DK2947996T3 - Fremgangsmåde til fremstilling af beta-casein-sammensætninger - Google Patents
Fremgangsmåde til fremstilling af beta-casein-sammensætninger Download PDFInfo
- Publication number
- DK2947996T3 DK2947996T3 DK14701187.8T DK14701187T DK2947996T3 DK 2947996 T3 DK2947996 T3 DK 2947996T3 DK 14701187 T DK14701187 T DK 14701187T DK 2947996 T3 DK2947996 T3 DK 2947996T3
- Authority
- DK
- Denmark
- Prior art keywords
- casein
- composition
- beta
- milk
- temperature
- Prior art date
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- 102000011632 Caseins Human genes 0.000 title claims description 216
- 108010076119 Caseins Proteins 0.000 title claims description 216
- 235000021247 β-casein Nutrition 0.000 title claims description 156
- 239000000203 mixture Substances 0.000 title claims description 148
- 238000000034 method Methods 0.000 title claims description 105
- 238000001471 micro-filtration Methods 0.000 claims description 177
- 238000011026 diafiltration Methods 0.000 claims description 100
- 239000012465 retentate Substances 0.000 claims description 96
- 235000013336 milk Nutrition 0.000 claims description 92
- 239000008267 milk Substances 0.000 claims description 92
- 210000004080 milk Anatomy 0.000 claims description 92
- 239000012466 permeate Substances 0.000 claims description 85
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims description 59
- 235000021240 caseins Nutrition 0.000 claims description 59
- 235000018102 proteins Nutrition 0.000 claims description 59
- 102000004169 proteins and genes Human genes 0.000 claims description 59
- 108090000623 proteins and genes Proteins 0.000 claims description 59
- 239000005018 casein Substances 0.000 claims description 57
- 238000000108 ultra-filtration Methods 0.000 claims description 44
- 230000008569 process Effects 0.000 claims description 33
- 239000003085 diluting agent Substances 0.000 claims description 24
- 102000004506 Blood Proteins Human genes 0.000 claims description 20
- 108010017384 Blood Proteins Proteins 0.000 claims description 20
- GNFTZDOKVXKIBK-UHFFFAOYSA-N 3-(2-methoxyethoxy)benzohydrazide Chemical compound COCCOC1=CC=CC(C(=O)NN)=C1 GNFTZDOKVXKIBK-UHFFFAOYSA-N 0.000 claims description 14
- 239000012141 concentrate Substances 0.000 claims description 9
- 238000012545 processing Methods 0.000 claims description 9
- 238000001694 spray drying Methods 0.000 claims description 9
- 238000001223 reverse osmosis Methods 0.000 claims description 8
- 239000011148 porous material Substances 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 5
- 238000000746 purification Methods 0.000 claims description 5
- 239000007787 solid Substances 0.000 claims description 5
- 239000005862 Whey Substances 0.000 claims description 3
- 102000007544 Whey Proteins Human genes 0.000 claims description 3
- 108010046377 Whey Proteins Proteins 0.000 claims description 3
- 238000001704 evaporation Methods 0.000 claims description 3
- 230000008020 evaporation Effects 0.000 claims description 3
- 238000004108 freeze drying Methods 0.000 claims description 3
- 238000001728 nano-filtration Methods 0.000 claims description 3
- 239000000693 micelle Substances 0.000 description 37
- 238000010438 heat treatment Methods 0.000 description 27
- 239000012528 membrane Substances 0.000 description 21
- 239000000047 product Substances 0.000 description 18
- 239000000843 powder Substances 0.000 description 16
- 239000000243 solution Substances 0.000 description 15
- 238000001914 filtration Methods 0.000 description 14
- FGUUSXIOTUKUDN-IBGZPJMESA-N C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 Chemical compound C1(=CC=CC=C1)N1C2=C(NC([C@H](C1)NC=1OC(=NN=1)C1=CC=CC=C1)=O)C=CC=C2 FGUUSXIOTUKUDN-IBGZPJMESA-N 0.000 description 13
- 235000020183 skimmed milk Nutrition 0.000 description 13
- 230000004907 flux Effects 0.000 description 8
- 239000007788 liquid Substances 0.000 description 8
- 241000283690 Bos taurus Species 0.000 description 7
- 238000004458 analytical method Methods 0.000 description 7
- 238000001962 electrophoresis Methods 0.000 description 7
- 238000009928 pasteurization Methods 0.000 description 7
- 125000006850 spacer group Chemical group 0.000 description 7
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 description 6
- 229910001424 calcium ion Inorganic materials 0.000 description 6
- 229940012957 plasmin Drugs 0.000 description 6
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
- 150000001413 amino acids Chemical class 0.000 description 5
- 238000010790 dilution Methods 0.000 description 5
- 239000012895 dilution Substances 0.000 description 5
- 230000002779 inactivation Effects 0.000 description 5
- 241000124008 Mammalia Species 0.000 description 4
- 238000005251 capillar electrophoresis Methods 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- 238000003860 storage Methods 0.000 description 4
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
- 239000011575 calcium Substances 0.000 description 3
- 229910052791 calcium Inorganic materials 0.000 description 3
- 230000029087 digestion Effects 0.000 description 3
- 235000020256 human milk Nutrition 0.000 description 3
- 210000004251 human milk Anatomy 0.000 description 3
- 238000002203 pretreatment Methods 0.000 description 3
- 239000012460 protein solution Substances 0.000 description 3
- 239000008399 tap water Substances 0.000 description 3
- 235000020679 tap water Nutrition 0.000 description 3
- 238000005406 washing Methods 0.000 description 3
- 235000008939 whole milk Nutrition 0.000 description 3
- 108050000244 Alpha-s1 casein Proteins 0.000 description 2
- 102000014171 Milk Proteins Human genes 0.000 description 2
- 108010011756 Milk Proteins Proteins 0.000 description 2
- ONIBWKKTOPOVIA-UHFFFAOYSA-N Proline Natural products OC(=O)C1CCCN1 ONIBWKKTOPOVIA-UHFFFAOYSA-N 0.000 description 2
- 238000007792 addition Methods 0.000 description 2
- 235000014633 carbohydrates Nutrition 0.000 description 2
- 150000001720 carbohydrates Chemical class 0.000 description 2
- 229940021722 caseins Drugs 0.000 description 2
- 238000010924 continuous production Methods 0.000 description 2
- 235000013365 dairy product Nutrition 0.000 description 2
- 238000005115 demineralization Methods 0.000 description 2
- 238000007865 diluting Methods 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 229910052500 inorganic mineral Inorganic materials 0.000 description 2
- 235000020121 low-fat milk Nutrition 0.000 description 2
- 235000021243 milk fat Nutrition 0.000 description 2
- 235000021239 milk protein Nutrition 0.000 description 2
- 239000011707 mineral Substances 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 238000010979 pH adjustment Methods 0.000 description 2
- 230000000717 retained effect Effects 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 102100038920 Alpha-S1-casein Human genes 0.000 description 1
- 102000009366 Alpha-s1 casein Human genes 0.000 description 1
- 108050001786 Alpha-s2 casein Proteins 0.000 description 1
- 235000002198 Annona diversifolia Nutrition 0.000 description 1
- 101000741065 Bos taurus Beta-casein Proteins 0.000 description 1
- 241000282836 Camelus dromedarius Species 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- 241000282994 Cervidae Species 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 241000282842 Lama glama Species 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 238000010923 batch production Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 239000004202 carbamide Substances 0.000 description 1
- 229940071162 caseinate Drugs 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 238000011437 continuous method Methods 0.000 description 1
- 238000006731 degradation reaction Methods 0.000 description 1
- 238000004925 denaturation Methods 0.000 description 1
- 230000036425 denaturation Effects 0.000 description 1
- VHJLVAABSRFDPM-QWWZWVQMSA-N dithiothreitol Chemical compound SC[C@@H](O)[C@H](O)CS VHJLVAABSRFDPM-QWWZWVQMSA-N 0.000 description 1
- 238000005265 energy consumption Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 235000013861 fat-free Nutrition 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 235000013373 food additive Nutrition 0.000 description 1
- 239000002778 food additive Substances 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 230000003993 interaction Effects 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 238000005374 membrane filtration Methods 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 235000020185 raw untreated milk Nutrition 0.000 description 1
- 238000007430 reference method Methods 0.000 description 1
- 238000004007 reversed phase HPLC Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000000935 solvent evaporation Methods 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 235000021246 κ-casein Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
- A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
- A23J1/202—Casein or caseinates
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
- A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C9/00—Milk preparations; Milk powder or milk powder preparations
- A23C9/14—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment
- A23C9/142—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration
- A23C9/1422—Milk preparations; Milk powder or milk powder preparations in which the chemical composition of the milk is modified by non-chemical treatment by dialysis, reverse osmosis or ultrafiltration by ultrafiltration, microfiltration or diafiltration of milk, e.g. for separating protein and lactose; Treatment of the UF permeate
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
- A23J3/00—Working-up of proteins for foodstuffs
- A23J3/04—Animal proteins
- A23J3/08—Dairy proteins
- A23J3/10—Casein
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4732—Casein
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23C—DAIRY PRODUCTS, e.g. MILK, BUTTER OR CHEESE; MILK OR CHEESE SUBSTITUTES; MAKING THEREOF
- A23C2210/00—Physical treatment of dairy products
- A23C2210/20—Treatment using membranes, including sterile filtration
- A23C2210/206—Membrane filtration of a permeate obtained by ultrafiltration, nanofiltration or microfiltration
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2200/00—Function of food ingredients
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- Water Supply & Treatment (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Nutrition Science (AREA)
- Analytical Chemistry (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Dairy Products (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Claims (16)
1. Fremgangsmåde til fremstilling af en beta-kasein-indeholdende sammensætning, hvilken fremgangsmåde omfatter trinnene: a) at forvarme en mælk ved at justere den til en forvarmningstemperatur (Tpre) i området på 20-60 grader C og med en holdetid i området på 1 minut -1 time, hvorved der tilvejebringes en varm mælk, b) at udsætte den varme mælk for mikrofiltrering (MF), hvorved der tilvejebringes et første MF-permeat og et første MF-retentat, c) eventuelt at udsætte det første MF-retentat for MF-diafiltrering, d) at justere temperaturen af en første sammensætning, der er afledt af det første MF-retentat, til en kold temperatur (Tk0|d) i området på 0-15 grader C og holde temperaturen af den første sammensætning inden for dette område i en varighed (tk0id) på mindst 0,5 timer, hvorved der opnås en afkølet første sammensætning, e) at udsætte den afkølede første sammensætning for MF, hvorved der opnås et andet retentat og et andet permeat, hvor det andet permeat er beriget i forhold til beta-kasein, og f) eventuelt at udsætte det andet MF-retentat for MF-diafiltrering, g) eventuelt at udsætte en anden sammensætning, der er afledt af det andet permeat, for et eller flere yderligere behandlingstrin, f.eks. yderligere oprensnings- og/eller koncentrationstrin, hvorved den beta-kasein-indeholdende sammensætning tilvejebringes.
2. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor filteret for MF af den varme mælk har en nominel porestørrelse i området på 0,005-0,3 mikrometer.
3. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor temperaturen af tilførslen under MF af den varme mælk holdes på en temperatur (TwMF) på mindst 20 grader C.
4. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor temperaturen af tilførslen og retentatstrømmen holdes inden for det varme MF-temperaturområde under mindst en del af MF-diafiltreringen.
5. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor mindst en del af MF-diafiltreringen indbefatter anvendelsen af et første fortyndingsmiddel, som har en koncentration på Ca2+ på mindst 0,01 g/kg.
6. Fremgangsmåde ifølge krav 5, hvor det første fortyndingsmiddel har en pH i området på 6-8.
7. Fremgangsmåde ifølge krav 5 eller 6, hvor det første fortyndingsmiddel omfatter et ultrafiltrerings-(UF)-permeat af mælk eller valle.
8. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor den første sammensætning omfatter en samlet mængde af kasein på mindst 90 vægtprocent i forhold til den samlede mængde af protein af den første sammensætning og en samlet mængde af mælkeserumprotein på højst 10 vægtprocent i forhold til den samlede mængde af protein af den første sammensætning.
9. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor den første sammensætning omfatter en samlet mængde af beta-kasein på mindst 20 vægtprocent i forhold til den samlede mængde af kasein.
10. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvilken fremgangsmåde omfatter trin c), og hvor den første sammensætning omfatter diafiltreringsretentat eller et proteinkoncentrat deraf.
11. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor den første sammensætning holdes inden for det kolde temperaturområde i mindst 1 time før trin e).
12. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor den afkølede første sammensætning har en temperatur i området på 3-12 grader C.
13. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor fremgangsmåden omfatter trin g).
14. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor trin g) indbefatter en forøgelse af vægtprocenten af beta-kasein af den anden sammensætning til mindst 50 vægtprocent på tørvægtbasis.
15. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor trin g) indbefatter en forøgelse af faststofandelen af den anden sammensætning til mindst 5 vægtprocent.
16. Fremgangsmåde ifølge et hvilket som helst af de foregående krav, hvor koncentrationen i trin g) indbefatter en eller flere processer udvalgt fra gruppen bestående af ultrafiltrering, nanofiltrering, omvendt osmose, fordampning, spraytørring og frysetørring.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361755732P | 2013-01-23 | 2013-01-23 | |
| EP13152410 | 2013-01-23 | ||
| PCT/EP2014/051315 WO2014114709A2 (en) | 2013-01-23 | 2014-01-23 | Method of producing beta-casein compositions and related products |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK2947996T3 true DK2947996T3 (da) | 2017-03-27 |
| DK2947996T4 DK2947996T4 (da) | 2020-03-02 |
Family
ID=47603429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK14701187.8T DK2947996T4 (da) | 2013-01-23 | 2014-01-23 | Fremgangsmåde til fremstilling af beta-casein-sammensætninger |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US11470857B2 (da) |
| EP (2) | EP3172969A1 (da) |
| JP (1) | JP6426108B2 (da) |
| KR (1) | KR102268784B1 (da) |
| CN (2) | CN104981165A (da) |
| AU (2) | AU2014209964B2 (da) |
| BR (1) | BR112015017384B1 (da) |
| CA (1) | CA2897904C (da) |
| DK (1) | DK2947996T4 (da) |
| ES (1) | ES2620669T5 (da) |
| MX (1) | MX2015009390A (da) |
| PT (1) | PT2947996T (da) |
| RU (2) | RU2668393C2 (da) |
| WO (1) | WO2014114709A2 (da) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2014209964B2 (en) | 2013-01-23 | 2017-04-13 | Arla Foods Amba | Method of producing beta-casein compositions and related products |
| FI126179B (en) * | 2015-02-12 | 2016-07-29 | Valio Oy | Method for producing a milk-based product |
| FI129567B (en) * | 2015-08-31 | 2022-04-29 | Valio Oy | Method of making a milk - based product |
| CN106198692B (zh) * | 2016-08-31 | 2017-12-01 | 内蒙古蒙牛乳业（集团）股份有限公司 | 检测牛乳中A1β‑酪蛋白及A2β‑酪蛋白的方法 |
| KR20230031901A (ko) | 2020-07-06 | 2023-03-07 | 아를라 푸즈 에이엠비에이 | 카제인 가수분해물의 제조방법 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2592769B1 (fr) | 1986-01-10 | 1990-10-12 | Agronomique Inst Nat Rech | Procede d'obtention d'une matiere enrichie en caseine beta, appareillage pour la mise en oeuvre de ce procede, et application des produits obtenus par ce procede comme aliments, complements alimentaires ou additifs en industrie alimentaire et pharmaceutique ou dans la preparation de peptides a activite physiologique |
| FR2663637B1 (fr) | 1990-06-25 | 1992-09-18 | Eurial | Procede et dispositif pour l'obtention de caseine beta. |
| SU1824700A1 (ru) * | 1990-06-28 | 1996-04-27 | Научно-производственное объединение маслодельной и сыродельной промышленности "Углич" | Способ получения концентрата молочного сырья |
| US5169666A (en) | 1991-11-14 | 1992-12-08 | The United States Of America As Represented By The Secretary Of Agriculture | Preparation of simulated human milk protein by low temperature microfiltration |
| WO1994006306A1 (en) | 1992-09-22 | 1994-03-31 | New Zealand Dairy Board | A process for producing beta-casein enriched products |
| CA2151506A1 (en) * | 1992-12-11 | 1994-06-23 | Gustavo Bounous | Process for producing an undenatured whey protein concentrate |
| FR2809595B1 (fr) * | 2000-06-05 | 2003-10-03 | B S A | Derive laitier presentant une composition minerale et en acides amines selectivement modifiee, procedes pour sa fabrication, et utilisation. |
| SE518901C2 (sv) * | 2001-03-08 | 2002-12-03 | Tetra Laval Holdings & Finance | Metod för förbehandling av mjölk vid mikrofiltrering |
| US7500982B2 (en) * | 2005-06-22 | 2009-03-10 | Futurematrix Interventional, Inc. | Balloon dilation catheter having transition from coaxial lumens to non-coaxial multiple lumens |
| TW200740373A (en) | 2005-06-30 | 2007-11-01 | Fonterra Co Operative Group | Dairy product and process |
| US8889208B2 (en) | 2005-11-09 | 2014-11-18 | Wisconsin Alumni Research Foundation | Purification of beta casein from milk |
| NZ552352A (en) | 2006-12-22 | 2009-07-31 | Fonterra Co Operative Group | Dairy product produced from milk protein isolate or milk protein concentrate with reduced calcium and phosphate ion concentrations |
| NL1033698C2 (nl) | 2007-04-16 | 2008-10-20 | Friesland Brands Bv | Functioneel serumeiwitproduct voor toepassing in kindervoeding en therapeutische samenstellingen, en werkwijzen ter bereiding daarvan. |
| EP2217079B2 (en) | 2007-11-02 | 2021-06-02 | Select Milk Producers, Inc. | Methods for casein production |
| NL2006662C2 (en) * | 2011-04-26 | 2012-10-29 | Friesland Brands Bv | Method of making a milk protein composition. |
| FI125332B (fi) | 2011-11-11 | 2015-08-31 | Valio Oy | Menetelmä maitotuotteen valmistamiseksi |
| AU2014209964B2 (en) | 2013-01-23 | 2017-04-13 | Arla Foods Amba | Method of producing beta-casein compositions and related products |
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2014
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- 2014-01-23 EP EP16205408.4A patent/EP3172969A1/en active Pending
- 2014-01-23 KR KR1020157022768A patent/KR102268784B1/ko active IP Right Grant
- 2014-01-23 RU RU2015134776A patent/RU2668393C2/ru active
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- 2014-01-23 WO PCT/EP2014/051315 patent/WO2014114709A2/en active Application Filing
- 2014-01-23 EP EP14701187.8A patent/EP2947996B2/en active Active
- 2014-01-23 US US14/763,141 patent/US11470857B2/en active Active
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- 2014-01-23 ES ES14701187T patent/ES2620669T5/es active Active
- 2014-01-23 PT PT147011878T patent/PT2947996T/pt unknown
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2017
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| Publication number | Publication date |
|---|---|
| JP6426108B2 (ja) | 2018-11-21 |
| RU2018132526A3 (da) | 2022-04-12 |
| AU2014209964B2 (en) | 2017-04-13 |
| MX2015009390A (es) | 2016-04-06 |
| KR20150114968A (ko) | 2015-10-13 |
| KR102268784B1 (ko) | 2021-06-24 |
| ES2620669T3 (es) | 2017-06-29 |
| CN104981165A (zh) | 2015-10-14 |
| ES2620669T5 (es) | 2020-07-20 |
| RU2018132526A (ru) | 2019-03-19 |
| EP3172969A1 (en) | 2017-05-31 |
| EP2947996B1 (en) | 2016-12-21 |
| EP2947996B2 (en) | 2019-12-25 |
| RU2668393C2 (ru) | 2018-09-28 |
| EP2947996A2 (en) | 2015-12-02 |
| WO2014114709A2 (en) | 2014-07-31 |
| US20150359244A1 (en) | 2015-12-17 |
| RU2015134776A (ru) | 2017-03-02 |
| AU2014209964A1 (en) | 2015-07-23 |
| CA2897904A1 (en) | 2014-07-31 |
| BR112015017384B1 (pt) | 2020-11-10 |
| PT2947996T (pt) | 2017-03-29 |
| BR112015017384A2 (pt) | 2017-07-11 |
| WO2014114709A3 (en) | 2014-09-18 |
| CA2897904C (en) | 2022-09-06 |
| US11470857B2 (en) | 2022-10-18 |
| CN116869047A (zh) | 2023-10-13 |
| AU2017204173A1 (en) | 2017-07-13 |
| JP2016503660A (ja) | 2016-02-08 |
| DK2947996T4 (da) | 2020-03-02 |
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