DK217889A - Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase - Google Patents

Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase Download PDF

Info

Publication number
DK217889A
DK217889A DK217889A DK217889A DK217889A DK 217889 A DK217889 A DK 217889A DK 217889 A DK217889 A DK 217889A DK 217889 A DK217889 A DK 217889A DK 217889 A DK217889 A DK 217889A
Authority
DK
Denmark
Prior art keywords
desacetoxycephalosporin
synthetase
coding
expression vectors
dna
Prior art date
Application number
DK217889A
Other languages
English (en)
Other versions
DK217889D0 (da
Inventor
Thomas Dominick Ingolia
Steven Kovacevic
James Robert Miller
Paul Luther Skatrud
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK217889D0 publication Critical patent/DK217889D0/da
Publication of DK217889A publication Critical patent/DK217889A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK217889A 1988-05-09 1989-05-03 Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase DK217889A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/192,273 US5070020A (en) 1988-05-09 1988-05-09 Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase

Publications (2)

Publication Number Publication Date
DK217889D0 DK217889D0 (da) 1989-05-03
DK217889A true DK217889A (da) 1989-11-13

Family

ID=22708994

Family Applications (1)

Application Number Title Priority Date Filing Date
DK217889A DK217889A (da) 1988-05-09 1989-05-03 Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase

Country Status (7)

Country Link
US (1) US5070020A (da)
EP (1) EP0341892A1 (da)
JP (1) JPH0227984A (da)
AU (1) AU622662B2 (da)
DK (1) DK217889A (da)
HU (1) HU209581B (da)
IL (1) IL90129A0 (da)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6709859B1 (en) 1986-01-31 2004-03-23 Beecham Group P.L.C. Chromosomal DNA Fragments Encoding Enzymes for Encoding B-Lactam Biosynthesis Enzymes, and Vector and Transformants for Their Expression
DE3789880T2 (de) * 1986-01-31 1994-09-08 Beecham Group Plc Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen.
CA2045951A1 (en) * 1990-07-06 1992-01-07 Steven Kovacevic Recombinant dna expression vectors and dna compounds that encode deacetylcephalosporin c synthase activity
US5318896A (en) * 1991-09-11 1994-06-07 Merck & Co., Inc. Recombinant expandase bioprocess for preparing 7-aminodesacetoxy cephalosporanic acid (7-ADCA)
CZ288721B6 (cs) * 1991-10-15 2001-08-15 Dsm Gist B. V. Biologický způsob výroby kyseliny 7-aminodeacetylcefalosporanové
US5554507A (en) * 1992-07-30 1996-09-10 American Cyanamid Company Bacillus subtilis siderophore genes
WO1995004149A1 (en) * 1993-07-30 1995-02-09 Gist-Brocades B.V. Process for the efficient production of 7-adca via 3-(carboxyethylthio)propionyl-7-adca
JPH09512170A (ja) * 1994-04-22 1997-12-09 メルク エンド カンパニー インコーポレーテッド セファマイシン生合成後期酵素コーディングｄｎａ
EP0777737B1 (en) * 1994-06-30 2005-05-04 Novozymes Biotech, Inc. Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein
DK0828850T3 (da) * 1995-06-02 2002-05-21 Dsm Nv Fremgangsmåde til fremstilling af 7-ADCA via indvirkning af en expandase på pencillin G
US5731165A (en) * 1995-06-02 1998-03-24 Gist-Brocades, B.V. Process for the production of 7-ADCA via expandase activity on penicillin G
US5919680A (en) * 1995-11-27 1999-07-06 Isis Innovation Limited Process for the production of SSC's via expandase activity on penicillin G
AU4114697A (en) * 1996-07-16 1998-02-09 Gist-Brocades B.V. Improved process for the production of adipoyl cephalosporins
US6136557A (en) * 1996-12-13 2000-10-24 Eli Lilly And Company Strepococcus pneumoniae gene sequence FtsH
WO1999060102A2 (en) * 1998-05-19 1999-11-25 Dsm N.V. Improved in vivo production of cephalosporins
US7094953B2 (en) 1998-05-29 2006-08-22 Iowa State University Research Foundation, Inc. Plant retroelements and methods related thereto
US6720479B1 (en) * 1998-05-29 2004-04-13 Iowa State University Research Foundation, Inc. Plant retroelements and methods related thereto
US6284483B1 (en) * 1999-10-06 2001-09-04 Board Of Trustees Operating Michigan State University Modified synthetases to produce penicillins and cephalosporins under the control of bicarbonate
WO2003000715A1 (en) * 2001-06-22 2003-01-03 Ceres, Inc. Chimeric histone acetyltransferase polypeptides
EP2360251B1 (en) 2001-07-12 2016-09-28 University of Massachusetts In vivo production of small interfering RNAs that mediate gene silencing
EP1900815B1 (en) 2001-07-12 2016-09-07 University of Massachusetts In vivo production of small interfering RNAs that mediate gene silencing
US6699699B2 (en) 2002-03-26 2004-03-02 Synmax Biochemical Co., Ltd. Mutated penicillin expandases
US20070093465A1 (en) 2003-05-28 2007-04-26 Van Den Berg Marco A Cephem compound
PL1633767T3 (pl) 2003-06-02 2019-07-31 University Of Massachusetts Sposoby i kompozycje do kontrolowania wydajności wyciszania rna
ES2864206T3 (es) 2003-06-02 2021-10-13 Univ Massachusetts Métodos y composiciones para mejorar la eficacia y la especificidad del ARNi
WO2007107810A1 (en) * 2006-03-20 2007-09-27 Council Of Scientific And Industrial Research A method for detecting the presence of water born pathogens and indicator microorganism
WO2010077806A1 (en) 2008-12-15 2010-07-08 Greenlight Biosciences, Inc. Methods for control of flux in metabolic pathways
CA2749877A1 (en) * 2008-12-22 2010-07-01 Greenlight Biosciences, Inc. Compositions and methods for the production of a compound
JP2013526277A (ja) 2010-05-07 2013-06-24 グリーンライト バイオサイエンシーズ インコーポレーテッド 酵素リロケーションにより代謝経路のフラックスを制御する方法
DK3219796T3 (da) 2010-08-31 2020-12-21 Greenlight Biosciences Inc Fremgangsmåder til kontrol af strømningen i metaboliske reaktionsveje ved hjælp af proteasemanipulation
JP2014526250A (ja) 2011-09-09 2014-10-06 グリーンライト バイオサイエンシーズ インコーポレーテッド カルバペネムの無細胞調製
EP3030671B1 (en) 2013-08-05 2018-10-03 Greenlight Biosciences, Inc. Engineered proteins with a protease cleavage site
CN107614682B (zh) 2015-03-30 2021-11-09 绿光生物科技股份有限公司 核糖核酸的无细胞生成
CA3020312A1 (en) 2016-04-06 2017-10-12 Greenlight Biosciences, Inc. Cell-free production of ribonucleic acid
MX2020003841A (es) 2017-10-11 2020-11-06 Greenlight Biosciences Inc Métodos y composiciones para la producción de nucleósido trifosfatos y ácidos ribonucleicos.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4510246A (en) * 1982-08-23 1985-04-09 Queen's University At Kingston Isolation of cyclase, epimerase and a ring expansion enzyme for producing unnatural cephalosporins
US4536476A (en) * 1982-08-23 1985-08-20 Queen's University At Kingston Stable epimerase reagent, cyclase reagent and ring expansion reagent for cell-free production of cephalosporins
DE3789880T2 (de) * 1986-01-31 1994-09-08 Beecham Group Plc Isolierung und Expression von bei der Biosynthese von Beta-Laktamen beteiligten Genen.

Also Published As

Publication number Publication date
HUT51672A (en) 1990-05-28
EP0341892A1 (en) 1989-11-15
HU209581B (en) 1994-08-29
IL90129A0 (en) 1989-12-15
DK217889D0 (da) 1989-05-03
AU3408289A (en) 1989-11-09
AU622662B2 (en) 1992-04-16
JPH0227984A (ja) 1990-01-30
US5070020A (en) 1991-12-03

Similar Documents

Publication Publication Date Title
DK217889D0 (da) Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for desacetoxycephalosporin c synthetase
GB8819209D0 (en) Polypeptide & dna encoding same
DK122687D0 (da) Polypeptid, dna og anvendelse deraf
DK108189A (da) Chimere antistoffer rettet mod humant carcinoembryonalt antigen og metal-chelater samt dna-sekvenser, der koder for saadanne antistoffer
DE3888921D1 (de) Polypeptide.
DK178386D0 (da) Rekombinant dna-udtrykkelsesvektor og dna-forbindelser, der udtrykker isopenicillin n synthetase
DK102088A (da) Rekombinant-dna-udtrykkelsesvektorer og dna-produkter, der koder deacetoxycephalosporin c syntetase og deacetylsephalosporin c synthetase
DK606088A (da) Rekombinant-dna-udtrykkelsesvektorer og dna-forbindelser, der koder for isopenicillin n synthetase
DK589085D0 (da) Rekombinant dna-udtrykkelsesvektor, der er funktionel og udvaelgelig iplanter
DK224985A (da) Peptider, og midler indeholdende peptiderne
GB8901892D0 (en) Nucloetide sequence encoding plant ribosome inactivating protein
FI841288A (fi) Rekombinant-dna-kod foer uttryckning av polypeptid.
DK35483D0 (da) Expressionsvectorer for catechol-2,3-oxygenase, de vundne enzymer og deres anvendelse
DK502988D0 (da) Polypeptider med interferon- eller interferon-gamma-lignende aktivitet, fremgangsmaade til fremstilling deraf, vektorer, der koder disse polypeptider og farmaceutiske praeparater indeholdende saadanne
DK258185A (da) Peptid og gen, der koder derfor
DK400786D0 (da) Udtrykkelsesvektorer til anvendelse i e.coli
NO842682L (no) Polypeptid og dna-sekvens samt vektor
NO890174D0 (no) Rekombinante interleukin-1alfa-polypeptider.
DK447083A (da) Dna, som koder for humant interferon-gamma, rekombinant-dna indeholdende denne dna, mikroorganisme indeholdende rekombinant-dna'en og fremgangsmaade til fremstilling af humant interferon-gamma-polypeptid
DK198188A (da) Rekombinant-dna-kloningsvektorer, der fremkalder spiramycin-resistens
DE3484304D1 (de) Streptokinase kodierende rekombinante vektoren.
DK146789D0 (da) Polypeptider med vaekstfaktoraktivitet og nucleinsyresekvenser, der koder for polypeptiderne
DK130290A (da) Lymfokiner, dna-sekvenser, som koder for disse lymfokiner og farmaceutiske midler indeholdende disse lymfokiner
IT8523165A0 (it) Peptidi correlati al lisozima.
IE882691L (en) Recombinant dna expression vectors

Legal Events

Date Code Title Description
ATS Application withdrawn