DK2300003T3 - Forbindelser til anvendelse i behandling af skade forbundet med eksponering for en alkylerende art - Google Patents

Forbindelser til anvendelse i behandling af skade forbundet med eksponering for en alkylerende art

Info

Publication number
DK2300003T3
DK2300003T3 DK09805313.5T DK09805313T DK2300003T3 DK 2300003 T3 DK2300003 T3 DK 2300003T3 DK 09805313 T DK09805313 T DK 09805313T DK 2300003 T3 DK2300003 T3 DK 2300003T3
Authority
DK
Denmark
Prior art keywords
exposure
compounds
damage associated
treating damage
alkylating species
Prior art date
Application number
DK09805313.5T
Other languages
English (en)
Inventor
Brian J Day
Carl W White
Original Assignee
Nat Jewish Health
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nat Jewish Health filed Critical Nat Jewish Health
Application granted granted Critical
Publication of DK2300003T3 publication Critical patent/DK2300003T3/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/409—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having four such rings, e.g. porphine derivatives, bilirubin, biliverdine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK09805313.5T 2008-05-23 2009-05-26 Forbindelser til anvendelse i behandling af skade forbundet med eksponering for en alkylerende art DK2300003T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5591908P 2008-05-23 2008-05-23
PCT/US2009/045198 WO2010016965A2 (en) 2008-05-23 2009-05-26 Methods for treating injury associated with exposure to an alkylating species

Publications (1)

Publication Number Publication Date
DK2300003T3 true DK2300003T3 (da) 2014-05-26

Family

ID=41664134

Family Applications (1)

Application Number Title Priority Date Filing Date
DK09805313.5T DK2300003T3 (da) 2008-05-23 2009-05-26 Forbindelser til anvendelse i behandling af skade forbundet med eksponering for en alkylerende art

Country Status (13)

Country Link
US (2) US11382895B2 (da)
EP (2) EP2732817B1 (da)
JP (1) JP5608644B2 (da)
KR (2) KR20160036108A (da)
CN (1) CN102105146A (da)
AU (1) AU2009280042B2 (da)
CA (1) CA2725012C (da)
DK (1) DK2300003T3 (da)
ES (2) ES2600469T3 (da)
IL (1) IL209435A (da)
MX (1) MX2010012593A (da)
RU (1) RU2506083C2 (da)
WO (1) WO2010016965A2 (da)

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Publication number Priority date Publication date Assignee Title
EP2473171A2 (en) * 2009-09-02 2012-07-11 The Regents of the University of Colorado, a body corporate Methods of treating mitochondrial disorders using metalloporhyrins
JP2015500244A (ja) * 2011-12-02 2015-01-05 ザ・リージエンツ・オブ・ザ・ユニバーシテイ・オブ・コロラド、ア・ボデイー・コーポレイト メタロポルフィリン神経学処置
BR112016011632A2 (pt) * 2013-11-22 2017-08-08 Aeolus Sciences Inc Método para sintetizar um derivado de porfirina, método para sintetizar um composto, método para sintetizar um composto hidrato, método de síntese, recipiente compreendendo uma pluralidade de compostos, formulação farmacêutica, método para purificar um composto, cristal, e, forma cristalina de complexo [5,10,15,20-tetrakis(1,3-dietilimidazólio-2-il)porfirinato]manganês(iii) cloreto hidrato
RU2629602C1 (ru) * 2016-12-01 2017-08-30 Войсковая Часть 41598 Бициллин-3 как средство профилактики и ранней терапии острых поражений сернистым ипритом
RU2635504C1 (ru) * 2016-12-01 2017-11-13 Войсковая Часть 41598 Бензилпенициллина натриевая соль как средство профилактики и ранней терапии острых поражений сернистым ипритом
RU2635476C1 (ru) * 2016-12-02 2017-11-13 Войсковая Часть 41598 Бициллин-1 как средство профилактики и ранней терапии острых поражений сернистым ипритом
US20220000881A1 (en) * 2018-10-31 2022-01-06 Repurposed Therapeutics, Inc. Dba Defender Treatment of exposure to chlorine gas with scopolamine

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EP2300003A4 (en) 2012-04-04
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CN102105146A (zh) 2011-06-22
RU2010152638A (ru) 2012-06-27
IL209435A (en) 2015-04-30
CA2725012A1 (en) 2010-02-11
KR20160036108A (ko) 2016-04-01
EP2732817B1 (en) 2016-08-24
US20230000830A1 (en) 2023-01-05
MX2010012593A (es) 2011-03-04
JP2012507471A (ja) 2012-03-29
EP2300003B1 (en) 2014-03-05
EP2732817A1 (en) 2014-05-21
WO2010016965A9 (en) 2010-04-01
IL209435A0 (en) 2011-01-31
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CA2725012C (en) 2019-05-07
US20110136775A1 (en) 2011-06-09
KR20110017398A (ko) 2011-02-21
JP5608644B2 (ja) 2014-10-15
RU2506083C2 (ru) 2014-02-10
AU2009280042B2 (en) 2015-06-04
KR101646066B1 (ko) 2016-08-05
WO2010016965A2 (en) 2010-02-11
ES2600469T3 (es) 2017-02-09
US11382895B2 (en) 2022-07-12

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