DK1896485T3 - Azolopyridin-2-on-derivater som inhibitorer af lipaser og phospholipaser - Google Patents

Azolopyridin-2-on-derivater som inhibitorer af lipaser og phospholipaser

Info

Publication number
DK1896485T3
DK1896485T3 DK06753937.9T DK06753937T DK1896485T3 DK 1896485 T3 DK1896485 T3 DK 1896485T3 DK 06753937 T DK06753937 T DK 06753937T DK 1896485 T3 DK1896485 T3 DK 1896485T3
Authority
DK
Denmark
Prior art keywords
azolopyridin
phospholipases
lipases
inhibitors
derivatives
Prior art date
Application number
DK06753937.9T
Other languages
English (en)
Inventor
Gerhard Zoller
Stefan Petry
Guenter Mueller
Hubert Heuer
Norbert Tennagels
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Application granted granted Critical
Publication of DK1896485T3 publication Critical patent/DK1896485T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/424—Oxazoles condensed with heterocyclic ring systems, e.g. clavulanic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK06753937.9T 2005-06-09 2006-05-27 Azolopyridin-2-on-derivater som inhibitorer af lipaser og phospholipaser DK1896485T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005026762A DE102005026762A1 (de) 2005-06-09 2005-06-09 Azolopyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholipasen
PCT/EP2006/005095 WO2006131231A1 (de) 2005-06-09 2006-05-27 Azolopyridin-2-on-derivate als inhibitoren von lipasen und phospholipasen

Publications (1)

Publication Number Publication Date
DK1896485T3 true DK1896485T3 (da) 2010-09-06

Family

ID=37076291

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06753937.9T DK1896485T3 (da) 2005-06-09 2006-05-27 Azolopyridin-2-on-derivater som inhibitorer af lipaser og phospholipaser

Country Status (30)

Country Link
US (2) US7846943B2 (da)
EP (1) EP1896485B1 (da)
JP (1) JP2008542410A (da)
KR (1) KR20080019215A (da)
CN (1) CN101193896A (da)
AR (1) AR054132A1 (da)
AT (1) ATE468342T1 (da)
AU (1) AU2006257022A1 (da)
BR (1) BRPI0611688A2 (da)
CA (1) CA2610325A1 (da)
CY (1) CY1110213T1 (da)
DE (2) DE102005026762A1 (da)
DK (1) DK1896485T3 (da)
ES (1) ES2346561T3 (da)
HR (1) HRP20100409T1 (da)
IL (1) IL187730A0 (da)
MA (1) MA29481B1 (da)
MX (1) MX2007015347A (da)
MY (1) MY142792A (da)
NO (1) NO20080133L (da)
NZ (1) NZ564063A (da)
PL (1) PL1896485T3 (da)
PT (1) PT1896485E (da)
RS (1) RS51268B (da)
RU (1) RU2414473C2 (da)
SI (1) SI1896485T1 (da)
TW (1) TW200716653A (da)
UY (1) UY29593A1 (da)
WO (1) WO2006131231A1 (da)
ZA (1) ZA200709501B (da)

Families Citing this family (8)

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DE102006014685A1 (de) * 2006-03-28 2007-10-04 Sanofi-Aventis Imidazo-pyridin-2-on-derivate als Inhibitoren von Lipasen und Phospholiphasen
EP2025674A1 (de) 2007-08-15 2009-02-18 sanofi-aventis Substituierte Tetrahydronaphthaline, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
UY31968A (es) 2008-07-09 2010-01-29 Sanofi Aventis Nuevos derivados heterocíclicos, sus procesos para su preparación, y sus usos terapéuticos
JP5605844B2 (ja) 2008-10-17 2014-10-15 塩野義製薬株式会社 血管内皮リパーゼ阻害活性を有する酢酸アミド誘導体
EP2493888B1 (en) * 2009-10-29 2016-04-06 GlaxoSmithKline LLC Bicyclic pyridines and analogs as sirtuin modulators
US8754113B2 (en) 2009-12-15 2014-06-17 Shionogi & Co., Ltd. Oxadiazole derivative having endothelial lipase inhibitory activity
WO2011157827A1 (de) 2010-06-18 2011-12-22 Sanofi Azolopyridin-3-on-derivate als inhibitoren von lipasen und phospholipasen
CN114560873B (zh) * 2021-12-27 2023-02-28 浙江日出药业有限公司 一种3-氯甲基-6-氯-噁唑[4,5-b]吡啶-2(3H)酮的制备方法

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Also Published As

Publication number Publication date
ATE468342T1 (de) 2010-06-15
MA29481B1 (fr) 2008-05-02
KR20080019215A (ko) 2008-03-03
IL187730A0 (en) 2008-08-07
HRP20100409T1 (hr) 2010-09-30
US20110039883A1 (en) 2011-02-17
US20080167339A1 (en) 2008-07-10
EP1896485A1 (de) 2008-03-12
BRPI0611688A2 (pt) 2010-09-28
AU2006257022A1 (en) 2006-12-14
NO20080133L (no) 2008-03-05
AR054132A1 (es) 2007-06-06
MY142792A (en) 2010-12-31
PL1896485T3 (pl) 2010-10-29
ZA200709501B (en) 2008-10-29
SI1896485T1 (sl) 2010-09-30
CN101193896A (zh) 2008-06-04
UY29593A1 (es) 2007-01-31
MX2007015347A (es) 2008-02-15
TW200716653A (en) 2007-05-01
DE502006006986D1 (de) 2010-07-01
DE102005026762A1 (de) 2006-12-21
US7846943B2 (en) 2010-12-07
CA2610325A1 (en) 2006-12-14
RU2414473C2 (ru) 2011-03-20
JP2008542410A (ja) 2008-11-27
RU2007145499A (ru) 2009-06-20
ES2346561T3 (es) 2010-10-18
WO2006131231A1 (de) 2006-12-14
NZ564063A (en) 2010-07-30
CY1110213T1 (el) 2012-05-23
RS51268B (sr) 2010-12-31
EP1896485B1 (de) 2010-05-19
PT1896485E (pt) 2010-08-05

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