IL77456A - Preparation of pure podophyllotoxin and its derivatives and pharmaceutical compositions containing them - Google Patents

Preparation of pure podophyllotoxin and its derivatives and pharmaceutical compositions containing them

Info

Publication number
IL77456A
IL77456A IL77456A IL7745685A IL77456A IL 77456 A IL77456 A IL 77456A IL 77456 A IL77456 A IL 77456A IL 7745685 A IL7745685 A IL 7745685A IL 77456 A IL77456 A IL 77456A
Authority
IL
Israel
Prior art keywords
derivatives
preparation
pharmaceutical compositions
compositions containing
podophyllotoxin
Prior art date
Application number
IL77456A
Other languages
English (en)
Other versions
IL77456A0 (en
Original Assignee
Conpharm Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Conpharm Ab filed Critical Conpharm Ab
Publication of IL77456A0 publication Critical patent/IL77456A0/xx
Publication of IL77456A publication Critical patent/IL77456A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Rheumatology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pain & Pain Management (AREA)
  • Virology (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL77456A 1984-12-28 1985-12-26 Preparation of pure podophyllotoxin and its derivatives and pharmaceutical compositions containing them IL77456A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8406660 1984-12-28

Publications (2)

Publication Number Publication Date
IL77456A0 IL77456A0 (en) 1986-08-31
IL77456A true IL77456A (en) 1989-07-31

Family

ID=20358339

Family Applications (1)

Application Number Title Priority Date Filing Date
IL77456A IL77456A (en) 1984-12-28 1985-12-26 Preparation of pure podophyllotoxin and its derivatives and pharmaceutical compositions containing them

Country Status (23)

Country Link
US (1) US4788216A (fr)
EP (1) EP0207124B1 (fr)
JP (2) JPH0720966B2 (fr)
CN (1) CN1006795B (fr)
AP (1) AP32A (fr)
AT (1) ATE68186T1 (fr)
AU (1) AU585936B2 (fr)
CA (1) CA1255230A (fr)
DE (1) DE3584370D1 (fr)
DK (1) DK169506B1 (fr)
DZ (1) DZ876A1 (fr)
EG (1) EG17788A (fr)
ES (1) ES8701761A1 (fr)
FI (1) FI89330C (fr)
GR (1) GR853145B (fr)
HU (1) HU201672B (fr)
IL (1) IL77456A (fr)
MA (1) MA20602A1 (fr)
NO (1) NO863329L (fr)
PT (1) PT81760B (fr)
TN (1) TNSN86004A1 (fr)
WO (1) WO1986004062A1 (fr)
ZA (1) ZA859881B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4644072A (en) * 1985-04-12 1987-02-17 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
DE69033342T2 (de) * 1989-02-23 2000-05-11 Univ North Carolina Etoposidanaloge
SE464167B (sv) 1989-07-31 1991-03-18 Analytecon Sa Topisk farmaceutisk beredning av podophyllotoxin
US5332811A (en) * 1989-09-12 1994-07-26 The University Of North Carolina At Chapel Hill Etopside analogs
US5338867A (en) * 1992-04-24 1994-08-16 Genelabs Technologies, Inc. Preparation of 4β- amino podophyllotoxin compounds
SE9301831D0 (sv) * 1993-05-28 1993-05-28 Analytecon S A Pharmaceutical compositions
GB9422947D0 (en) * 1994-11-14 1995-01-04 Univ Salamanca Immunosuppressive cyclolignan derivatives
US6051721A (en) * 1997-10-02 2000-04-18 The Board Of Regents Of The University Of Nebraska Ring E-modified analogues of(-)-podophyllotoxin and etoposide and a method for their synthesis
FI105152B (fi) * 1998-07-17 2000-06-30 Eero Saarela Paikallinen kivunlievitysmenetelmä
US6143304A (en) * 1999-08-17 2000-11-07 The University Of Mississippi Enhanced yield of podophyllotoxin from natural products through in situ conversion methods
DE60233601D1 (de) * 2001-06-19 2009-10-15 Axelar Ab Verwendung von bestimmten Cyclolignanen
SE0102168D0 (sv) * 2001-06-19 2001-06-19 Karolinska Innovations Ab New use and new compounds
SE0203746D0 (sv) * 2002-12-18 2002-12-18 Karolinska Innovations Ab New compounds
EP2303261A4 (fr) * 2008-06-23 2011-09-07 Axelar Ab Utilisation de cyclolignanes pour le traitement d un système immunitaire hyperactif
WO2013124380A1 (fr) * 2012-02-24 2013-08-29 Nestec S.A. Peltatine destinée à être utilisée pour traiter des troubles inflammatoires chroniques
WO2015028456A1 (fr) * 2013-08-28 2015-03-05 Nestec S.A. Modulateurs des rapp
JOP20190254A1 (ar) 2017-04-27 2019-10-27 Pharma Mar Sa مركبات مضادة للأورام

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA635769A (en) * 1962-01-30 Rutschmann Jurg Amides of podophyllic acid and picropodophyllic acid
SE335139B (fr) * 1964-08-12 1971-05-17 Sandoz Ag
US4122092A (en) * 1977-08-25 1978-10-24 University Of Rochester Total synthesis of (±)-picropodophyllone and (±)-4'-demethylpicropodophyllone
US4567253A (en) * 1984-02-03 1986-01-28 Tony Durst 2-Substituted derivatives of podophyllotoxin and etoposide
GB8424269D0 (en) * 1984-09-26 1984-10-31 Pharma Medica As Isolation and purification of podophyllotoxin

Also Published As

Publication number Publication date
DK408186A (da) 1986-08-27
NO863329D0 (no) 1986-08-19
US4788216A (en) 1988-11-29
FI89330B (fi) 1993-06-15
ATE68186T1 (de) 1991-10-15
ES550504A0 (es) 1986-12-01
HUT47582A (en) 1989-03-28
IL77456A0 (en) 1986-08-31
ZA859881B (en) 1986-09-24
JP2572558B2 (ja) 1997-01-16
EP0207124A1 (fr) 1987-01-07
CN85109666A (zh) 1986-10-29
CA1255230A (fr) 1989-06-06
FI89330C (fi) 1993-09-27
HU201672B (en) 1990-12-28
GR853145B (fr) 1986-04-29
MA20602A1 (fr) 1986-07-01
PT81760A (en) 1986-01-02
AU5300386A (en) 1986-07-29
JPH07173063A (ja) 1995-07-11
AP32A (en) 1988-12-07
PT81760B (pt) 1987-11-11
NO863329L (no) 1986-08-19
JPH0720966B2 (ja) 1995-03-08
WO1986004062A1 (fr) 1986-07-17
EP0207124B1 (fr) 1991-10-09
TNSN86004A1 (fr) 1990-01-01
JPS62501360A (ja) 1987-06-04
DK408186D0 (da) 1986-08-27
DK169506B1 (da) 1994-11-14
DE3584370D1 (de) 1991-11-14
CN1006795B (zh) 1990-02-14
FI863482A0 (fi) 1986-08-27
AP8500017A0 (en) 1985-11-01
DZ876A1 (fr) 2004-09-13
AU585936B2 (en) 1989-06-29
FI863482A (fi) 1986-08-27
EG17788A (en) 1990-12-30
ES8701761A1 (es) 1986-12-01

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Legal Events

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KB Patent renewed
KB Patent renewed