DK1681299T3 - Fremgangsmåde til rensning af højt anioniske proteiner - Google Patents

Fremgangsmåde til rensning af højt anioniske proteiner

Info

Publication number
DK1681299T3
DK1681299T3 DK06006740.2T DK06006740T DK1681299T3 DK 1681299 T3 DK1681299 T3 DK 1681299T3 DK 06006740 T DK06006740 T DK 06006740T DK 1681299 T3 DK1681299 T3 DK 1681299T3
Authority
DK
Denmark
Prior art keywords
purification
proteins
highly anionic
sulfations
sulfated
Prior art date
Application number
DK06006740.2T
Other languages
English (en)
Inventor
Jonathan L Coffman
William Barry Foster
Bonnie J Germain
Shujun Sun
Jeffrey J Robinson
Original Assignee
Genetics Inst Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst Llc filed Critical Genetics Inst Llc
Application granted granted Critical
Publication of DK1681299T3 publication Critical patent/DK1681299T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/20—Partition-, reverse-phase or hydrophobic interaction chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70596—Molecules with a "CD"-designation not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
DK06006740.2T 2000-03-27 2001-03-27 Fremgangsmåde til rensning af højt anioniske proteiner DK1681299T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19335100P 2000-03-27 2000-03-27
EP01922750A EP1268514B1 (en) 2000-03-27 2001-03-27 Methods for purifying highly anionic proteins

Publications (1)

Publication Number Publication Date
DK1681299T3 true DK1681299T3 (da) 2010-02-01

Family

ID=22713294

Family Applications (3)

Application Number Title Priority Date Filing Date
DK06006740.2T DK1681299T3 (da) 2000-03-27 2001-03-27 Fremgangsmåde til rensning af højt anioniske proteiner
DK01922750T DK1268514T3 (da) 2000-03-27 2001-03-27 Fremgangsmåde til oprensning af særdeles anioniske proteiner
DK06006739.4T DK1681298T3 (da) 2000-03-27 2001-03-27 Fremgangsmåder til oprensning af særdeles anioniske proteiner

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK01922750T DK1268514T3 (da) 2000-03-27 2001-03-27 Fremgangsmåde til oprensning af særdeles anioniske proteiner
DK06006739.4T DK1681298T3 (da) 2000-03-27 2001-03-27 Fremgangsmåder til oprensning af særdeles anioniske proteiner

Country Status (11)

Country Link
US (1) US6933370B2 (da)
EP (3) EP1681298B1 (da)
JP (2) JP5025874B2 (da)
AT (3) ATE328895T1 (da)
AU (2) AU2001249515B2 (da)
CA (1) CA2404155C (da)
DE (3) DE60141657D1 (da)
DK (3) DK1681299T3 (da)
ES (3) ES2338687T3 (da)
NZ (1) NZ521578A (da)
WO (1) WO2001072769A2 (da)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60231016D1 (de) * 2001-06-05 2009-03-12 Genetics Inst Llc Verfahren zur Reinigung stark anionischer Proteine
AU2003233008B2 (en) * 2002-04-22 2008-04-24 Recopharma Ab Fusion polypeptides and methods for inhibiting microbial adhesion
ATE462716T1 (de) 2003-10-24 2010-04-15 Amgen Inc Verfahren zur aufreinigung von proteinen in einer durchflussfraktion aus der chromatographie mit hydrophoben wechselwirkungen
WO2007002570A1 (en) * 2005-06-24 2007-01-04 Desert Lake Technologies Purified component of blue-green algae and method of use
EP1969007B1 (en) * 2005-12-20 2013-08-28 Bristol-Myers Squibb Company Compositions and methods for producing a composition
AR058568A1 (es) 2005-12-20 2008-02-13 Bristol Myers Squibb Co Metodos para producir una composicion con moleculas ctla4-ig a partir de un medio de cultivo
JP5448825B2 (ja) * 2006-10-19 2014-03-19 ヤンセン バイオテツク，インコーポレーテツド 非凝集抗体Ｆｃドメインの製造方法
WO2011090720A2 (en) * 2009-12-29 2011-07-28 Dr. Reddy's Laboratories Ltd Purification of proteins
CA2787897A1 (en) * 2010-02-12 2011-08-18 Dsm Ip Assets B.V. Single unit antibody purification
WO2012040216A1 (en) 2010-09-20 2012-03-29 Bio-Rad Laboratories, Inc. Dissociation of product-complexed contaminants in chromatography
US20200123251A1 (en) * 2016-10-28 2020-04-23 Merck Sharp & Dohme Corp. Purification Process for Removal of Tyrosine Sulfation Antibody Variants; Purified Compositions
EP3580231A1 (en) * 2017-02-09 2019-12-18 Bracco Suisse SA Process for the purification of soluble psgl-1 protein variants
US11447547B1 (en) 2017-12-13 2022-09-20 Amgen Inc. Method of antigen-binding protein production

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4723000A (en) * 1983-07-05 1988-02-02 Biospectrum, Inc. Human interferon gamma and interleukin-2
US5115101A (en) 1988-06-08 1992-05-19 Miles Inc. Removal of protein A from antibody preparations
US5378464A (en) * 1989-03-08 1995-01-03 Board Of Regents Of The University Of Oklahoma Modulation of inflammatory responses by administration of GMP-140 or antibody to GMP-140
US5464778A (en) 1989-03-08 1995-11-07 Board Of Regents Of The University Of Oklahoma Glycoprotein ligand for P-selectin and methods of use thereof
US5034133A (en) * 1990-07-26 1991-07-23 Schering-Corporation Purification of human interleukin-4 from a CHO-cell line culture medium
US5530109A (en) * 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
US6277975B1 (en) * 1992-10-23 2001-08-21 Genetics Institute, Inc. Fusions of P-selectin ligand protein and polynucleotides encoding same
US5843707A (en) * 1992-10-23 1998-12-01 Genetics Institute, Inc. Nucleic acid encoding a novel P-selectin ligand protein
EP0666914B1 (en) * 1992-10-23 2003-12-10 Genetics Institute, LLC Novel p-selectin ligand protein
US5429746A (en) * 1994-02-22 1995-07-04 Smith Kline Beecham Corporation Antibody purification
ES2161793T3 (es) 1994-04-09 2001-12-16 Hoffmann La Roche Proceso para la produccion de alfa-interferona.
US6008328A (en) 1994-10-13 1999-12-28 Amgen Inc. Method for purifying keratinocyte growth factors
SE503424C2 (sv) 1994-11-14 1996-06-10 Pharmacia Ab Process för rening av rekombinant koagulationsfaktor VIII
FR2737730B1 (fr) 1995-08-10 1997-09-05 Pasteur Merieux Serums Vacc Procede de purification de virus par chromatographie
FR2738009B1 (fr) 1995-08-24 1997-10-31 Centre Nat Rech Scient Procede d'obtention de polysaccharides sulfates
WO1998021234A2 (en) * 1996-11-15 1998-05-22 Genentech, Inc. Purification of neurotrophins
WO1999019345A1 (en) * 1997-10-14 1999-04-22 Institute For Vaccine Development Method for purifying retroviral particles and soluble viral antigens

Also Published As

Publication number Publication date
EP1681298A2 (en) 2006-07-19
WO2001072769A3 (en) 2002-02-07
EP1681299A3 (en) 2006-12-27
JP2012184245A (ja) 2012-09-27
US20020132991A1 (en) 2002-09-19
DE60140493D1 (de) 2009-12-24
ATE328895T1 (de) 2006-06-15
JP2003528884A (ja) 2003-09-30
CA2404155C (en) 2011-08-09
DE60120374T2 (de) 2007-06-06
AU2001249515B2 (en) 2006-10-05
ES2266188T3 (es) 2007-03-01
EP1268514B1 (en) 2006-06-07
JP5596078B2 (ja) 2014-09-24
ES2338687T3 (es) 2010-05-11
EP1268514A2 (en) 2003-01-02
DK1268514T3 (da) 2006-10-09
CA2404155A1 (en) 2001-10-04
EP1681299A2 (en) 2006-07-19
JP5025874B2 (ja) 2012-09-12
US6933370B2 (en) 2005-08-23
EP1681298B1 (en) 2010-03-24
ATE461935T1 (de) 2010-04-15
ES2343023T3 (es) 2010-07-21
DE60141657D1 (de) 2010-05-06
DE60120374D1 (de) 2006-07-20
DK1681298T3 (da) 2010-06-14
ATE448241T1 (de) 2009-11-15
WO2001072769A2 (en) 2001-10-04
NZ521578A (en) 2004-08-27
EP1681298A3 (en) 2006-12-20
EP1681299B1 (en) 2009-11-11
AU4951501A (en) 2001-10-08
WO2001072769A9 (en) 2003-04-03

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