DK2343052T3 - Hydrofil filtrering under fremstilling af vaccineadjuvanter - Google Patents

Hydrofil filtrering under fremstilling af vaccineadjuvanter

Info

Publication number
DK2343052T3
DK2343052T3 DK10252044.2T DK10252044T DK2343052T3 DK 2343052 T3 DK2343052 T3 DK 2343052T3 DK 10252044 T DK10252044 T DK 10252044T DK 2343052 T3 DK2343052 T3 DK 2343052T3
Authority
DK
Denmark
Prior art keywords
hydrophil
adjusters
filtering
preparing vaccine
vaccine
Prior art date
Application number
DK10252044.2T
Other languages
English (en)
Inventor
Gottfried Kraus
Robert Eskes
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43971135&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK2343052(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Application granted granted Critical
Publication of DK2343052T3 publication Critical patent/DK2343052T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F27/00—Mixers with rotary stirring devices in fixed receptacles; Kneaders
    • B01F27/27—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices
    • B01F27/271—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator
    • B01F27/2711—Mixers with stator-rotor systems, e.g. with intermeshing teeth or cylinders or having orifices with means for moving the materials to be mixed radially between the surfaces of the rotor and the stator provided with intermeshing elements
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F33/00—Other mixers; Mixing plants; Combinations of mixers
    • B01F33/80—Mixing plants; Combinations of mixers
    • B01F33/81—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles
    • B01F33/811—Combinations of similar mixers, e.g. with rotary stirring devices in two or more receptacles in two or more consecutive, i.e. successive, mixing receptacles or being consecutively arranged
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Colloid Chemistry (AREA)
DK10252044.2T 2009-12-03 2010-12-03 Hydrofil filtrering under fremstilling af vaccineadjuvanter DK2343052T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US28351709P 2009-12-03 2009-12-03

Publications (1)

Publication Number Publication Date
DK2343052T3 true DK2343052T3 (da) 2013-09-02

Family

ID=43971135

Family Applications (1)

Application Number Title Priority Date Filing Date
DK10252044.2T DK2343052T3 (da) 2009-12-03 2010-12-03 Hydrofil filtrering under fremstilling af vaccineadjuvanter

Country Status (22)

Country Link
US (3) US10213383B2 (da)
EP (3) EP2506832B1 (da)
JP (2) JP5754860B2 (da)
KR (2) KR101625623B1 (da)
CN (2) CN102858322B (da)
AU (1) AU2010325748B2 (da)
BR (1) BR112012013425A2 (da)
CA (1) CA2780425C (da)
CL (1) CL2012001268A1 (da)
DK (1) DK2343052T3 (da)
EA (1) EA025622B1 (da)
ES (3) ES2426969T3 (da)
HK (2) HK1159995A1 (da)
HR (1) HRP20130623T1 (da)
IL (1) IL219627B (da)
MX (1) MX2012005598A (da)
NZ (1) NZ599881A (da)
PL (1) PL2343052T3 (da)
PT (1) PT2343052E (da)
SG (1) SG10201501612RA (da)
SI (2) SI2506832T1 (da)
WO (1) WO2011067669A2 (da)

Families Citing this family (19)

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Publication number Priority date Publication date Assignee Title
CL2012001399A1 (es) 2009-12-03 2013-03-08 Novartis Ag Metodo para fabricar adyuvante para vacuna (emulsion aceite/agua con escualeno, polisorbato 80 y trioleato de sorbitan), que comprende (i) formar primera emulsion en homogenizador desde un contendor a otro para formar segunda emulsion, (ii) y microfluidizar primera emulsion para formar segunda emulsion.
CN102753149B (zh) 2009-12-03 2015-10-14 诺华股份有限公司 乳液微流化和/或均化期间的组分循环
SI2506833T1 (sl) † 2009-12-03 2014-07-31 Novartis Ag Sklop interakcijske in protitlaäśne komore za mikrofluidiziranje
DK2343052T3 (da) 2009-12-03 2013-09-02 Novartis Ag Hydrofil filtrering under fremstilling af vaccineadjuvanter
DE102009056884B4 (de) 2009-12-03 2021-03-18 Novartis Ag Impfstoff-Adjuvantien und verbesserte Verfahren zur Herstellung derselben
WO2011141819A1 (en) 2010-05-12 2011-11-17 Novartis Ag Improved methods for preparing squalene
GB201009676D0 (en) * 2010-06-10 2010-07-21 Glaxosmithkline Biolog Sa Novel process
CN103597068A (zh) * 2011-03-30 2014-02-19 独立行政法人国立长寿医疗研究中心 膜分选培养器、膜分选培养试剂盒、和使用其的干细胞分选方法、以及分离膜
WO2013132041A2 (en) 2012-03-08 2013-09-12 Novartis Ag Adjuvanted formulations of booster vaccines
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MX2015004652A (es) 2012-10-12 2015-08-05 Glaxosmithkline Biolog Sa Antigenos de pertusis acelulares no entrelazados para uso en vacunas de combinacion.
JP2016502994A (ja) 2012-12-18 2016-02-01 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ジフテリア及び／又は破傷風から防御するためのコンジュゲート
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EP3226904B1 (en) 2014-12-02 2019-03-06 Novartis AG Manufacture of surfactant-containing compositions
EP3393481A1 (en) * 2015-12-23 2018-10-31 Novartis Ag Oil-in-water emulsions including retinoic acid
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JP2023532944A (ja) * 2020-06-30 2023-08-01 セキラス ユーケー リミテッド 水中油型エマルジョンアジュバントの低温濾過
CN113876943A (zh) * 2020-07-03 2022-01-04 神州细胞工程有限公司 浓缩的水包油型亚微乳佐剂及其制备方法

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Also Published As

Publication number Publication date
IL219627A0 (en) 2012-07-31
US20190201337A1 (en) 2019-07-04
PL2343052T3 (pl) 2013-11-29
BR112012013425A2 (pt) 2020-11-03
CN102858322B (zh) 2015-04-29
JP5754860B2 (ja) 2015-07-29
EP2343052B1 (en) 2013-06-12
US20130129786A1 (en) 2013-05-23
HK1159995A1 (en) 2012-08-10
NZ599881A (en) 2014-01-31
KR101616735B1 (ko) 2016-04-29
US10213383B2 (en) 2019-02-26
EP2601933B1 (en) 2015-10-07
JP2015098499A (ja) 2015-05-28
CA2780425C (en) 2014-02-04
KR20120101652A (ko) 2012-09-14
HK1175407A1 (en) 2013-07-05
US10799454B2 (en) 2020-10-13
KR20150041812A (ko) 2015-04-17
EA025622B1 (ru) 2017-01-30
ES2461852T3 (es) 2014-05-21
PT2343052E (pt) 2013-08-28
EP2506832A2 (en) 2012-10-10
CN104688687A (zh) 2015-06-10
US20210077395A1 (en) 2021-03-18
CN102858322A (zh) 2013-01-02
CL2012001268A1 (es) 2012-08-03
MX2012005598A (es) 2012-05-29
EP2343052A1 (en) 2011-07-13
CA2780425A1 (en) 2011-06-09
AU2010325748B2 (en) 2014-04-17
WO2011067669A2 (en) 2011-06-09
ES2426969T3 (es) 2013-10-28
SI2506832T1 (sl) 2014-06-30
KR101625623B1 (ko) 2016-05-31
ES2558056T3 (es) 2016-02-01
IL219627B (en) 2018-05-31
HRP20130623T1 (en) 2013-09-30
SG10201501612RA (en) 2015-04-29
SI2601933T1 (sl) 2015-12-31
JP2013512890A (ja) 2013-04-18
AU2010325748A1 (en) 2012-05-31
EP2506832B1 (en) 2014-02-26
EA201270519A1 (ru) 2012-12-28
WO2011067669A3 (en) 2011-08-04
EP2601933A1 (en) 2013-06-12

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