DK172081A - Mercaptoforbindelse og fremgangsmaade til fremstilling deraf - Google Patents

Mercaptoforbindelse og fremgangsmaade til fremstilling deraf

Info

Publication number
DK172081A
DK172081A DK172081A DK172081A DK172081A DK 172081 A DK172081 A DK 172081A DK 172081 A DK172081 A DK 172081A DK 172081 A DK172081 A DK 172081A DK 172081 A DK172081 A DK 172081A
Authority
DK
Denmark
Prior art keywords
carbon atoms
residue
alkyl
amino acid
image
Prior art date
Application number
DK172081A
Other languages
English (en)
Inventor
N S Bodor
K B Sloan
S A Pogany
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of DK172081A publication Critical patent/DK172081A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • A61P5/12—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH for decreasing, blocking or antagonising the activity of the posterior pituitary hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/38—One sulfur atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/36—Sulfur atom
    • C07D473/38—Sulfur atom attached in position 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Furan Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Manufacturing Of Electrical Connectors (AREA)
  • Steroid Compounds (AREA)
DK172081A 1980-04-21 1981-04-15 Mercaptoforbindelse og fremgangsmaade til fremstilling deraf DK172081A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US14198180A 1980-04-21 1980-04-21

Publications (1)

Publication Number Publication Date
DK172081A true DK172081A (da) 1981-10-22

Family

ID=22498074

Family Applications (1)

Application Number Title Priority Date Filing Date
DK172081A DK172081A (da) 1980-04-21 1981-04-15 Mercaptoforbindelse og fremgangsmaade til fremstilling deraf

Country Status (10)

Country Link
US (1) US4443435A (da)
EP (1) EP0038541B1 (da)
JP (1) JPS572252A (da)
AT (1) ATE21388T1 (da)
DE (1) DE3175100D1 (da)
DK (1) DK172081A (da)
ES (1) ES8301197A1 (da)
GR (1) GR75219B (da)
IE (1) IE52017B1 (da)
PT (1) PT72877B (da)

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US5823679A (en) * 1993-09-17 1998-10-20 Omega Engineering, Inc. Method and apparatus for measuring temperature including aiming light
FR2773213B1 (fr) 1996-12-11 2001-08-24 Omega Engineering Procede et dispositif pour la mesure par infrarouge de la temperature d'une surface
DE69810852T2 (de) * 1997-07-17 2003-06-05 Kawasaki Steel Co Kornorientiertes Elektrostahlblech mit ausgezeichneten magnetischen Eigenschaften und dessen Herstellungsverfahren
CN1321215C (zh) 2001-07-16 2007-06-13 新日本制铁株式会社 高磁场铁损和涂层特性优异的超高磁通密度单取向电工钢板及其制造方法
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EP1746975A2 (en) * 2004-04-01 2007-01-31 Teva Pharmaceutical Industries Limited Delayed release formulations of 6-mercaptopurine
JP5419459B2 (ja) 2006-11-22 2014-02-19 新日鐵住金株式会社 被膜密着性に優れた一方向性電磁鋼板およびその製造法
EP2573069A3 (en) 2006-12-19 2013-05-22 MethylGene Inc. Inhibitors of histone deacetylase and prodrugs thereof
WO2009128955A1 (en) * 2008-04-18 2009-10-22 Teva Pharmaceutical Industries Ltd. Treatment of inflammatory bowel disease with 6-mercaptopurine
JP5927754B2 (ja) 2010-06-29 2016-06-01 Ｊｆｅスチール株式会社 方向性電磁鋼板およびその製造方法
JP5923879B2 (ja) 2010-06-29 2016-05-25 Ｊｆｅスチール株式会社 方向性電磁鋼板およびその製造方法
JP5998424B2 (ja) 2010-08-06 2016-09-28 Ｊｆｅスチール株式会社 方向性電磁鋼板
JP5853352B2 (ja) 2010-08-06 2016-02-09 Ｊｆｅスチール株式会社 方向性電磁鋼板およびその製造方法
BR112013001358B1 (pt) 2010-08-06 2019-07-02 Jfe Steel Corporation Chapa de aço elétrico de grãos orientados e método para a fabricação da mesma
JP5593942B2 (ja) 2010-08-06 2014-09-24 Ｊｆｅスチール株式会社 方向性電磁鋼板およびその製造方法
JP5447738B2 (ja) 2011-12-26 2014-03-19 Ｊｆｅスチール株式会社 方向性電磁鋼板
EP2799561B1 (en) 2011-12-27 2019-11-27 JFE Steel Corporation Device to improve iron loss properties of grain-oriented electrical steel sheet
RU2570250C1 (ru) 2011-12-27 2015-12-10 ДжФЕ СТИЛ КОРПОРЕЙШН Текстурированный лист из электротехнической стали
EP2799566B1 (en) 2011-12-28 2019-04-17 JFE Steel Corporation Grain-oriented electrical steel sheet and method for improving iron loss properties thereof
US10804015B2 (en) 2011-12-29 2020-10-13 Posco Electrical steel sheet and method for manufacturing the same
KR101636191B1 (ko) 2012-04-26 2016-07-04 제이에프이 스틸 가부시키가이샤 방향성 전기 강판 및 그 제조 방법
JP5971157B2 (ja) 2013-03-11 2016-08-17 Ｊｆｅスチール株式会社 塗布装置および塗布方法
JP5668795B2 (ja) 2013-06-19 2015-02-12 Ｊｆｅスチール株式会社 方向性電磁鋼板およびそれを用いた変圧器鉄心
KR101677883B1 (ko) 2013-09-19 2016-11-18 제이에프이 스틸 가부시키가이샤 방향성 전기 강판 및 그 제조 방법
JP6215673B2 (ja) 2013-11-29 2017-10-18 東芝産業機器システム株式会社 ベクトル磁気特性制御材、および、鉄心
KR101639920B1 (ko) 2014-12-26 2016-07-15 주식회사 포스코 방향성 전기강판의 자구미세화 장치 및 그 방법
WO2017066619A1 (en) 2015-10-16 2017-04-20 Teva Pharmaceutical Industries Ltd. Treatment of non-alcoholic fatty liver disease or non-alcoholic steatohepatitis with delayed-release 6-mercaptopurine
RU2717034C1 (ru) 2017-02-28 2020-03-17 ДжФЕ СТИЛ КОРПОРЕЙШН Текстурированная электротехническая листовая сталь и способ ее производства
KR20230109739A (ko) 2020-11-27 2023-07-20 제이에프이 스틸 가부시키가이샤 방향성 전자 강판 및 그의 제조 방법
CN115724824B (zh) * 2021-09-01 2024-03-15 四川大学 3-(酰胺烷硫基)苯酞类化合物、其制备方法和用途

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GR75219B (da) * 1980-04-21 1984-07-13 Merck & Co Inc

Also Published As

Publication number Publication date
ES501496A0 (es) 1982-12-01
EP0038541B1 (en) 1986-08-13
IE52017B1 (en) 1987-05-27
IE810869L (en) 1982-10-21
US4443435A (en) 1984-04-17
EP0038541A1 (en) 1981-10-28
PT72877A (en) 1981-05-01
ATE21388T1 (de) 1986-08-15
JPH0226630B2 (da) 1990-06-12
GR75219B (da) 1984-07-13
JPS572252A (en) 1982-01-07
DE3175100D1 (en) 1986-09-18
PT72877B (en) 1983-03-29
ES8301197A1 (es) 1982-12-01

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Legal Events

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AHS Application shelved for other reasons than non-payment
B1 Patent granted (law 1993)
PBP Patent lapsed