleic acid probes having target recognition and signal generating moieties
|
DK0494955T3
(da)
|
1989-10-05 |
1998-10-26 |
Optein Inc |
Cellefri syntese og isolering af hidtil ukendte gener og polypeptider
|
US6005087A
(en)
|
1995-06-06 |
1999-12-21 |
Isis Pharmaceuticals, Inc. |
2'-modified oligonucleotides
|
US5646265A
(en)
|
1990-01-11 |
1997-07-08 |
Isis Pharmceuticals, Inc. |
Process for the preparation of 2'-O-alkyl purine phosphoramidites
|
US5670633A
(en)
|
1990-01-11 |
1997-09-23 |
Isis Pharmaceuticals, Inc. |
Sugar modified oligonucleotides that detect and modulate gene expression
|
CA2039517C
(en)
|
1990-04-03 |
2006-11-07 |
David Segev |
Dna probe signal amplification
|
US5723289A
(en)
|
1990-06-11 |
1998-03-03 |
Nexstar Pharmaceuticals, Inc. |
Parallel selex
|
US5723286A
(en)
|
1990-06-20 |
1998-03-03 |
Affymax Technologies N.V. |
Peptide library and screening systems
|
US5650489A
(en)
|
1990-07-02 |
1997-07-22 |
The Arizona Board Of Regents |
Random bio-oligomer library, a method of synthesis thereof, and a method of use thereof
|
AU8498091A
(en)
|
1990-08-02 |
1992-03-02 |
Regents Of The University Of Colorado, The |
Systematic polypeptide evolution by reverse translation
|
US5843701A
(en)
|
1990-08-02 |
1998-12-01 |
Nexstar Pharmaceticals, Inc. |
Systematic polypeptide evolution by reverse translation
|
US5432272A
(en)
|
1990-10-09 |
1995-07-11 |
Benner; Steven A. |
Method for incorporating into a DNA or RNA oligonucleotide using nucleotides bearing heterocyclic bases
|
AU2313392A
(en)
|
1991-08-01 |
1993-03-02 |
University Research Corporation |
Systematic polypeptide evolution by reverse translation
|
US5474796A
(en)
|
1991-09-04 |
1995-12-12 |
Protogene Laboratories, Inc. |
Method and apparatus for conducting an array of chemical reactions on a support surface
|
JP2780572B2
(ja)
|
1991-09-13 |
1998-07-30 |
株式会社島津製作所 |
オリゴヌクレオチドの酵素的合成法及びオリゴヌクレオチドのプライマーとしての使用
|
US5639603A
(en)
|
1991-09-18 |
1997-06-17 |
Affymax Technologies N.V. |
Synthesizing and screening molecular diversity
|
DE69217497T2
(de)
|
1991-09-18 |
1997-06-12 |
Affymax Tech Nv |
Verfahren zur synthese der verschiedenen sammlungen von oligomeren
|
US6197556B1
(en)
|
1991-12-20 |
2001-03-06 |
The University Of Chicago |
Nucleic acid amplification using modular branched primers
|
US5424413A
(en)
|
1992-01-22 |
1995-06-13 |
Gen-Probe Incorporated |
Branched nucleic acid probes
|
US5573905A
(en)
|
1992-03-30 |
1996-11-12 |
The Scripps Research Institute |
Encoded combinatorial chemical libraries
|
US5541061A
(en)
|
1992-04-29 |
1996-07-30 |
Affymax Technologies N.V. |
Methods for screening factorial chemical libraries
|
US5565324A
(en)
|
1992-10-01 |
1996-10-15 |
The Trustees Of Columbia University In The City Of New York |
Complex combinatorial chemical libraries encoded with tags
|
US6503759B1
(en)
|
1992-10-01 |
2003-01-07 |
The Trustees Of Columbia University In The City Of New York |
Complex combinatorial chemical libraries encoded with tags
|
AU686579B2
(en)
|
1992-10-01 |
1998-02-12 |
Cold Spring Harbor Laboratory |
Complex combinatorial chemical libraries encoded with tags
|
US5684169A
(en)
|
1992-11-27 |
1997-11-04 |
Ensuiko Sugar Refining Co., Ltd. |
Cyclodextrin inclusion complex of taxol, and method for its production and its use
|
JPH08504444A
(ja)
|
1992-12-11 |
1996-05-14 |
カイロン コーポレイション |
コードされるポリマーの合成
|
DE4244584A1
(de)
*
|
1992-12-28 |
1994-07-07 |
Krone Ag |
Verfahren und Anordnung zur Vernetzung von elektro-optischen Bildwandmodulen
|
US5681943A
(en)
|
1993-04-12 |
1997-10-28 |
Northwestern University |
Method for covalently linking adjacent oligonucleotides
|
ES2204913T3
(es)
|
1993-04-12 |
2004-05-01 |
Northwestern University |
Metodo para formacion de oligonucleotidos.
|
US5840485A
(en)
|
1993-05-27 |
1998-11-24 |
Selectide Corporation |
Topologically segregated, encoded solid phase libraries
|
CA2163637C
(en)
|
1993-05-27 |
2008-05-06 |
Michal Lebl |
Topologically segregated, encoded solid phase libraries
|
US5473060A
(en)
|
1993-07-02 |
1995-12-05 |
Lynx Therapeutics, Inc. |
Oligonucleotide clamps having diagnostic applications
|
JPH09500378A
(ja)
|
1993-07-02 |
1997-01-14 |
リンクス セラピューティクス,インコーポレイティド |
枝分れされそして複雑に結合された高分子構造体の集中的合成
|
US5571903A
(en)
|
1993-07-09 |
1996-11-05 |
Lynx Therapeutics, Inc. |
Auto-ligating oligonucleotide compounds
|
US6087186A
(en)
|
1993-07-16 |
2000-07-11 |
Irori |
Methods and apparatus for synthesizing labeled combinatorial chemistry libraries
|
GB9315847D0
(en)
|
1993-07-30 |
1993-09-15 |
Isis Innovation |
Tag reagent and assay method
|
DK96093D0
(da)
|
1993-08-25 |
1993-08-25 |
Symbicom Ab |
Improvements in molecular modelling and drug design
|
CN1154640C
(zh)
|
1993-10-01 |
2004-06-23 |
纽约市哥伦比亚大学理事 |
用标示物编码的多元组合化学库
|
US6165778A
(en)
|
1993-11-02 |
2000-12-26 |
Affymax Technologies N.V. |
Reaction vessel agitation apparatus
|
NZ276860A
(en)
|
1993-11-02 |
1997-09-22 |
Affymax Tech Nv |
Apparatus and its use for synthesising diverse molecular products on substrates
|
US5503805A
(en)
|
1993-11-02 |
1996-04-02 |
Affymax Technologies N.V. |
Apparatus and method for parallel coupling reactions
|
EP0736103A4
(de)
|
1993-12-17 |
1999-07-28 |
Roger S Cubicciotti |
Auf nukleotide gerichtete zusammenstellung von bimolekularen und multimolekularen medikamenten vorrichtungen
|
EP0739486A4
(de)
|
1994-01-13 |
1998-09-09 |
Univ Columbia |
Synthetische rezeptoren, bibliotheken und ihre verwendung
|
US5605793A
(en)
|
1994-02-17 |
1997-02-25 |
Affymax Technologies N.V. |
Methods for in vitro recombination
|
US5449613A
(en)
|
1994-03-01 |
1995-09-12 |
The University Of Iowa Research Foundation |
Reacting an enzyme in a non-aqueous solvent by adding a lyophilizate of enzyme and salt to the solvent
|
US6936477B2
(en)
|
1994-04-13 |
2005-08-30 |
The Trustees Of Columbia University In The City Of New York |
Complex combinatorial chemical libraries encoded with tags
|
US5643722A
(en)
|
1994-05-11 |
1997-07-01 |
Trustees Of Boston University |
Methods for the detection and isolation of proteins
|
JPH08268A
(ja)
|
1994-06-16 |
1996-01-09 |
Koichi Nishigaki |
連結した2本鎖dnaの製造方法
|
US5663046A
(en)
|
1994-06-22 |
1997-09-02 |
Pharmacopeia, Inc. |
Synthesis of combinatorial libraries
|
CA2193228A1
(en)
|
1994-06-23 |
1996-01-04 |
Christopher Holmes |
Photolabile compounds and methods for their use
|
MX9700725A
(es)
|
1994-07-26 |
1997-05-31 |
Scripps Research Inst |
Coleccion combinatoria soluble.
|
US5604097A
(en)
|
1994-10-13 |
1997-02-18 |
Spectragen, Inc. |
Methods for sorting polynucleotides using oligonucleotide tags
|
US5846719A
(en)
|
1994-10-13 |
1998-12-08 |
Lynx Therapeutics, Inc. |
Oligonucleotide tags for sorting and identification
|
US5695934A
(en)
|
1994-10-13 |
1997-12-09 |
Lynx Therapeutics, Inc. |
Massively parallel sequencing of sorted polynucleotides
|
US6045671A
(en)
|
1994-10-18 |
2000-04-04 |
Symyx Technologies, Inc. |
Systems and methods for the combinatorial synthesis of novel materials
|
US5985356A
(en)
|
1994-10-18 |
1999-11-16 |
The Regents Of The University Of California |
Combinatorial synthesis of novel materials
|
WO1997027317A1
(en)
|
1996-01-23 |
1997-07-31 |
Affymetrix, Inc. |
Nucleic acid analysis techniques
|
WO1996024847A1
(en)
|
1995-02-10 |
1996-08-15 |
Smithkline Beecham Corporation |
A process for identifiying pharmaceutically active agents using an epitope-tagged library
|
US5843650A
(en)
|
1995-05-01 |
1998-12-01 |
Segev; David |
Nucleic acid detection and amplification by chemical linkage of oligonucleotides
|
US5679519A
(en)
|
1995-05-09 |
1997-10-21 |
Oprandy; John J. |
Multi-label complex for enhanced sensitivity in electrochemiluminescence assay
|
US6210900B1
(en)
|
1995-05-23 |
2001-04-03 |
Smithkline Beecham Corporation |
Method of encoding a series of combinatorial libraries and developing structure activity relationships
|
US5830658A
(en)
|
1995-05-31 |
1998-11-03 |
Lynx Therapeutics, Inc. |
Convergent synthesis of branched and multiply connected macromolecular structures
|
US5824471A
(en)
|
1995-06-05 |
1998-10-20 |
Brigham And Women's Hospital |
Detection of mismatches by cleavage of nucleic acid heteroduplexes
|
US5910408A
(en)
*
|
1995-06-07 |
1999-06-08 |
The General Hospital Corporation |
Catalytic DNA having ligase activity
|
US5958792A
(en)
|
1995-06-07 |
1999-09-28 |
Chiron Corporation |
Combinatorial libraries of substrate-bound cyclic organic compounds
|
HUP9900910A2
(hu)
|
1995-06-07 |
1999-07-28 |
Lynx Therapeutics, Inc. |
Oligonukleotid jelzések osztályozáshoz és azonosításhoz
|
WO1997004131A1
(en)
|
1995-07-21 |
1997-02-06 |
Forsyth Dental Infirmary For Children |
Single primer amplification of polynucleotide hairpins
|
US5780613A
(en)
|
1995-08-01 |
1998-07-14 |
Northwestern University |
Covalent lock for self-assembled oligonucleotide constructs
|
US5795976A
(en)
|
1995-08-08 |
1998-08-18 |
The Board Of Trustees Of The Leland Stanford Junior University |
Detection of nucleic acid heteroduplex molecules by denaturing high-performance liquid chromatography and methods for comparative sequencing
|
US5723320A
(en)
|
1995-08-29 |
1998-03-03 |
Dehlinger; Peter J. |
Position-addressable polynucleotide arrays
|
AU7247896A
(en)
|
1995-09-29 |
1997-04-17 |
Scripps Research Institute, The |
Protein signature analysis
|
DE19646372C1
(de)
|
1995-11-11 |
1997-06-19 |
Evotec Biosystems Gmbh |
Genotyp und Phänotyp koppelnde Verbindung
|
AU7564296A
(en)
|
1995-11-17 |
1997-06-11 |
Ciba-Geigy Ag |
Solid phase synthesis of heterocyclic compounds and combinatorial compound library
|
US5763175A
(en)
|
1995-11-17 |
1998-06-09 |
Lynx Therapeutics, Inc. |
Simultaneous sequencing of tagged polynucleotides
|
US5763263A
(en)
|
1995-11-27 |
1998-06-09 |
Dehlinger; Peter J. |
Method and apparatus for producing position addressable combinatorial libraries
|
US6537776B1
(en)
|
1999-06-14 |
2003-03-25 |
Diversa Corporation |
Synthetic ligation reassembly in directed evolution
|
US6613508B1
(en)
|
1996-01-23 |
2003-09-02 |
Qiagen Genomics, Inc. |
Methods and compositions for analyzing nucleic acid molecules utilizing sizing techniques
|
US5880972A
(en)
|
1996-02-26 |
1999-03-09 |
Pharmacopeia, Inc. |
Method and apparatus for generating and representing combinatorial chemistry libraries
|
AU2537397A
(en)
|
1996-03-22 |
1997-10-10 |
Ontogen Corporation |
Methods for spatially-dispersed positionally-encoded combinatorial library synthesis
|
US6294325B1
(en)
|
1996-07-05 |
2001-09-25 |
The Mount Sinai School Of Medicine Of The City University Of New York |
Cloning and expression of thermostable multi genes and proteins and uses thereof
|
US5821356A
(en)
|
1996-08-12 |
1998-10-13 |
The Perkin Elmer Corporation |
Propargylethoxyamino nucleotides
|
US6355490B1
(en)
|
1996-09-13 |
2002-03-12 |
Jill Edie Hochlowski |
Attached tags for use in combinatorial chemistry synthesis
|
DE19642751A1
(de)
|
1996-10-16 |
1998-04-23 |
Deutsches Krebsforsch |
Saccharid-Bibliothek
|
US5954874A
(en)
|
1996-10-17 |
1999-09-21 |
Hunter; Charles Eric |
Growth of bulk single crystals of aluminum nitride from a melt
|
JP3683282B2
(ja)
|
1996-10-17 |
2005-08-17 |
三菱化学株式会社 |
遺伝子型と表現型の対応付け分子及びその利用
|
PT971946E
(pt)
|
1997-01-21 |
2006-11-30 |
Gen Hospital Corp |
Selecção de proteínas utilizando fusões arn-proteína
|
US6261804B1
(en)
|
1997-01-21 |
2001-07-17 |
The General Hospital Corporation |
Selection of proteins using RNA-protein fusions
|
US6127533A
(en)
|
1997-02-14 |
2000-10-03 |
Isis Pharmaceuticals, Inc. |
2'-O-aminooxy-modified oligonucleotides
|
US5739314A
(en)
|
1997-04-25 |
1998-04-14 |
Hybridon, Inc. |
Method for synthesizing 2'-O-substituted pyrimidine nucleosides
|
JP4060892B2
(ja)
|
1997-05-28 |
2008-03-12 |
ディサーナ リミテッド |
タンパク質のin vitroディスプレイ及び進化のための選択粒子としてのリボソーム複合体
|
US6969584B2
(en)
|
1997-06-12 |
2005-11-29 |
Rigel Pharmaceuticals, Inc. |
Combinatorial enzymatic complexes
|
WO1998058256A1
(en)
|
1997-06-16 |
1998-12-23 |
The University Of North Carolina At Chapel Hill |
PEPTIDO OLIGONUCLEOTIDES (PONs) AND THEIR COMBINATORIAL LIBRARIES
|
US6607878B2
(en)
|
1997-10-06 |
2003-08-19 |
Stratagene |
Collections of uniquely tagged molecules
|
US6348322B1
(en)
|
1997-10-17 |
2002-02-19 |
Duke University |
Method of screening for specific binding interactions
|
US20030004122A1
(en)
|
1997-11-05 |
2003-01-02 |
Leonid Beigelman |
Nucleotide triphosphates and their incorporation into oligonucleotides
|
US6232066B1
(en)
|
1997-12-19 |
2001-05-15 |
Neogen, Inc. |
High throughput assay system
|
JP2002540380A
(ja)
|
1998-02-21 |
2002-11-26 |
ウィッシス・テクノロジー・ファウンデーション・インコーポレイテッド |
一次元の化学化合物アレイ及びそれらのアセイ方法
|
US6316616B1
(en)
|
1998-04-02 |
2001-11-13 |
President And Fellows Of Harvard College |
Parallel combinatorial approach to the discovery and optimization of catalysts and uses thereof
|
IL138668A0
(en)
|
1998-04-03 |
2001-10-31 |
Phylos Inc |
Addressable protein arrays
|
WO1999054458A1
(en)
|
1998-04-17 |
1999-10-28 |
Whitehead Institute For Biomedical Research |
Use of a ribozyme to join nucleic acids and peptides
|
US6780981B1
(en)
|
1998-05-15 |
2004-08-24 |
Oxford Gene Technology Ip Limited |
Libraries of oligomers labeled with different tags
|
US6287765B1
(en)
|
1998-05-20 |
2001-09-11 |
Molecular Machines, Inc. |
Methods for detecting and identifying single molecules
|
EP1079859B1
(de)
*
|
1998-05-22 |
2010-07-14 |
The Board Of Trustees Of The Leland Stanford Junior University |
Bifunktionelle moleküle sowie darauf basierende therapien.
|
US6096875A
(en)
|
1998-05-29 |
2000-08-01 |
The Perlein-Elmer Corporation |
Nucleotide compounds including a rigid linker
|
US5948648A
(en)
|
1998-05-29 |
1999-09-07 |
Khan; Shaheer H. |
Nucleotide compounds including a rigid linker
|
CN1314913A
(zh)
|
1998-06-10 |
2001-09-26 |
格里科设计公司 |
有针对性的组合化合物库及其进行筛选所用的高效测定方法
|
AU6502599A
(en)
|
1998-10-05 |
2000-04-26 |
Lynx Therapeutics, Inc. |
Enzymatic synthesis of oligonucleotide tags
|
EP1119530A2
(de)
|
1998-10-09 |
2001-08-01 |
Pharmacopeia, Inc. |
Auswahl von codes für die codierung von kombinatorischen bibliotheken
|
US6175001B1
(en)
|
1998-10-16 |
2001-01-16 |
The Scripps Research Institute |
Functionalized pyrimidine nucleosides and nucleotides and DNA's incorporating same
|
AU1318400A
(en)
|
1998-10-19 |
2000-05-08 |
Board Of Trustees Of The Leland Stanford Junior University |
Dna-templated combinatorial library chemistry
|
DE69930141T2
(de)
*
|
1998-10-20 |
2006-11-23 |
The Procter & Gamble Company, Cincinnati |
Waschmittel enthaltend modifizierte alkylbenzolsulfonate
|
JP2002528075A
(ja)
|
1998-10-28 |
2002-09-03 |
ノボザイムス アクティーゼルスカブ |
遺伝子ライブラリーの生成方法
|
US5942609A
(en)
|
1998-11-12 |
1999-08-24 |
The Porkin-Elmer Corporation |
Ligation assembly and detection of polynucleotides on solid-support
|
ES2280131T3
(es)
|
1998-12-02 |
2007-09-01 |
Adnexus Therapeutics, Inc. |
Fusiones de adn-proteina y utilizaciones de las mismas.
|
US6087112A
(en)
|
1998-12-30 |
2000-07-11 |
Oligos Etc. Inc. |
Arrays with modified oligonucleotide and polynucleotide compositions
|
AU2225000A
(en)
|
1999-01-08 |
2000-07-24 |
Ceres, Inc. |
Sequence-determined dna fragments and corresponding polypeptides encoded thereby
|
EP1208219A1
(de)
|
1999-04-08 |
2002-05-29 |
Pavel Sergeev |
Synthese von biologisch-aktiven zusammensetzungen in zellen
|
EP2360270B1
(de)
|
1999-05-20 |
2016-11-09 |
Illumina, Inc. |
Kombinatorische Entschlüsselung von Zufallsnukleinsäurearrays
|
JP2003503699A
(ja)
|
1999-06-25 |
2003-01-28 |
ナノスフェアー インコーポレイテッド |
オリゴヌクレオチドが付着しているナノ粒子およびその利用法
|
ATE360706T1
(de)
|
1999-07-27 |
2007-05-15 |
Adnexus Therapeutics Inc |
Peptidakzeptor ligationsverfahren
|
DE60002821T2
(de)
|
1999-08-27 |
2004-05-06 |
Japan Science And Technology Corp., Kawaguchi |
Reversibel photokuppelnde nukleinsäure und phosphoramidit
|
GB9920194D0
(en)
|
1999-08-27 |
1999-10-27 |
Advanced Biotech Ltd |
A heat-stable thermostable DNA polymerase for use in nucleic acid amplification
|
US20020048760A1
(en)
|
1999-12-10 |
2002-04-25 |
Hyseq, Inc. |
Use of mismatch cleavage to detect complementary probes
|
JP2003520050A
(ja)
*
|
2000-01-24 |
2003-07-02 |
フィロス インク. |
タンパク質分析のための高感度多重化診断アッセイ法
|
CA2396755A1
(en)
|
2000-02-03 |
2001-08-09 |
Nanoscale Combinatorial Synthesis, Inc. |
Structure identification methods using mass measurements
|
US7306904B2
(en)
*
|
2000-02-18 |
2007-12-11 |
Olink Ab |
Methods and kits for proximity probing
|
US20020127598A1
(en)
|
2000-03-27 |
2002-09-12 |
Wenqiang Zhou |
Solution-phase combinatorial library synthesis and pharmaceutically active compounds produced thereby
|
US7682837B2
(en)
|
2000-05-05 |
2010-03-23 |
Board Of Trustees Of Leland Stanford Junior University |
Devices and methods to form a randomly ordered array of magnetic beads and uses thereof
|
JP2003533995A
(ja)
|
2000-05-19 |
2003-11-18 |
リチャード、 ビー. ウィリアムズ、 |
核酸およびコードされたポリペプチドのinvitroでの展開
|
US7244560B2
(en)
|
2000-05-21 |
2007-07-17 |
Invitrogen Corporation |
Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
|
DE60127958D1
(de)
|
2000-06-05 |
2007-05-31 |
Novartis Vaccines & Diagnostic |
Mikroarrays für durchführen von proteomanalyse
|
US20020115068A1
(en)
|
2000-06-23 |
2002-08-22 |
Ian Tomlinson |
Matrix screening method
|
EP1299722A1
(de)
|
2000-07-03 |
2003-04-09 |
Merck & Co., Inc. |
Verfahren zum enkodieren kombinatorischer bibliotheken
|
AU2001283056A1
(en)
|
2000-07-27 |
2002-02-13 |
California Institute Of Technology |
A rapid, quantitative method for the mass spectrometric analysis of nucleic acids for gene expression and genotyping
|
US20020072887A1
(en)
|
2000-08-18 |
2002-06-13 |
Sandor Szalma |
Interaction fingerprint annotations from protein structure models
|
AU2002232391A1
(en)
|
2000-10-25 |
2002-05-06 |
City Of Hope |
Candidate region mismatch scanning for genotyping and mutation detection
|
JP2002315577A
(ja)
|
2000-11-14 |
2002-10-29 |
Gencom Co |
核酸ライブラリーの作製方法
|
JP4128453B2
(ja)
|
2001-03-19 |
2008-07-30 |
プレジデント アンド フェロウズ オブ ハーバード カレッジ |
新規分子機能の進化
|
AU2002257076A1
(en)
|
2001-03-19 |
2002-10-03 |
President And Fellows Of Harvard College |
Nucleic acid shuffling
|
WO2002083951A1
(en)
*
|
2001-04-10 |
2002-10-24 |
Northeastern University |
Multiplexed ligand/protein binding assays with pna labels
|
US20040137458A1
(en)
|
2001-05-03 |
2004-07-15 |
Christian Archambault |
Molecular tag code for monitoring a product and process using same
|
WO2004059289A2
(en)
|
2001-05-22 |
2004-07-15 |
Epicentre Technologies |
Target-dependent transcription using deletion mutants of n4 rna polymerase
|
AU2002312389A1
(en)
|
2001-06-05 |
2002-12-16 |
Irm Llc |
Functional proteomic profiling
|
WO2002102820A1
(en)
|
2001-06-20 |
2002-12-27 |
Nuevolution A/S |
Nucleoside derivatives for library preparation
|
DE60221986D1
(de)
*
|
2001-06-20 |
2007-10-04 |
Nuevolution As |
Eine methode zur synthese von matrizenabhängigen molekülen
|
US20060234231A1
(en)
|
2001-06-20 |
2006-10-19 |
Nuevolution A/S |
Microarrays displaying encoded molecules
|
US20040161741A1
(en)
*
|
2001-06-30 |
2004-08-19 |
Elazar Rabani |
Novel compositions and processes for analyte detection, quantification and amplification
|
US20040241688A1
(en)
*
|
2001-07-19 |
2004-12-02 |
Cuneyt Bukusoglu |
Human tissue specific drug screening procedure
|
DE10145226A1
(de)
|
2001-09-13 |
2003-04-10 |
Lifebits Ag |
Herstellung von trägergebundenen Molekülen
|
WO2003038558A2
(en)
|
2001-10-30 |
2003-05-08 |
Nanomics Biosystems Pty, Ltd. |
Device and methods for directed synthesis of chemical libraries
|
WO2003062417A1
(fr)
|
2002-01-22 |
2003-07-31 |
Mitsubishi Chemical Corporation |
Produit de ligation arn-adn, et utilisation correspondante
|
WO2003076943A1
(en)
|
2002-03-08 |
2003-09-18 |
Eidgenössische Technische Hochschule Zürich |
Encoded self-assembling chemical libraries (esachel)
|
IL163822A0
(en)
|
2002-03-15 |
2005-12-18 |
Nuevolution As |
An improved method for synthesising templated molecules
|
AU2003214033A1
(en)
|
2002-03-15 |
2003-09-29 |
Nuevolution A/S |
A building block capable of transferring a functional entity
|
AU2003214032A1
(en)
|
2002-03-15 |
2003-09-29 |
Nuevolution A/S |
A building block forming a c=c double bond upon reaction
|
EP1490384A2
(de)
|
2002-03-15 |
2004-12-29 |
Nuevolution A/S |
Ein baublock zur c-c bindungsbildung
|
EP1487850A2
(de)
|
2002-03-15 |
2004-12-22 |
Nuevolution A/S |
Ein baublock zur c-c bindungsbildung oder c-heteroatom bindungsbildung
|
WO2003082901A2
(en)
|
2002-03-22 |
2003-10-09 |
Emory University |
Template-driven processes for synthesizing polymers and components related to such processes
|
GB0213816D0
(en)
|
2002-06-14 |
2002-07-24 |
Univ Aston |
Method of producing DNA and protein libraries
|
AU2003240436A1
(en)
|
2002-06-20 |
2004-01-06 |
Nuevolution A/S |
Microarrays displaying encoded molecules
|
DE60324964D1
(de)
|
2002-07-15 |
2009-01-08 |
Univ Princeton |
Iap-bindende verbindungen
|
EP1527173A1
(de)
|
2002-07-23 |
2005-05-04 |
Nuevolution A/S |
Gendurchmischung durch wechselnder schablone
|
EP1539980B1
(de)
|
2002-08-01 |
2016-02-17 |
Nuevolution A/S |
MEHRSTUFENSYNTHESE VON MIT MATRIZEN ASSOZIIERTE MOLEKüLEN
|
JP4657919B2
(ja)
|
2002-08-19 |
2011-03-23 |
プレジデント アンド フェローズ オブ ハーバード カレッジ |
進化する新しい分子機能
|
US20040197845A1
(en)
|
2002-08-30 |
2004-10-07 |
Arjang Hassibi |
Methods and apparatus for pathogen detection, identification and/or quantification
|
EP1539953A2
(de)
|
2002-09-12 |
2005-06-15 |
Nuevolution A/S |
Durch nähe unterstützte synthese von mit matrizen versehenen molekülen
|
JP2006500959A
(ja)
|
2002-09-30 |
2006-01-12 |
パラレル バイオサイエンス, インコーポレイテッド |
動的サンプリング結合によるポリヌクレオチド合成および標識化
|
DK1558744T3
(da)
|
2002-10-30 |
2011-10-10 |
Nuevolution As |
Enzymatisk kodning
|
EP1576126A3
(de)
|
2002-10-30 |
2005-10-26 |
Pointilliste, Inc. |
Systeme zum einfangen und zur analyse biologischer partikel und verfahren unter verwendung dieser systeme
|
WO2004050899A2
(en)
|
2002-12-03 |
2004-06-17 |
Archemix Corporation |
Method for in vitro selection of 2’-substituted nucleic acids
|
EP1756277B1
(de)
|
2002-12-19 |
2009-12-02 |
Nuevolution A/S |
Durch quasizufallsstrukturen und funktionen geführte synthesemethode
|
WO2004070005A2
(en)
|
2003-01-29 |
2004-08-19 |
454 Corporation |
Double ended sequencing
|
EP1597394A2
(de)
|
2003-02-21 |
2005-11-23 |
Nuevolution A/S |
Eine methode zur erlangung struktureller information über ein kodiertes molekül
|
EP1597395A2
(de)
|
2003-02-21 |
2005-11-23 |
Nuevolution A/S |
Methode zur herstellung einer bibliothek der zweiten generation
|
JP4054871B2
(ja)
|
2003-02-24 |
2008-03-05 |
独立行政法人産業技術総合研究所 |
耐熱性dnaリガーゼ
|
ATE424455T1
(de)
|
2003-03-20 |
2009-03-15 |
Nuevolution As |
Ligationsvermittelnde codierung von kleinen molekülen
|
WO2004099441A2
(en)
|
2003-05-09 |
2004-11-18 |
Hyscite Discovery As |
Selection and evolution of chemical libraries
|
WO2004110964A2
(en)
|
2003-06-16 |
2004-12-23 |
Nuevolution A/S |
Encoded molecules by translation (emt)
|
WO2005003778A2
(en)
|
2003-07-02 |
2005-01-13 |
Nuevolution A/S |
A method for identifying a synthetic molecule having affinity towards a target
|
EP1652123A2
(de)
|
2003-07-03 |
2006-05-03 |
Biogen Idec MA Inc. |
Fingerabdruck zur strukturellen interaktion (sift)
|
EP1533385A1
(de)
|
2003-09-05 |
2005-05-25 |
Nuevolution A/S |
Matrizenabhängigen Verbindungen zur Herstellung von kodierten Molekülen und gesteuerten Verfahren unter Verwendung dieser Verbindungen
|
US11118215B2
(en)
|
2003-09-18 |
2021-09-14 |
Nuevolution A/S |
Method for obtaining structural information concerning an encoded molecule and method for selecting compounds
|
CN101864412A
(zh)
|
2003-12-17 |
2010-10-20 |
普雷西斯药品公司 |
合成编码文库的方法
|
US7972994B2
(en)
|
2003-12-17 |
2011-07-05 |
Glaxosmithkline Llc |
Methods for synthesis of encoded libraries
|
EP1723255B1
(de)
|
2004-02-17 |
2010-12-29 |
Nuevolution A/S |
Anreicherungsverfahren mit eliminierung durch fehlpaarungshybridisierung
|
WO2005090566A2
(en)
|
2004-03-22 |
2005-09-29 |
Nuevolution A/S |
Ligational encoding using building block oligonucleotides
|
WO2005116213A2
(en)
|
2004-04-15 |
2005-12-08 |
President And Fellows Of Harvard College |
Directed evolution of proteins
|
DK1809743T3
(da)
|
2004-11-08 |
2009-05-04 |
Vipergen Aps |
Strukturel nukleinsyre-styret kemisk syntese
|
DE602005012319D1
(de)
|
2004-11-22 |
2009-02-26 |
Peter Birk Rasmussen |
Matrizengerichtete split-and-mix-synthese von bibliotheken kleiner moleküle
|
DK1836201T4
(da)
|
2004-12-20 |
2013-11-11 |
Genentech Inc |
Pyrrolidininhibitorer af IAP.
|
WO2006079061A2
(en)
|
2005-01-21 |
2006-07-27 |
President And Fellows Of Harvard College |
Free reactant use in nucleic acid-templated synthesis
|
US7968289B2
(en)
|
2005-05-03 |
2011-06-28 |
Ensemble Therapeutics Corporation |
Turn over probes and use thereof for nucleic acid detection
|
BRPI0611474A2
(pt)
|
2005-05-26 |
2010-09-14 |
Ensemble Discovery Corp |
biodetecção por quìmica modelada com ácido nucléico
|
EP1891242A2
(de)
|
2005-05-31 |
2008-02-27 |
Ensemble Discovery Corporation |
Ankerunterstützte fragmentauswahl und gerichtete montage
|
WO2006135654A2
(en)
|
2005-06-07 |
2006-12-21 |
President And Fellows Of Harvard College |
Polymer evolution via templated synthesis related applications
|
US20090149347A1
(en)
|
2005-06-07 |
2009-06-11 |
President And Fellows Of Harvard College |
Ordered Multi-Step Synthesis by Nucleic Acid-Mediated Chemistry
|
AU2006257915B2
(en)
|
2005-06-09 |
2011-09-08 |
Glaxosmithkline Llc |
Methods for synthesis of encoded libraries
|
US8183178B2
(en)
|
2005-06-17 |
2012-05-22 |
President And Fellows Of Harvard College |
Iterated branching reaction pathways via nucleic acid-mediated chemistry
|
WO2006138560A2
(en)
|
2005-06-17 |
2006-12-28 |
President And Fellows Of Harvard College |
Nucleic acid-templated chemistry in organic solvents
|
WO2007011722A2
(en)
|
2005-07-15 |
2007-01-25 |
President And Fellows Of Harvard College |
Reaction discovery system
|
WO2007016488A2
(en)
|
2005-07-29 |
2007-02-08 |
Ensemble Discovery Corporation |
Analysis of encoded chemical libraries
|
CA2626325A1
(en)
|
2005-10-28 |
2007-05-10 |
Praecis Pharmaceuticals Incorporated |
Methods for identifying compounds of interest using encoded libraries
|
US9574189B2
(en)
|
2005-12-01 |
2017-02-21 |
Nuevolution A/S |
Enzymatic encoding methods for efficient synthesis of large libraries
|
WO2007124758A1
(en)
|
2006-05-03 |
2007-11-08 |
Vipergen Aps |
A method for preparing compounds by nucleic acid directed synthesis
|
US20100143499A1
(en)
|
2006-07-24 |
2010-06-10 |
Tetralogic Pharmaceuticals Corporation |
Dimeric iap inhibitors
|
AU2007297671A1
(en)
|
2006-09-18 |
2008-03-27 |
Ensemble Discovery Corporation |
Receptor family profiling
|
CA2664649A1
(en)
|
2006-09-28 |
2008-05-08 |
Ensemble Discovery Corporation |
Compositions and methods for biodetection by nucleic acid-templated chemistry
|
WO2008094599A2
(en)
|
2007-01-30 |
2008-08-07 |
Rockefeller University, The |
Modified rna ligase for efficient 3' modification of rna
|
WO2009018003A2
(en)
|
2007-07-27 |
2009-02-05 |
Ensemble Discovery Corporation |
Detection assays and use thereof
|
WO2009077173A2
(en)
|
2007-12-19 |
2009-06-25 |
Philochem Ag |
Dna-encoded chemical libraries
|
TW201011006A
(en)
|
2008-06-16 |
2010-03-16 |
Nuevolution As |
IAP binding compounds
|
DK2558577T3
(en)
|
2010-04-16 |
2019-04-01 |
Nuevolution As |
Bi-functional complexes and methods for the preparation and use of such complexes
|
CA3107001A1
(en)
|
2018-07-23 |
2020-01-30 |
Abexxa Biologics, Inc. |
Antibodies targeting a complex comprising non-classical hla-i and neoantigen and their methods of use
|