DK169506B1 - Anvendelse af Podophyllotoxin og derivater deraf til fremstilling af farmaceutiske præparater til behandling af forskellige sygdomme - Google Patents

Anvendelse af Podophyllotoxin og derivater deraf til fremstilling af farmaceutiske præparater til behandling af forskellige sygdomme Download PDF

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Publication number
DK169506B1
DK169506B1 DK408186A DK408186A DK169506B1 DK 169506 B1 DK169506 B1 DK 169506B1 DK 408186 A DK408186 A DK 408186A DK 408186 A DK408186 A DK 408186A DK 169506 B1 DK169506 B1 DK 169506B1
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DK
Denmark
Prior art keywords
podophyllotoxin
derivatives
pharmaceutical preparations
various diseases
treating various
Prior art date
Application number
DK408186A
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Danish (da)
English (en)
Other versions
DK408186A (da
DK408186D0 (da
Inventor
Boerje Rosen
Kurt Leander
Original Assignee
Conpharm Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conpharm Ab filed Critical Conpharm Ab
Publication of DK408186A publication Critical patent/DK408186A/da
Publication of DK408186D0 publication Critical patent/DK408186D0/da
Application granted granted Critical
Publication of DK169506B1 publication Critical patent/DK169506B1/da

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D493/00Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK408186A 1984-12-28 1986-08-27 Anvendelse af Podophyllotoxin og derivater deraf til fremstilling af farmaceutiske præparater til behandling af forskellige sygdomme DK169506B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE8406660 1984-12-28
SE8406660 1984-12-28
SE8500541 1985-12-20
PCT/SE1985/000541 WO1986004062A1 (fr) 1984-12-28 1985-12-20 Compose pharmaceutiquement actif et son procede de preparation

Publications (3)

Publication Number Publication Date
DK408186A DK408186A (da) 1986-08-27
DK408186D0 DK408186D0 (da) 1986-08-27
DK169506B1 true DK169506B1 (da) 1994-11-14

Family

ID=20358339

Family Applications (1)

Application Number Title Priority Date Filing Date
DK408186A DK169506B1 (da) 1984-12-28 1986-08-27 Anvendelse af Podophyllotoxin og derivater deraf til fremstilling af farmaceutiske præparater til behandling af forskellige sygdomme

Country Status (23)

Country Link
US (1) US4788216A (fr)
EP (1) EP0207124B1 (fr)
JP (2) JPH0720966B2 (fr)
CN (1) CN1006795B (fr)
AP (1) AP32A (fr)
AT (1) ATE68186T1 (fr)
AU (1) AU585936B2 (fr)
CA (1) CA1255230A (fr)
DE (1) DE3584370D1 (fr)
DK (1) DK169506B1 (fr)
DZ (1) DZ876A1 (fr)
EG (1) EG17788A (fr)
ES (1) ES8701761A1 (fr)
FI (1) FI89330C (fr)
GR (1) GR853145B (fr)
HU (1) HU201672B (fr)
IL (1) IL77456A (fr)
MA (1) MA20602A1 (fr)
NO (1) NO863329L (fr)
PT (1) PT81760B (fr)
TN (1) TNSN86004A1 (fr)
WO (1) WO1986004062A1 (fr)
ZA (1) ZA859881B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4644072A (en) * 1985-04-12 1987-02-17 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
DE69033342T2 (de) * 1989-02-23 2000-05-11 Univ North Carolina Etoposidanaloge
SE464167B (sv) 1989-07-31 1991-03-18 Analytecon Sa Topisk farmaceutisk beredning av podophyllotoxin
US5332811A (en) * 1989-09-12 1994-07-26 The University Of North Carolina At Chapel Hill Etopside analogs
US5338867A (en) * 1992-04-24 1994-08-16 Genelabs Technologies, Inc. Preparation of 4β- amino podophyllotoxin compounds
SE9301831D0 (sv) * 1993-05-28 1993-05-28 Analytecon S A Pharmaceutical compositions
GB9422947D0 (en) * 1994-11-14 1995-01-04 Univ Salamanca Immunosuppressive cyclolignan derivatives
US6051721A (en) * 1997-10-02 2000-04-18 The Board Of Regents Of The University Of Nebraska Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
FI105152B (fi) * 1998-07-17 2000-06-30 Eero Saarela Paikallinen kivunlievitysmenetelmä
US6143304A (en) * 1999-08-17 2000-11-07 The University Of Mississippi Enhanced yield of podophyllotoxin from natural products through in situ conversion methods
DE60233601D1 (de) * 2001-06-19 2009-10-15 Axelar Ab Verwendung von bestimmten Cyclolignanen
SE0102168D0 (sv) * 2001-06-19 2001-06-19 Karolinska Innovations Ab New use and new compounds
SE0203746D0 (sv) * 2002-12-18 2002-12-18 Karolinska Innovations Ab New compounds
EP2303261A4 (fr) * 2008-06-23 2011-09-07 Axelar Ab Utilisation de cyclolignanes pour le traitement d un système immunitaire hyperactif
WO2013124380A1 (fr) * 2012-02-24 2013-08-29 Nestec S.A. Peltatine destinée à être utilisée pour traiter des troubles inflammatoires chroniques
WO2015028456A1 (fr) * 2013-08-28 2015-03-05 Nestec S.A. Modulateurs des rapp
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA635769A (en) * 1962-01-30 Rutschmann Jurg Amides of podophyllic acid and picropodophyllic acid
SE335139B (fr) * 1964-08-12 1971-05-17 Sandoz Ag
US4122092A (en) * 1977-08-25 1978-10-24 University Of Rochester Total synthesis of (±)-picropodophyllone and (±)-4'-demethylpicropodophyllone
US4567253A (en) * 1984-02-03 1986-01-28 Tony Durst 2-Substituted derivatives of podophyllotoxin and etoposide
GB8424269D0 (en) * 1984-09-26 1984-10-31 Pharma Medica As Isolation and purification of podophyllotoxin

Also Published As

Publication number Publication date
DK408186A (da) 1986-08-27
NO863329D0 (no) 1986-08-19
US4788216A (en) 1988-11-29
FI89330B (fi) 1993-06-15
ATE68186T1 (de) 1991-10-15
ES550504A0 (es) 1986-12-01
HUT47582A (en) 1989-03-28
IL77456A0 (en) 1986-08-31
ZA859881B (en) 1986-09-24
JP2572558B2 (ja) 1997-01-16
EP0207124A1 (fr) 1987-01-07
CN85109666A (zh) 1986-10-29
CA1255230A (fr) 1989-06-06
FI89330C (fi) 1993-09-27
HU201672B (en) 1990-12-28
GR853145B (fr) 1986-04-29
MA20602A1 (fr) 1986-07-01
PT81760A (en) 1986-01-02
AU5300386A (en) 1986-07-29
JPH07173063A (ja) 1995-07-11
AP32A (en) 1988-12-07
PT81760B (pt) 1987-11-11
IL77456A (en) 1989-07-31
NO863329L (no) 1986-08-19
JPH0720966B2 (ja) 1995-03-08
WO1986004062A1 (fr) 1986-07-17
EP0207124B1 (fr) 1991-10-09
TNSN86004A1 (fr) 1990-01-01
JPS62501360A (ja) 1987-06-04
DK408186D0 (da) 1986-08-27
DE3584370D1 (de) 1991-11-14
CN1006795B (zh) 1990-02-14
FI863482A0 (fi) 1986-08-27
AP8500017A0 (en) 1985-11-01
DZ876A1 (fr) 2004-09-13
AU585936B2 (en) 1989-06-29
FI863482A (fi) 1986-08-27
EG17788A (en) 1990-12-30
ES8701761A1 (es) 1986-12-01

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Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed