DK3087183T3 - Modulation af angiopoietin-3-lignende ekspression - Google Patents

Modulation af angiopoietin-3-lignende ekspression Download PDF

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Publication number
DK3087183T3
DK3087183T3 DK14874081.4T DK14874081T DK3087183T3 DK 3087183 T3 DK3087183 T3 DK 3087183T3 DK 14874081 T DK14874081 T DK 14874081T DK 3087183 T3 DK3087183 T3 DK 3087183T3
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angiopoietin
modulation
expression
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DK14874081.4T
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English (en)
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Susan M Freier
Mark J Graham
Rosanne M Crooke
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Ionis Pharmaceuticals Inc
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    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/7115—Nucleic acids or oligonucleotides having modified bases, i.e. other than adenine, guanine, cytosine, uracil or thymine
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    • A61K31/7105—Natural ribonucleic acids, i.e. containing only riboses attached to adenine, guanine, cytosine or uracil and having 3'-5' phosphodiester links
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    • A61K31/712—Nucleic acids or oligonucleotides having modified sugars, i.e. other than ribose or 2'-deoxyribose
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DK14874081.4T 2013-12-24 2014-12-24 Modulation af angiopoietin-3-lignende ekspression DK3087183T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361920652P 2013-12-24 2013-12-24
PCT/US2014/072303 WO2015100394A1 (en) 2013-12-24 2014-12-24 Modulation of angiopoietin-like 3 expression

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DK3087183T3 true DK3087183T3 (da) 2020-09-14

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US (3) US20170037409A1 (da)
EP (2) EP3087183B1 (da)
JP (2) JP6643996B2 (da)
KR (2) KR102198082B1 (da)
CN (3) CN105814204B (da)
AU (2) AU2014369900B2 (da)
BR (1) BR112016013473A2 (da)
CA (1) CA2931510A1 (da)
DK (1) DK3087183T3 (da)
ES (1) ES2830257T3 (da)
HU (1) HUE052243T2 (da)
IL (2) IL245707B (da)
MX (1) MX2016008462A (da)
NZ (1) NZ720286A (da)
PL (1) PL3087183T3 (da)
PT (1) PT3087183T (da)
RU (1) RU2706964C2 (da)
SI (1) SI3087183T1 (da)
WO (1) WO2015100394A1 (da)

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WO2020038377A1 (zh) 2018-08-21 2020-02-27 苏州瑞博生物技术有限公司 一种核酸、含有该核酸的药物组合物和缀合物及其用途
JP7376952B2 (ja) 2018-09-30 2023-11-09 スーチョウ リボ ライフ サイエンス カンパニー、リミテッド ｓｉＲＮＡ複合体及びその調製方法と使用
WO2020099525A2 (en) * 2018-11-13 2020-05-22 Lipigon Pharmaceuticals Ab Oligonucleotides influencing the regulation of the fatty acid metabolism
WO2020099482A2 (en) * 2018-11-13 2020-05-22 Lipigon Pharmaceuticals Ab Angptl 3 oligonucleotides influencing the regulation of the fatty acid metabolism
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WO2022079222A1 (en) * 2020-10-16 2022-04-21 Sanofi Novel rna compositions and methods for inhibiting angptl3
CN113956345B (zh) * 2021-09-10 2024-04-23 北京大学 Angpt4蛋白及其编码基因在调控心脏损伤后的修复与再生能力中的应用
US20230193271A1 (en) 2021-12-22 2023-06-22 Regeneron Pharmaceuticals, Inc. Treatment Of Kidney Diseases With Angiopoietin Like 3 (ANGPTL3) Inhibitors
WO2023134705A1 (zh) * 2022-01-11 2023-07-20 上海金中锘美生物医药科技有限公司 抑制angptl3表达的rna干扰剂及其用途
WO2024044542A2 (en) * 2022-08-22 2024-02-29 Arrowhead Pharmaceuticals, Inc. Methods for the treatment of angptl3-related diseases and disorders
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PT3087183T (pt) 2020-10-08
EP3087183A4 (en) 2017-08-16
EP3087183B1 (en) 2020-08-26
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