DK175859B1 - Peroralt præparat til administrering af bioaktive midler via de Peyerske plaques samt anvendelse af et antigen til fremstilling af et peroralt præparat - Google Patents

Peroralt præparat til administrering af bioaktive midler via de Peyerske plaques samt anvendelse af et antigen til fremstilling af et peroralt præparat Download PDF

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Publication number
DK175859B1
DK175859B1 DK198705577A DK557787A DK175859B1 DK 175859 B1 DK175859 B1 DK 175859B1 DK 198705577 A DK198705577 A DK 198705577A DK 557787 A DK557787 A DK 557787A DK 175859 B1 DK175859 B1 DK 175859B1
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DK
Denmark
Prior art keywords
antigen
composition according
plaques
microcapsules
diameter
Prior art date
Application number
DK198705577A
Other languages
Danish (da)
English (en)
Other versions
DK557787D0 (da
DK557787A (da
Inventor
Thomas R Tice
Richard M Gilley
Jay K Staas
John H Eldridge
Original Assignee
Uab Research Foundation
Southern Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
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Application filed by Uab Research Foundation, Southern Res Inst filed Critical Uab Research Foundation
Publication of DK557787D0 publication Critical patent/DK557787D0/da
Publication of DK557787A publication Critical patent/DK557787A/da
Application granted granted Critical
Publication of DK175859B1 publication Critical patent/DK175859B1/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/44—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK198705577A 1986-10-24 1987-10-23 Peroralt præparat til administrering af bioaktive midler via de Peyerske plaques samt anvendelse af et antigen til fremstilling af et peroralt præparat DK175859B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US92315986A 1986-10-24 1986-10-24
US92315986 1986-10-24
CN95100893A CN1111157A (zh) 1986-10-24 1995-03-08 用于到达派亚氏***的口服生物活性剂的制法和配方
CN95100893 1995-03-08

Publications (3)

Publication Number Publication Date
DK557787D0 DK557787D0 (da) 1987-10-23
DK557787A DK557787A (da) 1988-04-25
DK175859B1 true DK175859B1 (da) 2005-04-11

Family

ID=36954601

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198705577A DK175859B1 (da) 1986-10-24 1987-10-23 Peroralt præparat til administrering af bioaktive midler via de Peyerske plaques samt anvendelse af et antigen til fremstilling af et peroralt præparat

Country Status (15)

Country Link
EP (1) EP0266119B2 (xx)
JP (1) JP2741728B2 (xx)
KR (1) KR900003559B1 (xx)
CN (1) CN1111157A (xx)
AT (1) ATE108650T1 (xx)
AU (1) AU607439B2 (xx)
CA (1) CA1331738C (xx)
DE (1) DE3750247T2 (xx)
DK (1) DK175859B1 (xx)
ES (1) ES2056068T3 (xx)
HK (1) HK122495A (xx)
IE (1) IE64786B1 (xx)
IL (1) IL84167A (xx)
NZ (1) NZ222278A (xx)
ZA (1) ZA877946B (xx)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ217821A (en) * 1985-10-10 1989-07-27 Biotech Australia Pty Ltd Oral delivery system; complex of active agent and vitamin b12 or analogue thereof
US5075109A (en) * 1986-10-24 1991-12-24 Southern Research Institute Method of potentiating an immune response
US6024983A (en) * 1986-10-24 2000-02-15 Southern Research Institute Composition for delivering bioactive agents for immune response and its preparation
US5807832A (en) * 1987-06-09 1998-09-15 Biotech Australia Pty Limited Oral delivery of biologically active substances bound to vitamin B12
JP2664906B2 (ja) * 1987-08-13 1997-10-22 ストール・リサーチ・アンド・デイベロップメント・コーポレーション 改良された哺乳類の免疫法
US5444113A (en) * 1988-08-08 1995-08-22 Ecopol, Llc End use applications of biodegradable polymers
EP0550436A1 (en) * 1989-11-06 1993-07-14 Alkermes Controlled Therapeutics, Inc. Protein microspheres and methods of using them
JP3249147B2 (ja) * 1990-06-01 2002-01-21 キリン−アムジエン・インコーポレーテツド 生理活性蛋白含有経口製剤
ATE156705T1 (de) * 1991-04-02 1997-08-15 Biotech Australia Pty Ltd Systeme zur oralen freisetzung von mikropartikeln
US5912015A (en) 1992-03-12 1999-06-15 Alkermes Controlled Therapeutics, Inc. Modulated release from biocompatible polymers
US6514533B1 (en) 1992-06-11 2003-02-04 Alkermas Controlled Therapeutics, Inc. Device for the sustained release of aggregation-stabilized, biologically active agent
AU4932493A (en) * 1992-09-25 1994-04-26 Dynagen, Inc. An immunobooster for delayed release of immunogen
DK0724433T3 (da) * 1993-10-22 1999-08-30 Genentech Inc Fremgangsmåde til fremstilling af mikrosfærer med et tørringstrin i fluidiseret leje
US6913767B1 (en) 1993-10-25 2005-07-05 Genentech, Inc. Compositions for microencapsulation of antigens for use as vaccines
US6080429A (en) * 1993-10-25 2000-06-27 Genentech, Inc. Method for drying microspheres
KR100354270B1 (ko) 1993-11-19 2003-02-11 알커메스 컨트롤드 테라포이틱스 인코퍼레이티드 Ii 마이크로캡슐화된3-피페리디닐-치환된1,2-벤즈이속사졸및1,2-벤즈이소티아졸
US5902565A (en) * 1993-12-24 1999-05-11 Csl Limited Spray dried vaccine preparation comprising aluminium adsorbed immunogens
US6531156B1 (en) 1994-04-15 2003-03-11 Temple University Aqueous solven encapsulation method, apparatus and microcapsules
KR100201352B1 (ko) * 1995-03-16 1999-06-15 성재갑 단일주사 백신 제형
US6265389B1 (en) 1995-08-31 2001-07-24 Alkermes Controlled Therapeutics, Inc. Microencapsulation and sustained release of oligonucleotides
WO1997007788A2 (en) * 1995-08-31 1997-03-06 Alkermes Controlled Therapeutics, Inc. Composition for sustained release of an agent
ATE192334T1 (de) * 1995-11-09 2000-05-15 Microbiological Res Authority Mikroverkapselte dna zur impfung und gentherapie
US6270795B1 (en) 1995-11-09 2001-08-07 Microbiological Research Authority Method of making microencapsulated DNA for vaccination and gene therapy
DE19545257A1 (de) * 1995-11-24 1997-06-19 Schering Ag Verfahren zur Herstellung von morphologisch einheitlichen Mikrokapseln sowie nach diesem Verfahren hergestellte Mikrokapseln
US5980948A (en) * 1996-08-16 1999-11-09 Osteotech, Inc. Polyetherester copolymers as drug delivery matrices
US5783567A (en) * 1997-01-22 1998-07-21 Pangaea Pharmaceuticals, Inc. Microparticles for delivery of nucleic acid
US6197229B1 (en) * 1997-12-12 2001-03-06 Massachusetts Institute Of Technology Method for high supercoiled DNA content microspheres
GB9810236D0 (en) 1998-05-13 1998-07-08 Microbiological Res Authority Improvements relating to encapsulation of bioactive agents
US6406719B1 (en) 1998-05-13 2002-06-18 Microbiological Research Authority Encapsulation of bioactive agents
EP1096957A1 (en) 1998-06-18 2001-05-09 Johns Hopkins University School of Medicine Methods and reagents for intramuscular delivery of nucleic acids
US7087236B1 (en) 1998-09-01 2006-08-08 Merrion Research I Limited Method for inducing a cell-mediated immune response and improved parenteral vaccine formulations thereof
WO2000012124A1 (en) 1998-09-01 2000-03-09 Elan Corporation, Plc Oral vaccine compositions
AU771552B2 (en) 1999-02-05 2004-03-25 Alk-Abello A/S Novel mucosal delivery system
DK2116257T3 (da) 2000-08-09 2013-02-04 Alk Abello As Parenterale vaccineformuleringer og anvendelser deraf
DE60229867D1 (de) * 2001-07-02 2008-12-24 Merrion Res Iii Ltd Zielgerichtete ligande gegen peyer's flecke- und/oder m-zellen
GB0300881D0 (en) * 2003-01-15 2003-02-12 Secr Defence Therapeutic treatment
JP6334214B2 (ja) * 2013-03-08 2018-05-30 学校法人慶應義塾 レーザーを用いた薬剤放出方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3823228A (en) * 1971-09-29 1974-07-09 Univ Illinois Tge virus vaccine
IL54167A (en) * 1977-03-14 1980-05-30 Baxter Travenol Lab Frangible protective sealing arrangement
AU526320B2 (en) * 1979-04-27 1983-01-06 Acme Fluid Foundry Pty. Ltd. Manway cover fastening assembly
AU567155B2 (en) * 1983-04-15 1987-11-12 Damon Biotech Inc. Capsules for releasing core material at constant rate
IL72106A (en) * 1983-06-22 1988-02-29 Univ Ohio State Res Found Process for microencapsulating a weakly acidic or basic organic compound
GB2144950A (en) * 1983-08-10 1985-03-13 Philips Electronic Associated Data transmission system

Also Published As

Publication number Publication date
EP0266119A2 (en) 1988-05-04
DE3750247D1 (de) 1994-08-25
NZ222278A (en) 1989-09-27
ES2056068T3 (es) 1994-10-01
IL84167A (en) 1991-04-15
AU7992987A (en) 1988-04-28
ATE108650T1 (de) 1994-08-15
DK557787D0 (da) 1987-10-23
EP0266119B1 (en) 1994-07-20
JPS63190833A (ja) 1988-08-08
CN1111157A (zh) 1995-11-08
DK557787A (da) 1988-04-25
KR900003559B1 (ko) 1990-05-21
IE872851L (en) 1988-04-24
KR880004800A (ko) 1988-06-27
HK122495A (en) 1995-08-04
ZA877946B (en) 1988-04-26
CA1331738C (en) 1994-08-30
EP0266119A3 (en) 1989-07-26
IE64786B1 (en) 1995-09-06
AU607439B2 (en) 1991-03-07
IL84167A0 (en) 1988-03-31
EP0266119B2 (en) 2005-05-04
DE3750247T2 (de) 1994-10-27
JP2741728B2 (ja) 1998-04-22

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