DK1974017T4 - Midler og fremgangsmåder til at påvirke stabiliteten af antistof producerende celler - Google Patents
Midler og fremgangsmåder til at påvirke stabiliteten af antistof producerende celler Download PDFInfo
- Publication number
- DK1974017T4 DK1974017T4 DK06824300.5T DK06824300T DK1974017T4 DK 1974017 T4 DK1974017 T4 DK 1974017T4 DK 06824300 T DK06824300 T DK 06824300T DK 1974017 T4 DK1974017 T4 DK 1974017T4
- Authority
- DK
- Denmark
- Prior art keywords
- affecting
- stability
- methods
- producing cells
- antibody producing
- Prior art date
Links
- 210000000628 antibody-producing cell Anatomy 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0635—B lymphocytes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/231—Interleukin-10 (IL-10)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2321—Interleukin-21 (IL-21)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/50—Cell markers; Cell surface determinants
- C12N2501/52—CD40, CD40-ligand (CD154)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/60—Transcription factors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/99—Coculture with; Conditioned medium produced by genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/02—Cells for production
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2510/00—Genetically modified cells
- C12N2510/04—Immortalised cells
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/NL2005/000848 WO2007067032A1 (en) | 2005-12-09 | 2005-12-09 | Means and methods for influencing the stability of cells |
EP06076211 | 2006-06-12 | ||
PCT/NL2006/000625 WO2007067046A1 (en) | 2005-12-09 | 2006-12-08 | Means and methods for influencing the stability of antibody producing cells |
Publications (2)
Publication Number | Publication Date |
---|---|
DK1974017T3 DK1974017T3 (da) | 2014-02-10 |
DK1974017T4 true DK1974017T4 (da) | 2023-09-25 |
Family
ID=37714656
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12175198.6T DK2540820T3 (da) | 2005-12-09 | 2006-12-08 | Midler og fremgangsmåder til påvirkning af stabiliteten af antistofproducerende celler |
DK06824300.5T DK1974017T4 (da) | 2005-12-09 | 2006-12-08 | Midler og fremgangsmåder til at påvirke stabiliteten af antistof producerende celler |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK12175198.6T DK2540820T3 (da) | 2005-12-09 | 2006-12-08 | Midler og fremgangsmåder til påvirkning af stabiliteten af antistofproducerende celler |
Country Status (14)
Country | Link |
---|---|
US (3) | US9127251B2 (da) |
EP (3) | EP2540820B1 (da) |
JP (2) | JP5753339B2 (da) |
AU (2) | AU2006323315B2 (da) |
BR (2) | BR122021001906B1 (da) |
CA (2) | CA3015416C (da) |
DK (2) | DK2540820T3 (da) |
ES (2) | ES2660899T3 (da) |
FI (1) | FI1974017T4 (da) |
HU (1) | HUE037580T2 (da) |
NZ (3) | NZ569543A (da) |
PL (2) | PL1974017T5 (da) |
PT (2) | PT2540820T (da) |
WO (1) | WO2007067046A1 (da) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
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PT2540820T (pt) | 2005-12-09 | 2018-03-02 | Academisch Medisch Centrum Bij De Univ Van Amsterdam | Meios e métodos para influenciar a establidade de células produtoras de anticorpos |
WO2007067032A1 (en) | 2005-12-09 | 2007-06-14 | Academisch Medisch Cemtrum Bij De Universiteit Van Amsterdam | Means and methods for influencing the stability of cells |
EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
JP5205597B2 (ja) * | 2007-06-01 | 2013-06-05 | 静岡県 | 1細胞レベルでの抗体遺伝子の解析・同定方法 |
WO2009020923A1 (en) * | 2007-08-03 | 2009-02-12 | Musc Foundation For Research Development | Human monoclonal antibodies and methods for producing the same |
US20110171688A1 (en) * | 2008-06-16 | 2011-07-14 | Christoph Esslinger | Method of providing immunoglobulin secreting b lymphocytes and human antibodies |
BRPI1012749B1 (pt) | 2009-05-11 | 2022-01-11 | Janssen Vaccines & Prevention B.V. | Anticorpo monoclonal humano, seu uso e seu método de produção, imunoconjugado, e composição farmacêutica |
JP5781508B2 (ja) | 2009-07-15 | 2015-09-24 | アイム・セラピューティクス・べー・フェー | 高親和性抗体を産生させるための手段および方法 |
US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
EP3037435B1 (en) | 2009-11-17 | 2019-08-07 | MUSC Foundation for Research Development | Human monoclonal antibodies to human nucleolin |
PL2400298T3 (pl) * | 2010-05-28 | 2014-01-31 | Hoffmann La Roche | Sposób hodowania pojedynczych komórek b oraz wytwarzania swoistych przeciwciał |
CN103429615B (zh) | 2010-12-02 | 2018-03-16 | 埃姆医疗有限公司 | 用于生产高亲和力抗体的方式和方法 |
KR20140112495A (ko) | 2011-12-02 | 2014-09-23 | 에임 쎄라퓨틱스 비.브이. | 인플루엔자 a 바이러스 특이적 항체 |
US10017739B2 (en) * | 2012-09-06 | 2018-07-10 | Duke University | Methods of expanding and assessing B cells and using expanded B cells to treat disease |
US10240125B2 (en) | 2013-03-14 | 2019-03-26 | Immusoft Corporation | Methods for in vitro memory B cell differentiation and transduction with VSV-G pseudotyped viral vectors |
MX2016008109A (es) | 2013-12-17 | 2017-01-13 | Aimm Therapeutics Bv | Medios y metodos para contrarrestar trastornos mieloproliferativos o linfoproliferativos. |
ES2927905T3 (es) * | 2013-12-24 | 2022-11-11 | Kling Biotherapeutics B V | Producción de anticuerpos ex vivo |
EP3099709B1 (en) | 2014-01-31 | 2019-12-25 | AIMM Therapeutics B.V. | Means and methods for producing stable antibodies |
AU2015268982B2 (en) * | 2014-06-05 | 2021-11-04 | Kling Biotherapeutics B.V. | Means and methods for determining T cell recognition |
WO2016002760A1 (ja) | 2014-07-02 | 2016-01-07 | 学校法人東京理科大学 | B細胞集団の製造方法 |
WO2016100932A1 (en) * | 2014-12-19 | 2016-06-23 | Immusoft Corporation | B cells for in vivo delivery of therapeutic agents |
EP3277823B1 (en) * | 2015-04-03 | 2023-09-13 | Dana-Farber Cancer Institute, Inc. | Composition and methods of genome editing of b-cells |
EP3307070A4 (en) * | 2015-06-12 | 2019-01-02 | Emory University | Growth and survival compositions for cells capable of producing antibodies and methods related thereto |
MX2017016258A (es) | 2015-06-24 | 2018-04-20 | Aimm Therapeutics Bv | Antigenos de leucemia mieloide aguda (aml) y usos de los mismos. |
JP7036729B2 (ja) | 2016-01-08 | 2022-03-15 | クリング・バイオセラピューティックス・べー・フェー | 治療用抗cd9抗体 |
WO2018102612A1 (en) | 2016-12-02 | 2018-06-07 | Juno Therapeutics, Inc. | Engineered b cells and related compositions and methods |
CA3051466A1 (en) | 2017-01-31 | 2018-08-09 | Vanderbilt University | Generation of human allergen-and helminth-specific ige monoclonal antibodies for diagnostic and therapeutic use |
US11125757B2 (en) | 2017-05-26 | 2021-09-21 | Emory University | Methods of culturing and characterizing antibody secreting cells |
US20210317187A1 (en) * | 2017-12-05 | 2021-10-14 | Sqz Biotechnologies Company | Intracellular delivery of biomolecules to modulate antibody production |
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JP5781508B2 (ja) | 2009-07-15 | 2015-09-24 | アイム・セラピューティクス・べー・フェー | 高親和性抗体を産生させるための手段および方法 |
NZ599148A (en) | 2009-10-06 | 2014-08-29 | Medimmune Ltd | Rsv-specific binding molecule |
US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
CN103429615B (zh) | 2010-12-02 | 2018-03-16 | 埃姆医疗有限公司 | 用于生产高亲和力抗体的方式和方法 |
KR20140112495A (ko) | 2011-12-02 | 2014-09-23 | 에임 쎄라퓨틱스 비.브이. | 인플루엔자 a 바이러스 특이적 항체 |
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2006
- 2006-12-08 PT PT121751986T patent/PT2540820T/pt unknown
- 2006-12-08 NZ NZ56954306A patent/NZ569543A/xx unknown
- 2006-12-08 US US12/086,328 patent/US9127251B2/en active Active
- 2006-12-08 CA CA3015416A patent/CA3015416C/en active Active
- 2006-12-08 CA CA2633157A patent/CA2633157C/en active Active
- 2006-12-08 EP EP12175198.6A patent/EP2540820B1/en active Active
- 2006-12-08 NZ NZ60007506A patent/NZ600075A/en unknown
- 2006-12-08 NZ NZ59215906A patent/NZ592159A/xx unknown
- 2006-12-08 DK DK12175198.6T patent/DK2540820T3/da active
- 2006-12-08 BR BR122021001906-1A patent/BR122021001906B1/pt active IP Right Grant
- 2006-12-08 FI FIEP06824300.5T patent/FI1974017T4/fi active
- 2006-12-08 EP EP18150705.4A patent/EP3327117A1/en active Pending
- 2006-12-08 AU AU2006323315A patent/AU2006323315B2/en active Active
- 2006-12-08 HU HUE12175198A patent/HUE037580T2/hu unknown
- 2006-12-08 PT PT06824300T patent/PT1974017E/pt unknown
- 2006-12-08 PL PL06824300.5T patent/PL1974017T5/pl unknown
- 2006-12-08 EP EP06824300.5A patent/EP1974017B2/en active Active
- 2006-12-08 DK DK06824300.5T patent/DK1974017T4/da active
- 2006-12-08 PL PL12175198T patent/PL2540820T3/pl unknown
- 2006-12-08 BR BRPI0619579A patent/BRPI0619579B8/pt active IP Right Grant
- 2006-12-08 WO PCT/NL2006/000625 patent/WO2007067046A1/en active Application Filing
- 2006-12-08 ES ES12175198.6T patent/ES2660899T3/es active Active
- 2006-12-08 ES ES06824300T patent/ES2444465T5/es active Active
- 2006-12-08 JP JP2008544276A patent/JP5753339B2/ja active Active
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2013
- 2013-02-05 JP JP2013020744A patent/JP5753547B2/ja active Active
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2014
- 2014-05-19 AU AU2014202709A patent/AU2014202709B2/en active Active
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2015
- 2015-08-26 US US14/836,335 patent/US9822339B2/en active Active
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2017
- 2017-06-02 US US15/612,096 patent/US10273454B2/en active Active
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