AU4114697A - Improved process for the production of adipoyl cephalosporins - Google Patents

Improved process for the production of adipoyl cephalosporins

Info

Publication number
AU4114697A
AU4114697A AU41146/97A AU4114697A AU4114697A AU 4114697 A AU4114697 A AU 4114697A AU 41146/97 A AU41146/97 A AU 41146/97A AU 4114697 A AU4114697 A AU 4114697A AU 4114697 A AU4114697 A AU 4114697A
Authority
AU
Australia
Prior art keywords
adipoyl
cephalosporins
production
improved process
improved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU41146/97A
Inventor
Roelof Ary Lans Bovenberg
Richard Kerkman
Maarten Nieboer
Jan Metske Van Der Laan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
DSM Delft BV
Original Assignee
Gist Brocades BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gist Brocades BV filed Critical Gist Brocades BV
Publication of AU4114697A publication Critical patent/AU4114697A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/02—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin by desacylation of the substituent in the 7 position

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AU41146/97A 1996-07-16 1997-07-15 Improved process for the production of adipoyl cephalosporins Abandoned AU4114697A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP96201988 1996-07-16
EP96201988 1996-07-16
PCT/EP1997/003879 WO1998002551A2 (en) 1996-07-16 1997-07-15 Process for the production of adipoyl cephalosporins

Publications (1)

Publication Number Publication Date
AU4114697A true AU4114697A (en) 1998-02-09

Family

ID=8224186

Family Applications (1)

Application Number Title Priority Date Filing Date
AU41146/97A Abandoned AU4114697A (en) 1996-07-16 1997-07-15 Improved process for the production of adipoyl cephalosporins

Country Status (3)

Country Link
AU (1) AU4114697A (en)
WO (1) WO1998002551A2 (en)
ZA (1) ZA976295B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6320069B1 (en) 1996-07-02 2001-11-20 Toray Industries, Inc. Production of optically active ketone
ZA983396B (en) * 1997-04-22 1998-10-27 Gist Brocades Bv A method for controlling the solubility of a beta-lactam nucleus
BR9804858A (en) * 1997-04-22 1999-08-24 Gist Brocades Bv B-lactam antibiotic preparation method
MXPA00011223A (en) 1998-05-19 2002-04-17 Dsm Nv Improved in vivo.
US6699699B2 (en) 2002-03-26 2004-03-02 Synmax Biochemical Co., Ltd. Mutated penicillin expandases
US20090087893A1 (en) * 2004-04-22 2009-04-02 Orchid Chemicals & Pharmaceutical Ltd. Modified Expandase Enzyme and its use
CN101040043B (en) * 2004-10-13 2014-05-28 中化帝斯曼制药有限公司荷兰公司 Mutant expandases
CN107304418B (en) * 2016-04-18 2022-08-26 百瑞全球有限公司 Penicillin expandase mutant, DNA encoding the mutant, kit containing the mutant and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5070020A (en) * 1988-05-09 1991-12-03 Eli Lilly And Company Recombinant dna expression vectors and dna compounds that encode deacetoxycephalosporin c synthetase
US5082772A (en) * 1988-10-24 1992-01-21 Eli Lilly And Company Process for preparing deacetylcephalosporin c
AU1097297A (en) * 1995-11-27 1997-06-19 Gist-Brocades B.V. Improved process for the production of semi-synthetic cephalosporins via expandase activity on penicillin

Also Published As

Publication number Publication date
WO1998002551A2 (en) 1998-01-22
ZA976295B (en) 1998-09-01
WO1998002551A3 (en) 1998-02-19

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