DK175310B1 - Fremgangsmåde til fremstilling af en thiazepinforbindelse - Google Patents

Fremgangsmåde til fremstilling af en thiazepinforbindelse Download PDF

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Publication number
DK175310B1
DK175310B1 DK198801130A DK113088A DK175310B1 DK 175310 B1 DK175310 B1 DK 175310B1 DK 198801130 A DK198801130 A DK 198801130A DK 113088 A DK113088 A DK 113088A DK 175310 B1 DK175310 B1 DK 175310B1
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DK
Denmark
Prior art keywords
compound
reaction
formula
process according
carried out
Prior art date
Application number
DK198801130A
Other languages
Danish (da)
English (en)
Other versions
DK113088D0 (da
DK113088A (da
Inventor
Alan Charles Barker
Robert Jeffrey Copeland
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of DK113088D0 publication Critical patent/DK113088D0/da
Publication of DK113088A publication Critical patent/DK113088A/da
Application granted granted Critical
Publication of DK175310B1 publication Critical patent/DK175310B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with two six-membered rings
    • C07D281/16—[b, f]-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK198801130A 1987-03-10 1988-03-02 Fremgangsmåde til fremstilling af en thiazepinforbindelse DK175310B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB878705574A GB8705574D0 (en) 1987-03-10 1987-03-10 Preparation of thiazepine compound
GB8705574 1987-03-10

Publications (3)

Publication Number Publication Date
DK113088D0 DK113088D0 (da) 1988-03-02
DK113088A DK113088A (da) 1988-09-11
DK175310B1 true DK175310B1 (da) 2004-08-16

Family

ID=10613643

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198801130A DK175310B1 (da) 1987-03-10 1988-03-02 Fremgangsmåde til fremstilling af en thiazepinforbindelse

Country Status (25)

Country Link
EP (1) EP0282236B1 (de)
JP (1) JPH0688991B2 (de)
KR (1) KR960007088B1 (de)
AR (1) AR245707A1 (de)
AT (1) ATE70271T1 (de)
AU (1) AU595099B2 (de)
CA (1) CA1337345C (de)
DD (1) DD271703A5 (de)
DE (1) DE3866735D1 (de)
DK (1) DK175310B1 (de)
ES (1) ES2037822T3 (de)
FI (1) FI87778C (de)
GB (2) GB8705574D0 (de)
GR (1) GR3003324T3 (de)
HU (1) HU202231B (de)
IE (1) IE61122B1 (de)
IL (1) IL85564A (de)
MW (1) MW388A1 (de)
MY (1) MY103221A (de)
NO (1) NO174421C (de)
NZ (1) NZ223813A (de)
PH (1) PH25529A (de)
PT (1) PT86934B (de)
ZA (1) ZA881350B (de)
ZW (1) ZW2188A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0396581B1 (de) * 1987-12-15 1992-01-15 Siemens Aktiengesellschaft Verfahren zur herstellung von drähten oder bändern aus hochtemperatur-supraleitern und dabei verwendeter hüllkörper
GB9109557D0 (en) * 1991-05-02 1991-06-26 Wellcome Found Chemical compounds
GB9611328D0 (en) * 1996-05-31 1996-08-07 Zeneca Ltd Pharmaceutical compositions
GB9716161D0 (en) * 1997-08-01 1997-10-08 Zeneca Ltd Process
GB9922271D0 (en) * 1999-09-21 1999-11-17 Zeneca Ltd Formulation
AU2003235435A1 (en) * 2002-03-20 2003-10-08 Teva Pharmaceutical Industries Ltd. Crystalline forms of quetiapine hemifumarate
KR100707050B1 (ko) 2002-11-28 2007-04-13 에스케이 주식회사 10Ｈ-디벤조[ｂ,ｆ][1,4]티아제핀-11-온의 제조방법
US7071331B2 (en) 2003-02-22 2006-07-04 Teva Pharmaceutical Industries Ltd. Synthesis of quetiapine and pharmaceutically acceptable salts thereof
US7053115B2 (en) 2003-04-07 2006-05-30 Hetero Drugs Limited Crystalline form of dorzolamide hydrochloride
ES2223294B2 (es) * 2003-08-08 2005-10-01 Vita Cientifica, S.L. Procedimiento de preparacion de un compuesto farmaceuticamente activo.
JP2007505865A (ja) 2003-09-23 2007-03-15 フェルミオン オサケ ユキチュア クエチアピンの製造
PL368245A1 (en) * 2004-05-28 2005-12-12 CELON PHARMA Sp.z o.o. Method for manufacture of quetiapine
KR101038389B1 (ko) * 2004-06-23 2011-06-01 에스케이바이오팜 주식회사 11-(4-[2-(2-히드록시에톡시)에틸]-1-피페라지닐)-디벤조[ｂ,ｆ][1,4]티아제핀의 제조방법
GB0425729D0 (en) * 2004-11-23 2004-12-22 Pliva Res & Dev Ltd Heterocyclic compounds
WO2006056772A2 (en) * 2004-11-23 2006-06-01 Pliva Hrvatska D.O.O. Salts of quetiapine
EP1841751A1 (de) 2005-01-24 2007-10-10 IPCA Laboratories Limited Grosstechnische herstellung von 11-[4-{2-(2-hydroxyethoxy)ethyl}-1-piperazinyl]dibenzo[b,f]-[1,4]thiazepin
ES2234447B1 (es) * 2005-03-07 2006-03-01 Union Quimico-Farmaceutica S.A. Procedimiento para la obtencion de un derivado de 11-(4-sustituido-1-piperazinil)dibenzo(b,f)(1,4)tiazepina.
WO2006113425A1 (en) 2005-04-14 2006-10-26 Teva Pharmaceutical Industries Ltd. Process for preparing quetiapine fumarate
WO2006135544A1 (en) * 2005-06-10 2006-12-21 Cambrex Charles City, Inc. SYNTHESIS OF 11-(4[-(2-HYDROXYETHOXY)ETHYL]-PIPERAZINYL)-DIBENZO[b,f][1,4]THIAZEPINE AND ITS FUMARATE SALT
WO2007004234A1 (en) * 2005-07-04 2007-01-11 Usv Limited A PROCESS FOR THE PREPARATION OF 2-[2-(4-DIBENZO[b,f] [L,4] THIAZEPIN-11-yl-1- PIPERAZINYL)ETHOXY] ETHANOL FUMARATE
GB0516603D0 (en) * 2005-08-12 2005-09-21 Sandoz Ag Processes for the preparation of organic compounds useful as serotonin receptor antagonists
EP1948628A1 (de) * 2005-10-28 2008-07-30 Fermion Oy Aufreinigung von quetiapinhemifumarat durch kristallisation
US20080287418A1 (en) 2007-05-16 2008-11-20 Astrazeneca Ab Extended Release Compositions and Methods for Their Manufacture
CA2711395A1 (en) 2008-01-31 2009-08-06 Fermion Oy A process for the preparation of quetiapine
CA2728675A1 (en) 2008-06-20 2009-12-23 Astrazeneca Ab Dibenzothiazepine derivatives and use thereof
SI2262486T1 (sl) 2008-08-01 2013-04-30 Krka, Tovarna Zdravil, D.D., Novo Mesto Sestavek kvetiapina
EP2153834A3 (de) 2008-08-07 2010-02-24 Farmaprojects, S.A. Pharmazeutische Zusammensetzungen mit anhaltender Freisetzung, die Quetiapinsalze umfassen
CN101676275B (zh) * 2008-09-17 2014-05-07 北京德众万全药物技术开发有限公司 一种富马酸喹硫平的制备方法
WO2010089259A2 (en) 2009-02-04 2010-08-12 Woerwag R&D Gmbh Sustained release composition containing quetiapine
JP2012519683A (ja) 2009-03-04 2012-08-30 ランバクシー ラボラトリーズ リミテッド フマル酸クエチアピンの調製方法
WO2011121602A1 (en) 2010-03-29 2011-10-06 Hikal Limited Process for preparation of dibenzothiazepinone compounds
TR201008261A1 (tr) 2010-10-08 2012-04-24 Sanovel İlaç San. Ve Ti̇c. A.Ş. Kontrollü salım gerçekleştiren ketiapin formülasyonları
EP2848244A1 (de) 2013-09-16 2015-03-18 Yildiz Özsoy Erginer Tablettenformulierungen mit verzögerter Freisetzung aus Quetiapin
CN103524455A (zh) * 2013-10-30 2014-01-22 苏州敬业医药化工有限公司 一种制备2-氯-二苯并[b,f][1,4]硫氮杂卓-11-[10H]酮的方法
CN104447615A (zh) * 2014-02-28 2015-03-25 广东东阳光药业有限公司 喹硫平中间体的制备方法
CN104016945B (zh) * 2014-05-27 2016-06-29 渭南畅通药化科技有限公司 一种半富马酸喹硫平的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792426A (fr) * 1971-12-09 1973-06-07 Wander Ag Dr A Nouveaux derives de la dibenzo(b,f)(1,4)thiazepine, leur preparation etleur application comme medicaments
JPS60155171A (ja) * 1983-12-10 1985-08-15 Wako Pure Chem Ind Ltd ポリメトキシベンジルピペラジン誘導体
GB8607684D0 (en) * 1986-03-27 1986-04-30 Ici America Inc Thiazepine compounds

Also Published As

Publication number Publication date
DE3866735D1 (de) 1992-01-23
FI87778C (fi) 1993-02-25
JPH0688991B2 (ja) 1994-11-09
NZ223813A (en) 1990-11-27
DD271703A5 (de) 1989-09-13
DK113088D0 (da) 1988-03-02
GB8705574D0 (en) 1987-04-15
HU202231B (en) 1991-02-28
KR960007088B1 (ko) 1996-05-27
ZA881350B (en) 1988-12-28
CA1337345C (en) 1995-10-17
PT86934A (pt) 1988-04-01
MY103221A (en) 1993-05-29
ES2037822T3 (es) 1993-07-01
FI881087A (fi) 1988-09-11
GB8804063D0 (en) 1988-03-23
AU1237888A (en) 1988-09-08
NO174421B (no) 1994-01-24
PH25529A (en) 1991-07-24
EP0282236A1 (de) 1988-09-14
IL85564A (en) 1992-05-25
PT86934B (pt) 1992-05-29
NO881044D0 (no) 1988-03-09
IE880507L (en) 1988-09-10
GR3003324T3 (en) 1993-02-17
JPS63243081A (ja) 1988-10-07
HUT50336A (en) 1990-01-29
AR245707A1 (es) 1994-02-28
ATE70271T1 (de) 1991-12-15
IE61122B1 (en) 1994-10-05
ZW2188A1 (en) 1989-10-04
EP0282236B1 (de) 1991-12-11
NO174421C (no) 1994-05-04
KR880011151A (ko) 1988-10-26
IL85564A0 (en) 1988-08-31
FI87778B (fi) 1992-11-13
NO881044L (no) 1988-09-12
AU595099B2 (en) 1990-03-22
DK113088A (da) 1988-09-11
FI881087A0 (fi) 1988-03-09
MW388A1 (en) 1988-10-12

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