ATE480561T1 - Verfahren zur festphasen-peptidsynthese - Google Patents

Verfahren zur festphasen-peptidsynthese

Info

Publication number
ATE480561T1
ATE480561T1 AT05796944T AT05796944T ATE480561T1 AT E480561 T1 ATE480561 T1 AT E480561T1 AT 05796944 T AT05796944 T AT 05796944T AT 05796944 T AT05796944 T AT 05796944T AT E480561 T1 ATE480561 T1 AT E480561T1
Authority
AT
Austria
Prior art keywords
solid phase
peptide synthesis
phase peptide
devised
synthesizing
Prior art date
Application number
AT05796944T
Other languages
English (en)
Inventor
Anne-Sophie Droz
Jasmine Schnidrig
Nicole Studer
Stephane Varray
Corinne Wenger
Oleg Werbitzky
Original Assignee
Lonza Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lonza Ag filed Critical Lonza Ag
Application granted granted Critical
Publication of ATE480561T1 publication Critical patent/ATE480561T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C07K1/042General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers characterised by the nature of the carrier

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT05796944T 2004-10-19 2005-10-19 Verfahren zur festphasen-peptidsynthese ATE480561T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04024812 2004-10-19
PCT/EP2005/011226 WO2006045503A1 (en) 2004-10-19 2005-10-19 Method for solid phase peptide synthesis

Publications (1)

Publication Number Publication Date
ATE480561T1 true ATE480561T1 (de) 2010-09-15

Family

ID=35427609

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05796944T ATE480561T1 (de) 2004-10-19 2005-10-19 Verfahren zur festphasen-peptidsynthese

Country Status (11)

Country Link
US (2) USRE46830E1 (de)
EP (1) EP1737889B1 (de)
JP (1) JP4903709B2 (de)
CN (2) CN101094867B (de)
AT (1) ATE480561T1 (de)
DE (1) DE602005023429D1 (de)
DK (1) DK1737889T3 (de)
ES (1) ES2352204T3 (de)
IL (1) IL182698A (de)
PT (1) PT1737889E (de)
WO (1) WO2006045503A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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US7582727B1 (en) 2008-07-27 2009-09-01 The Medicinces Company Pharmaceutical formulations of bivalirudin and processes of making the same
US8252896B2 (en) * 2008-09-03 2012-08-28 ScnioPharm Taiwan, Ltd. Process for making bivalirudin
MX2011006950A (es) * 2008-12-29 2011-07-28 Lonza Braine S A Proceso para la produccion de bivalirudina.
CN101475631B (zh) * 2009-01-08 2011-08-17 苏州中科天马肽工程中心有限公司 比伐卢定的液相合成方法
US20110160431A1 (en) 2009-04-06 2011-06-30 Novetide, Ltd. Production of peptides containing poly-gly sequences using fmoc chemistry
CN101555274B (zh) * 2009-05-15 2013-08-21 海南双成药业股份有限公司 一种多肽固相合成比法卢定粗品的制备方法
WO2013042129A1 (en) 2011-09-23 2013-03-28 Natco Pharma Limited Improved process for preparation of bivalirudin
US9388212B2 (en) 2013-02-21 2016-07-12 Chemical & Biopharmaceutical Laboratories Of Patras S.A. Solid phase peptide synthesis via side chain attachment
JP6382488B2 (ja) * 2013-02-21 2018-08-29 ケミカル アンド バイオファーマシューティカル ラボラトリーズ オブ パトラ エス.エー. 側鎖結合を介する固相ペプチド合成
GB201310921D0 (en) 2013-06-19 2013-07-31 Chemical & Biopharmaceutical Lab Of Patras S A Peptide-resin conjugate and use thereof
EP3199540A4 (de) * 2014-09-26 2018-05-09 Kaneka Corporation Verfahren zur herstellung von hydrophoben peptiden
CN108383905A (zh) * 2016-12-30 2018-08-10 江苏金斯瑞生物科技有限公司 一种比伐卢定的制备方法
CN112111001B (zh) * 2019-06-19 2021-10-29 翰宇药业(武汉)有限公司 胸腺肽Tα-1的合成方法
JP2020138975A (ja) * 2020-05-18 2020-09-03 ケミカル アンド バイオファーマシューティカル ラボラトリーズ オブ パトラ エス.エー. 側鎖結合を介する固相ペプチド合成

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CN102336813B (zh) 2011-07-01 2016-01-06 上海苏豪逸明制药有限公司 一种固相多肽合成蛋白溶菌素的制备方法
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CN102641506B (zh) 2012-04-11 2013-10-23 承德医学院中药研究所 比伐卢定-聚乙二醇化复合物
CN102731624B (zh) 2012-06-14 2015-09-23 无锡市凯利药业有限公司 一种固相片段法合成比伐卢定的方法
CN102702325B (zh) 2012-06-19 2015-09-23 深圳翰宇药业股份有限公司 一种抗凝血多肽的制备方法
CN102924575B (zh) 2012-10-31 2014-12-31 深圳翰宇药业股份有限公司 一种比伐卢定的制备方法

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US20080287648A1 (en) 2008-11-20
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CN102225966A (zh) 2011-10-26
IL182698A0 (en) 2007-09-20
WO2006045503A1 (en) 2006-05-04
USRE46830E1 (en) 2018-05-08
EP1737889B1 (de) 2010-09-08
IL182698A (en) 2013-11-28
DK1737889T3 (da) 2011-01-03
JP2008517018A (ja) 2008-05-22
EP1737889A1 (de) 2007-01-03
CN101094867B (zh) 2011-08-24
CN102225966B (zh) 2012-12-26
PT1737889E (pt) 2010-12-13
US7939629B2 (en) 2011-05-10
JP4903709B2 (ja) 2012-03-28

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