DK2231633T3 - Antitumorale forbindelser - Google Patents
Antitumorale forbindelserInfo
- Publication number
- DK2231633T3 DK2231633T3 DK08864895.1T DK08864895T DK2231633T3 DK 2231633 T3 DK2231633 T3 DK 2231633T3 DK 08864895 T DK08864895 T DK 08864895T DK 2231633 T3 DK2231633 T3 DK 2231633T3
- Authority
- DK
- Denmark
- Prior art keywords
- antitumoral
- relations
- cancer
- compound
- treatment
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/45—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups
- C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
- C07C233/51—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/695—Silicon compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
- A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic System
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07123882 | 2007-12-20 | ||
PCT/EP2008/068049 WO2009080761A1 (en) | 2007-12-20 | 2008-12-19 | Antitumoral compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2231633T3 true DK2231633T3 (da) | 2014-01-20 |
Family
ID=40580474
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08865009.8T DK2231590T3 (da) | 2007-12-20 | 2008-12-19 | Antitumorforbindelser |
DK08864895.1T DK2231633T3 (da) | 2007-12-20 | 2008-12-19 | Antitumorale forbindelser |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK08865009.8T DK2231590T3 (da) | 2007-12-20 | 2008-12-19 | Antitumorforbindelser |
Country Status (27)
Country | Link |
---|---|
US (4) | US9187445B2 (da) |
EP (3) | EP2231633B1 (da) |
JP (3) | JP5529038B2 (da) |
KR (3) | KR101639772B1 (da) |
CN (4) | CN102190643B (da) |
AT (1) | ATE549313T1 (da) |
AU (2) | AU2008341670B2 (da) |
BR (2) | BRPI0821116B8 (da) |
CA (2) | CA2710087C (da) |
CY (1) | CY1117245T1 (da) |
DK (2) | DK2231590T3 (da) |
ES (3) | ES2384420T3 (da) |
HK (3) | HK1180678A1 (da) |
HR (2) | HRP20120464T1 (da) |
IL (3) | IL206396A (da) |
MX (2) | MX2010006796A (da) |
MY (3) | MY148651A (da) |
NZ (3) | NZ586013A (da) |
PL (2) | PL2231590T3 (da) |
PT (2) | PT2231633E (da) |
RS (2) | RS52343B (da) |
RU (3) | RU2528393C9 (da) |
SG (2) | SG170778A1 (da) |
SI (2) | SI2231590T1 (da) |
UA (3) | UA104281C2 (da) |
WO (2) | WO2009080761A1 (da) |
ZA (3) | ZA201004018B (da) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2231590T3 (da) | 2007-12-20 | 2012-07-09 | Pharma Mar Sa | Antitumorforbindelser |
JP6180115B2 (ja) * | 2012-01-05 | 2017-08-16 | 花王株式会社 | 刺激感緩和剤 |
PL2986607T3 (pl) | 2013-04-16 | 2017-11-30 | Idorsia Pharmaceuticals Ltd | Przeciwbakteryjne pochodne biaromatyczne |
GB201309807D0 (en) * | 2013-05-31 | 2013-07-17 | Pharma Mar Sau | Antibody drug conjugates |
CN108467378A (zh) * | 2017-02-23 | 2018-08-31 | 复旦大学 | 一种二氢吡喃酮类化合物及其制备方法和用途 |
JOP20190254A1 (ar) | 2017-04-27 | 2019-10-27 | Pharma Mar Sa | مركبات مضادة للأورام |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5142056A (en) * | 1989-05-23 | 1992-08-25 | Abbott Laboratories | Retroviral protease inhibiting compounds |
US4855086A (en) * | 1982-10-15 | 1989-08-08 | Burroughs Wellcome Co. | Novel pesticides, preparation and use |
JPS61109717A (ja) | 1984-11-02 | 1986-05-28 | Teruhiko Beppu | 抗腫瘍剤 |
EP0564561A4 (en) * | 1990-12-28 | 1994-08-10 | Georgia Tech Res Inst | Peptides ketoamides, ketoacids, and ketoesters |
JPH0539283A (ja) | 1991-01-31 | 1993-02-19 | Suntory Ltd | 新規物質S−59917a及びその製造方法 |
ZA938019B (en) | 1992-11-13 | 1995-04-28 | Upjohn Co | Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating HIV and other retroviruses |
US5523456A (en) * | 1994-09-29 | 1996-06-04 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
US5681847A (en) * | 1995-12-05 | 1997-10-28 | Harbor Branch Oceanographic Institution, Inc. | Methods of using discodermolide compounds |
US5834506A (en) | 1996-11-01 | 1998-11-10 | Warner-Lambert Company | Dihydropyrones with improved antiviral activity |
US5840974A (en) * | 1996-12-04 | 1998-11-24 | Britisch Biotech Pharmaceuticals, Ltd. | Metalloproteinase inhibitors |
AU773567B2 (en) | 1998-09-11 | 2004-05-27 | Warner-Lambert Company | HIV protease inhibitors |
US6380400B1 (en) | 1998-09-11 | 2002-04-30 | Victor Fedij | Methods of making dihydropyrone HIV protease inhibitors |
CA2401104A1 (en) * | 2000-04-04 | 2001-10-11 | Novartis Ag | Method for treating cells resistant to antineoplastic agents |
EP2082737B1 (en) * | 2002-03-04 | 2014-12-31 | Merck HDAC Research, LLC | Methods of inducing terminal differentiation |
AU2004263287B2 (en) | 2003-07-25 | 2009-02-12 | Novartis Ag | Substituted lactams and their use as anti-cancer agents |
US7446196B2 (en) | 2004-06-03 | 2008-11-04 | Kosan Biosciences, Incorporated | Leptomycin compounds |
RU2006142690A (ru) * | 2004-06-03 | 2008-06-10 | Козан Байосайенсиз Инкорпорейтед (Us) | Соединения лептомицина |
WO2007014423A1 (en) * | 2005-08-02 | 2007-02-08 | Medvet Science Pty, Ltd. | Exercise apparatus |
NZ573706A (en) | 2006-06-16 | 2011-09-30 | Pharma Mar Sa | Antitumoral dihydropyran-2-one compounds |
DK2231590T3 (da) | 2007-12-20 | 2012-07-09 | Pharma Mar Sa | Antitumorforbindelser |
-
2008
- 2008-12-19 DK DK08865009.8T patent/DK2231590T3/da active
- 2008-12-19 CN CN201110073931.0A patent/CN102190643B/zh active Active
- 2008-12-19 NZ NZ586013A patent/NZ586013A/en unknown
- 2008-12-19 CN CN200880121840.6A patent/CN101903367B/zh active Active
- 2008-12-19 CN CN2011100568656A patent/CN102174058A/zh active Pending
- 2008-12-19 BR BRPI0821116A patent/BRPI0821116B8/pt active IP Right Grant
- 2008-12-19 ES ES08865009T patent/ES2384420T3/es active Active
- 2008-12-19 AU AU2008341670A patent/AU2008341670B2/en active Active
- 2008-12-19 SI SI200830644T patent/SI2231590T1/sl unknown
- 2008-12-19 CA CA2710087A patent/CA2710087C/en active Active
- 2008-12-19 ES ES08864895.1T patent/ES2442140T3/es active Active
- 2008-12-19 MY MYPI2010002590A patent/MY148651A/en unknown
- 2008-12-19 RS RS20120242A patent/RS52343B/en unknown
- 2008-12-19 DK DK08864895.1T patent/DK2231633T3/da active
- 2008-12-19 SI SI200831122T patent/SI2231633T1/sl unknown
- 2008-12-19 KR KR1020157016575A patent/KR101639772B1/ko active IP Right Grant
- 2008-12-19 MX MX2010006796A patent/MX2010006796A/es active IP Right Grant
- 2008-12-19 ES ES13154647.5T patent/ES2578606T3/es active Active
- 2008-12-19 WO PCT/EP2008/068049 patent/WO2009080761A1/en active Application Filing
- 2008-12-19 MX MX2010006795A patent/MX2010006795A/es active IP Right Grant
- 2008-12-19 JP JP2010538765A patent/JP5529038B2/ja active Active
- 2008-12-19 RU RU2013112003/04A patent/RU2528393C9/ru active
- 2008-12-19 AU AU2008341671A patent/AU2008341671B2/en active Active
- 2008-12-19 UA UAA201009035A patent/UA104281C2/ru unknown
- 2008-12-19 MY MYPI2010002591A patent/MY155342A/en unknown
- 2008-12-19 RS RS20140007A patent/RS53140B/en unknown
- 2008-12-19 US US12/746,974 patent/US9187445B2/en active Active
- 2008-12-19 BR BRPI0821114A patent/BRPI0821114B8/pt active IP Right Grant
- 2008-12-19 SG SG201102163-1A patent/SG170778A1/en unknown
- 2008-12-19 PL PL08865009T patent/PL2231590T3/pl unknown
- 2008-12-19 WO PCT/EP2008/068065 patent/WO2009080769A1/en active Application Filing
- 2008-12-19 JP JP2010538769A patent/JP5727228B2/ja active Active
- 2008-12-19 NZ NZ586012A patent/NZ586012A/en unknown
- 2008-12-19 PL PL08864895T patent/PL2231633T3/pl unknown
- 2008-12-19 EP EP08864895.1A patent/EP2231633B1/en active Active
- 2008-12-19 PT PT88648951T patent/PT2231633E/pt unknown
- 2008-12-19 AT AT08865009T patent/ATE549313T1/de active
- 2008-12-19 EP EP08865009A patent/EP2231590B9/en active Active
- 2008-12-19 UA UAA201009034A patent/UA106967C2/uk unknown
- 2008-12-19 RU RU2010130253/04A patent/RU2489429C2/ru active
- 2008-12-19 CA CA2715203A patent/CA2715203C/en active Active
- 2008-12-19 KR KR1020107015968A patent/KR101579553B1/ko active IP Right Grant
- 2008-12-19 NZ NZ597526A patent/NZ597526A/en unknown
- 2008-12-19 EP EP13154647.5A patent/EP2597091B1/en active Active
- 2008-12-19 US US12/746,966 patent/US8710264B2/en active Active
- 2008-12-19 UA UAA201406894A patent/UA119963C2/uk unknown
- 2008-12-19 RU RU2010130180/04A patent/RU2493147C2/ru active
- 2008-12-19 MY MYPI2014002392A patent/MY164533A/en unknown
- 2008-12-19 SG SG201102164-9A patent/SG170779A1/en unknown
- 2008-12-19 KR KR1020107015965A patent/KR101541436B1/ko active IP Right Grant
- 2008-12-19 PT PT08865009T patent/PT2231590E/pt unknown
- 2008-12-19 CN CN2008801218410A patent/CN101903337B/zh active Active
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2010
- 2010-06-04 ZA ZA2010/04018A patent/ZA201004018B/en unknown
- 2010-06-04 ZA ZA2010/04017A patent/ZA201004017B/en unknown
- 2010-06-15 IL IL206396A patent/IL206396A/en active IP Right Grant
- 2010-06-15 IL IL206397A patent/IL206397A/en active IP Right Grant
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2011
- 2011-03-01 HK HK13107821.5A patent/HK1180678A1/zh unknown
- 2011-03-01 HK HK11102050.0A patent/HK1147990A1/xx unknown
- 2011-03-01 HK HK11102052.8A patent/HK1147998A1/xx unknown
- 2011-08-31 ZA ZA2011/06371A patent/ZA201106371B/en unknown
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2012
- 2012-06-01 HR HRP20120464AT patent/HRP20120464T1/hr unknown
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2013
- 2013-11-24 IL IL229594A patent/IL229594A/en active IP Right Grant
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2014
- 2014-01-08 HR HRP20140015AT patent/HRP20140015T1/hr unknown
- 2014-01-27 CY CY20141100069T patent/CY1117245T1/el unknown
- 2014-04-10 JP JP2014080887A patent/JP5860088B2/ja active Active
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2015
- 2015-08-12 US US14/824,699 patent/US9827257B2/en active Active
- 2015-08-12 US US14/824,690 patent/US9750759B2/en active Active
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