DK2017258T3 - Fremgangsmåde til fremstilling af en radioaktiv fluormærket organisk forbindelse - Google Patents

Fremgangsmåde til fremstilling af en radioaktiv fluormærket organisk forbindelse

Info

Publication number
DK2017258T3
DK2017258T3 DK07742894.4T DK07742894T DK2017258T3 DK 2017258 T3 DK2017258 T3 DK 2017258T3 DK 07742894 T DK07742894 T DK 07742894T DK 2017258 T3 DK2017258 T3 DK 2017258T3
Authority
DK
Denmark
Prior art keywords
compound
formula
organic compound
compound represented
column
Prior art date
Application number
DK07742894.4T
Other languages
English (en)
Inventor
Akio Hayashi
Fumie Kurosaki
Masahito Toyama
Toshiyuki Shinmura
Emi Kaneko
Original Assignee
Nihon Mediphysics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nihon Mediphysics Co Ltd filed Critical Nihon Mediphysics Co Ltd
Application granted granted Critical
Publication of DK2017258T3 publication Critical patent/DK2017258T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B59/00Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se
    • C07B59/001Acyclic or carbocyclic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C07C227/20Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters by hydrolysis of N-acylated amino-acids or derivatives thereof, e.g. hydrolysis of carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/48Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms of the same non-condensed ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/04Systems containing only non-condensed rings with a four-membered ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK07742894.4T 2006-05-11 2007-05-07 Fremgangsmåde til fremstilling af en radioaktiv fluormærket organisk forbindelse DK2017258T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2006132089 2006-05-11
PCT/JP2007/059459 WO2007132689A1 (ja) 2006-05-11 2007-05-07 放射性フッ素標識有機化合物の製造方法

Publications (1)

Publication Number Publication Date
DK2017258T3 true DK2017258T3 (da) 2012-07-09

Family

ID=38693787

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07742894.4T DK2017258T3 (da) 2006-05-11 2007-05-07 Fremgangsmåde til fremstilling af en radioaktiv fluormærket organisk forbindelse

Country Status (19)

Country Link
US (1) US7897811B2 (da)
EP (1) EP2017258B1 (da)
JP (1) JP4550141B2 (da)
KR (1) KR101317258B1 (da)
CN (1) CN101443307B (da)
AT (1) ATE549312T1 (da)
AU (1) AU2007251015B2 (da)
BR (1) BRPI0711144B1 (da)
CA (1) CA2651786C (da)
DK (1) DK2017258T3 (da)
ES (1) ES2380372T3 (da)
HK (1) HK1129884A1 (da)
IL (1) IL195187A (da)
NO (1) NO341173B1 (da)
NZ (1) NZ572936A (da)
PT (1) PT2017258E (da)
RU (1) RU2434846C2 (da)
TW (1) TWI389872B (da)
WO (1) WO2007132689A1 (da)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2428415C2 (ru) 2005-11-29 2011-09-10 Нихон Меди-Физикс Ко., Лтд. Соединение-предшественник органического соединения, меченного радиоактивным галогеном
NO345488B1 (no) * 2006-12-27 2021-03-01 Nihon Mediphysics Co Ltd Fremgangsmåte for fremstilling av forløperforbindelse for radioaktiv fluormerket organisk forbindelse
EP2119458B9 (en) 2007-02-13 2013-08-21 Nihon Medi-Physics Co., Ltd. Method for production of radiation diagnostic imaging agent
US8269035B2 (en) * 2007-12-19 2012-09-18 Nihon Medi-Physics Co., Ltd. Process for production of radioactive-fluorine-labeled organic compound
GB0812923D0 (en) * 2008-07-15 2008-08-20 Isis Innovation Preparation of flourine-labelled compounds
MX2013006050A (es) * 2010-11-29 2013-06-28 Ge Healthcare Ltd Preparacion de precursor de pet.
GB201021530D0 (en) * 2010-12-20 2011-02-02 Ge Healthcare Ltd Purification of precursor compound by crystallisation
MX2013007186A (es) * 2010-12-20 2013-07-12 Ge Healthcare Ltd Purificacion de compuesto precursor mediante cristalizacion.
GB201021523D0 (en) * 2010-12-20 2011-02-02 Ge Healthcare Ltd Process simplification for precursor compound
EP2793954B1 (en) * 2011-12-21 2020-10-21 GE Healthcare Limited 18f-fluciclovine compositions in citrate buffers
US11534494B2 (en) 2011-12-21 2022-12-27 Ge Healthcare Limited Formulation and method of synthesis
GB201411569D0 (en) 2014-06-30 2014-08-13 Ge Healthcare Ltd Novel formulation and method of synthesis
GB201214220D0 (en) * 2012-08-09 2012-09-19 Ge Healthcare Ltd Radiosynthesis
GB2561122B (en) * 2012-12-21 2019-07-17 Ge Healthcare Ltd Composition comprising [18F]-Fluciclovine
GB201305687D0 (en) 2013-03-28 2013-05-15 Ge Healthcare Ltd Radiolabelling process
JP6755862B2 (ja) * 2015-06-05 2020-09-16 日本メジフィジックス株式会社 放射性標識化合物の製造装置及び製造方法
JP6485914B2 (ja) * 2015-10-28 2019-03-20 日本メジフィジックス株式会社 フルテメタモルの製造方法
CN106770883B (zh) * 2017-01-03 2019-01-29 原子高科股份有限公司 一种氟[18f]化钠注射液放化纯的薄层色谱分析方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5808146A (en) 1995-11-09 1998-09-15 Emory University Amino acid analogs for tumor imaging
BE1010280A3 (fr) 1996-05-02 1998-05-05 Coincidence S A Procede et dispositif de synthese de 2-[18f] fluoro-2-deoxy-d-glucose.
GB0229695D0 (en) 2002-12-20 2003-01-29 Amersham Plc Solid-phase preparation of 18F-labelled amino acids
WO2005030677A1 (ja) 2003-09-30 2005-04-07 Nihon Medi-Physics Co., Ltd. 放射性フッ素化合物の製造方法

Also Published As

Publication number Publication date
TWI389872B (zh) 2013-03-21
EP2017258A4 (en) 2011-05-25
NO341173B1 (no) 2017-09-04
EP2017258B1 (en) 2012-03-14
KR20090034805A (ko) 2009-04-08
HK1129884A1 (en) 2009-12-11
RU2008148851A (ru) 2010-06-20
BRPI0711144A2 (pt) 2011-08-23
US20090198085A1 (en) 2009-08-06
JPWO2007132689A1 (ja) 2009-09-24
CA2651786C (en) 2014-11-04
IL195187A (en) 2013-04-30
RU2434846C2 (ru) 2011-11-27
IL195187A0 (en) 2009-08-03
US7897811B2 (en) 2011-03-01
TW200811084A (en) 2008-03-01
AU2007251015A1 (en) 2007-11-22
NZ572936A (en) 2011-01-28
AU2007251015B2 (en) 2011-09-01
WO2007132689A1 (ja) 2007-11-22
CN101443307B (zh) 2012-05-16
BRPI0711144B1 (pt) 2017-03-28
ES2380372T3 (es) 2012-05-11
EP2017258A1 (en) 2009-01-21
PT2017258E (pt) 2012-04-12
CN101443307A (zh) 2009-05-27
ATE549312T1 (de) 2012-03-15
CA2651786A1 (en) 2007-11-22
NO20085076L (no) 2009-02-10
KR101317258B1 (ko) 2013-10-14
JP4550141B2 (ja) 2010-09-22

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