DK235587A - Forstaerket transformantdyrecelle og fremgangsmaade til opnaaelse af samme samt anvendelse heraf til frembringelse af et oensket genprodukt - Google Patents
Forstaerket transformantdyrecelle og fremgangsmaade til opnaaelse af samme samt anvendelse heraf til frembringelse af et oensket genproduktInfo
- Publication number
- DK235587A DK235587A DK235587A DK235587A DK235587A DK 235587 A DK235587 A DK 235587A DK 235587 A DK235587 A DK 235587A DK 235587 A DK235587 A DK 235587A DK 235587 A DK235587 A DK 235587A
- Authority
- DK
- Denmark
- Prior art keywords
- reproduct
- getting
- procedures
- make
- same
- Prior art date
Links
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61105824A JP2585532B2 (ja) | 1986-05-10 | 1986-05-10 | 動物細胞の形質転換体及びそれを得る方法並びにその形質転換体を用いてt−PAを生産する方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK235587D0 DK235587D0 (da) | 1987-05-08 |
DK235587A true DK235587A (da) | 1987-11-11 |
Family
ID=14417809
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK235587A DK235587A (da) | 1986-05-10 | 1987-05-08 | Forstaerket transformantdyrecelle og fremgangsmaade til opnaaelse af samme samt anvendelse heraf til frembringelse af et oensket genprodukt |
Country Status (9)
Country | Link |
---|---|
US (1) | US5219738A (da) |
EP (1) | EP0246049B1 (da) |
JP (1) | JP2585532B2 (da) |
AU (1) | AU599977B2 (da) |
DE (1) | DE3787044T2 (da) |
DK (1) | DK235587A (da) |
FI (1) | FI872013A (da) |
NO (1) | NO871912L (da) |
ZA (1) | ZA873211B (da) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5550036A (en) * | 1986-04-09 | 1996-08-27 | Eli Lilly And Company | Method for co-amplification of human protein C genes in human cells |
EP0319206A3 (en) * | 1987-11-30 | 1990-04-18 | Berlex Laboratories, Inc. | Gene amplification |
AU4741090A (en) * | 1988-12-08 | 1990-06-26 | Damon Biotech Inc. | Expression induction method employing mutant dhfr gene |
US8962274B2 (en) * | 2009-02-27 | 2015-02-24 | Novartis Ag | Methods for selecting eukaryotic cells expressing a heterologous protein |
LT3412684T (lt) | 2013-07-31 | 2022-07-11 | Novartis Ag | Nauji atrankos vektoriai ir eukariotinių ląstelių šeimininkių atrankos metodai |
BR112016013420A2 (pt) | 2013-12-20 | 2017-09-26 | Novartis Ag | células eucarióticas e métodos para expressar recombinantemente um produto de interesse |
BR112016013443B1 (pt) | 2013-12-20 | 2022-11-29 | Novartis Ag | Métodos para produzir de forma recombinante um produto de interesse, para produção de uma célula hospedeira eucariótica para produzir de forma recombinante um produto de interesse, e para analisar as células eucarióticas quanto à sua adequabilidade como células hospedeiras para expressão recombinante de um produto de interesse |
JP6245299B2 (ja) * | 2016-04-27 | 2017-12-13 | バクスアルタ ゲーエムベーハー | 組換え安定細胞クローン、その産生およびその使用 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE223230C (da) * | ||||
US4399216A (en) * | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
IL68561A (en) * | 1982-05-05 | 1991-01-31 | Genentech Inc | Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof |
US4713339A (en) * | 1983-01-19 | 1987-12-15 | Genentech, Inc. | Polycistronic expression vector construction |
IE56716B1 (en) * | 1983-01-19 | 1991-11-20 | Genentech Inc | Method for producing human tpa and expression vectors therefor |
AU2353384A (en) * | 1983-01-19 | 1984-07-26 | Genentech Inc. | Amplification in eukaryotic host cells |
US4965199A (en) * | 1984-04-20 | 1990-10-23 | Genentech, Inc. | Preparation of functional human factor VIII in mammalian cells using methotrexate based selection |
IL71691A (en) * | 1984-04-27 | 1991-04-15 | Yeda Res & Dev | Production of interferon-ypsilon |
DE3668186D1 (de) * | 1985-04-01 | 1990-02-15 | Celltech Ltd | Transformierte myeloma-zell-linie und dieselbe verwendendes verfahren zur expression eines gens, das ein eukaryontisches polypeptid kodiert. |
JPH0714341B2 (ja) * | 1985-11-20 | 1995-02-22 | 鐘淵化学工業株式会社 | 蛋白質の高生産株の取得方法 |
-
1986
- 1986-05-10 JP JP61105824A patent/JP2585532B2/ja not_active Expired - Fee Related
-
1987
- 1987-05-04 US US07/045,512 patent/US5219738A/en not_active Expired - Fee Related
- 1987-05-05 ZA ZA873211A patent/ZA873211B/xx unknown
- 1987-05-06 FI FI872013A patent/FI872013A/fi not_active Application Discontinuation
- 1987-05-08 DK DK235587A patent/DK235587A/da not_active Application Discontinuation
- 1987-05-08 AU AU72650/87A patent/AU599977B2/en not_active Ceased
- 1987-05-08 NO NO871912A patent/NO871912L/no unknown
- 1987-05-11 DE DE87304152T patent/DE3787044T2/de not_active Expired - Fee Related
- 1987-05-11 EP EP87304152A patent/EP0246049B1/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP0246049A1 (en) | 1987-11-19 |
AU7265087A (en) | 1987-11-12 |
FI872013A (fi) | 1987-11-11 |
JPS62262988A (ja) | 1987-11-16 |
US5219738A (en) | 1993-06-15 |
AU599977B2 (en) | 1990-08-02 |
DE3787044T2 (de) | 1993-12-09 |
NO871912D0 (no) | 1987-05-08 |
DK235587D0 (da) | 1987-05-08 |
DE3787044D1 (de) | 1993-09-23 |
NO871912L (no) | 1987-11-11 |
FI872013A0 (fi) | 1987-05-06 |
ZA873211B (en) | 1987-10-28 |
EP0246049B1 (en) | 1993-08-18 |
JP2585532B2 (ja) | 1997-02-26 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |