DK2714147T3 - Medikamentfremføringsanordning med sensor for dispenseringsgrænseflade og fremgangsmåde til at styre anordningen - Google Patents

Medikamentfremføringsanordning med sensor for dispenseringsgrænseflade og fremgangsmåde til at styre anordningen Download PDF

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Publication number
DK2714147T3
DK2714147T3 DK12723204.9T DK12723204T DK2714147T3 DK 2714147 T3 DK2714147 T3 DK 2714147T3 DK 12723204 T DK12723204 T DK 12723204T DK 2714147 T3 DK2714147 T3 DK 2714147T3
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Denmark
Prior art keywords
cartridge
interface
delivery device
piston rod
drug delivery
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DK12723204.9T
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English (en)
Inventor
Ilona Eggert
Christopher Nigel Langley
Shane Alistair Day
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Sanofi Aventis Deutschland
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
    • A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/14—Detection of the presence or absence of a tube, a connector or a container in an apparatus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/60—General characteristics of the apparatus with identification means
    • A61M2205/6018—General characteristics of the apparatus with identification means providing set-up signals for the apparatus configuration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2066—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically comprising means for injection of two or more media, e.g. by mixing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2448—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic comprising means for injection of two or more media, e.g. by mixing

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Claims (14)

1. Medikamentfremføringsanordning (10) til administration af et eller flere lægemidler, hvilken anordning (10) omfatter: en medikamentpatronholder (50, 52) til at holde en medikamentpatron, et tilkoblingssted til tilkobling dertil af en dispenseringsgrænseflade, hvilken dispenseringsgrænseflade (200) er til tilvejebringelse af en udgangsvej for medikamentet, der er indeholdt i patronen, en grænsefladesensor (600), der er konfigureret til at tilvejebringe et output, der indikerer, om dispenseringsgrænsefladen (200) er tilkoblet til tilkoblingsstedet, og en stempelstang (627, 630) til at drive en spuns i medikamentpatronen, et drivsystem (624, 625) til fremføring af stempelstangen (627, 630) til spunsen, der er kendetegnet ved, - at anordningen (10) yderligere omfatter en styreenhed (700), der er konfigureret til at styre drivsystemet (624, 625) til fremføring af stempelstangen (627, 630) mod spunsen, når outputtet fra grænsefladesensoren (600) indikerer, at dispenseringsgrænsefladen (200) ikke er på tilkoblingsstedet, og til forhindring af fremføring af stempelstangen (627, 630), når outputtet fra grænsefladesensoren (600) indikerer, at dispenseringsgrænsefladen (200) er mindst delvist på tilkoblingsstedet, hvor styreenheden (700) er i stand til at registrere standsning af drivsystemet (624, 625), hvilken standsning af drivsystemet (624, 625) forekommer ved kontakt mellem stempelstangen (627, 630) og spunsen, og - hvor styreenheden (700) yderligere er konfigureret til at stoppe drivsystemet (624, 625), når standsning af drivsystemet (624, 625) registreres.
2. Medikamentfremføringsanordning ifølge krav 1, hvor styreenheden (700) er i stand til at overvåge outputsignalet fra grænsefladesensoren (600) under fremføring af stempelstangen (627, 630) og forhindre fremføring af stempelstangen (627, 630), hvis under fremføring deraf grænsefladesensoren (600) indikerer mindst delvis tilkobling af dispenseringsgrænsefladen (200).
3. Medikamentfremføringsanordning ifølge et hvilket som helst af ovennævnte krav, der omfatter en kodeenhed (633a, 633b), der er forbundet med drivsystemet (624, 625), hvilken kodeenhed (633a, 633b) er til tilvejebringelse af et output til styreenheden (700), hvor standsningen registreres afhængigt af outputtet fra kodeenheden.
4. Medikamentfremføringsanordning ifølge krav 3, hvor styreenheden (700) er i stand til at bestemme positionen af spunsen ved hjælp af overvågning af outputtet fra kodeenheden.
5. Medikamentfremføringsanordning ifølge et hvilket som helst af ovennævnte krav, der omfatter en første og anden medikamentpatronholder (50, 52) til hver at holde en medikamentpatron.
6. Medikamentfremføringsanordning ifølge krav 5, hvor dispenseringsgrænsefladen (200) tilvejebringer væskeforbindelse fra den første og anden medikamentpatronholder (50, 52) til et udløb fra anordningen (10) .
7. Medikamentfremføringsanordning ifølge et hvilket som helst af ovennævnte krav, hvor styreenheden (700) er i stand til at fremføre stempelstangen (627, 630) efter et patronskift.
8. Medikamentfremføringsanordning ifølge et hvilket som helst af ovennævnte krav, hvor anordningen (10) er håndholdt.
9. Medikamentfremføringsanordning ifølge krav 8, hvor anordningen (10) er en pentype injektionsanordning.
10. Medikamentfremføringsanordning ifølge et hvilket som helst af ovennævnte krav, hvor grænsefladesensoren (600) omfatter en første og en anden detektor (603, 604) til påvisning af delvis eller fuldstændig fjernelse af dispenseringsgrænsefladen (200) eller delvis eller fuldstændig tilkobling af dispenseringsgrænsefladen (200).
11. Medikamentfremføringsanordning ifølge krav 10, hvor den første detektor (603) aktiveres, når dispenseringsgrænsefladen (200) tilkobles delvist til tilkoblingsstedet, og den anden detektor (604) aktiveres, når dispenseringsgrænsefladen (200) tilkobles fuldstændigt til tilkoblingsstedet.
12. Medikamentfremføringsanordning ifølge krav 11, hvor den anden detektor (604) deaktiveres, når dispenseringsgrænsefladen (200) fjernes delvist, og den første detektor (603) deaktiveres, når dispenseringsgrænsefladen (200) fjernes fuldstændigt fra tilkoblingsstedet.
13. Fremgangsmåde til at styre en medikamentfremføringsanordning, især en medikamentfremføringsanordning (10) ifølge et af kravene 1 til 12, der omfatter en medikamentpatronholder (50, 52) til at holde en medikamentpatron, et tilkoblingssted til tilkobling dertil af en dispenseringsgrænseflade (200), hvilken dispenseringsgrænseflade (200) er til tilvejebringelse af en udgangsvej for medikamentet, der er indeholdt i patronen, en grænsefladesensor (600), der er konfigureret til at tilvejebringe et output, der indikerer, om dispenseringsgrænsefladen (200) er tilkoblet til tilkoblingsstedet, en stempelstang (627, 630) til at drive en spuns i medikamentpatronen, et drivsystem (624, 625) til fremføring af stempelstangen (627, 630) til spunsen og en styreenhed (700), der er konfigureret til at styre funktionen af anordningen (10), hvor styreenheden (700) er i stand til at registrere standsning af drivsystemet (624, 625), hvor standsningen af drivsystemet (624, 625) forekommer ved kontakt mellem stempelstangen (627, 630) og spunsen, hvilken fremgangsmåde omfatter: registrering af outputtet fra grænsefladesensoren (600); bestemmelse af, om det registrerede output indikerer, om dispenseringsgrænsefladen (200) er eller ikke er mindst delvist tilkoblet til tilkoblingsstedet; fremføring af stempelstangen (627, 630), når det registrerede output indikerer, at dispenseringsgrænsefladen (200) ikke er tilkoblet; standsning eller forhindring af fremføring af stempelstangen (627, 630), når outputtet fra grænsefladesensoren (600) indikerer, at dispenseringsgrænsefladen (200) er mindst delvist tilkoblet; og standsning af drivsystemet (624, 625), når standsning af drivsystemet (624, 625) registreres.
14. Fremgangsmåde ifølge krav 13, der omfatter registrering af standsning ved registrering af et output fra en kodeenhed (633a, 633b), der tilvejebringes i drivsystemet (624, 625).
DK12723204.9T 2011-05-25 2012-05-24 Medikamentfremføringsanordning med sensor for dispenseringsgrænseflade og fremgangsmåde til at styre anordningen DK2714147T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11167534 2011-05-25
PCT/EP2012/059752 WO2012160160A1 (en) 2011-05-25 2012-05-24 Medicament delivery device with dispense interface sensor and method controlling the device

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DK2714147T3 true DK2714147T3 (da) 2017-07-24

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US (1) US9492616B2 (da)
EP (1) EP2714147B1 (da)
JP (1) JP6050331B2 (da)
CN (1) CN103796696B (da)
DK (1) DK2714147T3 (da)
WO (1) WO2012160160A1 (da)

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JP2014516702A (ja) 2014-07-17
CN103796696B (zh) 2016-02-03
JP6050331B2 (ja) 2016-12-21
EP2714147B1 (en) 2017-04-12
WO2012160160A1 (en) 2012-11-29
US20140114277A1 (en) 2014-04-24
CN103796696A (zh) 2014-05-14
EP2714147A1 (en) 2014-04-09
US9492616B2 (en) 2016-11-15

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