DK319685A - Monoklonale antistoffer, fremgangsmaade til frembringelse af antistofferne, hybridomaceller, der producerer antistofferne, og anvendelse af antistofferne - Google Patents

Monoklonale antistoffer, fremgangsmaade til frembringelse af antistofferne, hybridomaceller, der producerer antistofferne, og anvendelse af antistofferne Download PDF

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Publication number
DK319685A
DK319685A DK319685A DK319685A DK319685A DK 319685 A DK319685 A DK 319685A DK 319685 A DK319685 A DK 319685A DK 319685 A DK319685 A DK 319685A DK 319685 A DK319685 A DK 319685A
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DK
Denmark
Prior art keywords
antibodies
producing
procedures
hybridoma cells
monoclonal
Prior art date
Application number
DK319685A
Other languages
English (en)
Other versions
DK319685D0 (da
Inventor
Lars Saeegaard Nielsen
Peter Andre Andreasen
Keld Danae
Original Assignee
Fonden Til Fremme Af Eksperime
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8120155&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK319685(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fonden Til Fremme Af Eksperime filed Critical Fonden Til Fremme Af Eksperime
Priority to DK319685A priority Critical patent/DK319685A/da
Publication of DK319685D0 publication Critical patent/DK319685D0/da
Priority to EP19930202290 priority patent/EP0585995A1/en
Priority to AT86904118T priority patent/ATE103818T1/de
Priority to DE3689766T priority patent/DE3689766T2/de
Priority to EP86904118A priority patent/EP0229126B1/en
Priority to AU61446/86A priority patent/AU6144686A/en
Priority to JP50415186A priority patent/JPS63500564A/ja
Priority to PCT/DK1986/000080 priority patent/WO1987000549A1/en
Publication of DK319685A publication Critical patent/DK319685A/da
Priority to US07/900,364 priority patent/US5422245A/en
Priority to US08/466,965 priority patent/US6271352B1/en
Priority to US09/922,718 priority patent/US20020012950A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • C07K14/8132—Plasminogen activator inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/81—Protease inhibitors
    • G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • G01N2333/811—Serine protease (E.C. 3.4.21) inhibitors
    • G01N2333/8121—Serpins
    • G01N2333/8132—Plasminogen activator inhibitors
DK319685A 1985-07-12 1985-07-12 Monoklonale antistoffer, fremgangsmaade til frembringelse af antistofferne, hybridomaceller, der producerer antistofferne, og anvendelse af antistofferne DK319685A (da)

Priority Applications (11)

Application Number Priority Date Filing Date Title
DK319685A DK319685A (da) 1985-07-12 1985-07-12 Monoklonale antistoffer, fremgangsmaade til frembringelse af antistofferne, hybridomaceller, der producerer antistofferne, og anvendelse af antistofferne
PCT/DK1986/000080 WO1987000549A1 (en) 1985-07-12 1986-07-11 Plasminogen activator inhibitor monoclonal antibodies, hybridomas, monoclonal antibody production and use of the antibodies for purification, removal, inhibition or assay of the inhibitors
JP50415186A JPS63500564A (ja) 1985-07-12 1986-07-11 モノクロ−ナル抗体
DE3689766T DE3689766T2 (de) 1985-07-12 1986-07-11 Monoklonaler antikörper-inhibitor des plasminogenaktivators, hybridomen, herstellung monoklonaler antikörper und deren verwendung zur reinigung, beseitigung, inhibition oder zum testverfahren von inhibitoren.
AT86904118T ATE103818T1 (de) 1985-07-12 1986-07-11 Monoklonaler antikoerper-inhibitor des plasminogenaktivators, hybridomen, herstellung monoklonaler antikoerper und deren verwendung zur reinigung, beseitigung, inhibition oder zum testverfahren von inhibitoren.
EP19930202290 EP0585995A1 (en) 1985-07-12 1986-07-11 Pure human endothelial type plasminogen activator inhibitor (e-PAI) and production thereof
EP86904118A EP0229126B1 (en) 1985-07-12 1986-07-11 Plasminogen activator inhibitor monoclonal antibodies, hybridomas, monoclonal antibody production and use of the antibodies for purification, removal, inhibition or assay of the inhibitors
AU61446/86A AU6144686A (en) 1985-07-12 1986-07-11 Plasminogen activator inhibitor monoclonal antibodies, hybridomas, monoclonal antibody production and use of the antibodies for purification, removal, inhibition or assay of the inhibitors
US07/900,364 US5422245A (en) 1985-07-12 1992-06-18 Plasminogen activator inhibitor monoclonal antibodies, hybridomas, monoclonal antibody production and use of the antibodies for assay of the inhibitors
US08/466,965 US6271352B1 (en) 1985-07-12 1995-06-06 PAI-1 determination and use thereof
US09/922,718 US20020012950A1 (en) 1985-07-12 2001-08-07 Pai-1 determination and use thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK319685A DK319685A (da) 1985-07-12 1985-07-12 Monoklonale antistoffer, fremgangsmaade til frembringelse af antistofferne, hybridomaceller, der producerer antistofferne, og anvendelse af antistofferne

Publications (2)

Publication Number Publication Date
DK319685D0 DK319685D0 (da) 1985-07-12
DK319685A true DK319685A (da) 1987-01-13

Family

ID=8120155

Family Applications (1)

Application Number Title Priority Date Filing Date
DK319685A DK319685A (da) 1985-07-12 1985-07-12 Monoklonale antistoffer, fremgangsmaade til frembringelse af antistofferne, hybridomaceller, der producerer antistofferne, og anvendelse af antistofferne

Country Status (6)

Country Link
EP (1) EP0229126B1 (da)
JP (1) JPS63500564A (da)
AU (1) AU6144686A (da)
DE (1) DE3689766T2 (da)
DK (1) DK319685A (da)
WO (1) WO1987000549A1 (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4952512A (en) * 1984-06-22 1990-08-28 Loskutoff David J Gene encoding an inhibitor of tissue-type and urokinase-type plasminogen activators
US5102787A (en) * 1987-07-10 1992-04-07 Miho Sasamata Method, device and kit for measurement of tissue plasminogen activator activity
DE3742997A1 (de) * 1987-12-18 1989-06-29 Behringwerke Ag Peptide, verfahren zu ihrer herstellung, ihre verwendung zur gewinnung von antikoerpern sowie deren verwendung zur blockierung der pai-1-aktivitaet menschlichen blutes
JP2750732B2 (ja) * 1988-04-04 1998-05-13 帝人株式会社 ヒトプラスミノーゲンアクティベーターインヒビター・１−ヒト組織プラスミノーゲンアクティベーター複合体の免疫学的測定方法
DE68911574T2 (de) * 1988-04-04 1994-05-11 Teijin Ltd Reagenzsystem zur Bestimmung des Komplexes des menschlichen Plasminogenaktivator-Inhibitors und des menschlichen Gewebeplasminogenaktivators und Testsatz dafür.
JP2868530B2 (ja) * 1989-04-03 1999-03-10 帝人株式会社 プラスミノーゲンアクティベーターインヒビターに対するモノクローナル抗体
DE69033653T2 (de) * 1989-04-07 2001-06-07 Cancerforskningsfonden Af 1989 Plasminogen-aktivator-rezeptor vom urokinasetyp
CA2042594A1 (en) * 1989-10-02 1991-04-03 Shuichiro Hino Kit and method for the immunological assay of a human tissue plasminogen activator-human plasminogen activator complex
DK85193D0 (da) * 1993-07-16 1993-07-16 Cancerforskningsfondet Af 1989 Suppression of inhibitors
ES2770507T3 (es) * 2013-08-13 2020-07-01 Sanofi Sa Anticuerpos dirigidos contra el inhibidor de los activadores del plasminógeno de tipo 1 (PAI-1) y usos de los mismos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE896543A (fr) * 1983-04-22 1983-08-16 Wallone Region Ensembles d'anticorps monoclonaux deriges contre les proteines humaines impliquees dans la coagulation et la fibrinolyse du sang
US4791068A (en) * 1984-06-22 1988-12-13 Scripps Clinic And Research Foundation Diagnostic assay for inhibitor of tissue-type and urokinase-type plasminogen activators
DE3586577T2 (de) * 1984-07-26 1993-03-25 Teijin Ltd Immunologische bestimmung von menschlichem plasmin/alpha-2-plasmin-hemmstoff.
JP5249920B2 (ja) * 2007-07-05 2013-07-31 パナソニック株式会社 データ処理装置、データ処理方法、データ処理プログラム、記録媒体及び集積回路

Also Published As

Publication number Publication date
JPS63500564A (ja) 1988-03-03
DE3689766D1 (de) 1994-05-11
EP0229126A1 (en) 1987-07-22
WO1987000549A1 (en) 1987-01-29
EP0229126B1 (en) 1994-04-06
DE3689766T2 (de) 1994-12-01
DK319685D0 (da) 1985-07-12
AU6144686A (en) 1987-02-10

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